Sihem Boudina, PhD

Academic Information

  • Departments: Biochemistry - Adjunct Associate Professor, Internal Medicine - Adjunct Associate Professor, Nutrition and Integrative Physiology - Associate Professor, Surgery - Adjunct Assistant Professor
  • Divisions: Cardiothoracic Surgery, Endocrinology and Metabolism

Academic Office Information

  • 801-585-6833
  • George and Dolores Eccles Institute of Human Genetics
    Nutrition and Integrative Physiology
    15 N 2030 E, Room: 3410B
    Salt Lake City, UT 84112

Academic Bio

N/A

Selected Publications

Journal Article

  1. Ghosh R, Vinod V, Symons JD, Boudina S (2020). Protein and Mitochondria Quality Control Mechanisms and Cardiac Aging. Cells, 9(4).
  2. Buffolo M, Pires KM, Ferhat M, Ilkun O, Makaju A, Achenbach A, Bowman F, Atkinson DL, Holland WL, Amri EZ, Chaurasia B, Franklin S, Boudina S (2018). Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Rep, 29(2), 270-282.e5.
  3. Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW II, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, OBrien KD, ORourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L (2020). Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failureā€”A Report from the 2018 National Heart, Lung, and Blood Institute Workshop. Circulation, 140(14), 1205-1216.
  4. Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brs LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K (2019). Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv, 5(9), eaax8352.
  5. Pires KM, Torres NS, Buffolo M, Gunville R, Schaaf C, Davis K, Selzman CH, Gottlieb RA, Boudina S (2019). Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling. Antioxid Redox Signal, 31(6), 444-457.
  6. Petersen C, Bell R, Klag KA, Lee SH, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, OConnell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL (2018). T cell-mediated regulation of the microbiota protects against obesity. Science, 365(6451).
  7. de Paula GSM, Wilieman M, Silva KR, Baptista LS, Boudina S, de Souza LL, Bento-Bernardes T, Asensi KD, Goldenberg RCDS, Pazos-Moura CC (2019). Neuromedin B receptor disruption impairs adipogenesis in mice and 3T3-L1 cells. J Mol Endocrinol, 63(1), 93-102.
  8. Pires KM, Torres NS, Buffolo M, Gunville R, Schaaf C, Davis K, Selzman CH, Gottlieb RA, Boudina S (2019). Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling. (Epub ahead of print) Antioxid Redox Signal.
  9. Runtsch MC, Nelson MC, Lee SH, Voth W, Alexander M, Hu R, Wallace J, Petersen C, Panic V, Villanueva CJ, Evason KJ, Bauer KM, Mosbruger T, Boudina S, Bronner M, Round JL, Drummond MJ, OConnell RM (2019). Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease. PLoS Genet, 15(2), e1007970.
  10. Park SK, La Salle DT, Cerbie J, Cho JM, Bledsoe A, Nelson A, Morgan DE, Richardson RS, Shiu YT, Boudina S, Trinity JD, Symons JD (2018). Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans. Am J Physiol Heart Circ Physiol, 316(1), H106-H112.
  11. Park SK, La Salle DT, Cerbie J, Cho JM, Bledsoe A, Nelson A, Morgan DE, Richardson RS, Shiu YT, Boudina S, Trinity JD, Symons JD (2018). Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans. Am J Physiol Heart Circ Physiol, 316(1), H106-H112.
  12. Cai J, Pires KM, Ferhat M, Chaurasia B, Buffolo MA, Smalling R, Sargsyan A, Atkinson DL, Summers SA, Graham TE, Boudina S (2017). Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk. Cell Rep, 25(7), 1708-1717.e5.