Jill Shea

Jill Shea, PhD

Languages spoken: English

Academic Information

Departments Primary - Surgery

Divisions: General Surgery

Academic Office Information

Jill.Shea@hsc.utah.edu

Jill Shea, PhD, is a Research Assistant Professor in the Department of Surgery at the University of Utah School of Medicine and an investigator of the Huntsman Cancer Institute. The central goal of her research is to improve surgical outcomes through translational research.

To accomplish this goal she is currently developing three key areas of research: 1) surgical intervention, 2) imaging, and 3) drug treatment. Specific projects include the development of new nerve guide conduits to improve patient outcomes following traumatic injuries, development of new imaging techniques to treat pancreatic cancer, and development of animal models for pancreas cancer to assist in the development of new therapeutic approaches. Though these projects seem diverse they all share the common theme of advancing current treatments relevant to the Department of Surgery.

Education History

Postdoctoral Fellowship University of Utah
 Postdoctoral Fellow
University of Utah
 Postdoctoral Fellow
Doctoral Training University of Utah
 PhD
University of Oregon
 BS

Selected Publications

Journal Article

  1. Nielson C, Agarwal J, Beck JP, Shea J, Jeyapalina S (2024). Sintered fluorapatite scaffolds as an autograft-like engineered bone graft. J Biomed Mater Res B Appl Biomater, 112(2). (Read full article)
  2. Azapagic A, Agarwal J, Gale B, Li H, Nelson S, Shea J, Sant H (2023). A Novel Vascular Anastomotic Coupling Device for End-to-End Anastomosis of Arteries and Veins. IEEE Trans Biomed Eng, PP(2), 542-552. (Read full article)
  3. Johnson S, Zimmerman B, Odeen H, Shea J, Winkler N, Factor R, Joshi S, Payne A (2023). A Non-Contrast Multi-Parametric MRI Biomarker for Assessment of MR-Guided Focused Ultrasound Thermal Therapies. IEEE Trans Biomed Eng, PP. (Read full article)
  4. Davis B, Wojtalewicz S, Erickson S, Veith J, Simpson A, Sant H, Shea J, Gale B, Agarwal J (2023). Local delivery of FK506 to a nerve allograft is comparable to systemic delivery at suppressing allogeneic graft rejection. PLoS One, 18(3), e0281911. (Read full article)
  5. Wojtalewicz S, Vizmeg J, Erickson S, Lade C, Shea J, Sant H, Magda J, Gale B, Agarwal J, Davis B (2022). Evaluating the influence of particle morphology and density on the viscosity and injectability of a novel long-acting local anesthetic suspension. J Biomater Appl, 37, 8853282221106486. (Read full article)
  6. Jeyapalina S, Hillas E, Beck JP, Agarwal J, Shea J (2021). Fluorapatite and fluorohydroxyapatite apatite surfaces drive adipose-derived stem cells to an osteogenic lineage. J Mech Behav Biomed Mater, 125, 104950. (Read full article)
  7. Tasnim T, Adkins MD, Lim T, Feng H, Magda JJ, Shea JE, Agarwal J, Furse CM, Zhang H (2021). Thermally tunable hydrogel crosslinking mediated by temperature sensitive liposome. Biomed Mater, 16(6). (Read full article)
  8. Zimmerman BE, Johnson SL, Oden HA, Shea JE, Factor RE, Joshi SC, Payne AH (2021). Histology to 3D in vivo MR registration for volumetric evaluation of MRgFUS treatment assessment biomarkers. Sci Rep, 11(1), 18923. (Read full article)
  9. Nelson J, Patel D, Sant HJ, Shea J, Gale BK, Agarwal J (2021). Compression of the vascular wall to create a friction fit in a vascular anastomotic coupler. J Mech Behav Biomed Mater, 123, 104681. (Read full article)
  10. Zimmerman BE, Johnson S, Odeen H, Shea J, Foote MD, Winkler N, Joshi SC, Payne A (2021). Learning Multiparametric Biomarkers for Assessing MR-Guided Focused Ultrasound Treatment of Malignant Tumors. IEEE Trans Biomed Eng, 68(5), 1737-1747. (Read full article)
  11. Camolotto SA, Belova VK, Torre-Healy L, Vahrenkamp JM, Berrett KC, Conway H, Shea J, Stubben C, Moffitt R, Gertz J, Snyder EL (2020). Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4. Gut, 70(5), 900-914. (Read full article)
  12. Labroo P, Ho S, Sant H, Shea JE, Agarwal J, Gale B (2020). Modeling diffusion-based drug release inside a nerve conduit in vitro and in vivo validation study. Drug Deliv Transl Res, 11(1), 154-168. (Read full article)
  13. Davis B, Erickson S, Wojtalewicz S, Simpson A, Metcalf C, Sant H, Shea J, Gale B, Agarwal J (2020). Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model. Int J Pharm, 588, 119703. (Read full article)
  14. Franky Curry, Andrew M Chrysler, Tasmia Tasnim, Jill E Shea, Jayant Agarwal, Cynthia M Furse, and Huanan Zhang (2020). Biostable conductive nanocomposite for implantable subdermal antenna. APL Mater, 8(10).
  15. Curry F, Chrysler AM, Tasnim T, Shea JE, Agarwal J, Furse CM, Zhang H (2020). Biostable conductive nanocomposite for implantable subdermal antenna. APL Mater, 8(10). (Read full article)
  16. Zhang X, Muddana S, Kumar SR, Burton JN, Labroo P, Shea J, Stocking P, Siegl C, Archer B, Agarwal J, Ambati BK (2020). Topical pergolide enhance corneal nerve regrowth following induced corneal abrasion. Invest Ophthalmol Vis Sci, 61(1). (Read full article)
  17. Shea J, Terry C, Edwards K, Agarwal J (2019). Glitazone loaded fat enhances adiponectin production and inhibits breast cancer cell proliferation. Mol Biol Rep, 46(6), 6485-6494. (Read full article)
  18. Davis B, Hilgart D, Erickson S, Labroo P, Burton J, Sant H, Shea J, Gale B, Agarwal J (2019). Local FK506 delivery at the direct nerve repair site improves nerve regeneration. Muscle Nerve, 60(5), 613-620. (Read full article)
  19. Ho S, Labroo P, Lin KM, Sant H, Shea J, Gale B, Agarwal J (2019). Designing a Novel Drug Delivering Nerve Guide: A Preliminary Study. Invest Ophthalmol Vis Sci, 39(3), 294-304. (Read full article)
  20. Kinsey CG, Camolotto SA, Boespflug AM, Guillen KP, Foth M, Truong A, Schuman SS, Shea JE, Seipp MT, Yap JT, Burrell LD, Lum DH, Whisenant JR, Gilcrease GW 3rd, Cavalieri CC, Rehbein KM, Cutler SL, Affolter KE, Welm AL, Welm BE, Scaife CL, Snyder EL, McMahon M (2019). Publisher Correction: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med, 25(5), 861. (Read full article)
  21. Kinsey CG, Camolotto SA, Boespflug AM, Guillen KP, Foth M, Truong A, Schuman SS, Shea JE, Seipp MT, Yap JT, Burrell LD, Lum DH, Whisenant JR, Gilcrease GW 3rd, Cavalieri CC, Rehbein KM, Cutler SL, Affolter KE, Welm AL, Welm BE, Scaife CL, Snyder EL, McMahon M (2019). Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med, 25(4), 620-627. (Read full article)
  22. Labroo P, Hilgart D, Davis B, Lambert C, Sant H, Gale B, Shea JE, Agarwal J (2018). Drug-delivering nerve conduit improves regeneration in a critical-sized gap. Biotechnol Bioeng, 116(1), 143-154. (Read full article)
  23. Brewster R, Gale BK, Sant HJ, Monson K, Shea J, Agarwal J (2018). A Biodegradable Vascular Coupling Device for End-to-End Anastomosis. Invest Ophthalmol Vis Sci, 38(5), 715-723. (Read full article)
  24. Davis B, Wojtalewicz S, Labroo P, Shea J, Sant H, Gale B, Agarwal J (2018). Controlled release of FK506 from micropatterned PLGA films: Potential for application in peripheral nerve repair. Invest Ophthalmol Vis Sci, 13(7), 1247-1252. (Read full article)
  25. Davis B, Wojtalewicz S, Labroo P, Shea J, Sant H, Gale B, Agarwal J (2018). Controlled release of FK506 from micropatterned PLGA films: potential for application in peripheral nerve repair. Neural Regen Res, 13(7), 1247-1252. (Read full article)
  26. Li CW, Davis B, Shea J, Sant H, Gale BK, Agarwal J (2018). Optimization of micropatterned poly(lactic-coglycolic acid) films for enhancing dorsal root ganglion cell orientation and extension. Invest Ophthalmol Vis Sci, 13(1), 105-111. (Read full article)
  27. Li CW, Davis B, Shea J, Sant H, Gale BK, Agarwal J (2018). Optimization of micropatterned poly(lactic-co-glycolic acid) films for enhancing dorsal root ganglion cell orientation and extension. Neural Regen Res, 13(1), 105-111. (Read full article)

Patent

  1. (2018). Methods and devices for connecting nerves. U.S. Patent No. 10842494. Washington, D.C.:U.S. Patent and Trademark Office.