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Elliot H. Smith, PhD

Languages spoken: English, French, Indonesian

Academic Information

Departments: Neurosurgery - Assistant Professor

Academic Office Information

Education History

Fellowship Columbia University
Postdoctoral Training
Doctoral Training University of Utah
Neural Engineering
Undergraduate University of Washington
Psychology; Minor: Mathematics

Selected Publications

  1. Edward M Merricks, Elliot H Smith, Ronald G Emerson, Lisa M Bateman, Guy M McKhann, Robert R Goodman, Sameer A Sheth, Bradley Greger, Paul A House, Andrew J Trevelyan, Catherine A Schevon (2021). Neuronal firing and waveform alterations through ictal recruitment in humans. J Neurosci.
  2. Catherine A Schevon Elliot H Smith, Edward M Merricks, Jyun-You Liou, Camilla Casadei, Lucia Melloni, Thomas Thesen, Daniel J Friedman, Werner K Doyle, Ronald G Emerson, Robert R Goodman, Guy M McKhann II, Sameer A Sheth, John D Rolston (2020). Dual mechanisms of ictal high frequency oscillations in human rhythmic onset seizures. Sci Rep.
  3. Bornali Kundu, Tyler S Davis, Brian Philip, Elliot H Smith, Amir Arain, Angela Peters, Blake Newman, Christopher R Butson, John D Rolston (2020). A systematic exploration of parameters affecting evoked intracranial potentials in patients with epilepsy. Brain Stimul.
  4. Rose M Caston, Elliot H Smith, Tyler S Davis, John D Rolston (2020). The cerebral localization of pain: anatomical and functional considerations for targeted electrical therapies. [Review]. J Clin Med.
  5. Abhinav Goyal, Jonathan Miller, Salman E Qasim, Andrew J Watrous, Honghui Zhang, Joel M Stein, Cory S Inman, Robert E Gross, Jon T Willie, Bradley Lega, Jui-Jui Lin, Ashwini Sharan, Chengyuan Wu, Michael R Sperling, Sameer A Sheth, Guy M McKhann, Elliot H Smith, Catherine Schevon, Joshua Jacobs (2020). Functionally distinct high and low theta oscillations in the human hippocampus. Nat Commun.
  6. Jyun-you Liou, Elliot H Smith, Lisa M Bateman, Samuel L Bruce, Guy M McKhann, Robert R Goodman, Ronald G Emerson, Catherine A Schevon, LF Abbott (2020). A model for focal seizure onset, propagation, evolution, and progression. Elife.
  7. Melina Tsitsiklis, Jonathan Miller, Salman E Qasim, Cory S Inman, Robert E Gross, Jon T Willie, Elliot H Smith, Sameer A Sheth, Catherine A Schevon, Michael R Sperling, Ashwini Sharan, Joel M Stein, Joshua Jacobs (2020). Single-neuron representations of spatial targets in humans. Curr Biol.
  8. James OSullivan, Jose Herrero, Elliot Smith, Catherine Schevon, Guy M McKhann, Sameer A Sheth, Ashesh D Mehta, Nima Mesgarani (2019). Hierarchical encoding of attended auditory objects in multi-talker speech perception. Neuron.
  9. Salman E Qasim, Jonathan Miller, Cory S Inman, Robert E Gross, Jon T Willie, Bradley Lega, Jui-Jui Lin, Ashwini Sharan, Chengyuan Wu, Michael R Sperling, Sameer A Sheth, Guy M McKhann, Elliot H Smith, Catherine Schevon, Joel M Stein, Joshua Jaco (2019). Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex. Nat Neurosci.
  10. Hannah E Goldstein, Elliot H Smith, Robert E Gross, Barbara C Jobst, Bradley C Lega, Michael R Sperling, Gregory A Worrell, Kareem A Zaghloul, Paul A Wanda, Michael J Kahana, Daniel S Rizzuto, Catherine A Schevon, Guy M McKhann, Sameer A Sheth (2019). Risk of seizures induced by intracranial research stimulation: analysis of 770 stimulation sessions. J Neural Eng.
  11. Elliot H Smith, Guillermo Horga, Mark J Yates, Charles B Mikell, Garrett P Banks, Yagna J Pathak, Catherine A Schevon, Guy M McKhann, Benjamin Y Hayden, Matthew M Botvinick, Sameer A Sheth (2019). Widespread temporal coding of cognitive control in the human prefrontal cortex. Nat Neurosci.
  12. Michael Wenzel, Shuting Han, Elliot Smith, Hoel Erik, Bradley Greger, Paul House, Rafael Yuste (2019). Reduced repertoire of cortical microstates and neuronal ensembles in medically-induced loss of consciousness. Cell Syst.
  13. Liou JY, Ma H, Wenzel M, Zhao M, Baird-Daniel E, Smith EH, Daniel A, Emerson R, Yuste R, Schwartz TH, Schevon CA (2018). Role of inhibitory control in modulating focal seizure spread. Brain, 141(7), 2083-2097.
  14. Miller J, Watrous AJ, Tsitsiklis M, Lee SA, Sheth SA, Schevon CA, Smith EH, Sperling MR, Sharan A, Asadi-Pooya AA, Worrell GA, Meisenhelter S, Inman CS, Davis KA, Lega B, Wanda PA, Das SR, Stein JM, Gorniak R, Jacobs J (2018). Lateralized hippocampal oscillations underlie distinct aspects of human spatial memory and navigation. Nat Commun, 9(1), 2423.
  15. Liou JY, Smith EH, Bateman LM, McKhann GM, Goodman RR, Greger B, Davis TS, Kellis SS, House PA, Schevon CA (2017). Multivariate regression methods for estimating velocity of ictal discharges from human microelectrode recordings. J Neural Eng, 14(4), 044001.
  16. Sklar S, Walmer M, Sacre P, Schevon CA, Srinivasan S, Banks GP, Yates MJ, McKhann GM, Sheth SA, Sarma SV, Smith EH (2017). Neuronal activity in human anterior cingulate cortex modulates with internal cognitive state during multi-source interference task. Conf Proc IEEE Eng Med Biol Soc, 2017, 962-65.
  17. Sheth S, Horga G, Yates M, Pathak Y, Schevon C, McKhann G, Smith E (2017). Neuronal mechanisms of cognitive control in human prefrontal cortex [Abstract]. Neurosurgery.
  18. Smith EH, Schevon CA (2016). Toward a Mechanistic Understanding of Epileptic Networks. [Review]. Curr Neurol Neurosci Rep, 16(11), 97.
  19. Dyster TG, Pathak Y, Smith E, Sheth SA (2016). An easily implemented, open access, semi-automated pipeline for intracranial electrode localization [Abstract]. Neurosurgery, 63(CN_suppl_1), 156.
  20. Smith EH, Liou JY, Davis TS, Merricks EM, Kellis SS, Weiss SA, Greger B, House PA, McKhann GM 2nd, Goodman RR, Emerson RG, Bateman LM, Trevelyan AJ, Schevon CA (2016). The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures. Nat Commun, 7, 11098.
  21. Eissa TL, Tryba AK, Marcuccilli CJ, Ben-Mabrouk F, Smith EH, Lew SM, Goodman RR, McKhann GM Jr, Frim DM, Pesce LL, Kohrman MH, Emerson RG, Schevon CA, van Drongelen W (2016). Multiscale Aspects of Generation of High-Gamma Activity during Seizures in Human Neocortex.LID - 10.1523/ENEURO.0141-15.2016 [doi]LID - ENEURO.0141-15.2016 [pii]. eNeuro, 3(2).
  22. Smith EH, Banks GP, Mikell CB, Cash SS, Patel SR, Eskandar EN, Sheth SA (2015). Frequency-Dependent Representation of Reinforcement-Related Information in the Human Medial and Lateral Prefrontal Cortex. J Neurosci, 35(48), 15827-36.
  23. Merricks EM, Smith EH, McKhann GM, Goodman RR, Bateman LM, Emerson RG, Schevon CA, Trevelyan AJ (2015). Single unit action potentials in humans and the effect of seizure activity. Brain, 138(Pt 10), 2891-906.
  24. McGovern RA, Ratneswaren T, Smith EH, Russo JF, Jongeling AC, Bateman LM, Schevon CA, Feldstein NA, McKhann GM 2nd, Sheth S (2015). Investigating the function of deep cortical and subcortical structures using stereotactic electroencephalography: lessons from the anterior cingulate cortex.LID - 10.3791/52773 [doi]. J Vis Exp, (98).
  25. Mikell C, Smith E, Brown L, McKhann G, Sheth S (2014). Spatial Conflict is Encoded in Human MT+ [Abstract]. Neurosurgery.
  26. Smith E, Kellis S, House P, Greger B (2013). Decoding stimulus identity from multi-unit activity and local field potentials along the ventral auditory stream in the awake primate: implications for cortical neural prostheses. J Neural Eng, 10(1), 016010.
  27. Smith E, Duede S, Hanrahan S, Davis T, House P, Greger B (2013). Seeing is believing: neural representations of visual stimuli in human auditory cortex correlate with illusory auditory perceptions. PLoS One, 8(9), e73148.
  28. Smith EH, Kellis SS, House PA, Greger B (2012). Information transfer along the ventral auditory processing stream in the awake macaque. 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, San Diego, CA, 5178-81.
  29. Smith EH (2011). Temporal processing in the auditory core: transformation or segregation? [Review]. J Neurophysiol, 106(6), 2791-3.