Sheetal Hardikar, PhD, MBBS

Research Interests

  • Identifying and Evaluating Novel Molecular and Genetic Biomarkers for Cancer Risk and Prognosis of Gastrointestinal Cancers
  • The Role of Inflammation in Development, Prevention, and Progression of Gastrointestinal Cancers
  • Chronic Conditions Related to Inflammation, Including Obesity and Diabetes, and Their Role in the Development and Progression of Gastrointestinal Cancers
  • Cancer Screening Through Risk Stratification

Languages

  • English
  • Hindi
  • Marathi

Academic Information

  • Departments: Population Health Sciences - Assistant Professor
  • Divisions: Cancer Population Science

Academic Office Information

  • 801-213-6238
  • Huntsman Cancer Institute
    2000 Circle of Hope, Room: Room 4711
    Salt Lake City, UT 84112

Education History

Type School Degree
Research Fellow Fred Hutchinson Cancer Research Center
Cancer Prevention
Postdoctoral Research Fellow
Doctoral Training University of Washington School of Public Health
Epidemiology
Ph.D.
Graduate Training Ohio State University College of Public Health
Biostatistics
M.P.H.
Graduate Training Ohio State University College of Public Health
Epidemiology
M.S.
Professional Medical Maharashtra University of Health Sciences/TN Medical College & BYL Nair Charitable Hospital
Medicine
M.B.B.S.

Global Impact

Education History

Type School Degree Country
Professional Medical Maharashtra University of Health Sciences/TN Medical College & BYL Nair Charitable Hospital
Medicine
M.B.B.S. India

Selected Publications

Journal Article

  1. Himbart C, Ose J, Nattenmuller J, Warby C, Bohm J, Lin T, Holowatyj A, Haffa M, Gigic B, Hardikar S, Scherer D, Zielske L, Schrotz-King P, Kolsch T, Siegel E, Shibata D, Ulrich A, Schneider M, Hursting SD, Kauczor H, Ulrich CM (). Body fatness, adipose tissue compartments and biomarkers of inflammation and angiogenesis in colorectal cancer; the ColoCare Study. Cancer Epidemiol Biomarkers Prev.
  2. Kocarnik JM, Chun KA, Hardikar S, Robinson J, Berndt SI, Chan AT, Figueiredo JC, Lindor NM, Song M, Schoen RE, Hayes RB, Potter JD, Nassir R, Bezieau S, Le Marchand L, Slattery ML, White E, Peters U, Newcomb PA (). Sex-stratified associations of leptin gene variants with colorectal cancer. PLoS ONE.
  3. Citronberg JS, Hardikar S, Phipps A, Figueiredo JC, Newcomb P (2018 Oct). Laxative type in relation to colorectal cancer risk. Ann Epidemiol, 28(10), 739-741.
  4. Dashti SG, Win AK, Hardikar SS, Glombicki SE, Mallenahalli S, Thirumurthi S, Peterson SK, You YN, Buchanan DD, Figueiredo JC, Campbell PT, Gallinger S, Newcomb PA, Potter JD, Lindor NM, Le Marchand L, Haile RW, Hopper JL, Jenkins MA, Basen-Engquist KM, Lynch PM, Pande M (2018 Jun 14). Physical activity and the risk of colorectal cancer in Lynch syndrome.LID - 10.1002/ijc.31611 [doi]. (Epub ahead of print) Int J Cancer.
  5. Phipps AI, Shi Q, Zemla TJ, Dotan E, Gill S, Goldberg RM, Hardikar S, Jahagirdar B, Limburg PJ, Newcomb PA, Shields A, Sinicrope FA, Sargent DJ, Alberts SR (2018 Jun). Physical Activity and Outcomes in Patients with Stage III Colon Cancer: A Correlative Analysis of Phase III Trial NCCTG N0147 (Alliance). Cancer Epidemiol Biomarkers Prev, 27(6), 696-703.
  6. Hardikar S, Burnett-Hartman AN, Phipps AI, Upton MP, Zhu LC, Newcomb PA (2018 May 2). Telomere length differences between colorectal polyp subtypes: a colonoscopy-based case-control study. BMC Cancer, 18(1), 513.
  7. Kocarnik JM, Hua X, Hardikar S, Robinson J, Lindor NM, Win AK, Hopper JL, Figueiredo JC, Potter JD, Campbell PT, Gallinger S, Cotterchio M, Adams SV, Cohen SA, Phipps AI, Newcomb PA (2017 Dec 1). Long-term weight loss after colorectal cancer diagnosis is associated with lower survival: The Colon Cancer Family Registry. Cancer, 123(23), 4701-4708.
  8. Hua X, Phipps AI, Burnett-Hartman AN, Adams SV, Hardikar S, Cohen SA, Kocarnik JM, Ahnen DJ, Lindor NM, Baron JA, Newcomb PA (2017 Aug 20). Timing of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients With Colorectal Cancer in Relation to Tumor Markers and Survival. J Clin Oncol, 35(24), 2806-2813.
  9. Robinson JR, Newcomb PA, Hardikar S, Cohen SA, Phipps AI (2017 Jun). Stage IV colorectal cancer primary site and patterns of distant metastasis. Cancer Epidemiol, 48, 92-95.
  10. Hardikar S, Burnett-Hartman AN, Chubak J, Upton MP, Zhu LC, Potter JD, Newcomb PA (2017 Mar). Reproductive factors and risk of colorectal polyps in a colonoscopy-based study in western Washington State. Cancer Causes Control, 28(3), 241-246.
  11. Hardikar S, Johnson LG, Malkki M, Petersdorf EW, Galloway DA, Schwartz SM, Madeleine MM (2015 Oct). A population-based case-control study of genetic variation in cytokine genes associated with risk of cervical and vulvar cancers. Gynecol Oncol, 139(1), 90-6.
  12. Hardikar S, Newcomb PA, Campbell PT, Win AK, Lindor NM, Buchanan DD, Makar KW, Jenkins MA, Potter JD, Phipps AI (2015 Jul). Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics. Cancer Epidemiol Biomarkers Prev, 24(7), 1130-7.
  13. Hardikar S, Song X, Risques RA, Montine TJ, Duggan C, Blount PL, Reid BJ, Anderson GL, Kratz M, White E, Vaughan TL (2015). Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett's esophagus. BMC Obes, 2, 32.
  14. Hardikar S, Onstad L, Song X, Wilson AM, Montine TJ, Kratz M, Anderson GL, Blount PL, Reid BJ, White E, Vaughan TL (2014 Nov). Inflammation and oxidative stress markers and esophageal adenocarcinoma incidence in a Barrett's esophagus cohort. Cancer Epidemiol Biomarkers Prev, 23(11), 2393-403.
  15. Hardikar S, Song X, Kratz M, Anderson GL, Blount PL, Reid BJ, Vaughan TL, White E (2014 Aug). Intraindividual variability over time in plasma biomarkers of inflammation and effects of long-term storage. Cancer Causes Control, 25(8), 969-76.
  16. Duggan C, Onstad L, Hardikar S, Blount PL, Reid BJ, Vaughan TL (2013 Aug). Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma. Clin Gastroenterol Hepatol, 11(8), 934-43.
  17. Hardikar S, Onstad L, Blount PL, Odze RD, Reid BJ, Vaughan TL (2013). The role of tobacco, alcohol, and obesity in neoplastic progression to esophageal adenocarcinoma: a prospective study of Barrett's esophagus. PLoS ONE, 8(1), e52192.
  18. Fitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Hardikar S, Aviv A (2011 Apr). Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci, 66(4), 421-9.
  19. Ferketich AK, Pirie P, Wewers ME, Barquero D, Hardikar S (). Women and Tobacco Harm Reduction in Appalachia, Ohio. J Smok Cessat, 3(1), 40-6.
  20. Binkley PF, Lesinski A, Ferguson JP, Hatton PS, Yamokoski L, Hardikar S, Cooke GE, Leier CV (2008 Jan). Recovery of normal ventricular function in patients with dilated cardiomyopathy: predictors of an increasingly prevalent clinical event. Am Heart J, 155(1), 69-74.
  21. Burnett-Hartman AN, Chubak J, Hua x, Ziebell R, Kamineni A, Zhu l, Upton MP, Malen RC, Hardikar S, Newcomb PA (). The association between colorectal sessile serrated adenomas/polyps and subsequet advanced colorectal neoplasia. Cancer Causes Control.
  22. Kiblawi R, Holowatyj AN, Gigic B, Brezina S, Geijsen AJMR, Ose J, Lin T, Hardikar S, Himbert C, Warby CA, Bohm J, Bours MJL, van Duijnhoven FJB, Gumpenberger T, Kok DE, Koole JL, van Roekel EH, Schrotz-King P, Ulvik A, Gsur A, Habermann N, Weijenberg MP, Ueland PM, Schneider M, Ulrich A, Ulrich CM, Playdon M (). One-carbon metabolites, B-vitamins and associations with systemic inflammation and angiogenesis biomarkers among colorectal cancer patients: results from the ColoCare Study. Am J Clin Nutr.
  23. Yin H, Hardikar S, Lindstroem S, Hsu L, Anderson A, Banbury B, Berndt SI, Chan AT, Giovanucci EL, Harrison tA, Joshi AD, Nan H, Potter JD, Sakoda LC, Slattery ML, Schoen RE, White E, Peters U, Newcomb PA (). Genetic variation in telomere maintenance genes and survival after colorectal cancer diagnosis. Journal Not Yet Confirmed.
  24. Hardikar S, Li JS, He Q, Kocarnik J, Boyko EJ, Inadomi JM, Newcomb PA (). Association between metformin use and risk of colorectal adenomas: A systematic review and meta-analysis. Journal Not Yet Confirmed.
  25. Hardikar S, Hua X, Phipps AL, Campbell PT, Lindor NM, Figueiredo JC, Buchanan DD, Cotterchio M, Win AK, Ahnen D, Potter JD, Newcomb PA (). Physical activity in relation to overall and colorectal cancer specific survival in the Colon Cancer Family Registry. Journal Not Yet Confirmed.
  26. Holowatyj AN, Lewis MA, Pannier ST, Kirchoff AC, Hardikar S, Figueiredo JC, Shibata D, Schmidt SL, Ulrich CM (). The clinicopathologic heterogeneity of colorectal cancer among adolescents and young adults. Clin Transl Gastroenterol.
  27. Petrick JL, Li N, Anderson LA, Corley DA, El Serag HB, Hardikar S, Liao LM, Liu G, Murray LI, Rubenstein JH, Shaheen NJ, Thrift AP, van den Brandt PA, Vaughan TL, Whiteman DC, Wu AH, Gammon MD, Cook MB (). Diabetes in relation to Barrett's esophagus and esophageal/esophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON Consortium. Cancer.

Conference Proceedings

  1. Burnett-Hartman AN, Hua X, Hardikar S, Kamineni A, Chubak J, Newcomb PA (). The Association between sessile serrated polyps/adenomas and subsequent advanced colorectal neoplasia. Digestive Diseases Week 2018.
  2. Hardikar S, Thomas S, Phipps AI, Newcomb PA (). Differences in leukocyte telomere length, measured using dried blood spot specimens, and survival after colorectal cancer diagnosis. 42nd Annual Meeting of the American society of Preventive Oncology.
  3. Kocarnik JM, Hua X, Hardikar S, Robinson J, Newcomb PA (). Patterns of multivitamin use after colorectal cancer diagnosis in association with long-term survival. 41st Annual Meeting of the American Society of Preventive Oncology, Seattle, WA.
  4. Hardikar S, Onstad L, Blount PL, Reid PJ, Vaughan TL (). Association of systemic markers of chronic inflammation & oxidative stress with esophageal adenocarcinoma in a cohort of Barrett's esophags patients. 10th Annual AACR Conference - Frontiers in Cancer Prevention Research, Boston, MA.