Dr. Dan Kaufmann is a Research Assistant Professor at the University of Utah’s Department of Medicine, Division of Rheumatology. With a Ph.D. in Medicinal Chemistry and Pharmaceutics from the University of Jerusalem, Dr. Kaufmann has made significant contributions to drug design and synthesis, including the development of SPD, a novel anticonvulsant and migraine preventive compound. This patented compound has demonstrated great promise in pre-clinical models for epilepsy, neuropathic pain, and migraine.
In recent years, Dr. Kaufmann’s research has focused on the modulation of migraine by sex, stress, and affect. He has broadened his scope to include musculoskeletal pain and fatigue. His current work within the Division of Rheumatology explores the intersection of psychological treatments and rheumatic diseases, reflecting his growing interest in the emotional aspects of chronic pain.
Driven by a desire to integrate both pharmacological and psychological approaches to pain management, Dr. Kaufmann is on track to become a licensed Clinical Mental Health Counselor. He trained extensively in cognitive behavioral hypnotherapy, neurolinguistic programming (NLP), biofeedback, autogenic training, the Unified Protocol, and Emotional Awareness and Expression Therapy (EAET).
Currently, Dr. Kaufmann is evaluating the effects of EAET on migraine endpoints and is investigating the crucial role of trauma in the emotional experiences of migraine sufferers. His long-term goal is to combine his expertise in pharmacology, physiology, and behavior to develop innovative treatments for various pain conditions, including migraine and rheumatology-related pain, ultimately improving the lives of patients dealing with these complex diseases.
Education History
| Fellowship |
University of Utah |
Postdoctoral Research Associate |
|---|---|---|
|
University of Utah |
Postdoctoral Research Fellow | |
| Research Fellow |
University of Utah |
Postdoctoral Research Fellow |
|
Hebrew University of Jerusalem School of Pharmacy |
PhD | |
| Undergraduate |
Hebrew University of Jerusalem |
BSc |
Selected Publications
Journal Article
- Kaufmann D, Brennan KC (2018). The Effects of Chronic Stress on Migraine Relevant Phenotypes in Male Mice. Front Cell Neurosci, 12, 294. (Read full article)
- Xie Y, Kaufmann D, Moulton MJ, Panahi S, Gaynes JA, Watters HN, Zhou D, Xue HH, Fung CM, Levine EM, Letsou A, Brennan KC, Dorsky RI (2017). Lef1-dependent hypothalamic neurogenesis inhibits anxiety. PLoS Biol, 15(8), e2002257. (Read full article)
- Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC (2015). sec-Butylpropylacetamide (SPD) has antimigraine properties. Cephalalgia, 36(10), 924-35. (Read full article)