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Guillaume L. Hoareau

Guillaume L. Hoareau, PhD, DVM

Languages spoken: English, French, Spanish

Academic Information

Departments Primary - Eccles Health Library

Academic Office Information

Board Certification

  • American College of Veterinary Emergency Critical Care
  • European College of Veterinary Emergency and Critical Care

Research Interests

  • Mitochondria
  • Translational Research
  • Acute Trauma Resuscitation

Dr. Hoareau is a veterinarian with board certification in Emergency and Critical Care and a Ph.D. in Integrative Pathobiology. His research focuses on acute care translational research with an interest in military resuscitation. Specifically, he studies novel therapeutic approaches to mitigate ischemia-reperfusion injury in hemorrhagic shock. He works toward preserving mitochondrial function, the essential cell machinery for energy production. He seeks to accelerate the transition of new therapies to clinical practice. Dr. Hoareau mentors trainees around all aspects of translational acute care research with a strong interest and commitment to diversity, equity, and inclusion. He is part of several pipelines for trainees from underrepresented minorities.

Education History

Research Fellow Travis Air Force Base/Oak Ridge Institute for Science and Education
Postdoctoral Research Fellow
Travis Air Force Base/Henry M. Jackson Foundation for the Advancement of Military Medicine
Postdoctoral Fellow
Doctoral Training University of California, Davis
University of California, Davis/William R. Pritchard Veterinary Medical Teaching Hospital
Internship University of Pennsylvania School of Veterinary Medicine/Matthew J. Ryan Hospital
National Veterinary School of Toulouse
Undergraduate Levavasseur
BSc (Hons)

Selected Publications

Journal Article

  1. Huther A, Edwards TH, Jaramillo EL, Giles JT 3rd, Israel SK, Mison M, Ambrosius L, Kaiser T, Hoareau GL (2024). The use of a kaolin-based hemostatic dressing to attenuate bleeding in dogs: A series of 4 cases. J Vet Emerg Crit Care (San Antonio). (Read full article)
  2. Silverton NA, Lofgren LR, Kuck K, Stoddard GJ, Johnson R, Ramezani A, Hoareau GL (2024). Near-infrared spectroscopy for kidney oxygen monitoring in a porcine model of hemorrhagic shock, hemodilution, and REBOA. Sci Rep, 14(1), 2646. (Read full article)
  3. Haugland H, Gamberini L, Hoareau GL, Haenggi M, Greif R, Brede JR, REBOA OHCA expert panel and other Collaborators (2023). Resuscitative endovascular balloon occlusion of the aorta in out-of-hospital cardiac arrest - A Delphi consensus study for uniform data collection. Resusc Plus, 16, 100485. (Read full article)
  4. Hirahara AM, Khan MS, Ishidoya Y, Smego D, Roman O, Ranjan R, Krueger L, Hoareau G, Selzman CH, Dosdall DJ (2023). Canine Model of Ischemia-Induced Ventricular Tachycardia. J Surg Res, 293, 196-203. (Read full article)
  5. Krulewitz N, Levin NM, Youngquist S, Kelly C, Hoareau G, Johnson MA, Ockerse P (2023). Evaluation of esophageal injuries after defibrillation with transesophageal ultrasound probe in the mid-esophagus in pigs. Am J Emerg Med, 74, 14-16. (Read full article)
  6. Hilgart DR, Iversen MM, Peters AY, Zabriskie MS, Hoareau GL, Vapniarsky N, Clark GA, Shah LM, Rieke V (2023). Non-invasive central nervous system assessment of a porcine model of neuropathic pain demonstrates increased latency of somatosensory-evoked potentials. J Neurosci Methods, 396, 109934. (Read full article)
  7. Khan MS, Smego D, Ishidoya Y, Hirahara AM, Offei E, Ruiz Castillo MS, Gharbia O, Li H, Palatinus JA, Krueger L, Hong T, Hoareau GL, Ranjan R, Selzman CH, Shaw RM, Dosdall DJ (2023). A canine model of chronic ischemic heart failure. Am J Physiol Heart Circ Physiol, 324(6), H751-H761. (Read full article)
  8. Patel N, Johnson MA, Vapniarsky N, Van Brocklin MW, Williams TK, Youngquist ST, Ford R, Ewer N, Neff LP, Hoareau GL (2023). Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock. Sci Rep, 13(1), 4496. (Read full article)
  9. Alexander MD, Hoareau G, Zabriskie MS, Palatinus H, Chakravarthula NR, Wang C, Johnson MA (2023). Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke. J Vis Exp, (192). (Read full article)
  10. Patel NTP, Gaffley M, Leblanc MJR, Lane MR, Hoareau GL, Johnson MA, Jordan JE, Neff LP, Williams TK (2022). Endovascular Perfusion Augmentation After Resuscitative Endovascular Balloon Occlusion of the Aorta Improves Renal Perfusion and Decreases Vasopressors. J Surg Res, 279, 712-721. (Read full article)
  11. Lofgren LR, Hoareau GL, Kuck K, Silverton NA (2022). Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock. J Vis Exp, (188). (Read full article)
  12. Wheeler LR, Edwards TH, Heinz JA, Scott LLF, Grantham LE 2nd, Keesee JD, Henderson AF, Gerardo AC, Hoareau G, Bynum JA (2022). Comparison of assessment of coagulation in healthy dogs by the TEG 6s and TEG 5000 viscoelastic analyzers. J Vet Diagn Invest, 34(5), 780-788. (Read full article)
  13. Hoareau GL, Beyer CA, Caples CM, Spruce MW, Gilbert Z, Grayson JK, Neff LP, Williams TK, Johnson MA (2020). Esmolol reduces myocardial injury induced by resuscitative endovascular balloon occlusion of the aorta (REBOA) in a porcine model of hemorrhagic shock. Injury, 51(10), 2165-2171. (Read full article)
  14. Abid M, Neff LP, Russo RM, Hoareau G, Williams TK, Grayson JK, DuBose JJ, Lendrum R, Johnson MA (2020). Reperfusion repercussions: A review of the metabolic derangements following resuscitative endovascular balloon occlusion of the aorta. J Trauma Acute Care Surg, 89(2S Suppl 2), S39-S44. (Read full article)
  15. Beyer CA, Burmeister DM, Gmez BI, Tercero J, Babcock E, Walker LE, Hoareau G, Sosnov J, Chung KK, Stewart IJ (2019). Point-of-Care Urinary Biomarker Testing for Risk Prediction in Critically Injured Combat Casualties. J Am Coll Surg, 229(5), 508-515.e1. (Read full article)
  16. Tibbits EM, Hoareau GL, Simon MA, Davidson AJ, DeSoucy ES, Faulconer ER, DuBose JJ, Neff LP, Grayson JK, Williams TK, Johnson MA (2018 Jul). Location is everything: The hemodynamic effects of REBOA in Zone 1 versus Zone 3 of the aorta. J Trauma Acute Care Surg, 85(1), 101-107. (Read full article)


  1. Youngquist ST, Tonna JE, Bartos JA, Johnson MA, Hoareau GL, Hutin A, Lamhaut L (2020). Current Work in Extracorporeal Cardiopulmonary Resuscitation. [Review]. Crit Care Clin, 36(4), 723-735. (Read full article)


  1. Johnson MA, Hoareau G, Williams TK, Neff LP (2020). Letter to the editor: Response to letter from Dr. Martin et al: Not ready for prime time: Intermittent versus partial REBOA for prolonged hemorrhage control in a highly lethal porcine injury model. [Letter to the editor]. J Trauma Acute Care Surg, 88(6), e150-e151. (Read full article)


  1. Hoareau GL, Beyer CA, Kashtan HW, Walker LE, Wilson C, Wishy A, Grayson JK, Stewart IJ (2020). Improvised Field Expedient Method for Renal Replacement Therapy in a Porcine Model of Acute Kidney Injury. Disaster Med Public Health Prep (15(6), pp. 741-749). United States. (Read full article)
  2. Hoareau GL, Beyer CA, Caples CA, Spruce MW, Kevin Grayson J, Neff LP, Williams TK, Johnson MA (2020). Automated Partial Versus Complete Resuscitative Endovascular Balloon Occlusion of the Aorta for the Management of Hemorrhagic Shock in a Pig Model of Polytrauma: a Randomized Controlled Pilot Study. Mil Med (185(11-12), pp. e1923-e1930). England. (Read full article)
  3. Beyer CA, Hoareau GL, Kashtan HW, Wishy AM, Caples C, Spruce M, Grayson JK, Neff LP, Williams TK, Johnson MA (2019). Resuscitative endovascular balloon occlusion of the aorta (REBOA) in a swine model of hemorrhagic shock and blunt thoracic injury. Eur J Trauma Emerg Surg (46(6), pp. 1357-1366). Germany. (Read full article)