A. Wayne Meikle, MD

Languages

  • English

Academic Information

  • Departments: Internal Medicine - Professor Emeritus, Obstetrics/Gynecology - Adjunct Professor
  • Divisions: Endocrinology and Metabolism, General OB/GYN

Board Certification

  • American Board of Internal Medicine (Internal Medicine)
  • American Board of Internal Medicine (Sub: Endocrinology, Diabetes & Metabolism)

Academic Bio

Dr. Meikle’s major research interests are focused on male reproductive endocrinology, prostatic and thyroid neoplasia and laboratory techniques for hormonal assays. The objective of the studies in male twins has been to determine the influence of hereditary and environmental factors in the pathogenesis of lower urinary tract symptoms and benign prostatic hyperplasia. Studies are planned to do linkage analysis of susceptibility genes to the development of benign prostatic hyperplasia. The goal of studies in thyroid neoplasia is to assess the influence of radioactive exposure on the development of autoimmune thyroiditis and thyroid neoplasia. In human prostate cancer cell lines, studies have focused on hormonal and non-hormonal mechanisms that regulate growth and apoptosis of this common neoplasm in aging men. A wide range of endocrine assays has been developed at ARUP.
The experimental techniques used in the laboratory include radioimmunoassay of steroid hormones, growth factors, markers of apoptosis and LC/MS/MS methodology for hormonal assays. Molecular biology techniques include PCR, mRNA analysis and gene sequencing.

Education History

Type School Degree
Chief Resident University of Utah School of Medicine
Internal Medicine
Chief Resident
Fellowship University of Utah Hospital
Endo/Metabolism
Fellow
Residency Vanderbilt University
Internal Medicine
Resident
Internship Vanderbilt University Hospital
Intern
Professional Medical Vanderbilt University
Medicine
M.D.
Research Fellow Vanderbilt University School of Medicine
Biochemistry
Research Fellow
Undergraduate Utah State University
B.S.

Selected Publications

Patent

  1. Kushnir MM, Rockwood AL, Meikle AW (2019). Measurement of Total, Free and Autoantibody Bound Thyroglobulin. Provisional patent application.
  2. Kushnir MM, Rockwood AL, Meikle AW (2011). Methods and Composition for Detecting Steroids. U.S. Patent No. USSN 11/631/,725; Your Ref. No. U-3654; Our Ref. No. 083404-0180. Washington, D.C.:U.S. Patent and Trademark Office.