Markus Amann, PhD, MS

Languages spoken: English, German, Latin

Academic Information

Departments: Anesthesiology - Professor, Bioengineering - Adjunct Assistant Professor, Internal Medicine - Adjunct Professor

Divisions: Geriatrics

Academic Office Information

Markus.Amann@hsc.utah.edu

Labs

Research Interests

  • Autonomic Dysfunction
  • Cardiovascular Physiology
  • Fatigue
  • Neurosciences

Dr. Amann is a Professor of Anesthesiology, Theodore H. Stanley Presidential Endowed Chair in Anesthesiology, and Adjunct Professor in the Departments of Internal Medicine and Biomedical Engineering. His research focuses on the neural control of the circulation and breathing, and the etiology of central nervous system fatigue. Dr. Amann’s work aims at enhancing our understanding of the impact of cardiovascular disease on autonomic reflex function and of mechanisms determining neuromuscular fatigue during physical activity. More information about Dr. Amann's research can be found at the Utah Vascular Research Laboratory.

Education History

Postdoctoral Fellowship University of Wisconsin
Pulmonary and Cardiovascular Physiology 		Postdoctoral Fellow
Doctoral Training University of Utah
Integrative Physiology 		Ph.D.
Graduate Training Technical University of Munich
Exercise Physiology 		M.S.

Selected Publications

  1. Hoeppli ME, Thurston TS, Roy M, Light AR, Amann M, Gracely RH, Schweinhardt P (2023). Development of a computerized 2D rating scale for continuous and simultaneous evaluation of two dimensions of a sensory stimulus. Front Psychol, 14, 1127699.
  2. Amann M, Sidhu SK, McNeil CJ, Gandevia SC (2022). Critical considerations of the contribution of the corticomotoneuronal pathway to central fatigue. [Review]. J Physiol.
  3. Weavil JC, Kwon OS, Hughen RW, Zhang J, Light AR, Amann M (2022). Gene and protein expression of dorsal root ganglion sensory receptors in normotensive and hypertensive male rats. Am J Physiol Regul Integr Comp Physiol, 323(2), R221-R226.
  4. Hureau TJ, Broxterman RM, Weavil JC, Lewis MT, Layec G, Amann M (2022). On the role of skeletal muscle acidosis and inorganic phosphates as determinants of central and peripheral fatigue: A 31 P-MRS study. J Physiol, 600(13), 3069-3081.
  5. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Morrissey CK, Amann M (2022). On the haemodynamic consequence of the chemoreflex and muscle mechanoreflex interaction in women and men: two tales, one story. J Physiol, 600, 3671-3688.
  6. Laginestra FG, Cavicchia A, Vanegas-Lopez JE, Barbi C, Martignon C, Giuriato G, Pedrinolla A, Amann M, Hureau TJ, Venturelli M (2022). Prior Involvement of Central Motor Drive does not Impact Performance and Neuromuscular Fatigue in a Subsequent Endurance Task. Med Sci Sports Exerc, 54, 1751-1760.
  7. Venturelli M, Rossman MJ, Ives SJ, Weavil JC, Amann M, Wray DW, Richardson RS (2022). Passive leg movement-induced vasodilation and exercise-induced sympathetic vasoconstriction. Auton Neurosci, 239, 102969.
  8. Weavil JC, Thurston TS, Hureau TJ, Gifford JR, Aminizadeh S, Wan HY, Jenkinson RH, Amann M (2022). Impact of aging on the work of breathing during exercise in healthy men. J Appl Physiol (1985), 132(3), 689-698.
  9. Thurston TS, Weavil JC, Hureau TJ, Gifford JR, Georgescu VP, Wan HY, La Salle DT, Richardson RS, Amann M (2021). On the implication of dietary nitrate supplementation for the hemodynamic and fatigue response to cycling exercise. J Appl Physiol (1985), 131(6), 1691-1700.
  10. Lewis MT, Blain GM, Hart CR, Layec G, Rossman MJ, Park SY, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Jessop JE, Bledsoe AD, Amann M, Richardson RS (2021). Acute high-intensity exercise and skeletal muscle mitochondrial respiratory function: role of metabolic perturbation. Am J Physiol Regul Integr Comp Physiol, 321(5), R687-R698.
  11. Laginestra FG, Amann M, Kirmizi E, Giuriato G, Barbi C, Ruzzante F, Pedrinolla A, Martignon C, Tarperi C, Schena F, Venturelli M (2021). Electrically induced quadriceps fatigue in the contralateral leg impairs ipsilateral knee extensors performance. Am J Physiol Regul Integr Comp Physiol, 320(5), R747-R756.
  12. Venturelli M, Amann M, Trinity JD, Ives SJ, Richardson RS (2020). Spinal cord injury and vascular function: evidence from diameter-matched vessels. J Appl Physiol (1985), 130(3), 562-570.
  13. Hureau TJ, Weavil JC, Sidhu SK, Thurston TS, Reese VR, Zhao J, Nelson AD, Birgenheier NM, Richardson RS, Amann M (2020). Ascorbate attenuates cycling exercise-induced neuromuscular fatigue but fails to improve exertional dyspnea and exercise tolerance in COPD. J Appl Physiol (1985), 130(1), 69-79.
  14. Weavil JC, Thurston TS, Hureau TJ, Gifford JR, Kithas PA, Broxterman RM, Bledsoe AD, Nativi JN, Richardson RS, Amann M (2020). Heart failure with preserved ejection fraction diminishes peripheral hemodynamics and accelerates exercise-induced neuromuscular fatigue. Am J Physiol Heart Circ Physiol, 320(1), H338-H351.
  15. Amann M, Wan HY, Thurston TS, Georgescu VP, Weavil JC (2021). On the Influence of Group III/IV Muscle Afferent Feedback on Endurance Exercise Performance. [Review]. Exerc Sport Sci Rev, 48(4), 209-216.
  16. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Bledsoe AD, Jessop JE, Buys MJ, Richardson RS, Amann M (2020). The muscle reflex and chemoreflex interaction: ventilatory implications for the exercising human. J Appl Physiol (1985), 129(4), 691-700.
  17. Wan HY, Weavil JC, Thurston TS, Georgescu VP, Hureau TJ, Bledsoe AD, Buys MJ, Jessop JE, Richardson RS, Amann M (2020). The exercise pressor reflex and chemoreflex interaction: cardiovascular implications for the exercising human. J Physiol, 598(12), 2311-2321.
  18. Sidhu SK, Weavil JC, Rossman MJ, Jessop JE, Bledsoe AD, Buys MJ, Supiano MS, Richardson RS, Amann M (2019). Exercise Pressor Reflex Contributes to the Cardiovascular Abnormalities Characterizing: Hypertensive Humans During Exercise. Hypertension, 74(6), 1468-1475.
  19. Hureau TJ, Weavil JC, Thurston TS, Wan HY, Gifford JR, Jessop JE, Buys MJ, Richardson RS, Amann M (2019). Pharmacological attenuation of group III/IV muscle afferents improves endurance performance when oxygen delivery to locomotor muscles is preserved. J Appl Physiol (1985), 127(5), 1257-1266.
  20. Laginestra FG, Amann M, Kirmizi E, Giuriato G, Ruzzante F, Tarperi C, Venturelli M (2019). Electrical stimulation-induced fatigue in the contralateral leg impairs endurance exercise performance [Abstract].
  21. Weavil JC, Amann M (2019). Neuromuscular fatigue during whole body exercise. Curr Opin Physiol, 10, 128-136.
  22. Weavil JC, Amann M (2019). Neuromuscular fatigue during whole body exercise. [Review]. Curr Opin Physiol, 10, 1208-136.
  23. Amann M, Richardson RS, Venturelli M (2019). Reply to Drouin and Tschakovsky. [Letter to the editor]. J Appl Physiol (1985), 126(3), 797.
  24. Layec G, Blain GM, Rossman MJ, Park SY, Hart CR, Trinity JD, Gifford JR, Sidhu SK, Weavil JC, Hureau TJ, Amann M, Richardson RS (2018). Acute High-Intensity Exercise Impairs Skeletal Muscle Respiratory Capacity. Med Sci Sports Exerc, 50(12), 2409-2417.
  25. Sidhu SK, Weavil JC, Thurston TS, Rosenberger D, Jessop JE, Wang E, Richardson RS, McNeil CJ, Amann M (2018). Fatigue-related group III/IV muscle afferent feedback facilitates intracortical inhibition during locomotor exercise. J Physiol, 596(19), 4789-4801.
  26. Berg OK, Kwon OS, Hureau TJ, Clifton HL, Thurston T, Le Fur Y, Jeong EK, Amann M, Richardson RS, Trinity JD, Wang E, Layec G (2018). Maximal strength training increases muscle force generating capacity and the anaerobic ATP synthesis flux without altering the cost of contraction in elderly. Exp Gerontol, 111, 154-161.
  27. Weavil JC, Hureau TJ, Thurston TS, Sidhu SK, Garten RS, Nelson AD, McNeil CJ, Richardson RS, Amann M (2018). Impact of age on the development of fatigue during large and small muscle mass exercise. Am J Physiol Regul Integr Comp Physiol, 315(4), R741-R750.
  28. Broxterman RM, Layec G, Hureau TJ, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson RS (2018). Response. [Letter to the editor]. Med Sci Sports Exerc, 50(8), 1719.
  29. Broxterman RM, Hureau TJ, Layec G, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson RS (2018). Influence of group III/IV muscle afferents on small muscle mass exercise performance: a bioenergetics perspective. J Physiol, 596(12), 2301-2314.
  30. Ansdell P, Thomas K, Howatson G, Amann M, Goodall S (2018). Deception Improves Time Trial Performance in Well-trained Cyclists without Augmented Fatigue. Med Sci Sports Exerc, 50(4), 809-816.
  31. Andrade DC, Arce-Alvarez A, Toledo C, Daz HS, Lucero C, Quintanilla RA, Schultz HD, Marcus NJ, Amann M, Del Rio R (2018). Revisiting the physiological effects of exercise training on autonomic regulation and chemoreflex control in heart failure: does ejection fraction matter? Am J Physiol Heart Circ Physiol, 314(3), H464-H474.
  32. Hureau TJ, Romer LM, Amann M (2016). The 'sensory tolerance limit': A hypothetical construct determining exercise performance? Eur J Sport Sci, 18(1), 13-24.
  33. Broxterman RM, Layec G, Hureau TJ, Morgan DE, Bledsoe AD, Jessop JE, Amann M, Richardson RS (2017). Bioenergetics and ATP Synthesis during Exercise: Role of Group III/IV Muscle Afferents. Med Sci Sports Exerc, 49(12), 2404-2413.
  34. Andrade DC, Arce-Alvarez A, Toledo C, Diaz HS, Lucero C, Quintanilla R, Schultz HD, Marcus NJ, Amann M, and Del Rio R (2017). Revisiting the physiological effects of exercise training on autonomicregulation and chemoreflex control in heart failure: does ejection fraction matter? [Review]. Am J Physiol Heart Circ Physiol, Ahead of print.
  35. Broxterman RM, Layec G, Hureau TJ, Amann M, Richardson RS (2017). Skeletal muscle bioenergetics during all-out exercise: mechanistic insight into the oxygen uptake slow component and neuromuscular fatigue. J Appl Physiol (1985), 122(5), 1208-1217.
  36. Wray DW, Amann M, Richardson RS (2017). Peripheral vascular function, oxygen delivery and utilization: the impact of oxidative stress in aging and heart failure with reduced ejection fraction. [Review]. Heart Fail Rev, 22(2), 149-166.
  37. Taylor JL, Amann M, Duchateau J, Meeusen R, Rice CL (2016). Neural Contributions to Muscle Fatigue: From the Brain to the Muscle and Back Again. [Review]. Med Sci Sports Exerc, 48(11), 2294-2306.
  38. Weavil JC, Sidhu SK, Mangum TS, Richardson RS, Amann M (2016). Fatigue diminishes motoneuronal excitability during cycling exercise. J Neurophysiol, 116(4), 1743-1751.
  39. Blain GM, Mangum TS, Sidhu SK, Weavil JC, Hureau TJ, Jessop JE, Bledsoe AD, Richardson RS, Amann M (2016). Group III/IV muscle afferents limit the intramuscular metabolic perturbation during whole body exercise in humans. J Physiol, 594(18), 5303-15.
  40. Hoeppli M, Thurston T, Sidhu S, Mangum T, Weavil J, Hureau T, Tang W, Hughen R, Light A, Amann M, Schweinhardt P (2016). (352) Differences in psychophysical responses to muscle stimulation in young and old healthy adults. J Pain, 17(4S), S63.
  41. Hoeppli ME, Thurston TS, Sidhu SK, Mangum TS, Weavil JC, Hureau TJ, Tang W, Hughen RW, Light AR, Amann M, Schweinhardt P (2016). Differences in psychophysical responses to muscle stimulation in young and old healthy adults. J Pain, 17(4 Suppl), S63.
  42. Ives SJ, Amann M, Venturelli M, Witman MA, Groot HJ, Wray DW, Morgan DE, Stehlik J, Richardson RS (2016). The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure. Med Sci Sports Exerc, 48(3), 368-76.
  43. Broxterman RM, Richardson RS, Amann M (2015). Less peripheral fatigue after prior exercise is not evidence against the regulation of the critical peripheral fatigue threshold. [Letter to the editor]. J Appl Physiol (1985), 119(12), 1520.
  44. Sidhu SK, Weavil JC, Venturelli M, Rossman MJ, Gmelch BS, Bledsoe AD, Richardson RS, Amann M (2015). Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. Am J Physiol Heart Circ Physiol, 309(9), H1479-89.
  45. Rossman MJ, Trinity JD, Garten RS, Ives SJ, Conklin JD, Barrett-OKeefe Z, Witman MA, Bledsoe AD, Morgan DE, Runnels S, Reese VR, Zhao J, Amann M, Wray DW, Richardson RS (2015). Oral antioxidants improve leg blood flow during exercise in patients with chronic obstructive pulmonary disease. Am J Physiol Heart Circ Physiol, 309(5), H977-85.
  46. Amann M, Light AR (2015). From Petri dish to human: new insights into the mechanisms mediating muscle pain and fatigue, with implications for health and disease. [Review]. Exp Physiol, 100(9), 989-90.
  47. Weavil JC, Sidhu SK, Mangum TS, Richardson RS, Amann M (2015). Intensity-dependent alterations in the excitability of cortical and spinal projections to the knee extensors during isometric and locomotor exercise. Am J Physiol Regul Integr Comp Physiol, 308(12), R998-1007.
  48. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli M (2014). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. [Review]. Auton Neurosci, 188, 19-23.
  49. Sidhu SK, Weavil JC, Venturelli M, Garten RS, Rossman MJ, Richardson RS, Gmelch BS, Morgan DE, Amann M (2014). Spinal mu-opioid receptor-sensitive lower limb muscle afferents determine corticospinal responsiveness and promote central fatigue in upper limb muscle. J Physiol, 592(22), 5011-24.
  50. Hochholzer W, Valina CM, Stratz C, Amann M, Schlittenhardt D, Bttner HJ, Trenk D, Neumann FJ (2014). High-sensitivity cardiac troponin for risk prediction in patients with and without coronary heart disease. Int J Cardiol, 176(2), 444-9.
  51. Amann M, Sidhu SK, Weavil JC, Mangum TS, Venturelli M (2015). Autonomic responses to exercise: group III/IV muscle afferents and fatigue. [Review]. Auton Neurosci, 188, 19-23.
  52. Amann M, Venturelli M, Ives SJ, Morgan DE, Gmelch B, Witman MA, Jonathan Groot H, Walter Wray D, Stehlik J, Richardson RS (2014). Group III/IV muscle afferents impair limb blood in patients with chronic heart failure. Int J Cardiol, 174(2), 368-75.
  53. Rossman MJ, Garten RS, Venturelli M, Amann M, Richardson RS (2014). The role of active muscle mass in determining the magnitude of peripheral fatigue during dynamic exercise. Am J Physiol Regul Integr Comp Physiol, 306(12), R934-40.
  54. Weavil JC, Sidhu SK, Mangum TS, Rossman MJ, Garten RS, Richardson RS, Amann M (2014). Influence of peripheral fatigue and descending drive on the responsiveness of the corticospinal pathway during cycling exercise [Abstract]. Med Sci Sports Exerc.
  55. Venturelli M, Amann M, Layec G, Trinity JD, Ives SJ, Yonnet G, Richardson RS (2014). Flow mediated vasodilation and limb disuse following a spinal cord injury: An assessment unbiased by vessel diameter [Abstract]. Med Sci Sports Exerc.
  56. Rossman MJ, Garten RS, Venturelli M, Amann M, Richardson RS (2014). The role of active muscle mass in determining the magnitude of peripheral fatigue during dynamic exercise [Abstract]. Med Sci Sports Exerc.
  57. Rossman MJ, Garten R, Groot HJ, Reese V, Zhao J, Amann M, Richardson RS (2014). Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol, 305, R1163-1170.
  58. Goodall S, Twomey R, Amann M, Ross EZ, Lovering AT, Romer LM, Subudhi AW, Roach RC (2014). AltitudeOmics: exercise-induced supraspinal fatigue is attenuated in healthy humans after acclimatization to high altitude. Acta Physiol (Oxf), 210(4), 875-88.
  59. Dempsey JA, Blain GM, Amann M (2013). Are type III-IV muscle afferents required for a normal steady-state exercise hyperpnoea in humans? J Physiol, 592(3), 463-74.
  60. Pollak KA, Swenson JD, Vanhaitsma TA, Hughen RW, Jo D, White AT, Light KC, Schweinhardt P, Amann M, Light AR (2013). Exogenously applied muscle metabolites synergistically evoke sensations of muscle fatigue and pain in human subjects. Exp Physiol, 99(2), 368-80.
  61. Girard O, Amann M, Aughey R, Billaut F, Bishop DJ, Bourdon P, Buchheit M, Chapman R, DHooghe M, Garvican-Lewis LA, Gore CJ, Millet GP, Roach GD, Sargent C, Saunders PU, Schmidt W, Schumacher YO (2013). Position statement--altitude training for improving team-sport players' performance: current knowledge and unresolved issues. Br J Sports Med, 47 Suppl 1, i8-16.
  62. Rossman MJ, Garten RS, Groot HJ, Reese V, Zhao J, Amann M, Richardson RS (2013). Ascorbate infusion increases skeletal muscle fatigue resistance in patients with chronic obstructive pulmonary disease. Am J Physiol Regul Integr Comp Physiol, 305(10), R1163-70.
  63. Sidhu SK, Weavil JC, Venturelli M, Richardson RS, Rossman MJ, Garten RS, Amann M (2013). Cortical voluntary activation and responsiveness of corticospinal tract to a remote muscle during cycling exercise sustained to task failure [Abstract]. Society for Neuroscience, book of abstracts, 13, 468.12.
  64. Rossman MJ, Groot HJ, Amann M, Richardson RS (2013). Oxidative stress and COPD: the impact of oral antioxidants on endurance capacity and skeletal muscle fatigue. Med Sci Sports Exerc, 45, 1235-1243.
  65. Amann M, Goodall S, Twomey R, Subudhi AW, Lovering AT, Roach RC (2013). AltitudeOmics: on the consequences of high-altitude acclimatization for the development of fatigue during locomotor exercise in humans. J Appl Physiol (1985), 115(5), 634-42.
  66. Amann M, Venturelli M, Ives SJ, McDaniel J, Layec G, Rossman MJ, Richardson RS (2013). Peripheral fatigue limits endurance exercise via a sensory feedback-mediated reduction in spinal motoneuronal output. J Appl Physiol (1985), 115(3), 355-64.
  67. Rossman MJ, Groot HJ, Reese V, Zhao J, Amann M, Richardson RS (2013). Oxidative stress and COPD: the effect of oral antioxidants on skeletal muscle fatigue. Med Sci Sports Exerc, 45(7), 1235-43.
  68. Dempsey JA, Amann M, Harms CA, Wetter TJ (2012). Respiratory system limitations to performance in the healthy athlete: some answers , more questions! [Review]. 63(6), 157-162.
  69. Rossman MJ, Venturelli M, McDaniel J, Amann M, Richardson RS (2012). Muscle mass and peripheral fatigue: a potential role for afferent feedback? Acta Physiol (Oxf), 206(4), 242-50.
  70. Katayama K, Amann M (2012). Respiratory muscle fatigue modulates the circulatory response to exercise. [Review]. 1, 523-530.
  71. Amann M (2012). Significance of Group III and IV muscle afferents for the endurance exercising human. Clin Exp Pharmacol Physiol, 39(9), 831-5.
  72. Elmer SJ, Marshall CS, Wehmanen K, Amann M, McDaniel J, Martin DT, Martin JC (2012). Effects of locomotor muscle fatigue on joint-specific power production during cycling. Med Sci Sports Exerc, 44(8), 1504-11.
  73. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2011). Implications of group III and IV muscle afferents for high intensity endurance exercise in humans. J Physiol, 589, 5299-5309.
  74. Amann M (2012). Significance of group III and IV muscle afferents for the endurance exercising human. [Review]. Australian Physiological Society. Proceedings, 43, 1-7.
  75. Amann M (2008). Limitation to exercise performance at altitude - where is peripheral muscle fatigue important? 68, 28-30.
  76. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2011). Implications of group III and IV muscle afferents for high intensity endurance exercise performance in humans. J Physiol, 589, 5299-5309.
  77. Amann M, Dempsey JA (2011). Group III and IV muscle afferents contribute to the ventilatory response to exercise. J Appl Physiol (1985), 110, 863-900.
  78. Amann M, Dempsey JA (2011). Quantifying ventilatory effects of afferent blockade - response to letter to editor [Letter to the editor]. J Appl Physiol (1985), 110, 861.
  79. Amann M (2008). Somatosensory feedback from locomotor muscles is a significant determinant of central neural drive during exercise - response to a letter to editor [Letter to the editor]. J Appl Physiol (1985), 105, 105.
  80. Amann M (2012). Pulmonary system limitations to endurance exercise performance in humans. [Review]. Exp Physiol, 97(3), 311-8.
  81. Amann M (2011). Central and peripheral fatigue: interaction during cycling exercise in humans. [Review]. Med Sci Sports Exerc, 43, 2039-2045.
  82. Amann M (2011). Central and peripheral fatigue: interaction during cycling exercise in humans. Med Sci Sports Exerc, 43(11), 2039-45.
  83. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2011). Implications of group III and IV muscle afferents for high-intensity endurance exercise performance in humans. J Physiol, 589(Pt 21), 5299-309.
  84. Ives SJ, Andtbacka RH, Noyes RD, McDaniel J, Amann M, Witman MA, Symons JD, Wray DW, Richardson RS (2011). Human skeletal muscle feed arteries studied in vitro: the effect of temperature on alpha(1)-adrenergic responsiveness. Exp Physiol, 96(9), 907-18.
  85. Amann M, Runnels S, Morgan DE, Trinity JD, Fjeldstad AS, Wray DW, Reese VR, Richardson RS (2011). On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans. J Physiol, 589(Pt 15), 3855-66.
  86. Kolata G, Amann M (2011). One runner's suffering is another's inspiration. The New York Times.
  87. Lovering AT, Stickland MK, Amann M, OBrien MJ, Hokanson JS, Eldridge MW (2011). Effect of a patent foramen ovale on pulmonary gas exchange efficiency at rest and during exercise. J Appl Physiol (1985), 110(5), 1354-61.
  88. Trinity JD, McDaniel J, Venturelli M, Fjeldstad AS, Ives SJ, Witman MA, Barrett-OKeefe Z, Amann M, Wray DW, Richardson RS (2011). Impact of body position on central and peripheral hemodynamic contributions to movement-induced hyperemia: implications for rehabilitative medicine. Am J Physiol Heart Circ Physiol, 300(5), H1885-91.
  89. Hilty L, Lutz K, Maurer K, Rodenkirch T, Spengler CM, Boutellier U, Jancke L, Amann M (2011). Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans. Exp Physiol, 96(5), 505-17.
  90. Amann M, Dempsey JA (2011). Reply to marcora. J Appl Physiol (110(5), p. 1500). United States.
  91. Trinity JD, Amann M, McDaniel J, Fjeldstad A, Barret-OKeefe Z, Runnels S, Morgan DN, Wray DW, Richardson RS (2010). Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. Am J Physiol Heart Circ Physiol, 299, H1693-H1700.
  92. Amann M, Blain G, Proctor L, Sebranek JJ, Pegelow DF, Dempsey JA (2010). Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. J Appl Physiol (1985), 109, 966-976.
  93. Trinity JD, Amann M, McDaniel J, Fjeldstad AS, Barrett-OKeefe Z, Runnels S, Morgan DE, Wray DW, Richardson RS (2010). Limb movement-induced hyperemia has a central hemodynamic component: evidence from a neural blockade study. Am J Physiol Heart Circ Physiol, 299(5), H1693-700.
  94. Amann M, Blain GM, Proctor LT, Sebranek JJ, Pegelow DF, Dempsey JA (2010). Group III and IV muscle afferents contribute to ventilatory and cardiovascular response to rhythmic exercise in humans. J Appl Physiol (1985), 109(4), 966-76.
  95. Francis JT Jr, Quinn TJ, Amann M, LaRoche DP (2010). Defining intensity domains from the end power of a 3-min all-out cycling test. Med Sci Sports Exerc, 42(9), 1769-75.
  96. Amann M, Regan MS, Kobitary M, Eldridge MW, Boutellier U, Pegelow DF, Dempsey JA (2010). Impact of pulmonary system limitations on locomotor muscle fatigue in patients with COPD. Am J Physiol Regul Integr Comp Physiol, 299(1), R314-24.
  97. Amann M, Kayser B (2009). Nervous system function during exercise in hypoxia. [Review]. High Alt Med Biol, 10(2), 149-64.
  98. Amann M, Proctor LT, Sebranek JJ, Eldridge MW, Pegelow DF, Dempsey JA (2008). Somatosensory feedback from the limbs exerts inhibitory influences on central neural drive during whole body endurance exercise. J Appl Physiol (1985), 105(6), 1714-24.
  99. Lovering AT, Stickland MK, Amann M, Murphy JC, OBrien MJ, Hokanson JS, Eldridge MW (2008). Hyperoxia prevents exercise-induced intrapulmonary arteriovenous shunt in healthy humans. J Physiol, 586(18), 4559-65.
  100. Amann M (2008). Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. [Letter to the editor]. J Appl Physiol (1985), 104(5), 1543.
  101. Lossnitzer D, Amann M, Zugck C, Katus H, Brtsch P, Weiss C (2008). Exercise-induced hemostatic activation in patients with dilated cardiomyopathy in sinus rhythm. Blood Coagul Fibrinolysis, 19(2), 146-52.
  102. Amann M, Pegelow DF, Jacques AJ, Dempsey JA (2007). Inspiratory muscle work in acute hypoxia influences locomotor muscle fatigue and exercise performance of healthy humans. Am J Physiol Regul Integr Comp Physiol, 293(5), R2036-45.
  103. Amann M, Romer L, Dempsey J (2007). To the Editor - Response to Noakes' Letter to the Editor. J Physiol.
  104. Amann M, Romer LM, Subudhi AW, Pegelow DF, Dempsey JA (2007). Severity of arterial hypoxaemia affects the relative contributions of peripheral muscle fatigue to exercise performance in healthy humans. J Physiol, 581(Pt 1), 389-403.
  105. Amann M, Eldridge MW, Lovering AT, Stickland MK, Pegelow DF, Dempsey JA (2006). Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humans. J Physiol, 575(Pt 3), 937-52.
  106. Amann M, Romer LM, Pegelow DF, Jacques AJ, Hess CJ, Dempsey JA (2006). Effects of arterial oxygen content on peripheral locomotor muscle fatigue. J Appl Physiol (1985), 101(1), 119-27.
  107. Seifert JG, Kipp RW, Amann M, Gazal O (2005). Muscle damage, fluid ingestion, and energy supplementation during recreational alpine skiing. Int J Sport Nutr Exerc Metab, 15(5), 528-36.
  108. Amann M, Subudhi AW, Walker J, Eisenman P, Shultz B, Foster C (2004). An evaluation of the predictive validity and reliability of ventilatory threshold. Med Sci Sports Exerc, 36(10), 1716-22.
  109. Amann M, Subudhi A, Foster C (2004). Influence of testing protocol on ventilatory thresholds and cycling performance. Med Sci Sports Exerc, 36(4), 613-22.

Global Impact

Education History

Type School Degree
Graduate Training Technical University of Munich
Exercise Physiology		 M.S.