Samuel M. Brown, MD, MS


  • English
  • Russian
  • Spanish

Academic Information

  • Departments: Internal Medicine - Associate Professor
  • Divisions: Pulmonary

Board Certification

  • American Board of Internal Medicine (Sub: Pulmonary Disease)
  • American Board of Internal Medicine (Sub: Critical Care Medicine)

Academic Office Information

  • 801-507-6556
  • Intermountain Medical Center
    Shock Trauma ICU
    5121 Cottonwood Street
    Murray, UT 84107

Academic Bio

Samuel Brown graduated summa cum laude from Harvard College in Linguistics with a minor in Russian, then received his MD from Harvard Medical School, where he was a National Scholar and Massachusetts Medical Society Scholar. He completed residency at Massachusetts General Hospital, where he remained on faculty as an Instructor in General Medicine at Harvard Medical School before moving to the University of Utah, where he completed fellowship training. He is Associate Professor of Pulmonary and Critical Care Medicine and Medical Ethics and Humanities at the University of Utah, based clinically at the Shock Trauma ICU at Intermountain Medical Center in Salt Lake City.

Dr. Brown uses advanced statistical methods to study two main sets of problems: heart dysfunction during life-threatening infection and the human side of intensive care. His physiological research incorporates ultrasound images of the heart and complex analysis of heart rate and blood pressure to understand better how to prevent death from sepsis. Dr. Brown also merges quantitative and qualitative/humanistic approaches to making medicine human through the Center for Humanizing Critical Care, which he founded and directs at Intermountain Medical Center. The Center works to improve the outcomes that matter most to patients and families and to develop systems of care that best protect the human dignity of patients and families as they face life-threatening illness. On occasional free weekends, he studies cultural history, with a particular emphasis on questions of embodiment, sickness, and death. He has published widely in medicine, ethics, and history.

Education History

Type School Degree
Fellowship University of Utah School of Medicine/SLC VA Hospital, Department of Anesthesia
Transthoracic Echocardiography
Graduate Training University of Utah
Clinical Investigation
Fellowship University of Utah
Pulmonary and Critical Care Medicine
Residency Massachusetts General Hospital
Internal Medicine
Internship Massachusetts General Hospital
Internal Medicine
Professional Medical Harvard Medical School
Undergraduate Harvard College
Linguistics and Russian

Selected Publications

Journal Article

  1. Brown SM, Grissom CK, Moss M, Rice TW, Schoenfeld D, Hou PC, Thompson BT, Brower RG (2016). Nonlinear Imputation of Pao2/Fio2 From Spo2/Fio2 Among Patients With Acute Respiratory Distress Syndrome. Chest, 150(2), 307-13.
  2. Walkey AJ, Pencina KM, Knox D, Kuttler KG, DAgostino RB Sr, Benjamin EJ, Brown SM (2015). Five-Year Risk of Mechanical Ventilation in Community-Dwelling Adults: The Framingham-Intermountain Anticipating Life Support Study. J Am Geriatr Soc, 63(10), 2082-8.
  3. Lanspa MJ, Pittman JE, Hirshberg EL, Wilson EL, Olsen T, Brown SM, Grissom CK (2015). Association of left ventricular longitudinal strain with central venous oxygen saturation and serum lactate in patients with early severe sepsis and septic shock. Crit Care, 19(1), 304.
  4. Knox DB, Lanspa MJ, Kuttler KG, Brewer SC, Brown SM (2015). Phenotypic clusters within sepsis-associated multiple organ dysfunction syndrome. Intensive Care Med, 41(5), 814-22.
  5. Pratt CM, Hirshberg EL, Jones JP, Kuttler KG, Lanspa MJ, Wilson EL, Hopkins RO, Brown SM (2015). Long-term outcomes after severe shock. Shock, 43(2), 128-32.
  6. Grissom CK, Hirshberg EL, Dickerson JB, Brown SM, Lanspa MJ, Liu KD, Schoenfeld D, Tidswell M, Hite RD, Rock P, Miller RR 3rd, Morris AH (2015). Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*. Crit Care Med, 43(2), 288-95.
  7. Brown SM, Grissom CK, Rondina MT, Hoidal JR, Scholand MB, Wolff RK, Morris AH, Paine R 3rd (2015). Polymorphisms in key pulmonary inflammatory pathways and the development of acute respiratory distress syndrome. Exp Lung Res, 41(3), 155-62.
  8. Rondina MT, Carlisle M, Fraughton T, Brown SM, Miller RR 3rd, Harris ES, Weyrich AS, Zimmerman GA, Supiano MA, Grissom CK (2015). Platelet-monocyte aggregate formation and mortality risk in older patients with severe sepsis and septic shock. J Gerontol A Biol Sci Med Sci, 70(2), 225-31.
  9. Brown SM, Tate MQ, Jones JP, Kuttler KG, Lanspa MJ, Rondina MT, Grissom CK, Mathews VJ (2015). Coefficient of Variation of Coarsely Sampled Heart Rate is Associated With Early Vasopressor Independence in Severe Sepsis and Septic Shock. J Intensive Care Med, 30(7), 420-5.
  10. Brown SM, Tate Q, Jones JP, Knox DB, Kuttler KG, Lanspa M, Rondina MT, Grissom CK, Behera S, Mathews VJ, Morris A (2013). Initial fractal exponent of heart rate variability is associated with success of early resuscitation in patients with severe sepsis or septic shock: a prospective cohort study. J Crit Care, 28(6), 959-63.
  11. Brown SM, Lanspa MJ, Jones JP, Kuttler KG, Li Y, Carlson R, Miller RR 3rd, Hirshberg EL, Grissom CK, Morris AH (2013). Survival after shock requiring high-dose vasopressor therapy. Chest, 143(3), 664-671.
  12. Miller RR 3rd, Dong L, Nelson NC, Brown SM, Kuttler KG, Probst DR, Allen TL, Clemmer TP (2013). Multicenter implementation of a severe sepsis and septic shock treatment bundle. Am J Respir Crit Care Med, 188(1), 77-82.
  13. Brown SM, Pittman J, Miller Iii RR, Horton KD, Markewitz B, Hirshberg E, Jones J, Grissom CK (2011). Right and left heart failure in severe H1N1 influenza A infection. Eur Respir J, 37(1), 112-8.

Edited Book

  1. Brown SM, Blaivas M, Hirshberg E, Kasal J, Pustavoitau A (Eds.) (2015). Comprehensive Critical Care Ultrasound. Chicago, IL: Society of Critical Care Medicine.