A. Wayne Meikle, MD
- Departments: Internal Medicine - Professor Emeritus, Obstetrics/Gynecology - Adjunct Professor
- Divisions: Endocrinology and Metabolism, General OB/GYN
- American Board of Internal Medicine (Internal Medicine)
- American Board of Internal Medicine (Sub: Endocrinology, Diabetes & Metabolism)
Dr. Meikle’s major research interests are focused on male reproductive endocrinology, prostatic and thyroid neoplasia and laboratory techniques for hormonal assays. The objective of the studies in male twins has been to determine the influence of hereditary and environmental factors in the pathogenesis of lower urinary tract symptoms and benign prostatic hyperplasia. Studies are planned to do linkage analysis of susceptibility genes to the development of benign prostatic hyperplasia. The goal of studies in thyroid neoplasia is to assess the influence of radioactive exposure on the development of autoimmune thyroiditis and thyroid neoplasia. In human prostate cancer cell lines, studies have focused on hormonal and non-hormonal mechanisms that regulate growth and apoptosis of this common neoplasm in aging men. A wide range of endocrine assays has been developed at ARUP.
The experimental techniques used in the laboratory include radioimmunoassay of steroid hormones, growth factors, markers of apoptosis and LC/MS/MS methodology for hormonal assays. Molecular biology techniques include PCR, mRNA analysis and gene sequencing.
|Chief Resident||University of Utah School of Medicine
|Fellowship||University of Utah Hospital
|Internship||Vanderbilt University Hospital
|Professional Medical||Vanderbilt University
|Research Fellow||Vanderbilt University School of Medicine
|Undergraduate||Utah State University
- Kushnir MM, Rockwood AL, Meikle AW (2019). Measurement of Total, Free and Autoantibody Bound Thyroglobulin. Provisional patent application.
- Kushnir MM, Rockwood AL, Meikle AW (2011). Methods and Composition for Detecting Steroids. U.S. Patent No. USSN 11/631/,725; Your Ref. No. U-3654; Our Ref. No. 083404-0180. Washington, D.C.:U.S. Patent and Trademark Office.