W. Zac Stephens, PhD

Research Interests

  • Air Pollution
  • Immunology
  • Host–Microbe Interaction
  • Microbial Ecology
  • Genomics


Lab Website


  • English

Academic Information

  • Departments: Pathology - Research Assistant Professor
  • Divisions: Microbiology and Immunology

Email: zac.stephens@path.utah.edu

Education History

Type School Degree
Postdoctoral Training University of Utah
Microbiology and Immunology
Postdoctoral Training
Doctoral Training University of Oregon, Institute of Molecular Biology
Molecular Biology & Microbial Ecology
Undergraduate University of Utah

Selected Publications

Journal Article

  1. Petersen C, Bell R, Klag KA, Lee S, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Crotty S4, Boudina S2, OConnell RM, Cox JE, Villanueva JC, Stephens WZ, Round JL (2019). T cell–mediated regulation of the microbiota protects against obesity. Science, 365(6461), eaat9351.
  2. Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, OConnell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL (2019). Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell Host Microbe, 25(2), 285-299.
  3. Chiaro T, Soto R, Kubinak JL, Stephens WZ, Peterson C, Gogokhia L, Bell R, Delgado J, Cox J, Voth W, Brown J, Stillman D, O Connell RM, Tebo A, Round JL (2017). A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice. Sci Transl Med, 8(9), 380.
  4. Zac Stephens W, Burns AR, Stagaman K, Wong S, Rawls JF, Guillemin K, Bohannan BJ (2016). The composition of the zebrafish intestinal microbial community varies across development. ISME J, 10(3), 644-654.
  5. Kubinak JL, Petersen C, Stephens WZ, Soto R, Bake E, OConnell RM, Round JL (2015). MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health. Cell Host Microbe, 17(2), 153-63.
  6. Stephens WZ, Wiles TJ, Martinez ES, Jemielita M, Burns AR, Parthasarathy R, Bohannan BJ, Guillemin K (2015). Identification of Population Bottlenecks and Colonization Factors during Assembly of Bacterial Communities within the Zebrafish Intestine. mBio, 6(6), e01163-15.
  7. Kubinak JL, Stephens WZ, Soto R, Petersen C, Chiaro T, Gogokhia L, Bell R, Ajami NJ, Petrosino JF, Morrison L, Potts WK, Jensen PE, OConnell RM, Round JL (2015). MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection. Nat Commun, 6, 8642.