Cho Y. Lam, PhD

Labs

Lab Website

Languages

  • English

Academic Information

  • Departments: Population Health Sciences - Research Associate Professor
  • Divisions: Health System Innovation and Research

Academic Office Information

  • 801-213-6179
  • Huntsman Cancer Institute
    Population Health Sciences
    2000 Circle of Hope, Room: 4703
    Salt Lake City, UT 84112

Academic Bio

My work focuses on nicotine addiction and smoking cessation. In one line of my work, I use ecological momentary assessment, or EMA, to examine determinants of smoking and smoking relapse. EMA is an assessment method that measures smokers’ experience in real time and in real life. EMA allows us to study when, how, and why smokers smoke or relapse. For example, previous research has shown that smokers are more likely to smoke when they drink. Using EMA, I was able to delineate the mechanism that links drinking and smoking by studying incidents of drinking and smoking in real life. We found that drinking increased smokers’ positive smoking outcome expectancies, which in turn, increased their desire to smoke. In addition to drinking, negative affect and other people smoking around you have also been found to be reliable triggers of smoking. Using EMA, I showed that combining these triggers disproportionately increase smokers’ chance of committing a smoking lapse (1/250 when there is no trigger, ¼ when all 3 triggers are present). Collaborating with Dr. David Wetter, I am adding on-body sensing technologies to this line of research. I have also used EMA to study symptoms of fatigue, sleep, and pain among cancer patients.

I am also interested in studying public health strategies to reduce smoking. For instance, I led a project, Taking Texas Tobacco Free (TTTF), that disseminated and implemented a multi-level, multi-component tobacco-free program to over 250 behavioral health centers across Texas. The multi-level intervention had components that separately targeted the clinic leadership, non-clinical employees, clinical providers to implement tobacco-free campus policy and tobacco cessation training program across the centers. From TTTF, l learned that although patients who suffer from behavioral health disorders have high rates of tobacco use, many clinical providers who provide care to these patients have little or no training on treatments of tobacco cessation. In TTTF2, we use Project ECHO, a tele-mentoring approach, to partner tobacco treatment specialists at a major cancer center with clinical-providers at behavioral health centers so that the specialists can share their knowledge on tobacco use treatments with community providers.

Research Statement

My work focuses on nicotine addiction and smoking cessation. In one line of my work, I use ecological momentary assessment, or EMA, to examine determinants of smoking and smoking relapse. EMA is an assessment method that measures smokers’ experience in real time and in real life. EMA allows us to study when, how, and why smokers smoke or relapse. For example, previous research has shown that smokers are more likely to smoke when they drink. Using EMA, I was able to delineate the mechanism that links drinking and smoking by studying incidents of drinking and smoking in real life. We found that drinking increased smokers’ positive smoking outcome expectancies, which in turn, increased their desire to smoke. In addition to drinking, negative affect and other people smoking around you have also been found to be reliable triggers of smoking. Using EMA, I showed that combining these triggers disproportionately increase smokers’ chance of committing a smoking lapse (1/250 when there is no trigger, ¼ when all 3 triggers are present). Collaborating with Dr. David Wetter, I am adding on-body sensing technologies to this line of research. I have also used EMA to study symptoms of fatigue, sleep, and pain among cancer patients.

I am also interested in studying public health strategies to reduce smoking. For instance, I led a project, Taking Texas Tobacco Free (TTTF), that disseminated and implemented a multi-level, multi-component tobacco-free program to over 250 behavioral health centers across Texas. The multi-level intervention had components that separately targeted the clinic leadership, non-clinical employees, clinical providers to implement tobacco-free campus policy and tobacco cessation training program across the centers. From TTTF, l learned that although patients who suffer from behavioral health disorders have high rates of tobacco use, many clinical providers who provide care to these patients have little or no training on treatments of tobacco cessation. In TTTF2, we use Project ECHO, a tele-mentoring approach, to partner tobacco treatment specialists at a major cancer center with clinical-providers at behavioral health centers so that the specialists can share their knowledge on tobacco use treatments with community providers.

Education History

Type School Degree
Postdoctoral Fellowship University of Texas MD Anderson Cancer Center
Cancer Prevention
Postdoctoral Fellow
Fellowship University of Texas MD Anderson Cancer Center
Cancer Prevention
Predoctoral Fellow
Doctoral Training Binghamton University
Clinical Psychology
Ph.D.
Residency University of Mississippi Medical Center
Psychology
Resident
Graduate Training California State University, Fresno
Psychology
M.A.
Undergraduate University of Manitoba
Psychology
B.A.

Global Impact

Education History

Type School Degree Country
Undergraduate University of Manitoba
Psychology
B.A. Canada

Selected Publications

Journal Article

  1. Spears CA, Li L, Wu C, Vinci C, Heppner WL, Hoover DS, Lam CY, amp Wetter DW (). Mechanisms linking mindfulness and early smoking abstinence: An ecological momentary assessment study. Psychol Addict Behav.
  2. Vinci C, Haslam A, Lam CY, Kumar S, Wetter DW (2018 Aug). The use of ambulatory assessment in smoking cessation. Addict Behav, 83, 18-24.
  3. Cui Y, Engelmann JM, Xian J, Minnix JA, Lam CY, Karam-Hage M, Cinciripini PM, Robinson JD (2018 Jan). Pharmacological intervention and abstinence in smokers undergoing cessation treatment: A psychophysiological study. Int J Psychophysiol, 123, 25-34.
  4. Versace F, Stevens EM, Robinson JD, Cui Y, Deweese MM, Engelmann JM, Green CE, Karam-Hage M, Lam CY, Minnix JA, Wetter DW, Cinciripini PM (2017 Dec 6). Brain Responses to Cigarette-Related and Emotional Images in Smokers During Smoking Cessation: No Effect of Varenicline or Bupropion on the Late Positive Potential.LID - 10.1093/ntr/ntx264 [doi]. (Epub ahead of print) Nicotine Tob Res.
  5. Vinci C, Li L, Wu C, Lam CY, Guo L, Correa-Fernandez V, Spears CA, Hoover DS, Etcheverry PE, Wetter DW (2017 Nov). The association of positive emotion and first smoking lapse: An ecological momentary assessment study. Health Psychol, 36(11), 1038-1046.
  6. Vinci C, Guo L, Spears CA, Li L, Correa-Fernandez V, Etcheverry PE, Lam CY, Hoover DS, Wetter DW (2017 Sep 1). Socioeconomic indicators as predictors of smoking cessation among Spanish-Speaking Mexican Americans. Ethn Health, 1-13.
  7. Samaha HL, Correa-Fernandez V, Lam C, Wilson WT, Kyburz B, Stacey T, Williams T, Reitzel LR (2017 Jul). Addressing Tobacco Use Among Consumers and Staff at Behavioral Health Treatment Facilities Through Comprehensive Workplace Programming. Health Promotion Practice, 18(4), 561-570.
  8. Correa-Fernandez V, Wilson WT, Shedrick DA, Kyburz B, L Samaha H, Stacey T, Williams T, Lam CY, Reitzel LR (2017 Jun). Implementation of a tobacco-free workplace program at a local mental health authority. Transl Behav Med, 7(2), 204-211.
  9. Versace F, Engelmann JM, Deweese MM, Robinson JD, Green CE, Lam CY, Minnix JA, Karam-Hage MA, Wetter DW, Schembre SM, Cinciripini PM (2017 Jun 1). Beyond Cue Reactivity: Non-Drug-Related Motivationally Relevant Stimuli Are Necessary to Understand Reactivity to Drug-Related Cues. Nicotine Tob Res, 19(6), 663-669.
  10. Etcheverry PE, Waters AJ, Lam C, Correa-Fernandez V, Vidrine JI, Cinciripini PM, Wetter DW (2016 Aug). Attentional bias to negative affect moderates negative affect's relationship with smoking abstinence. Health Psychol, 35(8), 881-890.
  11. Aigner CJ, Cinciripini PM, Anderson KO, Baum GP, Gritz ER, Lam CY (2016 Jun). The Association of Pain With Smoking and Quit Attempts in an Electronic Diary Study of Cancer Patients Trying to Quit. Nicotine Tob Res, 18(6), 1449-55.
  12. Cui Y, Tang R, Lam CY, Cinciripini PM, Robinson JD (2016 Mar). The influence of personality traits on smokers' affect, withdrawal and cessation intervention outcome. Addict Behav, 54, 7-11.
  13. Kumar S, Abowd GD, Abraham WT, alAbsi M, Beck JG, Chau DH, Condie T, Conroy DE, Ertin E, Estrin D, Ganesan D, Lam C, Marlin B, Marsh CB, Murphy SA, Nahum-Shani I, Patrick K, Rehg JM, Sharmin M, Shetty V, Sim I, Spring B, Srivastava M, Wetter DW (2015 Nov). Center of excellence for mobile sensor data-to-knowledge (MD2K). J Am Med Inform Assoc, 22(6), 1137-42.
  14. Cui Y, Robinson JD, Engelmann JM, Lam CY, Minnix JA, Karam-Hage M, Wetter DW, Dani JA, Kosten TR, Cinciripini PM (2015 Jun). Reinforcement sensitivity underlying treatment-seeking smokers' affect, smoking reinforcement motives, and affective responses. Psychol Addict Behav, 29(2), 300-311.
  15. Ratcliff CG, Lam CY, Arun B, Valero V, Cohen L (2014 Nov). Ecological momentary assessment of sleep, symptoms, and mood during chemotherapy for breast cancer. Psychooncology, 23(11), 1220-8.
  16. Businelle MS, Ma P, Kendzor DE, Reitzel LR, Chen M, Lam CY, Bernstein I, Wetter DW (2014 Oct). Predicting quit attempts among homeless smokers seeking cessation treatment: an ecological momentary assessment study. Nicotine Tob Res, 16(10), 1371-8.
  17. Cano MA, Lam CY, Chen M, Adams CE, Correa-Fernandez V, Stewart DW, McClure JB, Cinciripini PM, Wetter DW (2014 Aug). Positive smoking outcome expectancies mediate the association between negative affect and smoking urge among women during a quit attempt. Exp Clin Psychopharmacol, 22(4), 332-40.
  18. Ostroff JS, Burkhalter JE, Cinciripini PM, Li Y, Shiyko MP, Lam CY, Hay JL, Dhingra LK, Lord-Bessen J, Holland SM, Manna R (2014 Jul). Randomized trial of a presurgical scheduled reduced smoking intervention for patients newly diagnosed with cancer. Health Psychol, 33(7), 737-47.
  19. Versace F, Engelmann JM, Robinson JD, Jackson EF, Green CE, Lam CY, Minnix JA, Karam-Hage MA, Brown VL, Wetter DW, Cinciripini PM (2014 Jun). Prequit fMRI responses to pleasant cues and cigarette-related cues predict smoking cessation outcome. Nicotine Tob Res, 16(6), 697-708.
  20. Adams CE, Chen M, Guo L, Lam CY, Stewart DW, Correa-Fernandez V, Cano MA, Heppner WL, Vidrine JI, Li Y, Ahluwalia JS, Cinciripini PM, Wetter DW (2014 Jun). Mindfulness predicts lower affective volatility among African Americans during smoking cessation. Psychol Addict Behav, 28(2), 580-5.
  21. Lam CY, Businelle MS, Aigner CJ, McClure JB, Cofta-Woerpel L, Cinciripini PM, Wetter DW (2014 May). Individual and combined effects of multiple high-risk triggers on postcessation smoking urge and lapse. Nicotine Tob Res, 16(5), 569-75.
  22. Watkins KL, Regan SD, Nguyen N, Businelle MS, Kendzor DE, Lam C, Balis D, Cuevas AG, Cao Y, Reitzel LR (2014 May). Advancing cessation research by integrating EMA and geospatial methodologies: associations between tobacco retail outlets and real-time smoking urges during a quit attempt. Nicotine Tob Res, 16 Suppl 2, S93-101.
  23. Kendzor DE, Businelle MS, Reitzel LR, Castro Y, Vidrine JI, Mazas CA, Cinciripini PM, Lam CY, Adams CE, Correa-Fernandez V, Cano MA, Wetter DW (2014 Mar 1). The influence of discrimination on smoking cessation among Latinos. Drug Alcohol Depend, 136, 143-8.
  24. Lam CY, Businelle MS, Cofta-Woerpel L, McClure JB, Cinciripini PM, Wetter DW (2014 Mar). Positive smoking outcome expectancies mediate the relation between alcohol consumption and smoking urge among women during a quit attempt. Psychol Addict Behav, 28(1), 163-72.
  25. Minnix JA, Versace F, Robinson JD, Lam CY, Engelmann JM, Cui Y, Brown VL, Cinciripini PM (2013 Jul). The late positive potential (LPP) in response to varying types of emotional and cigarette stimuli in smokers: a content comparison. Int J Psychophysiol, 89(1), 18-25.
  26. Cui Y, Versace F, Engelmann JM, Minnix JA, Robinson JD, Lam CY, Karam-Hage M, Brown VL, Wetter DW, Dani JA, Kosten TR, Cinciripini PM (2013 May). Alpha oscillations in response to affective and cigarette-related stimuli in smokers. Nicotine Tob Res, 15(5), 917-24.
  27. Cinciripini PM, Robinson JD, Karam-Hage M, Minnix JA, Lam C, Versace F, Brown VL, Engelmann JM, Wetter DW (2013 May). Effects of varenicline and bupropion sustained-release use plus intensive smoking cessation counseling on prolonged abstinence from smoking and on depression, negative affect, and other symptoms of nicotine withdrawal. JAMA Psychiatry, 70(5), 522-33.
  28. Businelle MS, Lam CY, Kendzor DE, Cofta-Woerpel L, McClure JB, Cinciripini PM, Wetter DW (2013 Feb). Alcohol consumption and urges to smoke among women during a smoking cessation attempt. Exp Clin Psychopharmacol, 21(1), 29-37.
  29. Robinson JD, Versace F, Lam CY, Minnix JA, Engelmann JM, Cui Y, Karam-Hage M, Shete SS, Tomlinson GE, Chen TT, Wetter DW, Green CE, Cinciripini PM (2013). The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers. Front Psychiatry, 4, 114.
  30. Novy DM, Lam C, Gritz ER, Hernandez M, Driver LC, Koyyalagunta D (2012). Distinguishing features of cancer patients who smoke: pain, symptom burden, and risk for opioid misuse. J Pain, 13(11), 1058-67.
  31. Versace F, Lam CY, Engelmann JM, Robinson JD, Minnix JA, Brown VL, Cinciripini PM (2012). Beyond cue reactivity: blunted brain responses to pleasant stimuli predict long-term smoking abstinence. Addict Biol, 17(6), 991-1000.
  32. Cui Y, Robinson JD, Versace F, Lam CY, Minnix JA, Karam-Hage M, Dani JA, Kosten TR, Wetter DW, Brown VL, Cinciripini PM (2012). Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers. Addict Behav, 37(8), 885-9.
  33. Lam CY, Robinson JD, Versace F, Minnix JA, Cui Y, Carter BL, Wetter DW, Cinciripini PM (2012 Apr). Affective reactivity during smoking cessation of never-quitters as compared with that of abstainers, relapsers, and continuing smokers. Exp Clin Psychopharmacol, 20(2), 139-50.
  34. Engelmann JM, Versace F, Robinson JD, Minnix JA, Lam CY, Cui Y, Brown VL, Cinciripini PM (2012 Mar). Neural substrates of smoking cue reactivity: a meta-analysis of fMRI studies. Neuroimage, 60(1), 252-62.
  35. Robinson JD, Lam CY, Carter BL, Wetter DW, Cinciripini PM (2012 Jan 1). Negative reinforcement smoking outcome expectancies are associated with affective response to acute nicotine administration and abstinence. Drug Alcohol Depend, 120(1-3), 196-201.
  36. Versace F, Engelmann JM, Jackson EF, Costa VD, Robinson JD, Lam CY, Minnix JA, Brown VL, Wetter DW, Cinciripini PM (2011 Dec). Do brain responses to emotional images and cigarette cues differ? An fMRI study in smokers. Eur J Neurosci, 34(12), 2054-63.
  37. Versace F, Minnix JA, Robinson JD, Lam CY, Brown VL, Cinciripini PM (2011 Apr). Brain reactivity to emotional, neutral and cigarette-related stimuli in smokers. Addict Biol, 16(2), 296-307.
  38. Robinson JD, Lam CY, Carter BL, Minnix JA, Cui Y, Versace F, Wetter DW, Cinciripini PM (2011 Feb). A multimodal approach to assessing the impact of nicotine dependence, nicotine abstinence, and craving on negative affect in smokers. Exp Clin Psychopharmacol, 19(1), 40-52.
  39. Blalock JA, Lam CY, Minnix JA, Karam-Hage M, Gritz ER, Robinson JA, Cinciripini PM (). The effect of mood, anxiety and alcohol use disorders on smoking cessation in cancer patients. J Cognit Psychother, 25(1), 82-96.
  40. Minnix JA, Robinson JD, Lam CY, Carter BL, Foreman JE, Vandenbergh DJ, Tomlinson GE, Wetter DW, Cinciripini PM (2011 Jan). The serotonin transporter gene and startle response during nicotine deprivation. Biol Psychol, 86(1), 1-8.
  41. Versace F, Robinson JD, Lam CY, Minnix JA, Brown VL, Carter BL, Wetter DW, Cinciripini PM (2010 May 1). Cigarette cues capture smokers' attention: evidence from event-related potentials. Psychophysiology, 47(3), 435-41.
  42. Carter BL, Paris MM, Lam CY, Robinson JD, Traylor AC, Waters AJ, Wetter DW, Cinciripini PM (2010 Mar-Apr). Real-time craving differences between black and white smokers. Am J Addict, 19(2), 136-40.
  43. Cinciripini PM, Blalock JA, Minnix JA, Robinson JD, Brown VL, Lam C, Wetter DW, Schreindorfer L, McCullough JP, Dolan-Mullen P, Stotts AL, Karam-Hage M (2010 Feb). Effects of an intensive depression-focused intervention for smoking cessation in pregnancy. J Consult Clin Psychol, 78(1), 44-54.
  44. Zevallos JP, Mallen MJ, Lam CY, Karam-Hage M, Blalock J, Wetter DW, Garden AS, Sturgis EM, Cinciripini PM (2009 Oct 1). Complications of radiotherapy in laryngopharyngeal cancer: effects of a prospective smoking cessation program. Cancer, 115(19), 4636-44.
  45. Waters AJ, Carter BL, Robinson JD, Wetter DW, Lam CY, Kerst W, Cinciripini PM (2009 Aug). Attentional bias is associated with incentive-related physiological and subjective measures. Exp Clin Psychopharmacol, 17(4), 247-57.
  46. Carter BL, Lam CY, Robinson JD, Paris MM, Waters AJ, Wetter DW, Cinciripini PM (2009 Jul). Generalized craving, self-report of arousal, and cue reactivity after brief abstinence. Nicotine Tob Res, 11(7), 823-6.
  47. Lam CY, Robinson JD, Carter BL, Wetter DW, Minnix JA, Cinciripini PM (2008 Dec). Nicotine differentially inhibits the acoustic startle reflex in African American and Caucasian American smokers. Addict Behav, 33(12), 1521-8.
  48. Carter BL, Lam CY, Robinson JD, Paris MM, Waters AJ, Wetter DW, Cinciripini PM (2008 Jul). Real-time craving and mood assessments before and after smoking. Nicotine Tob Res, 10(7), 1165-9.
  49. Waters AJ, Carter BL, Robinson JD, Wetter DW, Lam CY, Cinciripini PM (2007 Dec 1). Implicit attitudes to smoking are associated with craving and dependence. Drug Alcohol Depend, 91(2-3), 178-86.
  50. Robinson JD, Cinciripini PM, Carter BL, Lam CY, Wetter DW (2007 Aug). Facial EMG as an index of affective response to nicotine. Exp Clin Psychopharmacol, 15(4), 390-9.
  51. Robinson JD, Lam CY, Minnix JA, Wetter DW, Tomlinson GE, Minna JD, Chen TT, Cinciripini PM (2007 Aug). The DRD2 TaqI-B polymorphism and its relationship to smoking abstinence and withdrawal symptoms. Pharmacogenomics J, 7(4), 266-74.
  52. Robinson JD, Cinciripini PM, Tiffany ST, Carter BL, Lam CY, Wetter DW (2007 Mar). Gender differences in affective response to acute nicotine administration and deprivation. Addict Behav, 32(3), 543-61.
  53. Cinciripini PM, Robinson JD, Carter BL, Lam C, Wu X, de Moor CA, Baile WF, Wetter DW (2006 Jun). The effects of smoking deprivation and nicotine administration on emotional reactivity. Nicotine Tob Res, 8(3), 379-92.
  54. Carter BL, Robinson JD, Lam CY, Wetter DW, Tsan JY, Day SX, Cinciripini PM (2006 Jun). A psychometric evaluation of cigarette stimuli used in a cue reactivity study. Nicotine Tob Res, 8(3), 361-9.
  55. Cinciripini PM, Tsoh JY, Wetter DW, Lam C, de Moor C, Cinciripini L, Baile W, Anderson C, Minna JD (2005 Nov). Combined effects of venlafaxine, nicotine replacement, and brief counseling on smoking cessation. Exp Clin Psychopharmacol, 13(4), 282-92.
  56. Lam CY, Pepper CM, Ryabchenko KA (2004 Winter). Case identification of mood disorders in Asian American and Caucasian American college students. Psychiatr Q, 75(4), 361-73.

Review

  1. Lam CY, Gritz ER (). Incorporating behavioral research to examine the relationship between betel quid chewing and oral cancer in Taiwan. [Review]. Biomedicine, 2(4), 160-6.
  2. Lam CY, Minnix JA, Robinson JD, Cinciripini PM (2006 Jul). A brief review of pharmacotherapies for smoking cessation. [Review]. J Natl Compr Canc Netw, 4(6), 583-9.

Book Chapter

  1. Gritz ER, Lam CY, Vidrine DJ, Fingeret MC (). Cancer prevention: Tobacco dependence and its treatment. In DeVita VT, Lawrence TS, Rosenberg SA (Eds.), Cancer: Principles and Practice of Oncology (8th Edition, pp. 593-607). Philadelphia, PA: Lippincott Williams & Wilkins.