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Harry R. Hill

Harry R. Hill, MD

Languages spoken: English

Academic Information

Departments Emeritus - Pathology , Emeritus - Pediatrics


Academic Office Information

Board Certification

  • American Board of Pathology (Anatomic & Clinical)
  • American Board of Pediatrics (Pediatrics)

Harry R. Hill, M.D. is a Professor of Pathology, Pediatrics, and Medicine, who trained in Immunology, Infectious Diseases and Clinical Laboratory Medicine at the University of Washington in Seattle and at the University of Minnesota in Minneapolis before coming to the University of Utah. Approximately 40 years ago, he established a Clinical Immunology Clinic to see primary immunodeficiency diseases such as hypogammaglobulinemia, chronic granulomatous disease, Job syndrome of Hyper IgE and recurrent infections, Wiskott Aldridge disease, the Hyper igM syndrome, isolated IgA deficiency, IgG subclass deficiencies and other disorders associate with recurrent and often severe infections. He also established a laboratory to evaluate the immunologic function in these patients, which is now a major laboratory at ARUP Laboratories, the national esoteric reference laboratory owned by the University of Utah. More recently, Dr. Hill, along with several colleagues at ARUP Laboratories, has begun to develop rapid molecular tests for some of these disorders that can be accomplished as rapidly as in 1-2 days and to use state of the art new tools such as next generation sequencing to find new causes of these primary immunodeficiencies, which can have onset from the newborn period until mid to late adulthood. Appointments can be made through the Administrative Assistant for the Division, Jeannette Rejali at 801-581-5873. The Clinical Immunology Clinic meets in Clinic 1A, which is labeled the Infectious Disease Clinic on Thursday mornings. Referral forms requesting critical clinical and laboratory data will be sent to the primary care doctor or referring specialist to speed up the workup and prevent duplication of testing. Dr. Adi Gundlapalli, is an associate of Dr. Hill's trained in immunolgy and infectious diseases, who also sees immunodeficient patients and covers for Dr. Hill when he is away. Dr. Hill has been listed in the Best Doctors in America from 1996 through 2015; he has also been funded as a researcher for 40 years from the National institutes of Health. He takes pride in spending as long as necessay deciphering the complex patients seen in this clinic. Additional benefits from evaluation in this clinic may be a better understanding of the risks of offspring and relatives developing similiar disorders.

Education History

Chief Resident University of Washington and Harborview Medical Center
Chief Resident
University of Minnesota Hospitals
Fellowship University of Washington
University of Washington School of Medicine
Internship Emory University, Grady Memorial Hospital
Baylor College of Medicine
Undergraduate Louisiana State University

Selected Publications

Journal Article

  1. Eckman E, Laman JD, Fischer KF, Lopansri B, Martins TB, Hill HR, Kriesel JD (2021). Spinal fluid IgG antibodies from patients with demyelinating diseases bind multiple sclerosis-associated bacteria. J Mol Med (Berl), 99(10), 1399-1411.
  2. Joshi HR, Hill HR, Asch J, Margraf RL, Coonrod E, Durtschi J, Zhou Q, He X, Voelkerding KV, Kumnovics A (2020). CXXC5 variant in an immunodeficient patient with a progressive loss of hematopoietic cells. J Allergy Clin Immunol, 147(4), 1504-1507.e8.
  3. Liu BM, Hill HR (2021). Role of Host Immune and Inflammatory Responses in COVID-19 Cases with Underlying Primary Immunodeficiency: A Review. J Interferon Cytokine Res, 40(12), 549-554.
  4. Joshi HR, Hill HR, Zhou Z, He X, Voelkerding KV, Kumnovics A (2020). Frontline Science: Cxxc5 expression alters cell cycle and myeloid differentiation of mouse hematopoietic stem and progenitor cells. J Leukoc Biol, 108(2), 469-484.
  5. Hill HR (2019). Fitness genes of group A streptococci in necrotizing fasciitis and myositis. J Clin Invest, 129(2), 516-517.
  6. Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS, Kanariou MG, Lycopoulou L, Tzanoudaki M, Sleasman JW, Parikh S, Pinero G, Fischer BM, Dbaibo G, Unal E, Patiroglu T, Karakukcu M, Al-Saad KK, Dilley MA, Pai SY, Dutmer CM, Gelfand EW, Geier CB, Eibl MM, Wolf HM, Henderson LA, Hazen MM, Bonfim C, Wolska-Kunierz B, Butte MJ, Hernandez JD, Nicholas SK, Stepensky P, Chandrakasan S, Miano M, Westermann-Clark E, Goda V, Krivn G, Holland SM, Fadugba O, Henrickson SE, Ozen A, Karakoc-Aydiner E, Baris S, Kiykim A, Bredius R, Hoeger B, Boztug K, Pashchenko O, Neven B, Moshous D, Villartay JP, Bousfiha AA, Hill HR, Notarangelo LD, Walter JE (2019). Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. J Allergy Clin Immunol Pract, 7(6), 1970-1985.e4.
  7. Yang KD, Hill HR (1996). Immune responses to infectious diseases: an evolutionary perspective. Pediatr Infect Dis J, 15(4), 355-64.
  8. Anthony BF, Hill HR (1988). Gram-positive bacteria: an overview and summary of session. Rev Infect Dis, 10 Suppl 2, S345-50.
  9. Fischer SH, Ochs HD, Wedgwood RJ, Skvaril F, Morell A, Hill HR, Schiffmann G, Corey L (1988). Survival of antigen-specific antibody following administration of intravenous immunoglobulin in patients with primary immunodeficiency diseases. Monogr Allergy, 23, 225-35.
  10. Kaplan EL, Hill HR (1987). Return of rheumatic fever: consequences, implications, and needs. J Pediatr, 111(2), 244-6.
  11. Hill HR, Meier FA (1986). Host defense factors in the gastrointestinal tract. Pediatr Infect Dis, 5(1 Suppl), S144-7.
  12. Hill HR (1985). Host defenses in the neonate: prospects for enhancement. Semin Perinatol, 9(1), 2-11.
  13. Hill HR, Matsen JM (1983). Enzyme-linked immunosorbent assay and radioimmunoassay in the serologic diagnosis of infectious diseases. J Infect Dis, 147(2), 258-63.
  14. Hill HR, Patriarca P (1982). Round table on the clinical application of leucocyte function tests. Adv Exp Med Biol, 141, 659-82.
  15. Hill HR (1981). Immunodeficiency diseases. Prog Clin Pathol, 8, 205-38.
  16. Hill HR (1977). Evaluating the patient with recurrent infections. South Med J, 70(2), 230-5.
  17. Pirtle EC, Hill HR, Swanson MR, van Deusen RA (1976). Haemagglutination-inhibiting antibodies against swine influenza and Hong Kong influenza viruses in swine sera in the USA. Bull World Health Organ, 53(1), 7-11.
  18. Hill HR, Riter ME, Menge SK, Johnson DR, Matsen JM (1975). Rapid identification of group B streptococci by counterimmunoelectrophoresis. J Clin Microbiol, 1(2), 188-91.
  19. Hill HR, Matsen JM (1973). Newer antibiotic agents acting on gram-negative organisms. Geriatrics, 28(8), 72-6.


  1. Hill HR (1988). Intensive control measures for streptococcal infections--is there a need? West J Med, 148(5), 575-6.
  2. Hill HR (1979). Immunity in diabetes mellitus: impaired or enhanced? West J Med, 130(6), 547-50.