Markus Amann

Markus Amann, PhD, MS

Languages spoken: English, German, Latin

Academic Information

Departments Adjunct - Internal Medicine , Primary - Anesthesiology

Divisions: Geriatrics

Lab

Dr. Amann is a Professor of Anesthesiology, Theodore H. Stanley Presidential Endowed Chair in Anesthesiology, and Adjunct Professor in the Departments of Internal Medicine and Biomedical Engineering. His research focuses on the neural control of the circulation and breathing, and the etiology of central nervous system fatigue. Dr. Amann’s work aims at enhancing our understanding of the impact of cardiovascular disease on autonomic reflex function and of mechanisms determining neuromuscular fatigue during physical activity. More information about Dr. Amann's research can be found at the Utah Vascular Research Laboratory.

Education History

Graduate Training Technical University of Munich
 MS
Doctoral Training University of Utah
 PhD
Postdoctoral Fellowship University of Wisconsin
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. Lossnitzer D, Amann M, Zugck C, Katus H, Bärtsch P, Weiss (2008). Exercise-induced hemostatic activation in patients with dilated cardiomyopathy in sinus rhythm. Blood coagulation & fibrinolysis, 19(2), 146-52. (Read full article)
  2. Hilty L, Lutz K, Maurer K, Rodenkirch T, Spengler CM, Boutellier U, Jancke L, Amann (2011). Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans. Experimental physiology, 96(5), 505-17. (Read full article)
  3. Ives SJ, Andtbacka RH, Noyes RD, McDaniel J, Amann M, Witman MA, Symons JD, Wray DW, Richardson R (2011). Human skeletal muscle feed arteries studied in vitro: the effect of temperature on alpha(1)-adrenergic responsiveness. Experimental physiology, 96(9), 907-18. (Read full article)
  4. Pollak KA, Swenson JD, Vanhaitsma TA, Hughen RW, Jo D, White AT, Light KC, Schweinhardt P, Amann M, Light A (2014). Exogenously applied muscle metabolites synergistically evoke sensations of muscle fatigue and pain in human subjects. Experimental physiology, 99(2), 368-80. (Read full article)
  5. Girard O, Amann M, Aughey R, Billaut F, Bishop DJ, Bourdon P, Buchheit M, Chapman R, D'Hooghe M, Garvican-Lewis LA, Gore CJ, Millet GP, Roach GD, Sargent C, Saunders PU, Schmidt W, Schumacher Y (2013). Position statement--altitude training for improving team-sport players' performance: current knowledge and unresolved issues. British journal of sports medicine, 47 Suppl 1, i8-16. (Read full article)
  6. Amann (2012). Significance of Group III and IV muscle afferents for the endurance exercising human. Clinical and experimental pharmacology & physiology, 39(9), 831-5. (Read full article)
  7. Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston T, Le Fur Y, Jeong EK, Amann M, Richardson RS, Trinity JD, Wang E, Layec (2018). Maximal strength training increases muscle force generating capacity and the anaerobic ATP synthesis flux without altering the cost of contraction in elderly. Experimental gerontology, 111, 154-161. (Read full article)
  8. Sidhu SK, Weavil JC, Rossman MJ, Jessop JE, Bledsoe AD, Buys MJ, Supiano MS, Richardson RS, Amann (2019). Exercise Pressor Reflex Contributes to the Cardiovascular Abnormalities Characterizing: Hypertensive Humans During Exercise. Hypertension (Dallas, Tex., 74(6), 1468-1475. (Read full article)
  9. Amann M, Venturelli M, Ives SJ, Morgan DE, Gmelch B, Witman MA, Jonathan Groot H, Walter Wray D, Stehlik J, Richardson R (2014). Group III/IV muscle afferents impair limb blood in patients with chronic heart failure. International journal of cardiology, 174(2), 368-75. (Read full article)
  10. Hochholzer W, Valina CM, Stratz C, Amann M, Schlittenhardt D, Büttner HJ, Trenk D, Neumann F (2014). High-sensitivity cardiac troponin for risk prediction in patients with and without coronary heart disease. International journal of cardiology, 176(2), 444-9. (Read full article)
  11. Amann M, Romer LM, Pegelow DF, Jacques AJ, Hess CJ, Dempsey J (2006). Effects of arterial oxygen content on peripheral locomotor muscle fatigue. Journal of applied physiology (Bethesda, Md., 101(1), 119-27. (Read full article)
  12. Amann M, Proctor LT, Sebranek JJ, Eldridge MW, Pegelow DF, Dempsey J (2008). Somatosensory feedback from the limbs exerts inhibitory influences on central neural drive during whole body endurance exercise. Journal of applied physiology (Bethesda, Md., 105(6), 1714-24. (Read full article)
  13. Amann M, Venturelli M, Ives SJ, McDaniel J, Layec G, Rossman MJ, Richardson R (2013). Peripheral fatigue limits endurance exercise via a sensory feedback-mediated reduction in spinal motoneuronal output. Journal of applied physiology (Bethesda, Md., 115(3), 355-64. (Read full article)
  14. Amann M, Goodall S, Twomey R, Subudhi AW, Lovering AT, Roach R (2013). AltitudeOmics: on the consequences of high-altitude acclimatization for the development of fatigue during locomotor exercise in humans. Journal of applied physiology (Bethesda, Md., 115(5), 634-42. (Read full article)
  15. Broxterman RM, Layec G, Hureau TJ, Amann M, Richardson R (2017). Skeletal muscle bioenergetics during all-out exercise: mechanistic insight into the oxygen uptake slow component and neuromuscular fatigue. Journal of applied physiology (Bethesda, Md., 122(5), 1208-1217. (Read full article)
  16. Amann M, Blain G, Proctor L, Sebranek JJ, Pegelow DF, Dempsey J (2010). Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. Journal of applied physiology (Bethesda, Md., 109, 966-976.
  17. Amann M, Dempsey J (2012). Group III and IV muscle afferents contribute to the ventilatory response to exercise. Journal of applied physiology (Bethesda, Md., 110, 863-900.
  18. Hureau TJ, Weavil JC, Thurston TS, Wan HY, Gifford JR, Jessop JE, Buys MJ, Richardson RS, Amann (2019). Pharmacological attenuation of group III/IV muscle afferents improves endurance performance when oxygen delivery to locomotor muscles is preserved. Journal of applied physiology (Bethesda, Md., 127(5), 1257-1266. (Read full article)
  19. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Bledsoe AD, Jessop JE, Buys MJ, Richardson RS, Amann (2020). The muscle reflex and chemoreflex interaction: ventilatory implications for the exercising human. Journal of applied physiology (Bethesda, Md., 129(4), 691-700. (Read full article)
  20. Lovering AT, Stickland MK, Amann M, O'Brien MJ, Hokanson JS, Eldridge M (2011). Effect of a patent foramen ovale on pulmonary gas exchange efficiency at rest and during exercise. Journal of applied physiology (Bethesda, Md., 110(5), 1354-61. (Read full article)
  21. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey J (2010). Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. Journal of applied physiology (Bethesda, Md., 109(4), 966-76. (Read full article)
  22. Hureau TJ, Weavil JC, Sidhu SK, Thurston TS, Reese VR, Zhao J, Nelson AD, Birgenheier NM, Richardson RS, Amann (2021). Ascorbate attenuates cycling exercise-induced neuromuscular fatigue but fails to improve exertional dyspnea and exercise tolerance in COPD. Journal of applied physiology (Bethesda, Md., 130(1), 69-79. (Read full article)
  23. Venturelli M, Amann M, Trinity JD, Ives SJ, Richardson R (2021). Spinal cord injury and vascular function: evidence from diameter-matched vessels. Journal of applied physiology (Bethesda, Md., 130(3), 562-570. (Read full article)
  24. Weavil JC, Sidhu SK, Mangum TS, Richardson RS, Amann (2016). Fatigue diminishes motoneuronal excitability during cycling exercise. Journal of neurophysiology, 116(4), 1743-1751. (Read full article)
  25. Amann M, Eldridge MW, Lovering AT, Stickland MK, Pegelow DF, Dempsey J (2006). Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humans. The Journal of physiology, 575(Pt 3), 937-52. (Read full article)
  26. Amann M, Romer LM, Subudhi AW, Pegelow DF, Dempsey J (2007). Severity of arterial hypoxaemia affects the relative contributions of peripheral muscle fatigue to exercise performance in healthy humans. The Journal of physiology, 581(Pt 1), 389-403. (Read full article)
  27. Lovering AT, Stickland MK, Amann M, Murphy JC, O'Brien MJ, Hokanson JS, Eldridge M (2008). Hyperoxia prevents exercise-induced intrapulmonary arteriovenous shunt in healthy humans. The Journal of physiology, 586(18), 4559-65. (Read full article)
  28. Amann M, Runnels S, Morgan DE, Trinity JD, Fjeldstad AS, Wray DW, Reese VR, Richardson R (2011). On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans. The Journal of physiology, 589(Pt 15), 3855-66. (Read full article)
  29. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey J (2011). Implications of group III and IV muscle afferents for high-intensity endurance exercise performance in humans. The Journal of physiology, 589(Pt 21), 5299-309. (Read full article)
  30. Sidhu SK, Weavil JC, Venturelli M, Garten RS, Rossman MJ, Richardson RS, Gmelch BS, Morgan DE, Amann (2014). Spinal mu-opioid receptor-sensitive lower limb muscle afferents determine corticospinal responsiveness and promote central fatigue in upper limb muscle. The Journal of physiology, 592(22), 5011-24. (Read full article)
  31. Blain GM, Mangum TS, Sidhu SK, Weavil JC, Hureau TJ, Jessop JE, Bledsoe AD, Richardson RS, Amann (2016). Group III/IV muscle afferents limit the intramuscular metabolic perturbation during whole body exercise in humans. The Journal of physiology, 594(18), 5303-15. (Read full article)
  32. Broxterman RM, Hureau TJ, Layec G, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson R (2018). Influence of group III/IV muscle afferents on small muscle mass exercise performance: a bioenergetics perspective. The Journal of physiology, 596(12), 2301-2314. (Read full article)
  33. Sidhu SK, Weavil JC, Thurston TS, Rosenberger D, Jessop JE, Wang E, Richardson RS, McNeil CJ, Amann (2018). Fatigue-related group III/IV muscle afferent feedback facilitates intracortical inhibition during locomotor exercise. The Journal of physiology, 596(19), 4789-4801. (Read full article)
  34. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey J (2012). Implications of group III and IV muscle afferents for high intensity endurance exercise performance in humans. The Journal of physiology, 589, 5299-5309.
  35. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey J (2012). Implications of group III and IV muscle afferents for high intensity endurance exercise in humans. The Journal of physiology, 589, 5299-5309.
  36. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Hureau TJ, Bledsoe AD, Buys MJ, Jessop JE, Richardson RS, Amann (2020). The exercise pressor reflex and chemoreflex interaction: cardiovascular implications for the exercising human. The Journal of physiology, 598(12), 2311-2321. (Read full article)
  37. Dempsey JA, Blain GM, Amann (2014). Are type III-IV muscle afferents required for a normal steady-state exercise hyperpnoea in humans?. The Journal of physiology, 592(3), 463-74. (Read full article)
  38. Amann M, Subudhi A, Foster (2004). Influence of testing protocol on ventilatory thresholds and cycling performance. Medicine and science in sports and exercise, 36(4), 613-22. (Read full article)
  39. Amann M, Subudhi AW, Walker J, Eisenman P, Shultz B, Foster (2004). An evaluation of the predictive validity and reliability of ventilatory threshold. Medicine and science in sports and exercise, 36(10), 1716-22. (Read full article)
  40. Francis JT Jr, Quinn TJ, Amann M, LaRoche D (2010). Defining intensity domains from the end power of a 3-min all-out cycling test. Medicine and science in sports and exercise, 42(9), 1769-75. (Read full article)
  41. Elmer SJ, Marshall CS, Wehmanen K, Amann M, McDaniel J, Martin DT, Martin J (2012). Effects of locomotor muscle fatigue on joint-specific power production during cycling. Medicine and science in sports and exercise, 44(8), 1504-11. (Read full article)
  42. Ives SJ, Amann M, Venturelli M, Witman MA, Groot HJ, Wray DW, Morgan DE, Stehlik J, Richardson R (2016). The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure. Medicine and science in sports and exercise, 48(3), 368-76. (Read full article)
  43. Broxterman RM, Layec G, Hureau TJ, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson R (2017). Bioenergetics and ATP Synthesis during Exercise: Role of Group III/IV Muscle Afferents. Medicine and science in sports and exercise, 49(12), 2404-2413. (Read full article)
  44. Ansdell P, Thomas K, Howatson G, Amann M, Goodall (2018). Deception Improves Time Trial Performance in Well-trained Cyclists without Augmented Fatigue. Medicine and science in sports and exercise, 50(4), 809-816. (Read full article)
  45. Layec G, Blain GM, Rossman MJ, Park SY, Hart CR, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Amann M, Richardson R (2018). Acute High-Intensity Exercise Impairs Skeletal Muscle Respiratory Capacity. Medicine and science in sports and exercise, 50(12), 2409-2417. (Read full article)
  46. Rossman MJ, Groot HJ, Amann M, Richardson R (2013). Oxidative stress and COPD: the impact of oral antioxidants on endurance capacity and skeletal muscle fatigue. Medicine and science in sports and exercise, 45, 1235-1243.
  47. Amann (2011). Central and peripheral fatigue: interaction during cycling exercise in humans. Medicine and science in sports and exercise, 43(11), 2039-45. (Read full article)
  48. Rossman MJ, Groot HJ, Reese V, Zhao J, Amann M, Richardson R (2013). Oxidative stress and COPD: the effect of oral antioxidants on skeletal muscle fatigue. Medicine and science in sports and exercise, 45(7), 1235-43. (Read full article)
  49. Trinity JD, McDaniel J, Venturelli M, Fjeldstad AS, Ives SJ, Witman MA, Barrett-O'Keefe Z, Amann M, Wray DW, Richardson R (2011). Impact of body position on central and peripheral hemodynamic contributions to movement-induced hyperemia: implications for rehabilitative medicine. American journal of physiology. Heart and circulatory physiology, 300(5), H1885-91. (Read full article)
  50. Rossman MJ, Trinity JD, Garten RS, Ives SJ, Conklin JD, Barrett-O'Keefe Z, Witman MA, Bledsoe AD, Morgan DE, Runnels S, Reese VR, Zhao J, Amann M, Wray DW, Richardson R (2015). Oral antioxidants improve leg blood flow during exercise in patients with chronic obstructive pulmonary disease. American journal of physiology. Heart and circulatory physiology, 309(5), H977-85. (Read full article)
  51. Sidhu SK, Weavil JC, Venturelli M, Rossman MJ, Gmelch BS, Bledsoe AD, Richardson RS, Amann (2015). Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. American journal of physiology. Heart and circulatory physiology, 309(9), H1479-89. (Read full article)
  52. Andrade DC, Arce-Alvarez A, Toledo C, Díaz HS, Lucero C, Quintanilla RA, Schultz HD, Marcus NJ, Amann M, Del Rio (2018). Revisiting the physiological effects of exercise training on autonomic regulation and chemoreflex control in heart failure: does ejection fraction matter?. American journal of physiology. Heart and circulatory physiology, 314(3), H464-H474. (Read full article)
  53. Trinity JD, Amann M, McDaniel J, Fjeldstad A, Barret-O'Keefe Z, Runnels S, Morgan DN, Wray DW, Richardson R (2010). Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. American journal of physiology. Heart and circulatory physiology, 299, H1693-H1700.
  54. Trinity JD, Amann M, McDaniel J, Fjeldstad AS, Barrett-O'Keefe Z, Runnels S, Morgan DE, Wray DW, Richardson R (2010). Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. American journal of physiology. Heart and circulatory physiology, 299(5), H1693-700. (Read full article)
  55. Weavil JC, Thurston TS, Hureau TJ, Gifford JR, Kithas PA, Broxterman RM, Bledsoe AD, Nativi JN, Richardson RS, Amann (2021). Heart failure with preserved ejection fraction diminishes peripheral hemodynamics and accelerates exercise-induced neuromuscular fatigue. American journal of physiology. Heart and circulatory physiology, 320(1), H338-H351. (Read full article)
  56. Amann M, Pegelow DF, Jacques AJ, Dempsey J (2007). Inspiratory muscle work in acute hypoxia influences locomotor muscle fatigue and exercise performance of healthy humans. American journal of physiology. Regulatory, integrative and comparative physiology, 293(5), R2036-45. (Read full article)
  57. Amann M, Regan MS, Kobitary M, Eldridge MW, Boutellier U, Pegelow DF, Dempsey J (2010). Impact of pulmonary system limitations on locomotor muscle fatigue in patients with COPD. American journal of physiology. Regulatory, integrative and comparative physiology, 299(1), R314-24. (Read full article)
  58. Rossman MJ, Garten RS, Venturelli M, Amann M, Richardson R (2014). The role of active muscle mass in determining the magnitude of peripheral fatigue during dynamic exercise. American journal of physiology. Regulatory, integrative and comparative physiology, 306(12), R934-40. (Read full article)
  59. Weavil JC, Sidhu SK, Mangum TS, Richardson RS, Amann (2015). Intensity-dependent alterations in the excitability of cortical and spinal projections to the knee extensors during isometric and locomotor exercise. American journal of physiology. Regulatory, integrative and comparative physiology, 308(12), R998-1007. (Read full article)
  60. Weavil JC, Hureau TJ, Thurston TS, Sidhu SK, Garten RS, Nelson AD, McNeil CJ, Richardson RS, Amann (2018). Impact of age on the development of fatigue during large and small muscle mass exercise. American journal of physiology. Regulatory, integrative and comparative physiology, 315(4), R741-R750. (Read full article)
  61. Rossman MJ, Garten R, Groot HJ, Reese V, Zhao J, Amann M, Richardson R (2014). Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. American journal of physiology. Regulatory, integrative and comparative physiology, 305, R1163-1170.
  62. Rossman MJ, Garten RS, Groot HJ, Reese V, Zhao J, Amann M, Richardson R (2013). Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. American journal of physiology. Regulatory, integrative and comparative physiology, 305(10), R1163-70. (Read full article)
  63. Laginestra FG, Amann M, Kirmizi E, Giuriato G, Barbi C, Ruzzante F, Pedrinolla A, Martignon C, Tarperi C, Schena F, Venturelli (2021). Electrically induced quadriceps fatigue in the contralateral leg impairs ipsilateral knee extensors performance. American journal of physiology. Regulatory, integrative and comparative physiology, 320(5), R747-R756. (Read full article)
  64. Seifert JG, Kipp RW, Amann M, Gazal (2005). Muscle damage, fluid ingestion, and energy supplementation during recreational alpine skiing. International journal of sport nutrition and exercise metabolism, 15(5), 528-36. (Read full article)
  65. Hoeppli M, Thurston T, Sidhu S, Mangum T, Weavil J, Hureau T, Tang W, Hughen R, Light A, Amann M, Schweinhardt (2016). (352) Differences in psychophysical responses to muscle stimulation in young and old healthy adults. The journal of pain, 17(4S), S63. (Read full article)
  66. Hoeppli ME, Thurston TS, Sidhu SK, Mangum TS, Weavil JC, Hureau TJ, Tang W, Hughen RW, Light AR, Amann M, Schweinhardt (2016). Differences in psychophysical responses to muscle stimulation in young and old healthy adults. The journal of pain, 17(4 Suppl), S63. (Read full article)
  67. Rossman MJ, Venturelli M, McDaniel J, Amann M, Richardson R (2012). Muscle mass and peripheral fatigue: a potential role for afferent feedback?. Acta physiologica (Oxford, England), 206(4), 242-50. (Read full article)
  68. Goodall S, Twomey R, Amann M, Ross EZ, Lovering AT, Romer LM, Subudhi AW, Roach R (2014). AltitudeOmics: exercise-induced supraspinal fatigue is attenuated in healthy humans after acclimatization to high altitude. Acta physiologica (Oxford, England), 210(4), 875-88. (Read full article)
  69. Hureau TJ, Romer LM, Amann (2018). The 'sensory tolerance limit': A hypothetical construct determining exercise performance?. European journal of sport science, 18(1), 13-24. (Read full article)
  70. Weavil JC, Amann (2019). Neuromuscular fatigue during whole body exercise. Current opinion in physiology, 10, 128-136. (Read full article)
  71. Amann M (2012). Limitation to exercise performance at altitude - where is peripheral muscle fatigue important?. 68, 28-30.
  72. Thurston TS, Weavil JC, Hureau TJ, Gifford JR, Georgescu VP, Wan HY, La Salle DT, Richardson RS, Amann (2021). On the implication of dietary nitrate supplementation for the hemodynamic and fatigue response to cycling exercise. Journal of applied physiology (Bethesda, Md., 131(6), 1691-1700. (Read full article)
  73. Lewis MT, Blain GM, Hart CR, Layec G, Rossman MJ, Park SY, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Jessop JE, Bledsoe AD, Amann M, Richardson R (2021). Acute high-intensity exercise and skeletal muscle mitochondrial respiratory function: role of metabolic perturbation. American journal of physiology. Regulatory, integrative and comparative physiology, 321(5), R687-R698. (Read full article)
  74. Venturelli M, Rossman MJ, Ives SJ, Weavil JC, Amann M, Wray DW, Richardson R (2022). Passive leg movement-induced vasodilation and exercise-induced sympathetic vasoconstriction. Autonomic neuroscience, 239, 102969. (Read full article)
  75. Weavil JC, Thurston TS, Hureau TJ, Gifford JR, Aminizadeh S, Wan HY, Jenkinson RH, Amann (2022). Impact of aging on the work of breathing during exercise in healthy men. Journal of applied physiology (Bethesda, Md., 132(3), 689-698. (Read full article)
  76. Weavil JC, Kwon OS, Hughen RW, Zhang J, Light AR, Amann (2022). Gene and protein expression of dorsal root ganglion sensory receptors in normotensive and hypertensive male rats. American journal of physiology. Regulatory, integrative and comparative physiology, 323(2), R221-R226. (Read full article)
  77. Hureau TJ, Broxterman RM, Weavil JC, Lewis MT, Layec G, Amann (2022). On the role of skeletal muscle acidosis and inorganic phosphates as determinants of central and peripheral fatigue: A 31 P-MRS study. The Journal of physiology, 600(13), 3069-3081. (Read full article)
  78. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Morrissey CK, Amann (2022). On the haemodynamic consequence of the chemoreflex and muscle mechanoreflex interaction in women and men: two tales, one story. The Journal of physiology, 600, 3671-3688. (Read full article)
  79. Laginestra FG, Cavicchia A, Vanegas-Lopez JE, Barbi C, Martignon C, Giuriato G, Pedrinolla A, Amann M, Hureau TJ, Venturelli (2022). Prior Involvement of Central Motor Drive does not Impact Performance and Neuromuscular Fatigue in a Subsequent Endurance Task. Medicine and science in sports and exercise, 54, 1751-1760. (Read full article)
  80. Hoeppli ME, Thurston TS, Roy M, Light AR, Amann M, Gracely RH, Schweinhardt (2023). Development of a computerized 2D rating scale for continuous and simultaneous evaluation of two dimensions of a sensory stimulus. Frontiers in psychology, 14, 1127699. (Read full article)
  81. Thurston TS, Weavil JC, Georgescu VP, Wan HY, Birgenheier NM, Morrissey CK, Jessop JE, Amann (2023). The exercise pressor reflex - a pressure-raising mechanism with a limited role in regulating leg perfusion during locomotion in young healthy men. The Journal of physiology, (Read full article)
  82. Thurston TS, Weavil JC, Wan HY, Supiano MA, Kithas PA, Amann (2024). Hypertension Restricts Leg Blood Flow and Aggravates Neuromuscular Fatigue during Human Locomotion in Males. American journal of physiology. Regulatory, integrative and comparative physiology, 327(5), R517-R524. (Read full article)
  83. Iannetta D, Weavil JC, Laginestra FG, Thurston TS, Broxterman RM, Jenkinson RH, Curtis MC, Chang J, Wan HY, Amann (2024). Control of hyperpnoea and pulmonary gas exchange during prolonged exercise: The role of group III/IV muscle afferent feedback. The Journal of physiology, 602(20), 5375-5389. (Read full article)
  84. Wan HY, Bunsawat K, Jarrett CL, Shields KL, Bisconti AV, Weavil JC, Amann (2024). Regional cerebral perfusion and sympathetic activation during exercise in hypoxia and hypercapnia: preliminary insight into 'Cushing's mechanism'. The Journal of physiology, (Read full article)
  85. Ratchford SM, Clifton HL, Gifford JR, LaSalle DT, Thurston TS, Bunsawat K, Alpenglow JK, Wright JB, Amann M, Ryan JJ, Wray D (2025). Impact of Acute Antioxidant and Tetrahydrobiopterin (BH(4)) Administration on Locomotor Muscle Microvascular Function in Patients With Heart Failure. Circulation. Heart failure, 18(6), e012446. (Read full article)
  86. Laginestra FG, Broxterman RM, Iannetta D, Lewis MT, Kofoed JS, Craig JC, Stoddard G, Layec G, Jeong EK, Amann (2025). The influence of biological sex on the metabolic basis of skeletal muscle fatigue in vivo. The Journal of physiology, 603(22), 6881-6894. (Read full article)
  87. Lewis MT, Laginestra FG, Craig JC, Amann M, Richardson RS, Wiseman RW, Broxterman R (2025). Skeletal Muscle Fatigue in Rats Is More Consistently Related to Increased Inorganic Phosphate Concentration Than Acidosis. Acta physiologica (Oxford, England), 241(8), e70083. (Read full article)
  88. Piper M, Hodgson CA, Gadwa J, Hoen M, Knitz MW, Yu J, Corbo S, Olimpo NA, Yee EJ, Zhu Y, Larson KY, Klein C, Amann M, Saviola AJ, Karam S (2025). IL15/IL15Ra complex induces an anti-tumor immune response following radiation therapy only in the absence of Tregs and fails to expand progenitor TCF1+ CD8 T cells. Molecular cancer therapeutics, (Read full article)
  89. Laginestra FG, Weavil JC, Georgescu VP, Thurston TS, Wan HY, Birgenheier NM, Jessop JE, Finn HT, Junkins SR, Amann (2025). On the role of descending drive and group III/IV muscle afferent feedback in modulating corticomotoneuronal excitability during knee-extensor exercise. The Journal of physiology, (Read full article)

Review

  1. Amann (2012). Pulmonary system limitations to endurance exercise performance in humans. Experimental physiology, 97(3), 311-8. (Read full article)
  2. Amann M, Light A (2015). From Petri dish to human: new insights into the mechanisms mediating muscle pain and fatigue, with implications for health and disease. Experimental physiology, 100(9), 989-90. (Read full article)
  3. Amann M, Wan HY, Thurston TS, Georgescu VP, Weavil J (2020). On the Influence of Group III/IV Muscle Afferent Feedback on Endurance Exercise Performance. Exercise and sport sciences reviews, 48(4), 209-216. (Read full article)
  4. Taylor JL, Amann M, Duchateau J, Meeusen R, Rice C (2016). Neural Contributions to Muscle Fatigue: From the Brain to the Muscle and Back Again. Medicine and science in sports and exercise, 48(11), 2294-2306. (Read full article)
  5. Amann (2011). Central and peripheral fatigue: interaction during cycling exercise in humans. Medicine and science in sports and exercise, 43, 2039-2045.
  6. Andrade DC, Arce-Alvarez A, Toledo C, Diaz HS, Lucero C, Quintanilla R, Schultz HD, Marcus NJ, Amann M, and Del Rio (2017). Revisiting the physiological effects of exercise training on autonomicregulation and chemoreflex control in heart failure: does ejection fraction matter?. American journal of physiology. Heart and circulatory physiology, Ahead of print.
  7. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli (2014). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. Autonomic neuroscience, 188, 19-23.
  8. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli (2015). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. Autonomic neuroscience, 188, 19-23. (Read full article)
  9. Wray DW, Amann M, Richardson R (2017). Peripheral vascular function, oxygen delivery and utilization: the impact of oxidative stress in aging and heart failure with reduced ejection fraction. Heart failure reviews, 22(2), 149-166. (Read full article)
  10. Amann M, Kayser (2009). Nervous system function during exercise in hypoxia. High altitude medicine & biology, 10(2), 149-64. (Read full article)
  11. Weavil JC , Amann (2019). Neuromuscular fatigue during whole body exercise. Current opinion in physiology, 10, 1208-136.
  12. Amann (2012). Significance of group III and IV muscle afferents for the endurance exercising human. Australian Physiological Society. Proceedings, 43, 1-7.
  13. Dempsey JA, Amann M, Harms CA, Wetter T (2012). Respiratory system limitations to performance in the healthy athlete: some answers , more questions!. 63(6), 157-162.
  14. Katayama K, Amann (2012). Respiratory muscle fatigue modulates the circulatory response to exercise. 1, 523-530.
  15. Amann M, Sidhu SK, McNeil CJ, Gandevia S (2022). Critical considerations of the contribution of the corticomotoneuronal pathway to central fatigue. The Journal of physiology, (Read full article)
  16. Wan HY, Bunsawat K, Amann (2023). Autonomic Cardiovascular Control during Exercise. American journal of physiology. Heart and circulatory physiology, 325(4), H675-H686. (Read full article)
  17. Iannetta D, Laginestra FG, Wray DW, Amann (2025). Dissecting the exercise pressor reflex in heart failure: A multi-step failure. Autonomic neuroscience, 259, 103269. (Read full article)

Letter

  1. Broxterman RM, Richardson RS, Amann (2015). Less peripheral fatigue after prior exercise is not evidence against the regulation of the critical peripheral fatigue threshold. Journal of applied physiology (Bethesda, Md., 119(12), 1520. (Read full article)
  2. Amann (2012). Somatosensory feedback from locomotor muscles is a significant determinant of central neural drive during exercise - response to a letter to editor. Journal of applied physiology (Bethesda, Md., 105, 105.
  3. Amann M, Dempsey J (2012). Quantifying ventilatory effects of afferent blockade - response to letter to editor. Journal of applied physiology (Bethesda, Md., 110, 861.
  4. Amann M, Richardson RS, Venturelli (2019). Reply to Drouin and Tschakovsky. Journal of applied physiology (Bethesda, Md., 126(3), 797. (Read full article)
  5. Amann (2008). Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. Journal of applied physiology (Bethesda, Md., 104(5), 1543. (Read full article)
  6. Broxterman RM, Layec G, Hureau TJ, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson R (2018). Response. Medicine and science in sports and exercise, 50(8), 1719. (Read full article)
  7. Amann M, Sidhu SK, McNeil CJ, Gandevia S (2023). Transcranial direct current stimulation to enhance athletic performance: Are we there yet? Will we ever get there?. The Journal of physiology, 601(23), 5457-5458. (Read full article)

Abstract

  1. Venturelli M, Amann M, Layec G, Trinity JD, Ives SJ, Yonnet G, Richardson R (2014). Flow mediated vasodilation and limb disuse following a spinal cord injury: An assessment unbiased by vessel diameter. Medicine and science in sports and exercise,
  2. Rossman MJ, Garten RS, Venturelli M, Amann M, Richardson R (2014). The role of active muscle mass in determining the magnitude of peripheral fatigue during dynamic exercise. Medicine and science in sports and exercise,
  3. Weavil JC, Sidhu SK, Mangum TS, Rossman MJ, Garten RS, Richardson RS, Amann (2014). Influence of peripheral fatigue and descending drive on the responsiveness of the corticospinal pathway during cycling exercise. Medicine and science in sports and exercise,
  4. Sidhu SK, Weavil JC, Venturelli M, Richardson RS, Rossman MJ, Garten RS, Amann (2013). Cortical voluntary activation and responsiveness of corticospinal tract to a remote muscle during cycling exercise sustained to task failure. 13, 468.12.
  5. Laginestra FG, Amann M, Kirmizi E, Giuriato G, Ruzzante F, Tarperi C, Venturelli (2019). Electrical stimulation-induced fatigue in the contralateral leg impairs endurance exercise performance.

Newspaper

  1. Kolata G, Amann (2011). One runner's suffering is another's inspiration.

Other

  1. Amann M, Dempsey J (2011). Reply to marcora. Journal of applied physiology (Bethesda, Md., 110(5), 1500. (Read full article)
  2. Amann M, Romer L, Dempsey (2007). To the Editor - Response to Noakes' Letter to the Editor. The Journal of physiology, (Read full article)