Kathleen M. Job

Kathleen M. Job, PhD, DABCP

Languages spoken: English

Academic Information

Departments Primary - Pediatrics

Divisions: Clinical Pharmacology

Academic Office Information

kate.job@hsc.utah.edu

Board Certification

  • American Board of Clinical Pharmacology

Dr. Kathleen Job is currently a Research Assistant Professor with the Department of Pediatrics, University of Utah School of Medicine, and a delegate of the American Board of Clinical Pharmacology. She earned her PhD in Bioengineering, and subsequently completed the Utah Clinical Pharmacology Fellowship Program. Dr. Job has over 7 years of experience in the design of both drug and device clinical studies in diverse populations.

Dr. Job's clinical research expertise focuses on understanding drug disposition and action from conception through adulthood. Dr. Job's interests are in integrating physiology and pharmacology into approaches for designing, conducting, and interpreting clinical trials.

Research Statement

Dr. Kathleen Job is currently a Research Assistant Professor with the Department of Pediatrics, University of Utah School of Medicine. She earned her PhD at The University of Utah, Salt Lake City, Utah in Bioengineering. She then completed two years of postdoctoral training in Clinical Pharmacology also at The University of Utah. She received board accrediation from the American Board of Clinical Pharmacology in 2018. Dr. Job has experience in the design of both drug and device clinical trials in diverse populations.

Dr. Job's areas of clinical research expertise include the use of drugs and devices in special populations. Dr. Job's interests are in integrating physiology and pharmacology into approaches for designing, conducting, and interpreting clinical trials

Education History

Undergraduate Utah State University
 BS
Undergraduate Utah State University
 BS
Doctoral Training University of Utah
 PhD
Postdoctoral Fellowship University of Utah
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. Enioutina EY, Job KM, Sherwin CM (2020). Why we need to pay attention to toxicity associated with herbal medicines. British journal of clinical pharmacology, 86(9), 1793-1794.
  2. Becker SM, Job KM, Lima K, Forbes TJ, Wagstaff J, Tran NK, Sherwin CM, Nelson DS, Johnson MD, Rower J (2019). Prospective study of serum and ionized magnesium pharmacokinetics in the treatment of children with severe acute asthma. European journal of clinical pharmacology, 75(1), 59-66.
  3. Job KM, Dull RO, Hlady (2012). Use of reflectance interference contrast microscopy to characterize the endothelial glycocalyx stiffness. American journal of physiology. Lung cellular and molecular physiology, 302(12), L1242-9.
  4. Job KM, Roberts JK, Enioutina EY, Illamola SM, Kumar SS, Rashid J, Ward RM, Fukuda T, Sherbotie J, Sherwin C (2021). Treatment optimization of maintenance immunosuppressive agents in pediatric renal transplant recipients. Expert opinion on drug metabolism & toxicology, 17(7), 747-765.
  5. Enioutina EY, Job KM, Krepkova LV, Reed MD, Sherwin C (2020). How can we improve the safe use of herbal medicine and other natural products? A clinical pharmacologist mission. Expert review of clinical pharmacology, 13(9), 935-944.
  6. Illamola SM, Amaeze OU, Krepkova LV, Birnbaum AK, Karanam A, Job KM, Bortnikova VV, Sherwin CMT, Enioutina E (2020). Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know. Frontiers in pharmacology, 10, 1483.
  7. Krepkova LV, Bortnikova VV, Babenko AN, Mizina PG, Mkhitarov VA, Job KM, Sherwin CM, Enioutina E (2021). Effects of a new thyrotropic drug isolated from Potentilla alba on the male reproductive system of rats and offspring development. BMC complementary medicine and therapies, 21(1), 31.
  8. Job KM, Dallmann A, Parry S, Saade G, Haas DM, Hughes B, Berens P, Chen JY, Fu C, Humphrey K, Hornik C, Balevic S, Zimmerman K, Watt (2022). Development of a Generic Physiologically-Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk. Clinical pharmacology and therapeutics, 111(5), 1111-1120.
  9. McKnite AM, Job KM, Nelson R, Sherwin CMT, Watt KM, Brewer S (2022). Medication based machine learning to identify subpopulations of pediatric hemodialysis patients in an electronic health record database. Informatics in medicine unlocked, 34,
  10. Derbalah A, Duffull S, Sherwin CM, Job K, Al-Sallami (2022). Optimal dosing of enoxaparin in overweight and obese children. British journal of clinical pharmacology, 88(12), 5348-5358.
  11. Hudson RE, Metz TD, Ward RM, McKnite AM, Enioutina EY, Sherwin CM, Watt KM, Job K (2023). Drug exposure during pregnancy: Current understanding and approaches to measure maternal-fetal drug exposure. Frontiers in pharmacology,
  12. Constance JE, McFarland MM, Casucci T, Deininger MW, Enioutina EY, Job K, Lemons RS, Lim CS, Ward RM, Yellepeddi V, Watt K (2023). Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review. JMIR research protocols, 12, e38167.
  13. Enioutina EY, Keddington RJ, Hauck KG, Chavez A, Clifford JJ, Cao TA, Smith B, Job KM, Balch (2024). Results of a Pilot Trial Assessing the Effects of Proper Oral Hygiene and a Probiotic Dietary Supplement on Oral Health in Volunteers with Oral Malodor. Microorganisms, 12(9),
  14. Babenko AN, Krepkova LV, Borovkova MV, Kuzina OS, Mkhitarov VA, Job KM, Enioutina E (2024). Effects of Chicory (Cichorium intybus L.) Extract on Male Rat Reproductive System, Pregnancy and Offspring Development. Pharmaceuticals (Basel, Switzerland), 17(6),

Review

  1. Linakis MW, Job KM, Liu X, Collingwood SC, Pangburn HA, Ott DK, Sherwin CM (2017). Riding (High) into the danger zone: a review of potential differences in chemical exposures in fighter pilots resulting from high altitude and G-forces. Expert opinion on drug metabolism & toxicology, 13(9), 925-934.
  2. Enioutina EY, Salis ER, Job KM, Gubarev MI, Krepkova LV, Sherwin C (2017). Herbal Medicines: challenges in the modern world. Part 5. status and current directions of complementary and alternative herbal medicine worldwide. Expert review of clinical pharmacology, 10(3), 327-338.
  3. Krepkova LV, Babenko AN, Saybel' OL, Lupanova IA, Kuzina OS, Job KM, Sherwin CM, Enioutina E (2021). Valuable Hepatoprotective Plants - How Can We Optimize Waste Free Uses of Such Highly Versatile Resources?. Frontiers in pharmacology, 12, 738504.
  4. Sayre CL, Yellepeddi VK ,Job KM, Krepkova LV, Sherwin CMT, Enioutina E (2023). Current use of complementary and conventional medicine for treatment of pediatric patients with gastrointestinal disorders. Frontiers in pharmacology, 14,
  5. Hudson RE, Metz TD, Ward RM, McKnite AM, Enioutina EY, Sherwin CM, Watt KM, Job K (2023). Drug exposure during pregnancy: Current understanding and approaches to measure maternal-fetal drug exposure. Frontiers in pharmacology, 14, 1111601.

Commentary

  1. Job KM, Gamalo M, Ward R (2019). Pediatric Age Groups and Approach to Studies. Therapeutic innovation & regulatory science, 53(5), 584-589.

Editorial

  1. Job KM, Roberts JK, Sherwin C (2023). Editorial: Methods and protocols in obstetric and pediatric pharmacology: 2022. Frontiers in pharmacology, 14, 1205963.