William R. Marchand, MD

Research Interests

  • Bipolar Disorder
  • Neurosciences
  • Basal Ganglia
  • Basal Ganglia Diseases
  • Panic Disorder
  • Traumatic Brain Injury

Languages

  • English

Academic Information

  • Departments: Psychiatry - Professor (Clinical)
  • Divisions: Adult Psychiatry

Board Certification

  • American Board of Psychiatry & Neurology (Psychiatry)

Academic Office Information

  • 801-557-8950
  • Veterans Administration Medical Center
    500 S Foothill Blvd, Room: 2C02
    Salt Lake City, UT 84149

Research Statement

My research focus is on the basal ganglia brain circuitry. I utilize functional and structural MRI to enhance our understanding of these circuits in normal individuals as well the role of these pathways in the neurobiology of neuropsychiatric disorders.

Education History

Type School Degree
Residency University of Utah
Psychiatry Residency
Resident
Professional Medical West Virginia University
Medicine
M.D.
Undergraduate Fairmont State College
Chemistry
B.A.

Selected Publications

Journal Article

  1. Marchand WR, Yabko B, Herrmann T, Curtis H, Lackner R (2019). Treatment Engagement and Outcomes of Mindfulness-Based Cognitive Therapy for Veterans with Psychiatric Disorders. J Altern Complement Med, 25(9), 902-909.
  2. Marchand WR, Klinger W, Block K, VerMerris S, Herrmann TS, Johnson C, Shubin E, Sheppard S (2018). Safety and psychological impact of sailing adventure therapy among Veterans with substance use disorders. Complement Ther Med, 40, 42-47.
  3. Marchand WR, Lee JN, Johnson S, Gale P, Thatcher J (2013). Differences in functional connectivity in major depression versus bipolar II depression. J Affect Disord, 150(2), 527-32.
  4. Suchy Y, Lee JN, Marchand WR (2013). Aberrant cortico-subcortical functional connectivity among women with poor motor control: toward uncovering the substrate of hyperkinetic perseveration. Neuropsychologia, 51(11), 2130-41.
  5. Marchand WR, Lee JN, Suchy Y, Garn C, Chelune G, Johnson S, Wood N (2013). Functional architecture of the cortico-basal ganglia circuitry during motor task execution: correlations of strength of functional connectivity with neuropsychological task performance among female subjects. Hum Brain Mapp, 34(5), 1194-207.
  6. Marchand WR (2013). Mindfulness meditation practices as adjunctive treatments for psychiatric disorders. Psychiatr Clin North Am, 36(1), 141-52.
  7. Marchand WR (2012). Mindfulness-based stress reduction, mindfulness-based cognitive therapy, and Zen meditation for depression, anxiety, pain, and psychological distress. Journal of Psychiatric Practice, 18(4), 233-52.
  8. Marchand WR, Lee JN, Suchy Y, Johnson S, Thatcher J, Gale P (2012). Aberrant functional connectivity of cortico-basal ganglia circuits in major depression. Neurosci Lett, 514(1), 86-90.
  9. Marchand WR, Lee JN, Johnson S, Thatcher J, Gale P, Wood N, Jeong EK (2012). Striatal and cortical midline circuits in major depression: implications for suicide and symptom expression. Prog Neuropsychopharmacol Biol Psychiatry, 36(2), 290-9.
  10. Marchand WR (2012). Self-referential thinking, suicide, and function of the cortical midline structures and striatum in mood disorders: possible implications for treatment studies of mindfulness-based interventions for bipolar depression. Depression Research and Treatment, 2012, 246725.
  11. Marchand WR, Lee JN, Garn C, Thatcher J, Gale P, Kreitschitz S, Johnson S, Wood N (2011). Striatal and cortical midline activation and connectivity associated with suicidal ideation and depression in bipolar II disorder. J Affect Disord, 133(3), 638-45.
  12. Marchand WR, Lee JN, Garn C, Thatcher J, Gale P, Kreitschitz S, Johnson S, Wood N (2011). Aberrant emotional processing in posterior cortical midline structures in bipolar II depression. Prog Neuropsychopharmacol Biol Psychiatry, 35(7), 1729-37.
  13. Marchand WR, Lee JN, Suchy Y, Garn C, Johnson S, Wood N, Chelune G (2011). Age-related changes of the functional architecture of the cortico-basal ganglia circuitry during motor task execution. Neuroimage, 55(1), 194-203.
  14. Marchand WR, Yurgelun-Todd D (2010). Striatal structure and function in mood disorders: a comprehensive review. Bipolar Disord, 12(8), 764-85.
  15. Marchand WR (2010). Cortico-basal ganglia circuitry: a review of key research and implications for functional connectivity studies of mood and anxiety disorders. Brain Struct Funct, 215(2), 73-96.
  16. Lee JN, Hsu EW, Rashkin E, Thatcher JW, Kreitschitz S, Gale P, Healy L, Marchand WR (2010). Reliability of fMRI motor tasks in structures of the corticostriatal circuitry: implications for future studies and circuit function. Neuroimage, 49(2), 1282-8.
  17. Marchand WR, Lee JN, Healy L, Thatcher JW, Rashkin E, Starr J, Hsu E (2009). An fMRI motor activation paradigm demonstrates abnormalities of putamen activation in females with panic disorder. J Affect Disord, 116(1-2), 121-5.
  18. Marchand WR (2009). Attention-Deficit/Hyperactivity Disorder: Review Questions. Hosp Physician, 45, 32-34.
  19. Marchand WR, Thatcher JW (2008). Psychiatric Symptoms of Basal Ganglia Disorders: Evaluation and Management. Hosp Physician, 12(2), 2-16.
  20. Marchand WR, Thatcher JW (2008). Psychopharmacologic Management of Depression in Pregnant Women and Breastfeeding Mothers. Hosp Physician, 44, 8-16.
  21. Marchand WR, Lee JN, Thatcher JW, Hsu EW, Rashkin E, Suchy Y, Chelune G, Starr J, Barbera SS (2008). Putamen coactivation during motor task execution. Neuroreport, 19(9), 957-60.
  22. Marchand WR (2008). Psychiatric Symptoms Associated with Parkinson’s Disease: Review Questions. Hosp Physician, 44(1), 22-24.
  23. Marchand WR (2008). Mood Disorders: Neurobiology, Evaluation and Treatment. Hosp Physician, 12, 2-16.
  24. Marchand WR, Lee JN, Thatcher J, Thatcher GW, Jensen C, Starr J (2007). An fMRI study of frontal-subcortical skeletomotor circuit and dorsolateral prefrontal cortex function using a paced motor activation paradigm. Brain Imaging Behav, 1, 58-67.
  25. Marchand WR, Lee JN, Thatcher JW, Thatcher GW, Jensen C, Starr J (2007). Motor deactivation in the human cortex and basal ganglia. Neuroimage, 38(3), 538-48.
  26. Marchand WR, Lee JN, Thatcher J, Thatcher GW, Jensen C, Starr J (2007). A preliminary longitudinal fMRI study of frontal-subcortical circuits in bipolar disorder using a paced motor activation paradigm. J Affect Disord, 103(1-3), 237-41.
  27. Marchand WR (2007). Panic Disorder: Review Questions. Hosp Physician, 43, 44-46.
  28. Marchand WR, Lee JN, Thatcher GW, Jensen C, Stewart D, Dilda V, Thatcher J, Creem-Regehr SH (2007). A functional MRI study of a paced motor activation task to evaluate frontal-subcortical circuit function in bipolar depression. Psychiatry Res, 155(3), 221-30.
  29. Thatcher JW, Marchand WR, Thatcher GW, Jacobs A, Jensen C (2007). Clinical characteristics and health service use of veterans with comorbid bipolar disorder and PTSD. Psychiatr Serv, 58(5), 703-7.
  30. Thatcher JW, Marchand WR (2007). Tic Disorders in Children: Review Questions. Hosp Physician, 43, 25-27.
  31. Marchand WR, Dilda V (2006). New models of frontal-subcortical skeletomotor circuit pathology in tardive dyskinesia. Neuroscientist, 12(3), 186-98.
  32. Marchand WR, Wirth L, Simon C (2006). Delayed diagnosis of pediatric bipolar disorder in a community mental health setting. Journal of Psychiatric Practice, 12(2), 128-33.
  33. Marchand WR (2006). Evaluation and Treatment of Social Phobia: Review Questions. Hosp Physician, 42, 41-42.
  34. Marchand WR (2006). Suicidality: Review Questions. Hosp Physician, 42, 31-32.
  35. Marchand WR, Bennett PJ, Dilda DS (2005). Evidence for frontal-subcortical circuit abnormalities in bipolar affective disorder. Psychiatry (Edgemont), 2(4), 26-33.
  36. Marchand WR, Clark SC, Wirth L, Simon C (2005). Validity of the parent young mania rating scale in a community mental health setting. Psychiatry (Edgemont), 2(3), 31-5.
  37. Marchand WR (2005). Evaluation and Treatment of Generalized Anxiety Disorder: Review Questions. Hosp Physician, 41, 27-28.
  38. Marchand WR, Wirth L, Simon C (2005). Adverse life events and pediatric bipolar disorder in a community mental health setting. Community Ment Health J, 41(1), 67-75.
  39. Marchand WR, Dilda, V (2005). Neurobiology of Mood Disorders. Hosp Physician, 41, 17-26.
  40. Marchand WR (2005). Evaluation and Treatment of Obsessive-Compulsive Disorder: Review Questions. Hosp Physician, 41, 27-8.
  41. Marchand WR, Wirth L, Simon C (2004). Quetiapine adjunctive and monotherapy for pediatric bipolar disorder: a retrospective chart review. J Child Adolesc Psychopharmacol, 14(3), 405-11.
  42. Marchand WR (2004). Evaluation and Treatment of Mood Disorders in Primary Care: Self-Assessment Questions. Hosp Physician, 40, 31-2.
  43. Marchand WR (2004). Evaluation and Treatment of Psychosis: Review Questions. Hosp Physician, 40, 22-3.
  44. Marchand WR (2003). Recognizing and Treating Bipolar Disorder. Hosp Physician, 39, 21-30.
  45. Francis E, Marchand WR, Hart M, et al (2000). Utilization and Outcome in an Overnight Psychiatric Observation Program at a Veterans Affairs Medical Center. Psychiatr Serv, 51, 92-5.
  46. Marchand WR (1988). The effect of an educational program on the desire for treatment among impaired medical students. J Nerv Ment Dis, 176(6), 372-3.
  47. Marchand WR, Palmer CA, Gutmann L, et al (1986). Medical Students' Perceptions of having Symptoms of Impairment and of the Need to Seek Counseling. J Med Educ, 61, 744.
  48. Marchand WR, Palmer CA, Gutmann L, Brogan WC 3rd (1985). Medical student impairment: a review of the literature. W V Med J, 81(11), 244-8.

Book

  1. Marchand, WR (2012). Depression and Bipolar Disorder: Your Guide to Recovery. Boulder: Bull Publishing Company.

Book Chapter

  1. Marchand, WR (2012). The neurocircuitry of fear and pleasure: Implications for the neurobiology of anxiety and affective disorders. In Columbus, F (Eds.), Advances in Psychology Research Volume 81. Hauppauge, NY: Nova Science Publishers, Inc.
  2. Marchand WR, Yurgelun-Todd DA (2011). Functional Imaging of bipolar illness. In Shenton ME; Turetsky BI; (Ed.), Understanding Neuropsychiatric Disorders: Insights From Neuroimaging (pp. 109-124). New York: Cambridge University Press.

Abstract

  1. Shi Y, Joshi S, Lee JN, Marchand WR, Rashkin E, Hsu Ew (2008). Reproducibility of Fractional Anisotropy and Mean Diffusivity in Diffusion Tensor Imaging at 3.0 T [Abstract]. Proc Intl Soc Mag Reson Med, 16, 341.
  2. Marchand WR, Lee JN, Thatcher JW, Hsu EW, Rashkin E, Suchy Y, Chelune G, Starr J, Barbera SS (2008). Putamen Activation and Connectivity during Task Execution Suggests a Mechanism for the Etiology of Motor Symptoms in Psychiatric Disorders [Abstract]. Biological Psychiatry, 63 (supplement 1), 75S.
  3. Marchand WR, Thatcher GW, Lee J, Creem-Regehr S, Bennett P, Dilda V, Stewart D, Jensen C, Hedges D (2005). Functional Magnetic Resonance Imaging of Frontal-subcortical Circuits in Bipolar Depression [Abstract]. Bipolar Disorders, 7 (supplement 2), 75.

Newspaper

  1. Marchand WR (1992). Patients say doctors don't communicate. Ogden Standard-Examiner.
  2. Marchand WR (1992). Communication. Ogden Standard-Examiner.
  3. Marchand WR (1992). Relax. You can beat stress, depression. Hilltop Times.
  4. Marchand WR (1991). Got the day-after Christmas blues? These tips will help you feel better. Ogden Standard-Examiner.
  5. Marchand WR (1991). Anxiety. Ogden Standard-Examiner.
  6. Marchand WR (1991). Oh So Shy: Severe cases of shyness - called social phobia - can become debilitating. Ogden Standard-Examiner.
  7. Marchand WR (1991). Depression. Ogden Standard-Examiner.
  8. Marchand WR (1991). Silver Linings: Forecast Optimistic For Kids. Hilltop Times.
  9. Marchand WR (1991). Easing wartime stress at home. Hilltop Times.
  10. Marchand, WR (1991). "Ask the Psychiatrist," Question and Answer Column. Ogden Standard Examiner.
  11. Marchand WR (1990). You can put the merry back into Christmas by getting rid of the stress. Ogden Standard-Examiner.
  12. Marchand WR (1990). Feeling Stressed? Reach out to others - you're not a burden. Air Force Times.
  13. Marchand WR (1990). Can Conflict with Supervisors Be Prevented? The Pychiatric Times.
  14. Marchand WR (1990). MD struggles to believe in psychotherapy. American Medical News.
  15. Marchand WR (1990). Problems resolved with some honest communications. The Salt Lake Tribune.
  16. Marchand WR (1989). Physicians Must Be Aware of Attitudes Toward Addiction. The Pychiatric Times.

Other

  1. Marchand WR (1992). Keeping the Lines Open. How to speak to your doctor - and get her to speak back! Weight Watchers Magazine.
  2. Marchand WR (1991). How Mood Affects Weight. Weight Watchers Magazine.

Video/Film/CD/Web/Podcast

  1. Marchand, WR (2011). Psychiatry Board Review Application Volume 3 [Web]. Physician Board Review. Available: http://www.physicianboardreview.com/.
  2. Marchand, WR (2011). Psychiatry Board Review Application Volume 2 [Web]. Physician Board Review. Available: http://www.physicianboardreview.com/.
  3. Marchand, WR (5/2010). Psychiatry Board Review Application Volume 1 [Web]. Physician Board Review. Available: http://www.physicianboardreview.com/.

Video