Education History
| Undergraduate |
Utah State University |
BS |
|---|---|---|
| Doctoral Training |
University of Utah |
PhD |
| Postdoctoral Fellowship |
Huntsman Cancer Institute |
Postdoctoral Research Fellow |
| Fellowship |
University of Utah, ARUP Laboratories |
Fellow |
Selected Publications
Journal Article
- Nelson MC, O'Malley LC, Lee SH, Bauer KM, Ghazaryan A, Tang WW, VanSant-Webb C, Tran VB, Hernandez C, Battistone B, Thibeaux A, Round JL, Drummond MJ, Ekiz HA, Evason KJ, Voth WP, O'Connell R (2026). MicroRNA-146a Protects against Hepatocellular Carcinoma through Suppression of CCL5. Cancer Res Commun,
- Battistone B*, Ghazaryan A*, Tang WW*, A'ir ZB, Tantalla J, Thompson J, Bauer KM, Barba C, Nelson M, Tran VTB, O'Malley L, Ngo Q, Hernandez C, Thibeaux A, Ekiz HA, Voth WP, Rao DS, O'Connell RM (2026). T-cell miR-155 regulates the response to tumor-specific mRNA vaccines in a murine model of acute myeloid leukemia. J Immunol,
- Tang WW, Battistone B, Bauer KM, Weis AM, Barba C, Fadlullah MZH, Ghazaryan A, Tran VB, Lee SH, Agir ZB, Nelson MC, Victor ES, Thibeaux A, Hernandez C, Tantalla J, Tan AC, Rao D, Williams M, Drummond MJ, Beswick EJ, Round JL, Ekiz HA, Voth WP, O'Connell R (2025). A microRNA-regulated transcriptional state defines intratumoral CD8(+) T cells that respond to immunotherapy. Cell reports, 44(2), 115301.
- Ghazaryan A, Wallace JA, Tang WW, Barba C, Lee SH, Bauer KM, Nelson MC, Kim CN, Stubben C, Voth WP, Rao DS, O'Connell RM (2023). miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation. Front Genet, 14, 1192799.
- Ren JG, Xing B, Lv K, O'Keefe RA, Wu M, Wang R, Bauer KM, Ghazaryan A, Burslem GM, Zhang J, O'Connell RM, Pillai V, Hexner EO, Philips MR, Tong W (2023). RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. J Clin Invest, 133(12).
- Thompson JW, Hu R, Huffaker TB, Ramstead AG, Ekiz HA, Bauer KM, Tang WW, Ghazaryan A, Round JL, Fujinami RS, O'Connell RM (2023). MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation. J Immunol, 210(7), 926-934.
- Barba C, Ekiz HA, Tang WW, Ghazaryan A, Hansen M, Lee SH, Voth WP, O'Connell RM (2023). Interferon Gamma-Inducible NAMPT in Melanoma Cells Serves as a Mechanism of Resistance to Enhance Tumor Growth. Cancers (Basel), 15(5).
- Ren JG, Xing B, Lv K, O'Keefe RA, Wu M, Wang R, Bauer KM, Ghazaryan A, Burslem GM, Zhang J, O'Connell RM, Pillai V, Hexner EO, Philips MR, Tong (2023). RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. The Journal of clinical investigation, 133(12),
- Bauer KM, Nelson MC, Tang WW, Chiaro TR, Brown DG, Ghazaryan A, Lee SH, Weis AM, Hill JH, Klag KA, Tran VB, Thompson JW, Ramstead AG, Monts JK, Marvin JE, Alexander M, Voth WP, Stephens WZ, Ward DM, Petrey AC, Round JL, O'Connell RM (2022). CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis. JCI Insight, 7(19).
- Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, O'Connell RM, Round JL (2021). Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep, 37(5), 109916.
- Petersen C, Bell R, Klag KA, Lee SH, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, O'Connell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL (2019). T cell-mediated regulation of the microbiota protects against obesity. Science, 365(6451).
- Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL (2019). Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell Host Microbe, 25(2), 285-299.e8.
- Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round J (2019). Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell host & microbe, 25(2), 285-299.e8.
Review
- Blanchard Z*, Brown EA*, Ghazaryan A*, Welm AL (2025). PDX models for functional precision oncology and discovery science. [Review]. Nat Rev Cancer, 25, (3), 153-166.