Academic Information
Departments Primary - Biochemistry
Education History
| Postdoctoral Training |
Yale University |
Postdoctoral Training |
|---|---|---|
| Doctoral Training |
Medical Research Council, Human Genetics Unit and Open University |
PhD |
| Graduate Training |
University of Buenos Aires |
MSc |
Selected Publications
Journal Article
- Gorbea C, Elhakiem A, Cazalla D (2022). Allosteric regulation of noncoding RNA function by microRNAs. Nucleic Acids Res, 50(11), 6511-6520. (Read full article)
- Cazalla D (2021). Learning noncoding RNA biology from viruses. Mamm Genome, 33, 412-420. (Read full article)
- Gorbea C, Mosbruger T, Nix DA, Cazalla D (2019). Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing. Elife, 8. (Read full article)
- DePaula-Silva AB, Gorbea C, Doty DJ, Libbey JE, Sanchez JMS, Hanak TJ, Cazalla D, Fujinami RS (2019). Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation. J Neuroinflammation, 16(1), 152. (Read full article)
- Cazalla D (2018). Novel roles for Sm-class RNAs in the regulation of gene expression. RNA Biol, Jul 9:1-7.
- Gorbea C, Mosbruger T, Cazalla D (2017). A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis. Nature, 550(7675), 275-279. (Read full article)
- Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trmbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo D (2014). MicroRNA-9 controls dendritic development by targeting REST. Elife, 3. (Read full article)
- Maurin T, Cazalla D, Yang S Jr, Bortolamiol-Becet D, Lai EC (2012). RNase III-independent microRNA biogenesis in mammalian cells. RNA, 18(12), 2166-73. (Read full article)
- Cazalla D, Xie M, Steitz JA (2011). A primate herpesvirus uses the integrator complex to generate viral microRNAs. Mol Cell, 43(6), 982-92. (Read full article)
Review
- Gorbea C, Elhakiem A, Cazalla D (2022). Shaping the host cell environment with viral noncoding RNAs. [Review]. Semin Cell Dev Biol, 146, 20-30. (Read full article)
- Steitz J, Borah S, Cazalla D, Fok V, Lytle R, Mitton-Fry R, Riley K, Samji T (2011). Noncoding RNPs of viral origin.LID - 10.1101/cshperspect.a005165 [doi]LID - a005165 [pii]. [Review]. Cold Spring Harb Perspect Biol, 3(3). (Read full article)