DeAngelis, Margaret Mary, PhD

Languages

  • English

Academic Information

  • Departments: Ophthalmology/Visual Sciences - Professor, Pharmacotherapy - Adjunct Professor, Population Health Sciences - Adjunct Professor

Academic Office Information

  • 801-581-2352
  • John A. Moran Eye Center
    Ophthalmology and Visual Sciences
    65 N Mario Capecchi
    Salt Lake City, UT 84132

Academic Bio

Dr. DeAngelis is currently a Professor at the University of Utah School of Medicine and has focused her career on vision research since 1999, when she received a post-doctoral fellowship training grant on macular degeneration as part of the Molecular Basis of Eye Disease program at Harvard Medical School. Working in collaboration with clinicians throughout her career, she has recruited, ascertained, and developed large patient populations of both families and unrelated case-controls to study the genetic and epidemiologic underpinnings of both common and rare ophthalmic conditions.

Specifically, the DeAngelis’ group utilizes a systems-biology based approach to pinpoint disease causality. To this end, utilizing both families and then replication in unrelated case-controls to study DNA, gene expression and protein, coupled with epidemiological information, her group has identified novel genes and pathways associated with common diseases including age-related macular degeneration (AMD) (RORA, ROBO1, CYP24A1) and then replicated these findings in diverse patient populations. RORA, an intracellular target of cholesterol, was shown to interact with other established AMD genetic risk factors (ARMS2/HTRA1) thus furthering the development of a unifying hypothesis underlying AMD pathophysiology.

The laboratory also continues to recruit and characterize ethnically diverse populations throughout the world in an effort to understand the origin and significance of genetic variation, environmental factors, and diseases that co-occur with other blinding eye diseases. The creation of a well-characterized fresh donor eye repository by Dr. DeAngelis to study diseases, including AMD and glaucoma, has enabled her laboratory to employ and develop multi-omic approaches, including RNASeq, allele specific expression, epigenetic, and bioinformatic tools to delineate disease mechanism. This is done in an effort to develop appropriate preventive and therapeutic targets for these devastating forms of blindness.

Recent work from the DeAngelis lab identifying Vitamin D pathway genetic risk variants in AMD has resulted in clinical trials for age-related macular degeneration.

Dr. DeAngelis serves on the senior executive committee/steering committee for the International AMD Genomics Consortium sponsored by NEI/NIH. Dr. DeAngelis is also committed to teaching and mentoring the next generation of scientists and clinician-scientists, and she is a mentor and advisor to undergraduate, graduate, medical students, fellows, and junior faculty.

Dr. DeAngelis has over 60 peer-reviewed publications, book chapters and reviews. She serves on several editorial boards and national and international grant review panels. Her work has been generously funded by the NEI; The ALSAM Foundation; The Skaggs Research Foundation; The Bank of America/Thome Memorial Fund; Carl Reeves Foundation; Macular Degeneration Foundation; and Center of Aging, Division of Geriatrics, University of Utah.

Research Statement

Dr. DeAngelis is currently a Professor at the University of Utah School of Medicine and has focused her career on vision research since 1999, when she received a post-doctoral fellowship training grant on macular degeneration as part of the Molecular Basis of Eye Disease program at Harvard Medical School. Working in collaboration with clinicians throughout her career, she has recruited, ascertained, and developed large patient populations of both families and unrelated case-controls to study the genetic and epidemiologic underpinnings of both common and rare ophthalmic conditions.

Education History

Type School Degree
Postdoctoral Fellowship Harvard Medical School - Thaddeus P. Dryja, M.D.
Genetics, Epidemiology and Ophthalmology
Postdoctoral Fellow
Doctoral Training Louisiana State University Medical Center, School of Graduate Studies
Molecular Biology, Human/Mouse Genetics and Neuroscience
Ph.D.
Graduate Training Medical College of Virginia
Physiology
M.S.
Undergraduate Clark University
Environment, Technology and Society
B.A.

Selected Publications

Journal Article

  1. Morgan DJ, DeAngelis MM (). Differential Gene Expression in Age-Related Macular Degeneration. a017210. doi: 10.1101/cshperspect.a017210. Review.PMID: 25342062. Cold Spring Harb Perspect Med, 5(8).
  2. Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H (2012). Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS ONE, 7(4), e35295.
  3. Daniels AB, Lee JE, Macconaill LE, Palescandolo E, Van Hummelen P, Adams SM, Deangelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK (2012 Nov). High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Invest Ophthalmol Vis Sci, 53(11), 6991-6.
  4. Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM (2011). Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. PLoS ONE, 6(10), e25775.
  5. Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM (2011 Oct). Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. Hum Genomics, 5(6), 538-68.
  6. Hageman GS, Gehrs K, Lejnine S, Bansal AT, Deangelis MM, Guymer RH, Baird PN, Allikmets R, Deciu C, Oeth P, Perlee LT (2011 Jul 1). Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration. Hum Genomics, 5(5), 420-40.
  7. Feehan M, Hartman J, Durante R, Morrison MA, Miller JW, Kim IK, Deangelis MM (2011). Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics. BMC Med Genet, 12, 83.
  8. Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, Deangelis MM, Haider NB (2011). Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS ONE, 6(7), e21858.
  9. Deangelis MM, Silveira AC, Carr EA, Kim IK (2011 May). Genetics of age-related macular degeneration: current concepts, future directions. Semin Ophthalmol, 26(3), 77-93.
  10. Schaumberg DA, Chasman D, Morrison MA, Adams SM, Guo Q, Hunter DJ, Hankinson SE, DeAngelis MM (2010 Nov). Prospective study of common variants in the retinoic acid receptor-related orphan receptor alpha gene and risk of neovascular age-related macular degeneration. Arch Ophthalmol, 128(11), 1462-71.
  11. Chan RP, Yonekawa Y, Morrison MA, Sun G, Wong RK, Perlman JM, Chiang MF, Lee TC, Hartnett ME, Deangelis MM (2010). Association between assisted reproductive technology and advanced retinopathy of prematurity. Clin Ophthalmol, 4, 1385-90.
  12. Chen W, Stambolian D, Edwards AO, Branham KE, Othman M, Jakobsdottir J, Tosakulwong N, Pericak-Vance MA, Campochiaro PA, Klein ML, Tan PL, Conley YP, Kanda A, Kopplin L, Li Y, Augustaitis KJ, Karoukis AJ, Scott WK, Agarwal A, Kovach JL, Schwartz SG, Postel EA, Brooks M, Baratz KH, Brown WL, Brucker AJ, Orlin A, Brown G, Ho A, Regillo C, Donoso L, Tian L, Kaderli B, Hadley D, Hagstrom SA, Peachey NS, Klein R, Klein BE, Gotoh N, Yamashiro K, Ferris Iii F, Fagerness JA, Reynolds R, Farrer LA, Kim IK, Miller JW, Corton M, Carracedo A, Sanchez-Salorio M, Pugh EW, Doheny KF, Brion M, Deangelis MM, Weeks DE, Zack DJ, Chew EY, Heckenlively JR, Yoshimura N, Iyengar SK, Francis PJ, Katsanis N, Seddon JM, Haines JL, Gorin MB, Abecasis GR, Swaroop A (2010 Apr 20). Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A, 107(16), 7401-6.
  13. Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM (2010 Mar 31). Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res, 50(7), 698-715.
  14. Yan T, Yang YN, Cheng X, DeAngelis MM, Hoh J, Zhang H (2009 Jan). Genotypic association analysis using discordant-relative-pairs. Ann Hum Genet, 73(1), 84-94.
  15. Andreoli MT, Morrison MA, Kim BJ, Chen L, Adams SM, Miller JW, DeAngelis MM, Kim IK (2009 Dec). Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration. Am J Ophthalmol, 148(6), 869-74.
  16. Deangelis MM, Ji F, Adams S, Morrison MA, Harring AJ, Sweeney MO, Capone A Jr, Miller JW, Dryja TP, Ott J, Kim IK (2008 Jul). Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration. Ophthalmology, 115(7), 1209-1215.e7.
  17. Fan BJ, Pasquale L, Grosskreutz CL, Rhee D, Chen T, DeAngelis MM, Kim I, del Bono E, Miller JW, Li T, Haines JL, Wiggs JL (2008). DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity. BMC Med Genet, 9, 5.
  18. Yu HG, Liu X, Kiss S, Connolly E, Gragoudas ES, Michaud NA, Bulgakov OV, Adamian M, DeAngelis MM, Miller JW, Li T, Kim IK (2008 Jun). Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1. Invest Ophthalmol Vis Sci, 49(6), 2599-605.
  19. Zhang H, Morrison MA, Dewan A, Adams S, Andreoli M, Huynh N, Regan M, Brown A, Miller JW, Kim IK, Hoh J, Deangelis MM (2008). The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med Genet, 9, 51.
  20. Kim IK, Ji F, Morrison MA, Adams S, Zhang Q, Lane AM, Capone A, Dryja TP, Ott J, Miller JW, DeAngelis MM (2008). Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration. Mol Vis, 14, 1487-95.
  21. DeAngelis MM, Ji F, Kim IK, Adams S, Capone A Jr, Ott J, Miller JW, Dryja TP (2007 Jan). Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration. Arch Ophthalmol, 125(1), 49-54.
  22. DeAngelis MM, Lane AM, Shah CP, Ott J, Dryja TP, Miller JW (2004 Apr). Extremely discordant sib-pair study design to determine risk factors for neovascular age-related macular degeneration. Arch Ophthalmol, 122(4), 575-80.
  23. DeAngelis MM, Grimsby JL, Sandberg MA, Berson EL, Dryja TP (2002 Mar). Novel mutations in the NRL gene and associated clinical findings in patients with dominant retinitis pigmentosa. Arch Ophthalmol, 120(3), 369-75.
  24. Rivolta C, Sharon D, DeAngelis MM, Dryja TP (2002 May 15). Retinitis pigmentosa and allied diseases: numerous diseases, genes, and inheritance patterns. Hum Mol Genet, 11(10), 1219-27.
  25. DeAngelis MM, McGee TL, Keats BJ, Slim R, Berson EL, Dryja TP (2001 Mar). Two families from New England with usher syndrome type IC with distinct haplotypes. Am J Ophthalmol, 131(3), 355-8.
  26. Pelias MZ, DeAngelis MM (1999 Summer). The new genetic technologies: new options, new hope, and new challenges. Loyola Law Review, 45(2), 287-306.
  27. DeAngelis MM, Doucet JP, Drury S, Sherry ST, Robichaux MB, Den Z, Pelias MZ, Ditta GM, Keats BJB, Deininger PL, Batzer MA (). Assembly of a high-resolution map of the Acadian Usher syndrome region and localization of the nuclear EF-hand acidic gene. Biochimica et Biophysica Acta. Biochim Biophys Acta, 1407(1), 84-91.
  28. DeAngelis MM, Doucet JP, Drury S, Sherry ST, Robichaux MB, Den Z, Pelias MZ, Ditta GM, Keats BJ, Deininger PL, Batzer MA (1998 Jul 1). Assembly of a high-resolution map of the Acadian Usher syndrome region and localization of the nuclear EF-hand acidic gene. Biochim Biophys Acta, 1407(1), 84-91.
  29. Vinas AM, Drury SS, DeAngelis MM, Den Z, Huang JM, Berlin CI, Hunt JD, Batzer MA, Deininger PL, Keats BJ (1998 Sep 30). The mouse deafness locus (dn) is associated with an inversion on chromosome 19. Biochim Biophys Acta, 1407(3), 257-62.
  30. Scott DA, Greinwald JH Jr, Marietta JR, Drury S, Swiderski RE, Vinas A, DeAngelis MM, Carmi R, Ramesh A, Kraft ML, Elbedour K, Skworak AB, Friedman RA, Srikumari Srisailapathy CR, Verhoeven K, Van Gamp G, Lovett M, Deininger PL, Batzer MA, Morton CC, Keats BJ, Smith RJ, Sheffield VC (1998 Jul 30). Identification and mutation analysis of a cochlear-expressed, zinc finger protein gene at the DFNB7/11 and dn hearing-loss loci on human chromosome 9q and mouse chromosome 19. Gene, 215(2), 461-9.
  31. Bouyge-Moreau I, Rondeau G, Avet-Loiseau H, Andr MT, Bzieau S, Chrel M, Salen S, Cadoret E, Shaikh T, DeAngelis MM, Arcot S, Batzer M, Moisan JP, Devilder MC (). Construction of a 780-kb PAC, BAC and cosmid contig encompassing the minimal critical deletion involved in B cell Chronic Lymphocytic Leukemia at 13q14.3. Genomics, 46, 183-190.
  32. Arcot SS, DeAngelis MM, Sherry ST, Adamson AW, Lamerdin JE, Deininger PL, Carrano AV, Batzer MA (1997 Sep). Identification and characterization of two polymorphic Ya5 Alu repeats. Mutat Res, 382(1-2), 5-11.
  33. Dietrich WF, Miller J, Steen R, Merchant MA, Damron-Boles D, Husain Z, Dredge R, Daly MJ, Ingalls KA, OConnor TJ, Evans CA, DeAngelis MM, Levinson DM, Kruglyak L, Goodman N, Copeland NG, Jenkins NA, Hawkins TL, Stein L, Page DC, Lander ES (). A comprehensive genetic map of the mouse genome. Nature, 380, 149-152.
  34. DeAngelis MM, Wang DG, Hawkins TL (1995 Nov 25). Solid-phase reversible immobilization for the isolation of PCR products. Nucleic Acids Res, 23(22), 4742-3.
  35. Hudson TJ, Stein LD, Gerety SS, Ma J, Castle AB, Silva J, Slonim DK, Baptista R, Kruglyak L, Xu SH, Hu X, Colbert AM, Rosenberg C, Reeve-Daly MP, Rozen S, Hui L, Wu X, Vestergaard C, Wilson KM, Bae JS, Maitra S, Ganiatsas S, Evans CA, DeAngelis MM, Ingalls KA, Nahf RW, Horton LT Jr, Anderson MO, Collymore AJ, Ye W, Kouyoumjian V, Zemsteva IS, Tam J, Devine R, Courtney DF, Renaud MT, Nguyen H, OConnor TJ, Fizames C, Faure S, Gyapay G, Dib C, Morissette J, Orlin JB, Birren BW, Goodman N, Weissenbach J, Hawkins TL, Foote S, Page DC, Lander ES (1995 Dec 22). An STS-based map of the human genome. Science, 270(5244), 1945-54.
  36. DeAngelis MM, Hayes RL, Lyeth BG (1994 Aug 8). Traumatic brain injury causes a decrease in M2 muscarinic cholinergic receptor binding in the rat brain. Brain Res, 653(1-2), 39-44.
  37. Potashner SJ, Dymczyk L, Deangelis MM (1988 Jan). D-aspartate uptake and release in the guinea pig spinal cord after partial ablation of the cerebral cortex. J Neurochem, 50(1), 103-11.

Book Chapter

  1. Hartnett ME, DeAngelis MM (). The Role of Reactive Oxygen Species and Oxidative Signaling in Retinopathy of Prematurity. In Studies on Retinal and Choroidal Disorders. Humana (Springer).
  2. DeAngelis MM, Ji F (). Genetics of Age-related Macular Degeneration. In Albert DM, Miller JW (Eds.), Albert & Jakobiec's Principles & Practice of Ophthalmology (3rd, 2, pp. 1881-1900). Philadelphia, PA: Saunders.
  3. Yonekawa Y, Sun G, Chan RVP Lee TC, Morrison MA, Adams SM, DeAngelis MM (). Retinopathy of Prematurity: Disease Mechanisms and Treatment Modalities. In Mercier EB (Ed.), Non-Age Related Macular Degeneration. Hauppauge, NY: Nova Science Publishers.
  4. Andreoli MT, DeAngelis MM (). Genetic and Epidemiological Contributions Underlying Diabetic Retinopathy. In Mercier EB (Ed.), Non-Age Related Macular Degeneration. Hauppauge, NY: Nova Science Publishers.
  5. DeAngelis MM, Batzer MA (). Genome Sequence Analysis. In Macmillan Reference Limited (Ed.), Encyclopedia of Life Sciences. London, UK: Stockton Press.
  6. DeAngelis MM, Donaldson CJ, Ditta GM, Buckley LM, Doucet JP, Den Z, Drury S, Pelias MZ, Deininger PL, Keats BJB, Batzer MA (). Physical maps as molecular tools to identify disease genes. In Berlin CI, Keats BJB (Eds.), Genetics and Hearing Loss. San Diego, CA: Singular Publishing Group.
  7. Drury S, Scott D, Den Z, DeAngelis, MM, Batzer MA, Sheffield VC, Smith RJH, Deininger PL, Keats BJB (). Mouse models and progress in human deafness research. In Berlin CI, Keats BJB (Eds.), Genetics and Hearing Loss. San Diego, CA: Singular Publishing Group.

Case Report

  1. Tantravahi SK, Williams LB, Digre KB, Creel DJ, Smock KJ, DeAngelis MM, Clayton FC, Vitale AT, Rodgers GM (2012 Mar). An inherited disorder with splenomegaly, cytopenias, and vision loss. Am J Med Genet A, 158A(3), 475-81.
  2. Jakobiec FA, Zakka FR, DAmato R, Deangelis MM, Walton DS, Rao RC (2011 Dec). Unilateral sporadic retinal dysplasia: results of histopathologic, immunohistochemical, chromosomal, genetic, and VEGF-A analyses. J AAPOS, 15(6), 579-86.

Editorial

  1. DeAngelis MM (2006 Sep). Retinitis pigmentosa and common variable immunodeficiency disease: associated or separate? Utah Special Educator, 99(9), 914.

Abstract

  1. Haider N, Yang A, Yuan Y, DeAngelis M (). The Role of Robo1 in Retinal Vascular Disorders. Washington, D.C [Abstract]. The American Society of Human Genetics.
  2. DeAngelis M, Morrison MA, Silveira AC, Adams SM, Kotoula MG, Tsironi EE, Zacharaki F, Kim IK, Miller JW, Haider NB, Jelcick A, Hollis BW, Chen R, Hageman GS, Schumberg DA (). Genetic Data Suggest a Novel Association Between the Vitamin D Pathway and Development of Age-related Macular Degeneratoin. Washington, D.C [Abstract]. The American Society of Human Genetics.
  3. Jun G, Nicolaou M, Morrison MA, Kim IK, Schaumberg DA, Kotoula MG, Tsroni EE, Zacharaki F, Hageman GS, Farrer LA, DeAngelis MM (). Gene-Gene Interaction between ROBO1 and RORA in Neovascular Age-related Macular Degeneration. Washington, D.C [Abstract]. The American Society of Human Genetics.
  4. Feehan M, Durante R, Hartman J, DeAngelis M (). Identifying Subtypes of Patients with Neovascular Age-Related Macular Degeneration by Genotypic and Cardiovacular Risk Characteristics. Washington D.C [Abstract]. The American Society of Human Genetics.
  5. Silveira AC, Morrison MA, Miller JW, Kim IK, Schaumberg DA, Hollis BW, Chen R, Hageman GS, DeAngelis MM (). Genetic Data Suggest a Novel Association Between the Vitamin D Pathway and Neovascular Age-Related Macular Degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  6. Jian Seyedahmadi B, Yonekawa Y, Morrison MA, Kim IK, Miller JW, Haider NB, Hageman GS, Farrer LA, June G, DeAngelis MM (). The Roundabout, Axon Gidance Receptor, Homolog 1 (ROBO1), a Potential MOdifier and Therapeutic Target for Early and Intermediate Dry Age-Related Macular Degneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  7. Schaumberg DA, Christen WG, DeAngelis MM, Chasman DI (). Novel Associations of SNPs on Chromosomes 2 and 16 and Risk of Incident Neovascular Age-Related Macular Degeneration in Women's Genome Health Study. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  8. Brown EN, Hancox LS, Miller NJ, Hageman JL, Pappas CM, Hutcheson DA, Morrison MA, Leppert MF, DeAngelis MM, Hageman GS (). Determination and Assessment of Extended Haplotypes Spanning the Chromosome 1q32 CFH-To-CFHR5 Locus. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  9. Jun G, Adams SM, Kim ID, MIller JW, Hageman GS, Kotoula MG, Tsironi EE, Farrer LA, DeAngelis MM (). Extended Analysis in the 10q26 REgion for Neovascular Age-Related Macular Degneration (AMD). Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthallmology.
  10. Wong RK, Yonekawa Y, Sun G, DeAngelis MM, Morrison M, Chiang MF, Lee TC, Chan RVP (). Update: Assisted Conception and Progression of Retinopathy of Prematurity. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  11. Morrison MA, Xu H, Kotoula MG, Tsironi EE, Tsiloulis AN, Schaumberg DA, Kim IK, Miller JW, Ott J, DeAngelis MM (). The Retinoic Acid Receptor-Related Orphan Receptor α Gene (RORA), A Potential Anti-Angiogenic Therapeutic Target for Age-Related Macular Degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  12. Arneberg TM, Morrison MA, Adams SM, Janssian M, Miller JW, Kim IK, DeAngelis MM (). 1q32 and 10q26 Genotypes and Haplotypes Associated With Disease Severity in Age-Related Macular Degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  13. Kim BJ, Andreoli MT, Morrison MA, Adams SM, Miller JW, DeAngelis MM, Kim IK (). Correlation of Advanced Age-Related Macular Degeneration Phenotype With Variants in the LOC387715/ARMS2/HTRA1 Region. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  14. Arneberg TM, Morrison MA, Andreoli MT, Adams SM, Sato H, Xu X, Miller JW, Kim IK, Hoh J, DeAngelis MM (). Alleles in Complement Factor D but Not Complement Factor B or Component 2 Contribute to Risk for Neovascular Age-Related Macular Degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  15. Morrison MA, Zhang HP, Adams SM, Andreoli MT, Huynh N, Miller JW, Kim IK, Hoh J, DeAngelis MM (). Independent Validation of the Nei/Ncbi Dbgap Database: Genotypes and Haplotypes Associated With Risk of Advanced Age-Related Macular Degeneration in a Caucasian Population of European Descent. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  16. Harring AJ, Lane AM, Morrison MA, Capone A, Dryja TP, Miller JW, Kim IK, DeAngelis MM (). UVR exposure and risk of neovascular age-related macular degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  17. Kim IK, Ji F, Adams SM, Morrison MA, Corcoran WD, Sweeny MO, Capone A, Miller JW, Ott J, Dryja TP, DeAngelis MM (). Analysis Of The 1q24-q41 Region And The Candidate Gene RGS13 In Sibling Pairs Extremely Discordant For Neovascular Age-related Macular Degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  18. Adams SM, Ji F, Morrison MA, Corcoran WD, Sweeny MO, Capone A, Miller JW, Ott J, Dryja TP, Kim IK, DeAngelis MM (). HTRA1 Genotypes Associated with Risk Of Neovascular Age-related Macular Degeneration Independent Of CFH And Smoking. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  19. Kim IK, Ji F, Adams S, Capone A, Miller JW, Ott J, Dryja TP, DeAngelis MM (). Analysis of the C-reactive protein gene in sibling pairs extremely discordant for neovascular age-related macular degeneration. New Orleans, LA [Abstract]. The American Society for Human Genetics.
  20. Lane A, Kim I, Morrison M, Harring A, Colbert A, Osentoski T, Capone A, Dryja TP, Miller J, DeAngelis MM (). Hypertension is risk factor for neovascular age–related macular degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  21. Adams SM, Kim IK, Harring AJ, Osentoski T, Capone A, Miller JW, Dryja TP, DeAngelis MM (). Analysis of the C-reactive protein gene in patients with neovascular age–related macular degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  22. Patty LE, Ji F, Kim IK, Reagan M, Adams SM, Morrison M, Dryja TP, Ott J, Miller JW, DeAngelis MM (). Analysis of the TCP-1 Gene (T-Complex polypepetide 1) in patients with neovascular age–related macular degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.
  23. DeAngelis MM, Ji F, Kim IK, Adams SM, Harring AJ, Osentoski T, Capone A, Ott J, Miller JW, Dryja TP (). Independent effects of CFH genotype and smoking history but no effect of APOE and ELOVL4 genotype on risk for neovascular age–related macular degeneration. Fort Lauderdale, FL [Abstract]. The Association for Research in Vision and Ophthalmology.

Video/Film/CD/Web/Podcast

  1. DeAngelis MM (). Utah BioHealth Initiative [Video]. University of Utah.
  2. DeAngelis MM (). Hope and Cope – Living with Macular Degeneration. Video distributed to retinal specialists, libraries, Commissions for the Blind and support groups [Video]. The American Macular Degeneration Foundation.