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Dan J. Kadrmas

Dan J. Kadrmas, PhD

Languages spoken: English

Academic Information

Departments Adjunct - Radiology & Imaging Sciences

Dan Kadrmas, PhD, is a professor in the Department of Radiology and Imaging Sciences at the University of Utah, an investigator in the Huntsman Cancer Institute, and a member of the Experimental Therapeutics Program. Kadrmas is also director of the Quantitative and Functional PET/CT Laboratory.

Kadrmas researches imaging technologies, particularly the use of positron emission technology (PET) imaging to study multiple aspects of tumor physiology, glucose metabolism, blood flow, hypoxia, and growth in various types of cancer.

Kadrmas received a master's degree from the University of Iowa and a PhD from the University of North Carolina, Chapel Hill.

Education History

Undergraduate Gustavus Adolphus College
BA
Graduate Training University of Iowa
MS
Fellowship University of Iowa, Department of Physics
Fellow
Doctoral Training University of North Carolina
PhD
Fellowship University of North Carolina
Fellow
Postdoctoral Fellowship University of Utah School of Medicine, Department of Radiology, Medical Imaging Research Laboratory
Postdoctoral Fellow

Selected Publications

Journal Article

  1. Enslow MS, Zollinger LV, Morton KA, Butterfield RI, Kadrmas DJ, Christian PE, Boucher KM, Heilbrun ME, Jensen RL, Hoffman JM (2012). Comparison of 18F-fluorodeoxyglucose and 18F-fluorothymidine PET in differentiating radiation necrosis from recurrent glioma. Clin Nucl Med, 37(9), 854-61.
  2. Di Bella EV, Ross SG, Kadrmas DJ, Khare HS, Christian PE, McJames S, Gullberg AG (2001). Compartmental modeling of technetium-99m-labeled teboroxime with dynamic single-photon emission computed tomography: comparison with static thallium-201 in a canine model. Invest Radiol, 36(3), 178-85.
  3. Di Bella EV, Kadrmas DJ, Christian PE (2001). Feasibility of dual-isotope coincidence/single-photon imaging of the myocardium. J Nucl Med, 42(6), 944-50.
  4. Kadrmas DJ, Christian PE (2002). Comparative evaluation of lesion detectability for 6 PET imaging platforms using a highly reproducible whole-body phantom with (22)Na lesions and localization ROC analysis. J Nucl Med, 43(11), 1545-54.
  5. Kadrmas DJ, Casey ME, Conti M, Jakoby BW, Lois C, Townsend DW (2009). Impact of time-of-flight on PET tumor detection. J Nucl Med, 50(8), 1315-23.
  6. Lois C, Jakoby BW, Long MJ, Hubner KF, Barker DW, Casey ME, Conti M, Panin VY, Kadrmas DJ, Townsend DW (2010). An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging. J Nucl Med, 51(2), 237-45.
  7. Kadrmas DJ, Oktay M (2013). Generalized separable parameter space techniques for fitting 1K-5K serial compartment models. Medical physics, 40(7), 072502.
  8. Kadrmas DJ, Frey EC, Tsui B (1999). Simultaneous technetium-99m/thallium-201 SPECT imaging with model-based compensation for cross-contaminating effects. Physics in medicine and biology, 44(7), 1843-60.
  9. Kadrmas DJ, DiBella EV, Huesman RH, Gullberg G (1999). Analytical propagation of errors in dynamic SPECT: estimators, degrading factors, bias and noise. Physics in medicine and biology, 44(8), 1997-2014.
  10. Kadrmas DJ, Gullberg G (2001). 4D maximum a posteriori reconstruction in dynamic SPECT using a compartmental model-based prior. Physics in medicine and biology, 46(5), 1553-74.
  11. Rust TC, Kadrmas D (2003). Survey of parallel slat collimator designs for hybrid PET imaging. Physics in medicine and biology, 48(6), N97-104.
  12. Kadrmas D (2004). LOR-OSEM: statistical PET reconstruction from raw line-of-response histograms. Physics in medicine and biology, 49(20), 4731-44.
  13. Rust TC, Kadrmas D (2006). Rapid dual-tracer PTSM+ATSM PET imaging of tumour blood flow and hypoxia: a simulation study. Physics in medicine and biology, 51(1), 61-75.
  14. Rust TC, DiBella EV, McGann CJ, Christian PE, Hoffman JM, Kadrmas D (2006). Rapid dual-injection single-scan 13N-ammonia PET for quantification of rest and stress myocardial blood flows. Physics in medicine and biology, 51(20), 5347-62.
  15. Black NF, McJames S, Rust TC, Kadrmas D (2008). Evaluation of rapid dual-tracer (62)Cu-PTSM + (62)Cu-ATSM PET in dogs with spontaneously occurring tumors. Physics in medicine and biology, 53(1), 217-32.
  16. Zeng GL, Gullberg GT, Kadrmas D (2010). Closed-form kinetic parameter estimation solution to the truncated data problem. Physics in medicine and biology, 55(24), 7453-68.
  17. Zeng GL, Hernandez A, Kadrmas DJ, Gullberg G (2012). Kinetic parameter estimation using a closed-form expression via integration by parts. Physics in medicine and biology, 57(18), 5809-21.
  18. Kadrmas DJ, Rust TC, Hoffman J (2013). Single-scan dual-tracer FLT+FDG PET tumor characterization. Physics in medicine and biology, 58(3), 429-49.
  19. S Ashrafinia, H Mohy-ud-Din, NA Karakatsanis, AK Jha, ME Casey, DJ Kadrmas, and A Rahmi (2017). Generalized PSF Modeling for Optimized Quantitation in PET Imaging. Physics in medicine and biology, 62(12), 5149-5179.
  20. Ashrafinia S, Mohy-Ud-Din H, Karakatsanis NA, Jha AK, Casey ME, Kadrmas DJ, Rahmim (2017). Generalized PSF modeling for optimized quantitation in PET imaging. Physics in medicine and biology, 62(12), 5149-5179.
  21. Kadrmas D (2008). Rotate-and-slant projector for fast LOR-based fully-3-D iterative PET reconstruction. IEEE transactions on medical imaging, 27(8), 1071-83.
  22. Kadrmas DJ, Casey ME, Black NF, Hamill JJ, Panin VY, Conti (2009). Experimental comparison of lesion detectability for four fully-3D PET reconstruction schemes. IEEE transactions on medical imaging, 28(4), 523-34.
  23. Morey AM, Kadrmas D (2013). Effect of varying number of OSEM subsets on PET lesion detectability. Journal of nuclear medicine technology, 41(4), 268-73.
  24. Pack NA, DiBella EV, Rust TC, Kadrmas DJ, McGann CJ, Butterfield R, Christian PE, Hoffman J (2008). Estimating myocardial perfusion from dynamic contrast-enhanced CMR with a model-independent deconvolution method. Journal of cardiovascular magnetic resonance, 10, 52.
  25. Black NF, McJames S, Kadrmas D (2009). Rapid Multi-Tracer PET Tumor Imaging With F-FDG and Secondary Shorter-Lived Tracers. IEEE transactions on nuclear science, 56(5), 2750-2758.
  26. Kadrmas DJ, Di Bella EV, Khare HS, Christian PE, Gullberg G (2000). Static Versus Dynamic Teboroxime Myocardial Perfusion SPECT in Canines. IEEE transactions on nuclear science, 47(3), 1112-1117.
  27. Di Bella EV, Khare HS, Kadrmas DJ, Gullberg G (2000). SPECT Imaging of Teboroxime during Myocardial Blood Flow Changes. IEEE transactions on nuclear science, 47(3), nihpa165910.
  28. Khare HS, Dibella EV, Kadrmas DJ, Christian PE, Gullberg G (2001). Comparison of Static and Dynamic Cardiac Perfusion Thallium-201 SPECT. IEEE transactions on nuclear science, 48(3), 774.
  29. Kadrmas DJ, Oktay MB, Casey ME, Hamill J (2012). Effect of Scan Time on Oncologic Lesion Detection in Whole-Body PET. IEEE transactions on nuclear science, 59(5), 1940-1947.
  30. Bai C, Zeng GL, Kadrmas DJ, Gullberg G (1999). A Study of Apparent Apical Defects in Attenuation Corrected Cardiac SPECT. IEEE transactions on nuclear science, 46(6), 2104-10.
  31. Kadrmas DJ, Rust T (2003). Converging Slat Collimators for PET Imaging with Large-Area Detectors. IEEE transactions on nuclear science, 50(1), 17-23.
  32. Kadrmas DJ, Rust T (2005). Feasibility of Rapid Multi-Tracer PET Tumor Imaging. IEEE transactions on nuclear science, 52(5), 1341-47.
  33. Hichwa RH, Kadrmas DJ, Watkins GL, Wollenweber SD, Maniam S, Boles Ponto LL, Richmond JCW, Koeppel J (1995). Vanadium-48: A Renewable Source for Transmission Scanning with PET. Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 99, 804-6.
  34. Zeng GL, Kadrmas DJ, Gullberg G (2012). Fourier domain closed-form formulas for estimation of kinetic parameters in reversible multi-compartment models. Biomedical engineering online, 11, 70.

Abstract

  1. Kadrmas DJ, Frey EC, Tsui BM (1998). Evaluation of Bias and Noise Properties for Fast Iterative Reconstruction-Based Scatter Compensation. Journal of nuclear medicine, 39(5), 177P.
  2. Kadrmas DJ, Frey EC, Ziffer JA, Tsui BM (1997). Iterative Reconstruction of Simultaneously Acquired Tc-99m Sestamibi / Tl-201 Cardiac SPECT Data with Compensation for Cross-Contaminating Effects. Journal of nuclear medicine, 38(5), 88P.
  3. Kadrmas DJ, Frey EC, Tsui BM (1997). Effects of Improving Energy Resolution upon the Performance of Scatter Compensation Techniques in SPECT. Journal of nuclear medicine, 38(5), 89P..
  4. Kadrmas DJ, Frey EC, Tsui BM (1995). Improved Signal-to-Noise Ratio in SPECT Images by Simultaneous Reconstruction from Multiple Overlapping Energy Windows. Journal of nuclear medicine, 36(5), 29P.
  5. Jang S, Jaszczak RJ, Kadrmas DJ, Greer KL, Coleman R (1995). Effect of Breast Attenuation on Defect Size Measurement in Myocardial SPECT Imaging,. Journal of nuclear medicine, 36(5), 40P.