Grant W. Cannon

Grant W. Cannon, MD

Languages spoken: English, French

Academic Information

Departments Emeritus - Internal Medicine

Divisions: Rheumatology

Board Certification

  • American Board of Internal Medicine (Internal Medicine)
  • American Board of Internal Medicine (Sub: Rheumatology)

Grant W. Cannon is Professor of Medicine, Division of Rheumatology, University of Utah and Associate Chief of Staff for Academic Affiliations at the VA Salt Lake City Health Care System.


He received his education and postgraduate training at the University of Utah, completing his Doctor of Medicine Degree in 1979, Internal Medicine Residency in 1982, and Rheumatology Fellowship in 1984.

His work has focused on clinical trials of anti-rheumatic drugs and basic science research in animal models of arthritis. Clinical research involved participation in multi-centered clinical trials of rheumatoid arthritis, osteoarthritis, and seronegative spondyloarthropathies. His most recent work has evaluated patients with rheumatoid arthritis in the VA rheumatoid arthritis (VARA) registry. Dr. Cannon has merged data from the VARA registry with VA administrative databases to evaluate pharmacoepidemiology issues and drug adherence in these patients.

Research Statement

Dr. Cannon’s work has focused on clinical trials of anti-rheumatic drugs and basic science research in animal models of arthritis. Clinical research involved participation in multi-centered clinical trials of rheumatoid arthritis, osteoarthritis, and seronegative spondyloarthropathies. His most recent work has evaluated patients with rheumatoid arthritis in the VA rheumatoid arthritis (VARA) registry. Dr. Cannon has merged data from the VARA registry with VA administrative databases to evaluate pharmacoepidemiology issues and drug adherence in these patients.

Education History

Fellowship University of Utah School of Medicine
 Fellow
University of Utah School of Medicine
 Resident
Internship University of Utah School of Medicine
 Intern
University of Utah Hospital School of Medicine
 MD
Undergraduate University of Utah
 BA

Selected Publications

Journal Article

  1. Aripova N, Thiele GM, Duryee MJ, Hunter CD, Yang Y, Roul P, Ascherman DP, Matson SM, Kunkel G, Cannon GW, Wysham KD, Kerr GS, Monach PA, Baker JF, Poole JA, Mikuls TR, England BR (2024). Antibodies to Malondialdehyde-Acetaldehyde Adduct Are Associated with Prevalent and Incident Rheumatoid Arthritis-Associated Interstitial Lung Disease in U.S. Veterans. Arthritis Rheumatol. (Read full article)
  2. Song S, England BR, Sauer B, George MD, Riley TR, Wallace B, Cannon GW, Mikuls TR, Baker JF (2024). Changes in Characteristics of Patients Initiating and Discontinuing Advanced Therapies for Rheumatoid Arthritis Following the Release of Safety Data. Arthritis Care Res (Hoboken), 76(4), 463-469. (Read full article)
  3. Luedders BA, Wheeler AM, Ascherman DP, Baker JF, Duryee MJ, Yang Y, Roul P, Wysham KD, Monach P, Reimold A, Kerr GS, Kunkel G, Cannon GW, Poole JA, Thiele GM, Mikuls TR, England BR (2024). Plasma Matrix Metalloproteinase Concentrations and Risk of Interstitial Lung Disease in a Prospective Rheumatoid Arthritis Cohort. Arthritis Rheumatol. (Read full article)
  4. Wheeler AM, Baker JF, Riley T, Yang Y, Roul P, Wysham KD, Cannon GW, Kunkel G, Kerr G, Ascherman DP, Monach P, Reimold A, Poole JA, Merriman TR, Mikuls TR, England BR (2024). Development and Internal Validation of a Clinical and Genetic Risk Score for Rheumatoid Arthritis-Associated Interstitial Lung Disease. Rheumatology (Oxford). (Read full article)
  5. Baker JF, England BR, Wysham KD, Sauer B, Joseph AM, Lenert A, Roul P, Xiao R, Gillcrist R, Johnson T, Cannon GW, Duryee M, Thiele GM, Mikuls TR (2024). Associations between Adiponectin and the Development of Diabetes in Rheumatoid Arthritis. J Clin Endocrinol Metab. (Read full article)
  6. England BR, Roul P, Yang Y, Hershberger D, Sayles H, Rojas J, Cannon GW, Sauer BC, Curtis JR, Baker JF, Mikuls TR (2023). Extracting forced vital capacity from the electronic health record through natural language processing in rheumatoid arthritis-associated interstitial lung disease. Pharmacoepidemiol Drug Saf, 33(1), e5744. (Read full article)
  7. Poole JA, England BR, Sayles H, Johnson TM, Duryee MJ, Hunter CD, Baker JF, Kerr GS, Kunkel G, Cannon GW, Sauer BC, Wysham KD, Joseph AM, Wallace BI, Thiele GM, Mikuls TR (2023). Serum alarmins and the risk of incident interstitial lung disease in rheumatoid arthritis. Rheumatology (Oxford). (Read full article)
  8. Jeong S, George MD, Mikuls TR, England BR, Sauer B, Cannon GW, Baker JF (2023). Changes in Patterns of Use of Advanced Therapies Following Emerging Data About Adverse Events in Patients With Rheumatoid Arthritis From the Veterans Affairs Health System. ACR Open Rheumatol, 5(10), 563-567. (Read full article)
  9. Wallace BI, England BR, Baker JF, Rojas J, Sauer BC, Roul P, Kunkel GA, Braaten TJ, Petro A, Mikuls TR, Cannon GW (2023). Lowering Expectations: Glucocorticoid Tapering Among Veterans With Rheumatoid Arthritis Achieving Low Disease Activity on Stable Biologic Therapy. ACR Open Rheumatol, 5(9), 437-442. (Read full article)
  10. Johnson TM, Mahabir CA, Yang Y, Roul P, Goldsweig AM, Binstadt BA, Baker JF, Sauer BC, Cannon GW, Mikuls TR, England BR (2023). Aortic Stenosis Risk in Rheumatoid Arthritis. JAMA Intern Med, 183(9), 973-81. (Read full article)
  11. Dutt S, Roul P, Yang Y, Johnson TM, Michaud K, Sauer B, Cannon GW, Baker JF, Curtis JR, Mikuls TR, England BR (2023). Multimorbidity Patterns and Rheumatoid Arthritis Disease Outcomes: Findings From a Multicenter, Prospective Cohort. Arthritis Care Res (Hoboken). (Read full article)
  12. Luedders BA, Cope BJ, Hershberger D, DeVries M, Campbell WS, Campbell J, Roul P, Yang Y, Rojas J, Cannon GW, Sauer BC, Baker JF, Curtis JR, Mikuls TR, England BR (2023). Enhancing the identification of rheumatoid arthritis-associated interstitial lung disease through text mining of chest computerized tomography reports. Semin Arthritis Rheum, 60, 152204. (Read full article)
  13. Wheeler AM, Roul P, Yang Y, Brittan KM, Sayles H, Singh N, Sauer BC, Cannon GW, Baker JF, Mikuls TR, England BR (2022). Risk of Prostate Cancer in US Veterans With Rheumatoid Arthritis. Arthritis Care Res (Hoboken), 75(4), 785-792. (Read full article)
  14. Dolomisiewicz A, Ali H, Roul P, Yang Y, Cannon GW, Sauer B, Baker JF, Mikuls TR, Michaud K, England BR (2023). Updating and Validating the Rheumatic Disease Comorbidity Index to Incorporate ICD-10-CM Diagnostic Codes. Arthritis Care Res (Hoboken), 75(10), 2199-2206. (Read full article)
  15. Wheeler AM, Baker JF, Poole JA, Ascherman DP, Yang Y, Kerr GS, Reimold A, Kunkel G, Cannon GW, Wysham KD, Singh N, Lazaro D, Monach P, Bridges SL Jr, Mikuls TR, England BR (2022). Genetic, social, and environmental risk factors in rheumatoid arthritis-associated interstitial lung disease. Semin Arthritis Rheum, 57, 152098. (Read full article)
  16. Johnson TM, Yang Y, Roul P, Sauer BC, Cannon GW, Kunkel G, Michaud K, Baker JF, Mikuls TR, England BR (2022). A Narrowing Mortality Gap: Temporal Trends of Cause-Specific Mortality in a National Matched Cohort Study in US Veterans With Rheumatoid Arthritis. Arthritis Care Res (Hoboken). (Read full article)
  17. Mulcaire-Jones E, Barker AM, Beck JP, Lawrence P, Cannon GW, Battistone MJ (2022). Impact of a Musculoskeletal "Mini-Residency" Professional Development Program on Knee Magnetic Resonance Imaging Orders by Primary Care Providers. J Clin Rheumatol, 28(5), 245-249. (Read full article)
  18. ODell JR, Brophy MT, Pillinger MH, Neogi T, Palevsky PM, Wu H, Davis-Karim A, Newcomb JA, Ferguson R, Pittman D, Cannon GW, Taylor T, Terkeltaub R, Cannella AC, England BR, Helget LN, Mikuls TR (2022). Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management. NEJM Evid, 1(3). (Read full article)
  19. England BR, Campany M, Sayles H, Roul P, Yang Y, Ganti AK, Sokolove J, Robinson WH, Reimold AM, Kerr GS, Cannon GW, Sauer BC, Baker JF, Thiele GM, Mikuls TR (2021). Associations of serum cytokines and chemokines with the risk of incident cancer in a prospective rheumatoid arthritis cohort. Int Immunopharmacol, 97, 107719. (Read full article)
  20. Sauer BC, Chen W, Shen J, Accortt NA, Collier DH, Cannon GW (2021). Potential for Major Therapeutic Changes to Produce Significant Clinical Response Across a Broad Range of Disease Activity: An Observational Study of US Veterans With Rheumatoid Arthritis. Arthritis Care Res (Hoboken), 73(7), 964-974. (Read full article)
  21. Ebel AV, Lutt G, Poole JA, Thiele GM, Baker JF, Cannon GW, Gaffo A, Kerr GS, Reimold A, Schwab P, Singh N, Richards JS, Ascherman DP, Mikuls TR, England BR (2021). Association of Agricultural, Occupational, and Military Inhalants With Autoantibodies and Disease Features in US Veterans With Rheumatoid Arthritis. Arthritis Rheumatol, 73(3), 392-400. (Read full article)
  22. Sauer BC, Chen W, Xu Y, Shen J, Accortt NA, Collier DH, Cannon GW (2020). Empirical evidence of disease activity thresholds used to indicate need for major therapeutic change in US veterans with rheumatoid arthritis. Arthritis Res Ther, 22(1), 253. (Read full article)
  23. England BR, Roul P, Mahajan TD, Singh N, Yu F, Sayles H, Cannon GW, Sauer BC, Baker JF, Curtis JR, Mikuls TR (2019). Performance of Administrative Algorithms to Identify Interstitial Lung Disease in Rheumatoid Arthritis. Arthritis Care Res (Hoboken), 72(10), 1392-1403. (Read full article)
  24. Chiou A, England BR, Sayles H, Thiele GM, Duryee MJ, Baker JF, Singh N, Cannon GW, Kerr GS, Reimold A, Gaffo A, Mikuls TR (2020). Coexistent Hyperuricemia and Gout in Rheumatoid Arthritis: Associations With Comorbidities, Disease Activity, and Mortality. Arthritis Care Res (Hoboken), 72(7), 950-958. (Read full article)
  25. Maynard C, Mikuls TR, Cannon GW, England BR, Conaghan PG, stergaard M, Baker DG, Kerr G, George MD, Barton JL, Baker JF (2018). Sex Differences in the Achievement of Remission and Low Disease Activity in Rheumatoid Arthritis. Arthritis Care Res (Hoboken), 72(3), 326-333. (Read full article)
  26. Walsh JA, Pei S, Penmetsa GK, Sauer BC, Patil V, Walker JH, Clewell J, Douglas KM, Clegg DO, Cannon GW, Halwani A (2019). Treatment Patterns with Disease-Modifying Antirheumatic Drugs in U.S. Veterans with Newly Diagnosed Rheumatoid Arthritis, Psoriatic Arthritis, or Ankylosing Spondylitis. J Manag Care Spec Pharm, 25(11), 1218-1228. (Read full article)
  27. Cannon GW, Rojas J, Reimold A, Mikuls TR, Bergman D, Sauer BC (2019). Extraction of Rheumatoid Arthritis Disease Activity Measures From Electronic Health Records Using Automated Processing Algorithms. ACR Open Rheumatol, 1(10), 632-639. (Read full article)
  28. Nelson RE, Ma J, Miller K, Lawrence P, LaFleur J, Grotzke M, Barker A, Cannon GW, Battistone MJ (2019). The impact of a musculoskeletal training program on residents' recognition and treatment of osteoporosis. BMC Med Educ, 19(1), 223. (Read full article)
  29. Cannon GW, Erickson AR, Teng CC, Huynh T, Austin S, Wade SW, Stolshek BS, Collier DH, Mutebi A, Sauer BC (2019). Tumor necrosis factor inhibitor exposure and radiographic outcomes in Veterans with rheumatoid arthritis: a longitudinal cohort study. 3(1).
  30. Cannon GW, Erickson AR, Teng CC, Huynh T, Austin S, Wade SW, Stolshek BS, Collier DH, Mutebi A, Sauer BC (2019). Tumour necrosis factor inhibitor exposure and radiographic outcomes in Veterans with rheumatoid arthritis: a longitudinal cohort study. Rheumatol Adv Pract, 3(1), rkz015. (Read full article)
  31. Keitz SA, Aron DC, Brannen JL, Byrne JM, Cannon GW, Clarke CT, Gilman SC, Hettler DL, Kaminetzky CP, Zeiss RA, Bernett DS, Wicker AB, Kashner TM (2019). Impact of clinical training on recruiting graduating health professionals. Am J Manag Care, 25(4), e111-e118. (Read full article)
  32. Walsh JA, Pei S, Penmetsa G, Hansen JL, Cannon GW, Clegg DO, Sauer BC (2019). Identification of Axial Spondyloarthritis Patients in a Large Dataset: The Development and Validation of Novel Methods. J Rheumatol, 47(1), 42-49. (Read full article)
  33. Davis LA, Cannon GW, Pointer LF, Haverhals LM, Wolff RK, Mikuls TR, Reimold AM, Kerr GS, Richards JS, Johnson DS, Valuck R, Prochazka A, Caplan L (2013). Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis. J Rheumatol, 40(6), 809-17. (Read full article)
  34. Cannon GW, Mikuls TR, Hayden CL, Ying J, Curtis JR, Reimold AM, Caplan L, Kerr GS, Richards JS, Johnson DS, Sauer BC (2011). Merging Veterans Affairs rheumatoid arthritis registry and pharmacy data to assess methotrexate adherence and disease activity in clinical practice. Arthritis Care Res (Hoboken), 63(12), 1680-90. (Read full article)
  35. Kaminetzky CP, Keitz SA, Kashner TM, Aron DC, Byrne JM, Chang BK, Clarke C, Gilman SC, Holland GJ, Wicker A, Cannon GW (2011). Training satisfaction for subspecialty fellows in internal medicine: findings from the Veterans Affairs (VA) Learners' Perceptions Survey. BMC Med Educ, 11, 21. (Read full article)
  36. Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, Johnson D, Richards JS, Kerr GS, Cannon GW, Reimold A (2010). Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry. Rheumatology (Oxford), 50(1), 101-9. (Read full article)
  37. Kerr GS, Sabahi I, Richards JS, Caplan L, Cannon GW, Reimold A, Thiele GM, Johnson D, Mikuls TR (2010). Prevalence of vitamin D insufficiency/deficiency in rheumatoid arthritis and associations with disease severity and activity. J Rheumatol, 38(1), 53-9. (Read full article)
  38. Kashner TM, Byrne JM, Chang BK, Henley SS, Golden RM, Aron DC, Cannon GW, Gilman SC, Holland GJ, Kaminetzky CP, Keitz SA, Muchmore EA, Kashner TK, Wicker AB (2009). Measuring progressive independence with the resident supervision index: empirical approach. J Grad Med Educ, 2(1), 17-30. (Read full article)
  39. Mikuls TR, Gould KA, Bynot KK, Yu F, Levan TD, Thiele GM, Michaud KD, ODell JR, Reimold AM, Hooker R, Caplan L, Johnson DS, Kerr G, Richards JS, Cannon GW, Criswell LA, Noble JA, Bridges SL Jr, Hughes L, Gregersen PK (2010). Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Res Ther, 12(6), R213. (Read full article)
  40. Cannon GW, Keitz SA, Holland GJ, Chang BK, Byrne JM, Tomolo A, Aron DC, Wicker AB, Kashner TM (2008). Factors determining medical students' and residents' satisfaction during VA-based training: findings from the VA Learners' Perceptions Survey. Acad Med, 83(6), 611-20. (Read full article)
  41. Meng HC, Griffiths MM, Remmers EF, Kawahito Y, Li W, Neisa R, Cannon GW, Wilder RL, Gulko PS (2004). Identification of two novel female-specific non-major histocompatibility complex loci regulating collagen-induced arthritis severity and chronicity, and evidence of epistasis. Arthritis Rheum, 50(8), 2695-705. (Read full article)
  42. Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen N, Furst D, Sharp J, Moreland L, Caldwell J, Kaine J, Strand V (2001). Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group. Arthritis Rheum, 44(9), 1984-92. (Read full article)

Review

  1. Williams HJ, Cannon GW, Clegg DO (2023). John R. Ward, MD: Pioneer-Clinical Trials in Rheumatology. [Review]. Rheum Dis Clin North Am, 50(1), 113-121. (Read full article)