C. Matthew Peterson

C. Matthew Peterson, MD

Languages spoken: English, Japanese

Academic Information

Departments Emeritus -

Divisions:

Academic Office Information

c.matthew.peterson@hsc.utah.edu

Research Interests

  • HPMA copolymer delivered chemotherapy and photosensitizers for the treatment of ovarian cancer
  • Targeting mechanisms to enhance drug delivery and efficacy
  • Reproductive toxicology
  • In Vitro Fertilization
  • Heredity of Common Gynecologic Disorders- PCOS, Endometriosis, Fibroids, Infertility Disorders, Male Factor Infertility
  • Ovarian Biology and Epigenetic Modifications
  • Effects of Environmental Exposures on Reproduction
  • Predictive Preclinical Models of Cancer
  • Novel Treatments for Gynecologic Malignancies

Matthew Peterson, M.D., is a Reproductive Endocrinologist in the University of Utah Department of Obstetrics and Gynecology. Dr. Peterson received his undergraduate degree, magna cum laude from Brigham Young University in 1977 and his M.D. from the University of Utah in 1981. His residency training in obstetrics and gynecology was accomplished at Maricopa Medical Center in Phoenix, Arizona. He stayed on as a faculty member for two years and then completed a fellowship in reproductive endocrinology and infertility at the University of Miami in Florida. He joined the University of Utah in 1989 and serves as the John A. Dixon Presidential Professor and Chair of the Department of Obstetrics and Gynecology.

His clinical research interests include genetic associations and current treatment options in polycystic ovarian syndrome, endometriosis and mullerian anomalies. He was the principal investigator for the NIH’s largest prospective evaluation of environmental chemical exposures and endometriosis, the ENDO study. In addition to the endocrine disruptors being identified, the ENDO study has also elucidated facts regarding the natural history, diagnosis and outcomes associated with endometriosis.

For over 20 years, Dr. Peterson has collaborated with researchers in the Department of Pharmaceutics and Pharmaceutical Chemistry in the development of novel drug delivery systems for the treatment of ovarian cancer. These activities are designed to improve the specificity of treatment and reduce nonspecific toxicity in order to increase response and survival in women facing this cancer. His expertise in these activities involves the design and testing of appropriate ovarian cancer models.

Clinically, Dr. Peterson has an active clinical practice in reproductive endocrinology and accepts new patients. He is the co-editor of Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice. As Practice Director of the in vitro fertilization program at the Utah Center for Reproductive Medicine, he is proud of the excellent patient satisfaction and success rates that significantly exceed national statistics.

He and his wife have five children. His family enjoys snow skiing, water skiing, and dirt bike riding.

Education History

Fellowship University of Miami - School of Medicine
 Fellow
Maricopa Medical Center
 Resident
Internship University of Utah Hospital
 Intern
University of Utah
 MD
Undergraduate Brigham Young University
 BS

Selected Publications

Journal Article

  1. Sadekar S, Ray A, Janat-Amsbury M, Peterson CM, Ghandehari H (2011). Correction to Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice. Biomacromolecules.
  2. Liu L, Milroy C, Peterson CM, Carrell DT (2011). Successful cryoloop vitrification and subsequent in vitro maturation of mouse preantral follicles. Syst Biol Reprod Med, 57(3), 149-53.
  3. Milroy C, Liu L, Hammoud S, Hammoud A, Peterson CM, Carrell DT (2011). Differential methylation of pluripotency gene promoters in in vitro matured and vitrified, in vivo-matured mouse oocytes. Fertil Steril, 95(6), 2094-9.
  4. Arnida, Janat-Amsbury MM, Ray A, Peterson CM, Ghandehari H (2011). Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages. Eur J Pharm Biopharm, 77(3), 417-23.
  5. Sadekar S, Ray A, Janat-Amsbury M, Peterson CM, Ghandehari H (2011). Comparative biodistribution of PAMAM dendrimers and HPMA copolymers in ovarian-tumor-bearing mice. Biomacromolecules, 12(1), 88-96.
  6. Buck Louis GM, Coomey M, Peterson CM (2011). The Ovarian Dysgenesis Syndrome. J Dev Orig Health Dis, (2011).
  7. Hammoud AO, Griffin J, Meikle AW, Gibson M, Peterson CM, Carrell DT (2010). Association of aromatase (TTTAn) repeat polymorphism length and the relationship between obesity and decreased sperm concentration. Hum Reprod, 25(12), 3146-51.
  8. Hammoud A, Carrell DT, Gibson M, Sanderson M, Parker-Jones K, Peterson CM (2010). Decreased sperm motility is associated with air pollution in Salt Lake City. Fertil Steril, 93(6), 1875-9.
  9. Nanassy L, Peterson CA, Wilcox AL, Peterson CM, Hammoud A, Carrell DT (2010). Comparison of 5% and ambient oxygen during days 3-5 of in vitro culture of human embryos. Fertil Steril, 93(2), 579-85.
  10. Mikuni M, Mitsube K, Peterson CM, Brnnstrm M (2009). Glucocorticoid suppression of intraovarian levels of prostaglandins and plasminogen activator activity at ovulation in the rat ovary. J Obstet Gynaecol Res, 35(6), 1005-11.
  11. Gao SQ, Sun Y, Kopeckova P, Peterson CM, Kopecek J (2009). Antitumor efficacy of colon-specific HPMA copolymer/9-aminocamptothecin conjugates in mice bearing human-colon carcinoma xenografts. Macromol Biosci, 9(11), 1135-42.
  12. Liu L, Milroy C, Peterson CM, Carrell DT (2009). Efficient vitrification of Mouse preantral follicles. J Assist Reprod Genet, (2009).
  13. Huang I, Emery BR, Christensen GL, Griffin J, Peterson CM, Carrell DT (2008). Novel UBE2B-associated polymorphisms in an azoospermic/oligozoospermic population. Asian J Androl, 10(3), 461-6.
  14. Hammoud AO, Gibson M, Peterson CM, Kerber RA, Mineau GP, Hatasaka H (2008). Quantification of the familial contribution to mullerian anomalies. Obstet Gynecol, 111(2 Pt 1), 378-84.
  15. Gao SQ, Sun Y, Kopeckova P, Peterson CM, Kopecek J (2008). Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats. Pharm Res, 25(1), 218-26.

Review

  1. Hammoud AO, Gibson M, Peterson CM, Meikle AW, Carrell DT (2008). Impact of male obesity on infertility: a critical review of the current literature. [Review]. Fertil Steril, 90(4), 897-904.
  2. Aston KI, Peterson CM, Carrell DT (2008). Monozygotic twinning associated with assisted reproductive technologies: a review. [Review]. Reproduction, 136(4), 377-86.