Lara Brewer, PhD

Research Interests

  • Clinical Decision Support Systems
  • Alarm Systems for Patient Monitoring
  • Modeling Gas Exchange
  • Cardiopulmonary Physiology
  • Pharmacodynamic Interactions

Languages

  • English
  • German

Academic Information

  • Departments: Anesthesiology - Research Assistant Professor, Bioengineering - Adjunct Assistant Professor

Academic Office Information

  • 801-587-6393
  • School of Medicine
    Department of Anesthesiology
    30 N 1900 E
    Salt Lake City, UT 84132

Academic Bio

Dr. Lara Brewer is a Research Assistant Professor at the University of Utah. She has research interests in the following areas: clinical decision support and alarm systems for patient monitoring, pharmacodynamic interactions, cardiopulmonary physiology and modeling gas exchange.

Education History

Type School Degree
Doctoral Training University of Utah
Bioengineering
Ph.D.
Graduate Training University of Utah
Bioengineering
M.S.
Undergraduate St. Olaf College
Chemistry and German
B.A.

Selected Publications

Journal Article

  1. Fogarty M, Orr JA, Sakata D, Brewer L, Johnson K, Fang JC, Kuck K (2019). A comparison of ventilation with a non-invasive ventilator versus standard O2 with a nasal cannula for colonoscopy with moderate sedation using propofol. (Epub ahead of print) J Clin Monit Comput.
  2. Ermer S, Brewer L, Orr J, Egan T, Johnson K (2018). Comparison of 7 Different Sensors for Detecting Low Respiratory Rates Using a Single Breath Detection Algorithm in Nonintubated, Sedated Volunteers. Anesth Analg, 129(2), 399-408.
  3. Ermer S, Brewer L, Orr J, Egan TD, Johnson K (2018). Comparison of 7 Different Sensors for Detecting Low Respiratory Rates Using a Single Breath Detection Algorithm in Nonintubated, Sedated Volunteers. Anesth Analg, 129(2), 399-408.
  4. Liu J, Ai C, Zhang B, Wang Y, Brewer LM, Ting CK, Huang D, Yu L (2018). Tracheal sounds accurately detect apnea in patients recovering from anesthesia. J Clin Monit Comput, 33(3), 437-444.
  5. Jing Liu, Chunyu Ai, Bowen Zhang, Yun Wang, Brewer L, Chien-Kun Ting, Desheng Huang, and Lu Yu (2018). Tracheal sounds accurately detect apnea in patients recovering from anesthesia. J Clin Monit Comput, 1-8.
  6. McFarlane DC, Doig AK, Agutter JA, Brewer LM, Syroid ND, Mittu R (2018). Faster clinical response to the onset of adverse events: A wearable metacognitive attention aid for nurse triage of clinical alarms. PLoS ONE, 13(5), e0197157.
  7. McFarlane D, Doig A, Agutter J, Brewer L, Syroid N, and Mittu R (2018). Faster clinical response to the onset of adverse events: A wearable metacognitive attention aid for nurse triage of clinical alarms. PLoS ONE, 13(5), e0197157.
  8. Allen SG, Brewer L, Gillis ES, Pace NL, Sakata DJ, Orr JA (2017). A Turbine-Driven Ventilator Improves Adherence to Advanced Cardiac Life Support Guidelines During a Cardiopulmonary Resuscitation Simulation. Respir Care, 62(9), 1166-1170.
  9. Allen SG, Brewer L, Gillis ES, Pace NL, Sakata DJ, Orr JA (2017). A Turbine-Driven Ventilator Improves Adherence to Advanced Cardiac Life Support Guidelines During a Cardiopulmonary Resuscitation Simulation. Respir Care, 62(9), 1166-1170.
  10. McFarlane, D C, Doig, AK, Agutter, J A, et al (2016). Defeating Information Overload in Health Surveillance using a Metacognitive Aid Innovation from Military Combat Systems. Journal of Defense Modeling and Simulation. Journal of Defense Modeling and Simulation: Applications, Methodology, Technology, 154851291666724.
  11. Naguib M, Brewer L, LaPierre C, Kopman AF, Johnson KB (2016). The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios. Anesth Analg, 123(1), 82-92.
  12. Naguib N, Brewer L, LaPierre C, Kopman A, Johnson KB (2016). The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios. Anesth Analg, 123(1), 82-92.
  13. Patwari N, Brewer L, Tate Q, Kaltiokallio O, Bocca M (2013). Breathfinding: A Wireless Network that Monitors and Locates Breathing in a Home. IEEE J Sel Top Signal Process, PP(99).
  14. Yu L, Ting CK, Hill B, Orr JA, Brewer L, Johnson K, Egan T, Westenskow D (2013). Using the Entropy of Tracheal Sounds to Detect Apnea during Sedation. Anesthesiology, 118(6), 1341-1349.
  15. Brewer L, Orr J, Fulcher E, Markewitz B (2011). Evaluation of a CO2 partial rebreathing functional residual capacity measurement method for use during mechanical ventilation. J Clin Monit Comput, 25(6), 397-404.
  16. Brewer LM, Orr JA, Sherman MR, Fulcher EH, Markewitz BA (2011). Measurement of functional residual capacity by modified multiple breath nitrogen washout for spontaneously breathing and mechanically ventilated patients. Br J Anaesth, 107(5), 796-805.
  17. Brewer LM, Orr JA, Pace NL (2008). Anatomic dead space cannot be predicted by body weight. Respir Care, 53(7), 885-91.
  18. Brewer LM, Haryadi DG, Orr JA (2007). Measurement of functional residual capacity of the lung by partial CO2 rebreathing method during acute lung injury in animals. Respir Care, 52(11), 1480-9.
  19. Brewer L, Orr J, Johnson K, Ermer S, Egan T (Pending). Detecting Ventilatory Depression using Affordable Sensors and Prompting for Patient Self Rescue. Anesth Analg.

Book Chapter

  1. Johnson K, Brewer L, LaPierre C (2014). Consideration for the Induction of Anesthesia. In Ken B Johnson (Ed.), Clinical Pharmacology for Anesthesiology (1, p. 512). New York: McGraw-Hill Education Medical.

Editorial

  1. Tan J, Brewer L (2018). Data-driven Innovation and Technology in Anesthesia: Updates from the Society for Technology in Anesthesia Annual Meeting. Anesthesiology News Special Edition, 2018;suppl, 79-83.

Letter

  1. Orr JA, Kuck K, Brewer LM (2003). Noninvasive cardiac output monitor algorithms are more sophisticated and perform better than indicated in modeling paper. [Letter to the editor]. Anesthesiology, 99(6), 1461-2; author reply 1462.
  2. Kuck K, Orr JA, Brewer LM (2003). Noninvasive cardiac output performance improved after sufficient stabilization time following decrease of ventilation. [Letter to the editor]. Anesthesiology, 99(6), 1460; author reply 1460-1.

Patent

  1. Orr J, Hoehne S, Brewer L (2018). Subject interface appliance and method for delivering a breathable substance to a subject while obtaining gas samples from the airway of the subject. U.S. Patent No. 10,117,599. Washington, D.C.:U.S. Patent and Trademark Office.
  2. MacIntyre A, Brewer L, Wendelken S, Quinn T, Hoehne S (2018). Devices, systems, and methods for measuring blood loss. U.S. Patent No. 10,041,960. Washington, D.C.:U.S. Patent and Trademark Office.
  3. Orr J, Brewer L (2018). System and method of identifying breaths based solely on capnographic information. U.S. Patent No. 9907511. Washington, D.C.:U.S. Patent and Trademark Office.
  4. Orr J, Brewer L (2017). Determining components of total carbon dioxide excreted by a subject. U.S. Patent No. 9,763,601. Washington, D.C.:U.S. Patent and Trademark Office.
  5. Orr J, Brewer L, Westenskow D, Goerges M (2017). Intuitive Presentation of Ventilation Effectiveness. U.S. Patent No. 9,675,300. Washington, D.C.:U.S. Patent and Trademark Office.
  6. Akerman A, Allison SW, Scudiere MB, Cates MR, Beshears DL, Brewer LM, Akerman AJ (2017). Apparatus and system for measuring volume of blood loss. U.S. Patent No. 10,285,596. Washington, D.C.:U.S. Patent and Trademark Office.
  7. Brewer L, Orr J (2017). System and method for determining dead space fraction in an ongoing manner from intermittent blood gas samples. U.S. Patent No. 9,549,690. Washington, D.C.:U.S. Patent and Trademark Office.
  8. Kuck K, Orr J, Brewer L (2013). Methods and apparatus for improving time domain relationships between signals obtained from respiration. U.S. Patent No. 8,398,559. Washington, D.C.:U.S. Patent and Trademark Office.
  9. Westenskow DR, Orr JA, Syroid N, Snell D, Agutter J, Drews F, Lingutla S, Balakrishnan S, Kuck K, Brewer L (2010). System for providing emergency medical care with real-time instructions and associated methods. U.S. Patent No. 7,774,060. Washington, D.C.:U.S. Patent and Trademark Office.
  10. Kuck K, Orr JA, Brewer L (2010). Noninvasive effective lung volume estimation. U.S. Patent No. 7,699,788. Washington, D.C.:U.S. Patent and Trademark Office.
  11. Kuck K, Orr JA, Brewer L (2006). Rebreathing methods including oscillating, substantially equal rebreathing and nonrebreathing periods. U.S. Patent No. 7,135,001. Washington, D.C.:U.S. Patent and Trademark Office.
  12. Kuck K, Orr JA, Brewer L (2006). Algorithms, systems, and methods for estimating carbon dioxide stores, transforming respiratory gas measurements, and obtaining accurate noninvasive pulmonary capillary blood flow and cardiac output measurements. U.S. Patent No. 7,074,196. Washington, D.C.:U.S. Patent and Trademark Office.
  13. Kuck K, Orr JA, Brewer L (2005). Algorithms, systems, and methods for estimating carbon doxide stores, transforming respiratory gas measurements, and obtaining accurate noninvasive pulmonary capillary blood flow and cardiac output measurements. U.S. Patent No. 6,955,651. Washington, D.C.:U.S. Patent and Trademark Office.