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Demián Cazalla

Demián Cazalla, PhD

Languages spoken: English, Spanish

Academic Information

Departments Primary - Biochemistry

Education History

Graduate Training University of Buenos Aires
MSc
Doctoral Training Medical Research Council, Human Genetics Unit and Open University
PhD
Postdoctoral Training Yale University
Postdoctoral Training

Selected Publications

Journal Article

  1. Cazalla (2021). Learning noncoding RNA biology from viruses. Mammalian genome, 33, 412-420. (Read full article)
  2. Gorbea C, Mosbruger T, Cazalla (2017). A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis. Nature, 550(7675), 275-279. (Read full article)
  3. Maurin T, Cazalla D, Yang S Jr, Bortolamiol-Becet D, Lai E (2012). RNase III-independent microRNA biogenesis in mammalian cells. RNA (New York, N.Y.), 18(12), 2166-73. (Read full article)
  4. Cazalla D, Xie M, Steitz J (2011). A primate herpesvirus uses the integrator complex to generate viral microRNAs. Molecular cell, 43(6), 982-92. (Read full article)
  5. DePaula-Silva AB, Gorbea C, Doty DJ, Libbey JE, Sanchez JMS, Hanak TJ, Cazalla D, Fujinami R (2019). Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation. Journal of neuroinflammation, 16(1), 152. (Read full article)
  6. Cazalla (2018). Novel roles for Sm-class RNAs in the regulation of gene expression. RNA biology, Jul 9:1-7.
  7. Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trümbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo (2014). MicroRNA-9 controls dendritic development by targeting REST. eLife, 3, (Read full article)
  8. Gorbea C, Mosbruger T, Nix DA, Cazalla (2019). Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing. eLife, 8, (Read full article)
  9. Gorbea C, Elhakiem A, Cazalla (2022). Allosteric regulation of noncoding RNA function by microRNAs. Nucleic acids research, 50(11), 6511-6520. (Read full article)

Review

  1. Steitz J, Borah S, Cazalla D, Fok V, Lytle R, Mitton-Fry R, Riley K, Samji (2011). Noncoding RNPs of viral origin.LID - 10.1101/cshperspect.a005165 [doi]LID - a005165 [pii]. Cold Spring Harbor perspectives in biology, 3(3), (Read full article)
  2. Gorbea C, Elhakiem A, Cazalla (2023). Shaping the host cell environment with viral noncoding RNAs. Seminars in cell & developmental biology, 146, 20-30. (Read full article)