Anandh Babu Pon Velayutham, PhD is an Associate Professor in the Department of Nutrition & Integrative Physiology. He received his Ph.D. in Biochemistry from the University of Madras and subsequently completed postdoctoral training at Virginia Polytechnic Institute and State University. Dr. Velayutham joined the faculty at the University of Utah in 2012.
Research Statement
Diabetes greatly increases the risk of cardiovascular diseases, which accounts for the largest number of deaths among American diabetic patients. Dr. Velayutham’s research aims to determine potential non-pharmacological, lifestyle-oriented strategies to reduce the cardiovascular complications in diabetes. His current research investigates the vascular effects of blueberries and strawberries with special emphasis on the microbial metabolites of berry anthocyanins and the molecular signaling mechanisms involved. These studies will provide key insights toward understanding the causal association between dietary berries, gut microbiome and vascular health.
Selected Publications
Journal Article
- Kalita (12/15/2020). Visualizing antithrombin-binding 3-O-sulfated heparan sulfate motifs on cell surfaces. .
- C Petersen (04/2019). Dietary supplementation of strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice.
- Chrissa Petersen (04/09/2018). Circulating metabolites of strawberry mediate reductions in vascular inflammation and endothelial dysfunction in db/db mice. .
- Brett R Cutler (03/06/2018). Blueberry metabolites reduce cell surface glycosaminoglycans and improve endothelial dysfunction in diabetic human aortic endothelial cells. Int J Cardiol.
- DBharat (12/2017). Blueberry metabolites attenuate lipotoxicity-induced endothelial dysfunction. .
- YQian (09/2017). Metabolites of flavonoid compounds preserve indices of endothelial cell nitric oxide bioavailability under glucotoxic conditions. Nature.
- L Bharath (07/2017). Endothelial cell autophagy maintains shear-stress-induced nitric oxide generation via glycolysis-dependent purinergic signaling to eNOS.
- YLi (07/31/2016).
- Wei Chen (12/2015). Natural Products for the Prevention of Oxidative Stress-Related Diseases: Mechanisms and Strategies.
- L P Bharath (09/2015).
- L Panneerseelan-Bharath (06/2014).
- P Nallasamy (05/2014).
- X Li (05/2014).
- Zhenquan Jia (03/2013).
- Zhenquan Jia (02/2013).
- Pon Velayutham Anandh Babu (06/2012).
- Pon Velayutham Anandh Babu (01/2012).
- Hongwei Si (04/2011).
- Ramalingam Sivakumar (10/2009).
- Pon Velayutham Anandh Babu (04/2008).
- Periasamy Srinivasan (03/2008).
- Ramalingam Sivakumar (01/2008).
- Pon Velayutham Anandh Babu (01/2007).
- Pon Velayutham Anandh Babu (01/2007).
- Pon Velayutham Anandh Babu (06/2006).
- Pon Velayutham Anandh Babu (04/2006).
- Pon Velayutham Anandh Babu (04/2006).
- Pon Velayutham Anandh Babu (02/2006).
Review
- Pari Mokhtari (04/30/2021). Impact of Type 1 Diabetes on the Composition and Functional Potential of Gut Microbiome in Children and Adolescents: Possible Mechanisms, Current Knowledge and Challenges. . [Review]. Gut Microbes.
- BCutler (06/2016). Mechanistic insights in the vascular effects of blueberries: Evidence from recent studies. . [Review].
- Pon Velayutham Anandh Babu (07/2013). [Review].
- Pon Velayutham Anandh Babu (12/2008). [Review].
Book Chapter
- Jae Min Cho (03/15/2021). Procedures to Evaluate the Role of Heparan Sulfate in the Reactivity of Resistance and Conductance Arteries Ex Vivo. Springer.
- Brett Cutler (03/2021). Methods to Analyze the Effect of Diet-Derived Metabolites on Endothelial Inflammation and Cell Surface Glycosaminoglycans. . Springer.
- PVA Babu (08/2016). Sulforaphane and atherosclerosis. . Springer.
- PVABabu (09/2009). Flavonoids and cardiovascular health. . Academic Press.
Other
- Z Jia (01/2018). Natural Products Targeting on Oxidative Stress and Inflammation: Mechanisms, Therapies, and Safety Assessment. Hindawi.