Allison H. Payne

Allison H. Payne, PhD

Languages spoken: English

Academic Information

Departments Primary - Radiology & Imaging Sciences

Lab

I am a mechanical engineer with expertise in thermal therapies; specifically magnetic resonance guided focused ultrasound. My research contributes to the translation and dissemination of this exciting technology through the development of new hardware, advanced treatment planning and monitoring and assessment techniques. During the past 10 years, I have led the team that designed a constructed a breast-specific MRgFUS system that is currently in clinical trials in Europe for treating breast cancer. I have additional expertise in mechanical design, MR imaging, temperature measurement, acoustic radiation force imaging and acoustic modeling.

Education History

Undergraduate University of Utah
 BS
Graduate Training University of Utah
 MS
Doctoral Training University of Utah
 PhD
Postdoctoral Fellowship University of Utah
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. Dillon C, Roemer R, Payne A (2015). Magnetic resonance temperature imaging-based quantification of blood flow-related energy losses. NMR Biomed, 28(7), 840-51.
  2. A. Payne, R. Merrill, E. Minalga, J.R. Hadley, H. Odéen, L.W. Hofstetter, S. Johnson, C. Tunon de Lara, S. Auriol, S. Recoo, E. Dumont, D.L. Parker, J. Palussiere (2020). A breast-specific MR guided focused ultrasound platform and treatment protocol: first-in-human technical evaluation. IEEE Trans Biomed Eng, In Press.
  3. Zimmerman B, Johnson S, Odéen H, Shea J, Foote MD, Winkler N, Joshi S, Payne A (2020). Learning multiparametric biomarkers for assessing MR-guided focused ultrasound treatments. IEEE Trans Biomed Eng, In Press.
  4. Hofstetter LW, Fausett L, Mueller A, Odéen H, Payne A, Christensen DA, Parker D (2020). Development and characterization of a tissue mimicking psyllium husk gelatin phantom for ultrasound and magnetic resonance imaging. International journal of hyperthermia, 37(1), 283-290.
  5. Merrill R, Odéen H, Dillon C, Bitton R, Ghanouni P, Payne (2021). Design and evaluation of an open-source, conformable skin-cooling system for body magnetic resonance guided focused ultrasound treatments. International journal of hyperthermia, 38(1), 679-690.
  6. Hansen M, Christensen D, Payne (2021). Experimental validation of acoustic and thermal modeling in heterogeneous phantoms using the hybrid angular spectrum method. International journal of hyperthermia, 38(1), 1617-1626.
  7. Payne A, Vyas U, Todd N, de Bever J, Christensen DA, Parker D (2011). The effect of electronically steering a phased array ultrasound transducer on near-field tissue heating. Medical physics, 38(9), 4971-81.
  8. Payne A, Merrill R, Minalga E, Vyas U, de Bever J, Todd N, Hadley R, Dumont E, Neumayer L, Christensen D, Roemer R, Parker (2012). Design and characterization of a laterally mounted phased-array transducer breast-specific MRgHIFU device with integrated 11-channel receiver array. Medical physics, 39(3), 1552-60.
  9. Payne A, Todd N, Minalga E, Wang Y, Diakite M, Hadley R, Merrill R, Factor R, Neumayer L, Parker D (2013). In vivo evaluation of a breast-specific magnetic resonance guided focused ultrasound system in a goat udder model. Medical physics, 40(7), 073302.
  10. Payne A, de Bever J, Farrer A, Coats B, Parker DL, Christensen D (2015). A simulation technique for 3D MR-guided acoustic radiation force imaging. Medical physics, 42(2), 674-84.
  11. Farrer AI, Almquist S, Dillon CR, Neumayer LA, Parker DL, Christensen DA, Payne (2016). Phase aberration simulation study of MRgFUS breast treatments. Medical physics, 43(3), 1374-84.
  12. Dillon C, Rezvani M, McLean H, Adelman M, Dassel M, Jarboe E, Janát-Amsbury M, Payne (2019). A tissue preparation to characterize uterine fibroid tissue properties for thermal therapies. Medical physics, 46(8), 3344-3355.
  13. Payne A, Minalga E, Merrill R, Parker DL, Hadley J (2020). Technical Note: Effect of transducer position and ground plane configuration on image quality in MR-guided focused ultrasound therapies. Medical physics, 47(6), 2350-2355.
  14. McLean M, Parker DL, Odéen H, Payne (2021). A T1-based correction method for proton resonance frequency shift thermometry in breast tissue. Medical physics, 48(9), 4719-4729.
  15. Payne A, Chopra R, Ellens N, Chen L, Ghanouni P, Sammet S, Diederich C, Ter Haar G, Parker D, Moonen C, Stafford J, Moros E, Schlesinger D, Benedict S, Wear K, Partanen A, Farahani (2021). AAPM Task Group 241: A medical physicist's guide to MRI-guided focused ultrasound body systems. Medical physics, 48(9), e772-e806.
  16. Cross CG, Payne AH, Hawryluk GW, Haag-Roeger R, Cheeniyil R, Brady D, Odéen H, Minoshima S, Cross DJ, Anzai (2021). Technical Note: Quantification of blood-spinal cord barrier permeability after application of magnetic resonance-guided focused ultrasound in spinal cord injury. Medical physics, 48(8), 4395-4401.
  17. Hadley JR, Odéen H, Merrill R, Adams SI, Rieke V, Payne A, Parker D (2021). Improving image quality in transcranial magnetic resonance guided focused ultrasound using a conductive screen. Magnetic resonance imaging, 83, 41-49.
  18. Todd N, Adluru G, Payne A, DiBella EV, Parker (2009). Temporally constrained reconstruction applied to MRI temperature data. Magnetic resonance in medicine, 62(2), 406-19.
  19. Todd N, Diakite M, Payne A, Parker D (2013). Hybrid proton resonance frequency/T1 technique for simultaneous temperature monitoring in adipose and aqueous tissues. Magnetic resonance in medicine, 69(1), 62-70.
  20. Minalga E, Payne A, Merrill R, Todd N, Vijayakumar S, Kholmovski E, Parker DL, Hadley J (2013). An 11-channel radio frequency phased array coil for magnetic resonance guided high-intensity focused ultrasound of the breast. Magnetic resonance in medicine, 69(1), 295-302.
  21. Svedin BT, Payne A, Bolster BD Jr, Parker D (2018). Multiecho pseudo-golden angle stack of stars thermometry with high spatial and temporal resolution using k-space weighted image contrast. Magnetic resonance in medicine, 79(3), 1407-1419.
  22. Hofstetter LW, Odéen H, Bolster BD Jr, Mueller A, Christensen DA, Payne A, Parker D (2019). Efficient shear wave elastography using transient acoustic radiation force excitations and MR displacement encoding. Magnetic resonance in medicine, 81(5), 3153-3167.
  23. Svedin BT, Payne A, Parker D (2019). Simultaneous proton resonance frequency shift thermometry and T1 measurements using a single reference variable flip angle T1 method. Magnetic resonance in medicine, 81(5), 3138-3152.
  24. Dillon CR, Borasi G, Payne (2016). Analytical estimation of ultrasound properties, thermal diffusivity, and perfusion using magnetic resonance-guided focused ultrasound temperature data. Physics in medicine and biology, 61(2), 923-36.
  25. Hofstetter LW, Odeen H, Bolster BD, Christensen D, Payne A, Parker D (2020). Magnetic resonance shear wave elastography using transient acoustic radiation force excitations and sinusoidal displacement encoding. Physics in medicine and biology, 66(5),
  26. Frazier N, Payne A, de Bever J, Dillon C, Panda A, Subrahmanyam N, Ghandehari (2016). High intensity focused ultrasound hyperthermia for enhanced macromolecular delivery. Journal of controlled release, 241, 186-193.
  27. Frazier N, Payne A, Dillon C, Subrahmanyam N, Ghandehari (2017). Enhanced efficacy of combination heat shock targeted polymer therapeutics with high intensity focused ultrasound. Nanomedicine, 13(3), 1235-1243.
  28. Zimmerman BE, Johnson SL, Odéen HA, Shea JE, Factor RE, Joshi SC, Payne A (2021). Histology to 3D in vivo MR registration for volumetric evaluation of MRgFUS treatment assessment biomarkers. Scientific reports, 11(1), 18923.
  29. Koopmann M, Shea J, Kholmovski E, de Bever J, Minalga E, Holbrook M, Merrill R, Hadley JR, Owan T, Salama ME, Marrouche NF, Payne (2016). Renal sympathetic denervation using MR-guided high-intensity focused ultrasound in a porcine model. Journal of therapeutic ultrasound, 4, 3.
  30. Shea J, de Bever J, Kholmovski E, Beal H, Hadley JR, Minalga E, Salama ME, Marrouche NF, Payne (2017). Effect of applied energy in renal sympathetic denervation with magnetic resonance guided focused ultrasound in a porcine model. Journal of therapeutic ultrasound, 5, 16.
  31. Adams-Tew SI, Johnson S, Odéen H, Parker DL, Payne (2023). Validation of a drift-corrected 3D MR temperature imaging sequence for breast MR-guided focused ultrasound treatments. Magnetic resonance imaging, 96, 126-134.
  32. Odéen H, Hofstetter LW, Payne AH, Guiraud L, Dumont E, Parker D (2023). Simultaneous proton resonance frequency T(1) - MR shear wave elastography for MR-guided focused ultrasound multiparametric treatment monitoring. Magnetic resonance in medicine, 89(6), 2171-2185.
  33. Parker DL, Payne A, Odéen (2022). A k-space-based method to measure and correct for temporal B(0) field variations in MR temperature imaging. Magnetic resonance in medicine, 88(3), 1098-1111.
  34. Cornelssen C, Payne A, Parker DL, Alexander M, Merrill R, Senthilkumar S, Christensen J, Wilcox KS, Odéen H, Rolston J (2024). Development of an MR-Guided Focused Ultrasound (MRgFUS) Lesioning Approach for the Fornix in the Rat Brain. Ultrasound in medicine & biology, 50(6), 920-926.
  35. Richards N, Christensen D, Hillyard J, Kline M, Johnson S, Odéen H, Payne (2024). Evaluation of acoustic-thermal simulations of in vivo magnetic resonance guided focused ultrasound ablative therapy. International journal of hyperthermia, 41(1), 2301489.
  36. Nelson CK, Kline M, Payne A, Dillon C (2025). Computational predictions of magnetic resonance acoustic radiation force imaging for breast cancer focused ultrasound therapy. International journal of hyperthermia, 42(1), 2452927.
  37. Richards N, Malmberg M, Odéen H, Johnson S, Kline M, Merrill R, Hadley R, Parker DL, Payne (2025). In vivo simultaneous proton resonance frequency shift thermometry and single reference variable flip angle T(1) measurements. Magnetic resonance in medicine,
  38. Singh A, Adams-Tew S, Johnson S, Odeen H, Shea J, Johnson A, Day L, Pessin A, Payne A, Joshi (2025). Treatment efficacy prediction of focused ultrasound therapies using multi-parametric magnetic resonance imaging. 15199, 190-199.
  39. Shao M, Singh A, Johnson S, Pessin A, Merrill R, Page A, Odéen H, Joshi S, Payne (2024). Design and evaluation of an open-source block face imaging system for 2D histology to magnetic resonance image registration. MethodsX, 13, 103062.
  40. Adams-Tew SI, Odéen H, Parker DL, Cheng CC, Madore B, Payne A, Joshi (2024). Physics Informed Neural Networks for Estimation of Tissue Properties from Multi-echo Configuration State MRI. 15011, 502-511.
  41. Iversen MM, Kline M, Smith EA, Payne A, Shah LM, Rieke (2025). Ablation of cervical facet joints is safe and feasible with two magnetic resonance-guided focused ultrasound transducers as demonstrated by thermal simulations. International journal of hyperthermia, 42(1), 2500487.
  42. Valencia Narva C, Payne A, Dillon C (2026). Integrating temperature-dependent tissue properties into focused ultrasound computational models for enhanced treatment planning. International journal of hyperthermia, 43(1), 2606701.
  43. Rieke V, Payne A, Merrill R, Hadley JR, Odéen H, Kline M, Zabriskie MS, Shah L (2026). Design and evaluation of a magnetic resonance-guided focused ultrasound system for the treatment of cervical spine pain. Medical physics, 53(1), e70221.
  44. Adams-Tew SI, Johnson A, Crockett J, Adams KE, Parker DL, Winkler N, Payne (2026). Impact of breast biopsy markers on magnetic resonance-guided focused ultrasound. International journal of hyperthermia, 43(1), 2632351.

Review

  1. Odéen H, Payne AH, Parker D (2025). Magnetic Resonance Acoustic Radiation Force Imaging (MR-ARFI). Journal of magnetic resonance imaging, 62(1), 20-39.

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