Richard Holubkov

Richard Holubkov, PhD

Languages spoken: Czech, German, English

Academic Information

Departments Primary - Pediatrics , Adjunct - Family & Preventive Medicine , Adjunct - Population Health Sciences

Divisions: Critical Care , Public Health

Academic Office Information

rholubkov@hrc.utah.edu

Dr. Holubkov has over 25 years of experience as an applied biostatistician, focusing on the design, execution and analysis of prospective interventional studies, with a focus on pediatrics and cardiology. Dr. Holubkov received his Ph.D. in Biostatistics from the University of Washington in 1995, and was a faculty member at the University of Pittsburgh prior to joining the University of Utah in 2002. At the University of Pittsburgh, Dr. Holubkov was chief biostatistician for the NHLBI Registries of Percutaneous Coronary Interventions and the two NHLBI Bypass Angioplasty Revascularization Investigations (BARI), and he also directed the Coordinating Center for an industry-sponsored international randomized trial comparing two mechanical heart valves.



At the University of Utah, he is the Co-Principal Investigator and Chief Biostatistician for the NICHD Collaborative Pediatric Critical Care Research Network (CPCCRN) Coordinating Center since the network'e (CPCCRN) inception, Director of the Coordinating Center for the NHLBI-funded Hydrocephalus Research Network (HCRN), Co-Director of the Study Design and Biostatistics Center in the Center for Clinical Sciences (CCTS), and the chief biostatistician for the NHLBI’s Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) trials.

Dr. Holubkov also regularly teaches courses on the design and analysis of randomized clinical trials and mentors clinical investigators as well as students in the Masters of Statistics Program. Dr. Holubkov has authored or co-authored more than 100 publications in the areas of pediatrics, cardiology and statistical methodology. He serves on several Data Safety Monitoring Boards and protocol review committees.

Education History

Undergraduate University of Chicago
 BS
Graduate Training Carnegie-Mellon University
 MS
Graduate Training University of Washington
 MS
Doctoral Training University of Washington
 PhD

Selected Publications

Journal Article

  1. Sharaf BL, Pepine CJ, Kerensky RA, Reis SE, Reichek N, Rogers WJ, Sopko G, Kelsey SF, Holubkov R, Olson M, Miele NJ, Williams DO, Merz CN, WISE Study Group (2001). Detailed angiographic analysis of women with suspected ischemic chest pain (pilot phase data from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation [WISE] Study Angiographic Core Laboratory). The American journal of cardiology, 87(8), 937-41; A3. (Read full article)
  2. Strahle JM, Mahaney KB, Morales DM, Buddhala C, Shannon CN, Wellons JC 3rd, Kulkarni AV, Jensen H, Reeder RW, Holubkov R, Riva-Cambrin JK, Whitehead WE, Rozzelle CJ, Tamber M, Pollack IF, Naftel RP, Kestle JRW, Limbrick DD Jr, and for the Hydrocephalus Clinical Research Network (2021). Longitudinal CSF Iron Pathway Proteins in Posthemorrhagic Hydrocephalus: Associations with Ventricle Size and Neurodevelopmental Outcomes. Annals of neurology, 90(2), 217-226. (Read full article)
  3. Branch DW, VanBuren JM, Porter TF, Holmgren C, Holubkov R, Page K, Burchard J, Lam GK, Esplin M (2021). Prediction and Prevention of Preterm Birth: A Prospective, Randomized Intervention Trial. American journal of perinatology, 40(10), 1071-1080. (Read full article)
  4. Nunn AC, Jones HE, Morosanu CO, Singleton WGB, Williams MA, Nagel SJ, Luciano MG, Zwimpfer TJ, Holubkov R, Wisoff JH, McKhann GM 2nd, Hamilton MG, Edwards R (2021). Extended lumbar drainage in idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis of diagnostic test accuracy. British journal of neurosurgery, 35(3), 285-291. (Read full article)
  5. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2021). Complicated Grief, Depression and Post-Traumatic Stress Symptoms Among Bereaved Parents following their Child's Death in the Pediatric Intensive Care Unit: A Follow-Up Study. The American journal of hospice & palliative care, 39, 10499091211015913. (Read full article)
  6. Jensen AR, Evans LL, Meert KL, VanBuren JM, Richards R, Alvey JS, Holubkov R, Pollack MM, Burd RS, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Assessment of Health-Related Quality of Life and Functional Outcomes after Pediatric Trauma Project Investigators (2021). Functional status impairment at six-month follow-up is independently associated with child physical abuse mechanism. Child abuse & neglect, 122, 105333. (Read full article)
  7. Pollack MM, Holubkov R, Funai T, Berger JT, Clark AE, Meert K, Berg RA, Carcillo J, Wessel DL, Moler F, Dalton H, Newth CJ, Shanley T, Harrison RE, Doctor A, Jenkins TL, Tamburro R, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2015). Simultaneous Prediction of New Morbidity, Mortality, and Survival Without New Morbidity From Pediatric Intensive Care: A New Paradigm for Outcomes Assessment. Critical care medicine, 43(8), 1699-709. (Read full article)
  8. Sutton RM, Reeder RW, Landis WP, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2019). Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes. Critical care medicine, 47(11), 1627-1636. (Read full article)
  9. Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators (2020). Trajectory of Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Critical care medicine, 48(3), 329-337. (Read full article)
  10. Zimmerman JJ, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Wong H, Chima RS, Holubkov R, Coleman W, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock K, Dean JM, Reeder RW, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators (2020). Critical Illness Factors Associated With Long-Term Mortality and Health-Related Quality of Life Morbidity Following Community-Acquired Pediatric Septic Shock. Critical care medicine, 48(3), 319-328. (Read full article)
  11. Meert KL, Banks R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2020). Morbidity and Mortality in Critically Ill Children. II. A Qualitative Patient-Level Analysis of Pathophysiologies and Potential Therapeutic Solutions. Critical care medicine, 48(6), 799-807. (Read full article)
  12. Morgan RW, Reeder RW, Meert KL, Telford R, Yates AR, Berger JT, Graham K, Landis WP, Kilbaugh TJ, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman D, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Sutton RM, Eunice Kennedy Shriver National Institute of Child Health and Human Development/Collaborative Pediatric Critical Care Research Network (CPCCRN) Pediatric Intensive Care Quality of Cardio-Pulmonary Resuscitation (PICqCPR) Investigators (2020). Survival and Hemodynamics During Pediatric Cardiopulmonary Resuscitation for Bradycardia and Poor Perfusion Versus Pulseless Cardiac Arrest. Critical care medicine, 48(6), 881-889. (Read full article)
  13. Pollack MM, Banks R, Holubkov R, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2020). Morbidity and Mortality in Critically Ill Children. I. Pathophysiologies and Potential Therapeutic Solutions. Critical care medicine, 48(6), 790-798. (Read full article)
  14. Barnard ND, Alwarith J, Rembert E, Brandon L, Nguyen M, Goergen A, Horne T, do Nascimento GF, Lakkadi K, Tura A, Holubkov R, Kahleova (2021). A Mediterranean Diet and Low-Fat Vegan Diet to Improve Body Weight and Cardiometabolic Risk Factors: A Randomized, Cross-over Trial. Journal of the American College of Nutrition, 41, 1-13. (Read full article)
  15. Keenan HT, Clark AE, Holubkov R, Cox CS, Patel RP, Moore KR, Ewing-Cobbs (2020). Latent Class Analysis to Classify Injury Severity in Pediatric Traumatic Brain Injury. Journal of neurotrauma, 37(13), 1512-1520. (Read full article)
  16. Williams MA, Nagel SJ, Luciano MG, Relkin N, Zwimpfer TJ, Katzen H, Holubkov R, Moghekar A, Wisoff JH, McKhann GM, Golomb J, Edwards RJ, Hamilton M (2019). The clinical spectrum of hydrocephalus in adults: report of the first 517 patients of the Adult Hydrocephalus Clinical Research Network registry. Journal of neurosurgery, 132(6), 1773-1784. (Read full article)
  17. Zwimpfer TJ, Salterio N, Williams MA, Holubkov R, Katzen H, Luciano MG, Moghekar A, Nagel SJ, Wisoff JH, Golomb J, McKhann GM, Edwards RJ, Hamilton MG, Adult Hydrocephalus Clinical Research Network (2021). Cognitive and gait outcomes after primary endoscopic third ventriculostomy in adults with chronic obstructive hydrocephalus. Journal of neurosurgery, 136, 1-8. (Read full article)
  18. Isaacs AM, Ball CG, Sader N, Muram S, Ben-Israel D, Urbaneja G, Dronyk J, Holubkov R, Hamilton M (2021). Reducing the risks of proximal and distal shunt failure in adult hydrocephalus: a shunt outcomes quality improvement study. Journal of neurosurgery, 136, 1-10. (Read full article)
  19. Simon TD, Kronman MP, Whitlock KB, Gove N, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Luerssen TG, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons JC 3rd, Whitehead WE, Mayer-Hamblett (2016). Variability in Management of First Cerebrospinal Fluid Shunt Infection: A Prospective Multi-Institutional Observational Cohort Study. The Journal of pediatrics, 179, 185-191.e2. (Read full article)
  20. Flaherty BF, Jackson ML, Cox CS Jr, Clark A, Ewing-Cobbs L, Holubkov R, Moore KR, Patel RP, Keenan H (2020). Ability of the PILOT score to predict 6-month functional outcome in pediatric patients with moderate-severe traumatic brain injury. Journal of pediatric surgery, 55(7), 1238-1244. (Read full article)
  21. Carcillo JA, Dean JM, Holubkov R, Berger J, Meert KL, Anand KJS, Zimmerman JJ, Newth CJL, Harrison R, Burr J, Willson DF, Nicholson C, Bell MJ, Berg RA, Shanley TP, Heidemann SM, Dalton H, Jenkins TL, Doctor A, Webster A, Tamburro R (2017). Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial. JPEN. Journal of parenteral and enteral nutrition, 41(8), 1325-1335. (Read full article)
  22. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC Jr, Dean JM, THAPCA Trial Investigators (2015). Therapeutic hypothermia after out-of-hospital cardiac arrest in children. The New England journal of medicine, 372(20), 1898-908. (Read full article)
  23. Cress M, Kestle JR, Holubkov R, Riva-Cambrin (2013). Risk factors for pediatric arachnoid cyst rupture/hemorrhage: a case-control study. Neurosurgery, 72(5), 716-22; discussion 722. (Read full article)
  24. Topjian AA, Sutton RM, Reeder RW, Telford R, Meert KL, Yates AR, Morgan RW, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Pollack MM, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators., Zuppa AF, Graham K, Twelves C, Diliberto MA, Landis WP, Tomanio E, Kwok J, Bell MJ, Abraham A, Sapru A, Alkhouli MF, Heidemann S, Pawluszka A, Hall MW, Steele L, Shanley TP, Weber M, Dalton HJ, Bell A, Mourani PM, Malone K, Locandro C, Coleman W, Peterson A, Thelen J, Doctor (2019). The association of immediate post cardiac arrest diastolic hypertension and survival following pediatric cardiac arrest. Resuscitation, 141, 88-95. (Read full article)
  25. Topjian AA, Telford R, Holubkov R, Nadkarni VM, Berg RA, Dean JM, Moler FW, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators (2019). The association of early post-resuscitation hypotension with discharge survival following targeted temperature management for pediatric in-hospital cardiac arrest. Resuscitation, 141, 24-34. (Read full article)
  26. Slomine BS, Silverstein FS, Page K, Holubkov R, Christensen JR, Dean JM, Moler FW, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators (2019). Relationships between three and twelve month outcomes in children enrolled in the therapeutic hypothermia after pediatric cardiac arrest trials. Resuscitation, 139, 329-336. (Read full article)
  27. Meert K, Slomine BS, Silverstein FS, Christensen J, Ichord R, Telford R, Holubkov R, Dean JM, Moler FW, Therapeutic Hypothermia after Paediatric Cardiac Arrest (THAPCA) Trial Investigatorss (2019). One-year cognitive and neurologic outcomes in survivors of paediatric extracorporeal cardiopulmonary resuscitation. Resuscitation, 139, 299-307. (Read full article)
  28. Wolfe HA, Sutton RM, Reeder RW, Meert KL, Pollack MM, Yates AR, Berger JT, Newth CJ, Carcillo JA, McQuillen PS, Harrison RE, Moler FW, Carpenter TC, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network., Pediatric Intensive Care Quality of Cardiopulmonary Resuscitation Investigators (2019). Functional outcomes among survivors of pediatric in-hospital cardiac arrest are associated with baseline neurologic and functional status, but not with diastolic blood pressure during CPR. Resuscitation, 143, 57-65. (Read full article)
  29. Landis WP, Morgan RW, Reeder RW, Graham K, Siems A, Diddle JW, Pollack MM, Maa T, Fernandez RP, Yates AR, Tilford B, Ahmed T, Meert KL, Schneiter C, Bishop R, Mourani PM, Naim MY, Friess S, Burns C, Manga A, Franzon D, Tabbutt S, McQuillen PS, Horvat CM, Bochkoris M, Carcillo JA, Huard L, Federman M, Sapru A, Viteri S, Hehir DA, Notterman DA, Holubkov R, Dean JM, Nadkarni VM, Berg RA, Wolfe HA, Sutton RM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Investigators the National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators (2020). Variability in chest compression rate calculations during pediatric cardiopulmonary resuscitation. Resuscitation, 149, 127-133. (Read full article)
  30. Mah KE, Alten JA, Cornell TT, Selewski DT, Askenazi D, Fitzgerald JC, Topjian A, Page K, Holubkov R, Slomine BS, Christensen JR, Dean JM, Moler F (2021). Acute kidney injury after in-hospital cardiac arrest. Resuscitation, 160, 49-58. (Read full article)
  31. Pearson K, Jordan KC, Metos J, Holubkov R, Nanjee MN, Mihalopoulos N (2020). Association of Prepregnancy BMI, Gestational Weight Gain, and Child Birth Weight with Metabolic Dysfunction in Children and Adolescents with Obesity. Southern medical journal, 113(10), 482-487. (Read full article)
  32. Burd RS, Jensen AR, VanBuren JM, Alvey JS, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Functional Outcomes and Health-Related Quality of Life after Pediatric Trauma Investigators (2021). Long-Term Outcomes after Pediatric Injury: Results of the Assessment of Functional Outcomes and Health-Related Quality of Life after Pediatric Trauma Study. Journal of the American College of Surgeons, 233(6), 666-675.e2. (Read full article)
  33. Muszynski JA, Banks R, Reeder RW, Hall MW, Berg RA, Zuppa A, Shanley TP, Cornell TT, Newth CJL, Pollack MM, Wessel D, Doctor A, Lin JC, Harrison RE, Meert KL, Dean JM, Holubkov R, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2021). Outcomes Associated with Early RBC Transfusion in Pediatric Severe Sepsis: A Propensity-Adjusted Multicenter Cohort Study. Shock (Augusta, Ga.), 57(1), 88-94. (Read full article)
  34. Keenan HT, Clark AE, Holubkov R, Ewing-Cobbs (2020). Changing Healthcare and School Needs in the First Year After Traumatic Brain Injury. The Journal of head trauma rehabilitation, 35(1), E67-E77. (Read full article)
  35. Barnard ND, Kahleova H, Holtz DN, Del Aguila F, Neola M, Crosby LM, Holubkov (2021). The Women's Study for the Alleviation of Vasomotor Symptoms (WAVS): a randomized, controlled trial of a plant-based diet and whole soybeans for postmenopausal women. Menopause (New York, N.Y.), 28(10), 1150-1156. (Read full article)
  36. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Notterman DA, Colville G, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2021). Post-Traumatic Growth in Parents following Their Child's Death in a Pediatric Intensive Care Unit. Journal of palliative medicine, 25, 265-273. (Read full article)
  37. Christensen JR, Slomine BS, Silverstein FS, Page K, Holubkov R, Dean JM, Moler FW, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA) Trial Investigators (2019). Cardiac Arrest Outcomes in Children With Preexisting Neurobehavioral Impairment. Pediatric critical care medicine, 20(6), 510-517. (Read full article)
  38. Gildea MR, Moler FW, Page K, Meert K, Holubkov R, Dean JM, Christensen JR, Slomine B (2020). Methods Used to Maximize Follow-Up: Lessons Learned From the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials. Pediatric critical care medicine, 21(1), 4-11. (Read full article)
  39. Carcillo JA, Berg RA, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Banks R, Kellum JA, Holubkov R, Notterman DA, Dean JM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2019). A Multicenter Network Assessment of Three Inflammation Phenotypes in Pediatric Sepsis-Induced Multiple Organ Failure. Pediatric critical care medicine, 20(12), 1137-1146. (Read full article)
  40. Berger JT, Maddux AB, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Yates AR, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2020). Inhaled Nitric Oxide Use in Pediatric Hypoxemic Respiratory Failure. Pediatric critical care medicine, 21(8), 708-719. (Read full article)
  41. Murphy LK, Palermo TM, Meert KL, Reeder R, Dean JM, Banks R, Berg RA, Carcillo JA, Chima R, McGalliard J, Haaland W, Holubkov R, Mourani PM, Pollack MM, Sapru A, Sorenson S, Varni JW, Zimmerman (2020). Longitudinal Trajectories of Caregiver Distress and Family Functioning After Community-Acquired Pediatric Septic Shock. Pediatric critical care medicine, 21(9), 787-796. (Read full article)
  42. Meert KL, Reeder RW, Maddux AB, Banks R, Berg RA, Newth CJ, Hall MW, Quasney M, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, McGalliard J, Dean JM, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators., following is a summary of LAPSE Performance Sites, Principal Investigators (PIs), Coinvestigators (CIs), Research Coordinators (RCs), and Allied Research Personnel (2021). Health-Related Quality of Life After Community-Acquired Septic Shock in Children With Preexisting Severe Developmental Disabilities. Pediatric critical care medicine, 22(5), e302-e313. (Read full article)
  43. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert KL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2021). Therapeutic Alliance Between Bereaved Parents and Physicians in the PICU. Pediatric critical care medicine, 22(4), e243-e252. (Read full article)
  44. Pollack MM, Banks R, Holubkov R, Meert KL, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2021). Long-Term Outcome of PICU Patients Discharged With New, Functional Status Morbidity. Pediatric critical care medicine, 22(1), 27-39. (Read full article)
  45. Meert KL, Reeder R, Maddux AB, Banks R, Berg RA, Zuppa A, Newth CJ, Wessel D, Pollack MM, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Sorenson S, Varni JW, McGalliard J, Haaland W, Whitlock KB, Dean JM, Zimmerman JJ, and the Life After Pediatric Sepsis Evaluation (LAPSE) Investigators (2020). Trajectories and Risk Factors for Altered Physical and Psychosocial Health-Related Quality of Life After Pediatric Community-Acquired Septic Shock. Pediatric critical care medicine, 21(10), 869-878. (Read full article)
  46. Mihalopoulos NL, Yap JT, Beardmore B, Holubkov R, Nanjee MN, Hoffman J (2020). Cold-Activated Brown Adipose Tissue is Associated with Less Cardiometabolic Dysfunction in Young Adults with Obesity. Obesity (Silver Spring, Md.), 28(5), 916-923. (Read full article)
  47. Limbrick DD, Morales DM, Shannon CN, Wellons JC, Kulkarni AV, Alvey JS, Reeder RW, Freimann V, Holubkov R, Riva-Cambrin JK, Whitehead WE, Rozzelle CJ, Tamber M, Oakes WJ, Drake JM, Pollack IF, Naftel RP, Inder TE, Kestle JR, Hydrocephalus Clinical Research Network (2021). Cerebrospinal fluid NCAM-1 concentration is associated with neurodevelopmental outcome in post-hemorrhagic hydrocephalus of prematurity. PloS one, 16(3), e0247749. (Read full article)
  48. Riva-Cambrin J, Kestle JRW, Rozzelle CJ, Naftel RP, Alvey JS, Reeder RW, Holubkov R, Browd SR, Cochrane DD, Limbrick DD, Shannon CN, Simon TD, Tamber MS, Wellons JC, Whitehead WE, Kulkarni AV, Hydrocephalus Clinical Research Network (2019). Predictors of success for combined endoscopic third ventriculostomy and choroid plexus cauterization in a North American setting: a Hydrocephalus Clinical Research Network study. Journal of neurosurgery. Pediatrics, 24(2), 128-138. (Read full article)
  49. Pindrik J, Riva-Cambrin J, Kulkarni AV, Alvey JS, Reeder RW, Pollack IF, Wellons JC, Jackson EM, Rozzelle CJ, Whitehead WE, Limbrick DD, Naftel RP, Shannon C, McDonald PJ, Tamber MS, Hankinson TC, Hauptman JS, Simon TD, Krieger MD, Holubkov R, Kestle JRW, Hydrocephalus Clinical Research Network (2020). Surgical resource utilization after initial treatment of infant hydrocephalus: comparing ETV, early experience of ETV with choroid plexus cauterization, and shunt insertion in the Hydrocephalus Clinical Research Network. Journal of neurosurgery. Pediatrics, 26, 1-9. (Read full article)
  50. Tamber MS, Kestle JRW, Reeder RW, Holubkov R, Alvey J, Browd SR, Drake JM, Kulkarni AV, Limbrick DD, McDonald PJ, Rozzelle CJ, Simon TD, Naftel R, Shannon CN, Wellons JC, Whitehead WE, Riva-Cambrin J, Hydrocephalus Clinical Research Network (2020). Temporal trends in surgical procedures for pediatric hydrocephalus: an analysis of the Hydrocephalus Clinical Research Network Core Data Project. Journal of neurosurgery. Pediatrics, 27, 1-8. (Read full article)
  51. Hauptman JS, Kestle J, Riva-Cambrin J, Kulkarni AV, Browd SR, Rozzelle CJ, Whitehead WE, Naftel RP, Pindrik J, Limbrick DD, Drake J, Wellons JC, Tamber MS, Shannon CN, Simon TD, Pollack IF, McDonald PJ, Krieger MD, Chu J, Hankinson TC, Jackson EM, Alvey JS, Reeder RW, Holubkov R, Hydrocephalus Clinical Research Network (2020). Predictors of fast and ultrafast shunt failure in pediatric hydrocephalus: a Hydrocephalus Clinical Research Network study. Journal of neurosurgery. Pediatrics, 27, 1-10. (Read full article)
  52. Kahleova H, Hlozkova A, Fleeman R, Fletcher K, Holubkov R, Barnard N (2019). Fat Quantity and Quality, as Part of a Low-Fat, Vegan Diet, Are Associated with Changes in Body Composition, Insulin Resistance, and Insulin Secretion. A 16-Week Randomized Controlled Trial. Nutrients, 11(3), (Read full article)
  53. Kahleova H, Rembert E, Alwarith J, Yonas WN, Tura A, Holubkov R, Agnello M, Chutkan R, Barnard N (2020). Effects of a Low-Fat Vegan Diet on Gut Microbiota in Overweight Individuals and Relationships with Body Weight, Body Composition, and Insulin Sensitivity. A Randomized Clinical Trial. Nutrients, 12(10), (Read full article)
  54. Ewing-Cobbs L, Montroy JJ, Clark AE, Holubkov R, Cox CS Jr, Keenan H (2021). As Time Goes by: Understanding Child and Family Factors Shaping Behavioral Outcomes After Traumatic Brain Injury. Frontiers in neurology, 12, 687740. (Read full article)
  55. Hung M, Li W, Hon ES, Su S, Su W, He Y, Sheng X, Holubkov R, Lipsky M (2020). Prediction of 30-Day Hospital Readmissions for All-Cause Dental Conditions using Machine Learning. Risk management and healthcare policy, 13, 2047-2056. (Read full article)
  56. Barnard ND, Rembert E, Freeman A, Bradshaw M, Holubkov R, Kahleova (2021). Blood Type Is Not Associated with Changes in Cardiometabolic Outcomes in Response to a Plant-Based Dietary Intervention. Journal of the Academy of Nutrition and Dietetics, 121(6), 1080-1086. (Read full article)
  57. Siems A, Banks R, Holubkov R, Meert KL, Bauerfeld C, Beyda D, Berg RA, Bulut Y, Burd RS, Carcillo J, Dean JM, Gradidge E, Hall MW, McQuillen PS, Mourani PM, Newth CJL, Notterman DA, Priestley MA, Sapru A, Wessel DL, Yates AR, Zuppa AF, Pollack M (2020). Structured Chart Review: Assessment of a Structured Chart Review Methodology. Hospital pediatrics, 10(1), 61-69. (Read full article)
  58. Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators., Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates A (2021). Factors Associated With Functional Impairment After Pediatric Injury. JAMA surgery, 156(8), e212058. (Read full article)
  59. Gildea MR, Moler FW, Page K, Pemberton VL, Holubkov R, Nadkarni VM, Dean JM, Olson L (2019). Practice Patterns after the Therapeutic Hypothermia After Pediatric Cardiac Arrest Out-of-Hospital Trial: A Survey of Pediatric Critical Care Physicians. Journal of pediatric intensive care, 8(2), 71-77. (Read full article)
  60. Bennett EE, VanBuren J, Holubkov R, Bratton S (2018). Presence of Invasive Devices and Risks of Healthcare-Associated Infections and Sepsis. Journal of pediatric intensive care, 7(4), 188-195. (Read full article)
  61. Pinto NP, Berg RA, Zuppa AF, Newth CJ, Pollack MM, Meert KL, Hall MW, Quasney M, Sapru A, Carcillo JA, McQuillen PS, Mourani PM, Chima RS, Holubkov R, Nadkarni VM, Reeder RW, Zimmerman JJ, Life After Pediatric Sepsis Evaluation (LAPSE) Investigators (2021). Improvement in Health-Related Quality of Life After Community Acquired Pediatric Septic Shock. Frontiers in pediatrics, 9, 675374. (Read full article)
  62. Kahleova H, Rembert E, Nowak A, Holubkov R, Barnard N (2021). Effect of a diet intervention on cardiometabolic outcomes: Does race matter? A randomized clinical trial. Clinical nutrition ESPEN, 41, 126-128. (Read full article)
  63. Kahleova H, McCann J, Alwarith J, Rembert E, Tura A, Holubkov R, Barnard N (2021). A plant-based diet in overweight adults in a 16-week randomized clinical trial: The role of dietary acid load. Clinical nutrition ESPEN, 44, 150-158. (Read full article)
  64. Li W, Lipsky MS, Hon ES, Su W, Su S, He Y, Holubkov R, Sheng X, Hung (2021). Predicting all-cause 90-day hospital readmission for dental patients using machine learning methods. BDJ open, 7(1), 1. (Read full article)
  65. Kahleova H, Petersen KF, Shulman GI, Alwarith J, Rembert E, Tura A, Hill M, Holubkov R, Barnard N (2020). Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial. JAMA network open, 3(11), e2025454. (Read full article)
  66. Keenan HT, Clark AE, Holubkov R, Cox CS Jr, Ewing-Cobbs (2021). Trajectories of Children's Executive Function After Traumatic Brain Injury. JAMA network open, 4(3), e212624. (Read full article)
  67. Ward SL, VanBuren JM, Richards R, Holubkov R, Alvey JS, Jensen AR, Pollack MM, Burd R (2022). Evaluating the association between obesity and discharge functional status after pediatric injury. Journal of pediatric surgery, (Read full article)
  68. Kernan KF, Ghaloul-Gonzalez L, Vockley J, Lamb J, Hollingshead D, Chandran U, Sethi R, Park HJ, Berg RA, Wessel D, Pollack MM, Meert KL, Hall MW, Newth CJL, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Dean JM, Carcillo J (2022). Prevalence of Pathogenic and Potentially Pathogenic Inborn Error of Immunity Associated Variants in Children with Severe Sepsis. Journal of clinical immunology, 42, 350-364. (Read full article)
  69. Whitehead WE, Riva-Cambrin J, Wellons JC, Kulkarni AV, Limbrick DD, Wall VL, Rozzelle CJ, Hankinson TC, McDonald PJ, Krieger MD, Pollack IF, Tamber MS, Pindrik J, Hauptman JS, Naftel RP, Shannon CN, Chu J, Jackson EM, Browd SR, Simon TD, Holubkov R, Reeder RW, Jensen H, Koschnitzky JE, Gross P, Drake JM, Kestle JR (2021). Anterior versus posterior entry site for ventriculoperitoneal shunt insertion: a randomized controlled trial by the Hydrocephalus Clinical Research Network. Journal of neurosurgery. Pediatrics, 1-11. (Read full article)
  70. Riva-Cambrin J, Kulkarni AV, Burr R, Rozzelle CJ, Oakes WJ, Drake JM, Alvey JS, Reeder RW, Holubkov R, Browd SR, Cochrane DD, Limbrick DD, Naftel R, Shannon CN, Simon TD, Tamber MS, McDonald PJ, Wellons JC, Luerssen TG, Whitehead WE, Kestle JR (2021). Impact of ventricle size on neuropsychological outcomes in treated pediatric hydrocephalus: an HCRN prospective cohort study. Journal of neurosurgery. Pediatrics, 1-12. (Read full article)
  71. Evans LL, Jensen AR, Meert KL, VanBuren JM, Richards R, Alvey JS, Carcillo JA, McQuillen PS, Mourani PM, Nance ML, Holubkov R, Pollack MM, Burd R (2021). All body region injuries are not equal: Differences in pediatric discharge functional status based on Abbreviated Injury Scale (AIS) body regions and severity scores. Journal of pediatric surgery, 57, 739-746. (Read full article)
  72. Yates AR, Berger JT, Reeder RW, Banks R, Mourani PM, Berg RA, Carcillo JA, Carpenter T, Hall MW, Meert KL, McQuillen PS, Pollack MM, Sapru A, Notterman DA, Holubkov R, Dean JM, Wessel DL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (2022). Characterization of Inhaled Nitric Oxide Use for Cardiac Indications in Pediatric Patients. Pediatric critical care medicine, 23, 245-254. (Read full article)
  73. Qin Y, Kernan KF, Fan Z, Park HJ, Kim S, Canna SW, Kellum JA, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Banks R, Reeder RW, Holubkov R, Notterman DA, Michael Dean J, Carcillo J (2022). Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Critical care (London, England), 26(1), 128. (Read full article)
  74. Ames SG, Banks RK, Zinter MS, Fink EL, McQuillen PS, Hall MW, Zuppa A, Meert KL, Mourani PM, Carcillo JA, Carpenter T, Pollack MM, Berg RA, Mareboina M, Holubkov R, Dean JM, Notterman DA, Sapru A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) (2022). Assessment of Patient Health-Related Quality of Life and Functional Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatric critical care medicine, 23(7), e319-e328. (Read full article)
  75. Crosby L, Rembert E, Levin S, Green A, Ali Z, Jardine M, Nguyen M, Elliott P, Goldstein D, Freeman A, Bradshaw M, Holtz DN, Holubkov R, Barnard ND, Kahleova (2022). Changes in Food and Nutrient Intake and Diet Quality on a Low-Fat Vegan Diet Are Associated with Changes in Body Weight, Body Composition, and Insulin Sensitivity in Overweight Adults: A Randomized Clinical Trial. Journal of the Academy of Nutrition and Dietetics, (Read full article)
  76. Chu J, Jensen H, Holubkov R, Krieger MD, Kulkarni AV, Riva-Cambrin J, Rozzelle CJ, Limbrick DD, Wellons JC, Browd SR, Whitehead WE, Pollack IF, Simon TD, Tamber MS, Hauptman JS, Pindrik J, Naftel RP, McDonald PJ, Hankinson TC, Jackson EM, Rocque BG, Reeder R, Drake JM, Kestle JRW, Hydrocephalus Clinical Research Network., Hydrocephalus Clinical Research Network Members (2022). The Hydrocephalus Clinical Research Network quality improvement initiative: the role of antibiotic-impregnated catheters and vancomycin wound irrigation. Journal of neurosurgery. Pediatrics, 1-8. (Read full article)
  77. Williams MA, Nagel SJ, Golomb J, Jensen H, Dasher NA, Holubkov R, Edwards RJ, Luciano MG, Zwimpfer TJ, Katzen H, Moghekar A, Wisoff JH, McKhann GM, Hamilton M (2022). Safety and effectiveness of the assessment and treatment of idiopathic normal pressure hydrocephalus in the Adult Hydrocephalus Clinical Research Network. Journal of neurosurgery, 1-13. (Read full article)
  78. Maddux AB, VanBuren JM, Jensen AR, Holubkov R, Alvey JS, McQuillen P, Mourani PM, Meert KL, Burd RS, Eunice Kennedy Shriver National Institute of Child Health., Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) Assessment of Health-Related Quality of Life., Functional Outcomes after Pediatric Trauma Project Investigators (2022). Post-discharge rehabilitation and functional recovery after pediatric injury. Injury, 53(8), 2795-2803. (Read full article)
  79. Kahleova H, Berrien-Lopez R, Holtz D, Green A, Sheinberg R, Gujral H, Holubkov R, Barnard N (2021). Nutrition for Hospital Workers During a Crisis: Effect of a Plant-Based Dietary Intervention on Cardiometabolic Outcomes and Quality of Life in Healthcare Employees During the COVID-19 Pandemic. American journal of lifestyle medicine, 16(3), 399-407. (Read full article)
  80. Muram S, Isaacs AM, Sader N, Holubkov R, Fong A, Conly J, Hamilton M (2022). A standardized infection prevention bundle for reduction of CSF shunt infections in adult ventriculoperitoneal shunt surgery performed without antibiotic-impregnated catheters. Journal of neurosurgery, 1-9. (Read full article)
  81. Keenan HT, Clark A, Holubkov R, Ewing-Cobbs (2023). Longitudinal Developmental Outcomes of Infants and Toddlers With Traumatic Brain Injury. JAMA network open, 6(1), e2251195. (Read full article)
  82. Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, Zhao X, Galandi S, Setchell KD (2023). A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial. Menopause (New York, N.Y.), 30(1), 80-87. (Read full article)
  83. Horvat CM, Fabio A, Nagin DS, Banks RK, Qin Y, Park HJ, Kernan KF, Canna SW, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Reeder RW, Sward K, Holubkov R, Notterman DA, Dean JM, Carcillo JA, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networ (2022). Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatric critical care medicine, 23(12), 968-979. (Read full article)
  84. Cheung C, Kernan KF, Berg RA, Zuppa AF, Notterman DA, Pollack MM, Wessel D, Meert KL, Hall MW, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Banks RK, Reeder RW, Holubkov R, Carcillo JA, Fink EL, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networ (2023). Acute Disorders of Consciousness in Pediatric Severe Sepsis and Organ Failure: Secondary Analysis of the Multicenter Phenotyping Sepsis-Induced Multiple Organ Failure Study. Pediatric critical care medicine, (Read full article)
  85. Kahleova H, Znayenko-Miller T, Uribarri J, Schmidt N, Kolipaka S, Hata E, Holtz DN, Sutton M, Holubkov R, Barnard N (2023). Dietary advanced glycation end-products and postmenopausal hot flashes: A post-hoc analysis of a 12-week randomized clinical trial. Maturitas, 172, 32-38. (Read full article)
  86. Kahleova H, Znayenko-Miller T, Uribarri J, Holubkov R, Barnard N (2022). Dietary advanced glycation products and their associations with insulin sensitivity and body weight: A 16-week randomized clinical trial. Obesity science & practice, 9(3), 235-242. (Read full article)
  87. Dewan MC, Isaacs AM, Cools MJ, Yengo-Kahn A, Naftel RP, Jensen H, Reeder RW, Holubkov R, Haizel-Cobbina J, Riva-Cambrin J, Jafrani RJ, Pindrik JA, Jackson EM, Judy BF, Kurudza E, Pollack IF, Mcdowell MM, Hankinson TC, Staulcup S, Hauptman J, Hall K, Tamber MS, Cheong A, Warsi NM, Rocque BG, Saccomano BW, Snyder RI, Kulkarni AV, Kestle JRW, Wellons JC 3rd, Hydrocephalus Clinical Research Networ (2023). Treatment of hydrocephalus following posterior fossa tumor resection: a multicenter collaboration from the Hydrocephalus Clinical Research Network. Journal of neuro-oncology, 163(1), 123-132. (Read full article)
  88. Spivak AM, Barney BJ, Greene T, Holubkov R, Olsen CS, Bridges J, Srivastava R, Webb B, Sebahar F, Huffman A, Pacchia CF, Dean JM, Hess (2023). A Randomized Clinical Trial Testing Hydroxychloroquine for Reduction of SARS-CoV-2 Viral Shedding and Hospitalization in Early Outpatient COVID-19 Infection. Microbiology spectrum, 11(2), e0467422. (Read full article)
  89. Suttle M, Hall MW, Pollack MM, Berg RA, McQuillen PS, Mourani PM, Sapru A, Carcillo JA, Startup E, Holubkov R, Dean JM, Notterman DA, Meert K (2021). The Association between Therapeutic Alliance and Parental Health Outcomes following a Child's Death in the Pediatric Intensive Care Unit. Journal of pediatric intensive care, 12(1), 3-11. (Read full article)
  90. Ip CS, Jones DK, Weinlander E, Gudgel B, Lin A, Yazdani H, Pierce J, Holubkov R, Jensen H, Church M, Mifflin M (2023). Phase I/II randomized, double-masked, placebo-controlled study of processed amniotic fluid drops after PRK. Journal of cataract and refractive surgery, 49(3), 299-304. (Read full article)
  91. Luciano M, Holubkov R, Williams MA, Malm J, Nagel S, Moghekar A, Eklund A, Zwimpfer T, Katzen H, Hanley DF, Hamilton MG, PENS Co-investigators and AHCRN Site PI (2023). Placebo-Controlled Effectiveness of Idiopathic Normal Pressure Hydrocephalus Shunting: A Randomized Pilot Trial. Neurosurgery, 92(3), 481-489. (Read full article)
  92. Grissom CK, Holubkov R, Carpenter L, Hanna B, Jacobs JR, Jones C, Knighton AJ, Leither L, Lisonbee D, Peltan ID, Winberg C, Wolfe D, Srivastava (2023). Implementation of coordinated spontaneous awakening and breathing trials using telehealth-enabled, real-time audit and feedback for clinician adherence (TEACH): a type II hybrid effectiveness-implementation cluster-randomized trial. Implementation science, 18(1), 45. (Read full article)
  93. VanBuren JM, Hall M, Zuppa AF, Mourani PM, Carcillo J, Dean JM, Watt K, Holubkov (2023). The Design of Nested Adaptive Clinical Trials of Multiple Organ Dysfunction Syndrome Children in a Single Study. Pediatric critical care medicine, 24(12), e635-e646. (Read full article)
  94. Podd BS, Banks RK, Reeder R, Holubkov R, Carcillo J, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Shanley T, Cornell T, Harrison RE, Zuppa AF, Sward K, Dean JM, Randolph AG, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networ (2023). Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children. Critical care medicine, (Read full article)
  95. Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, Hata E, Znayenko-Miller T, Holubkov R, Barnard N (2023). A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis. Complementary therapies in medicine, 79, 103002. (Read full article)
  96. Kahleova H, Brennan H, Znayenko-Miller T, Holubkov R, Barnard N (2023). Does diet quality matter? A secondary analysis of a randomized clinical trial. European journal of clinical nutrition, (Read full article)
  97. Kirschenbaum MD, Hu KS, Ip CS, Lin A, Pierce J, Holubkov R, Jensen H, Mifflin M (2024). One-Year Results of a Phase I/II Randomized, Double-Masked, Placebo-Controlled Study of Processed Amniotic Fluid Drops After PRK. Cornea, 43(8), 955-960. (Read full article)
  98. Ravindra VM, Riva-Cambrin J, Jensen H, Whitehead WE, Kulkarni AV, Limbrick DD, Wellons JC, Naftel RP, Rozzelle CJ, Rocque BG, Pollack IF, McDowell MM, Tamber MS, Hauptman JS, Browd SR, Pindrik J, Isaacs AM, McDonald PJ, Hankinson TC, Jackson EM, Chu J, Krieger MD, Simon TD, Strahle JM, Holubkov R, Reeder R, Kestle JR (2024). Comparing ventriculoatrial and ventriculopleural shunts in pediatric hydrocephalus: a Hydrocephalus Clinical Research Network study. Journal of neurosurgery. Pediatrics, 34(4), 1-10. (Read full article)
  99. Steinberg BA, Holubkov R, Deering T, Groh CA, Mittal S, Kennedy R, Pokharel P, Perez M, Savona S, Verma N, Watt K, Piccini JP, Bunch T (2024). Expedited loading with intravenous sotalol is safe and feasible-primary results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry. Heart rhythm, 21(7), 1134-1142. (Read full article)
  100. Cabler SS, Storch GA, Weinberg JB, Walton AH, Brengel-Pesce K, Aldewereld Z, Banks RK, Cheynet V, Reeder R, Holubkov R, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Cornell T, Harrison RE, Dean JM, Carcillo J (2024). Viral DNAemia and DNA Virus Seropositivity and Mortality in Pediatric Sepsis. JAMA network open, 7(2), e240383. (Read full article)
  101. Kahleova H, Znayenko-Miller T, Motoa G, Eng E, Prevost A, Uribarri J, Holubkov R, Barnard N (2024). Dietary advanced glycation end-products and their associations with body weight on a Mediterranean diet and low-fat vegan diet: a randomized, cross-over trial. Frontiers in nutrition, 11, 1426642. (Read full article)
  102. Aldewereld Z, Connolly B, Banks RK, Reeder R, Holubkov R, Berg RA, Wessel D, Pollack MM, Meert K, Hall M, Newth C, Lin JC, Doctor A, Cornell T, Harrison RE, Zuppa AF, Dean JM, Carcillo J (2024). Risk factors for prolonged infection and secondary infection in pediatric severe sepsis. Infection, (Read full article)
  103. Kahleova H, Znayenko-Miller T, Smith K, Khambatta C, Barbaro R, Sutton M, Holtz DN, Sklar M, Pineda D, Holubkov R, Barnard N (2024). Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: A 12-Week Randomized Clinical Trial. Clinical diabetes, 42(3), 419-427. (Read full article)
  104. Yellepeddi VK, Ismail M, Bunch TJ, Deering TF, Holubkov R, Kennedy R, Mittal S, Perez M, Piccini JP, Pokharel P, Savona S, Verma N, Steinberg B, Watt (2025). Population Pharmacokinetics and Pharmacodynamics of Sotalol Following Expedited Intravenous Loading in Patients With Atrial Arrhythmias. CPT, (Read full article)
  105. Brennan H, Znayenko-Miller T, Sutton M, Holubkov R, Barnard ND, Kahleova (2024). Diet quality, body weight, and postmenopausal hot flashes: a secondary analysis of a randomized clinical trial. BMC women's health, 24(1), 620. (Read full article)
  106. VanBuren JM, Yeatts SD, Holubkov R, Moler FW, Topjian A, Page K, Clevenger RG, Meurer W (2024). The Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP): Statistical Methods Planned in the Bayesian, Adaptive, Duration Finding Trial. Pediatric critical care medicine, 26(2), e227-e236. (Read full article)
  107. Kahleova H, Sutton M, Maracine C, Nichols D, Monsivais P, Holubkov R, Barnard N (2024). Food Costs of a Low-Fat Vegan Diet vs a Mediterranean Diet: A Secondary Analysis of a Randomized Clinical Trial. JAMA network open, 7(11), e2445784. (Read full article)
  108. Kahleova H, Znayenko-Miller T, Jayaraman A, Motoa G, Chiavaroli L, Holubkov R, Barnard N (2025). Vegan diet, processed foods, and body weight: a secondary analysis of a randomized clinical trial. Nutrition & metabolism, 22(1), 21. (Read full article)
  109. Isaacs AM, Shannon CN, Browd SR, Hauptman JS, Holubkov R, Jensen H, Kulkarni AV, McDonald PJ, McDowell MM, Naftel RP, Nunn N, Pindrik J, Pollack IF, Reeder R, Riva-Cambrin J, Rozzelle CJ, Rocque BG, Strahle JM, Tamber MS, Whitehead WE, Kestle JRW, Limbrick DD, Wellons J (2025). Neurodevelopmental outcomes of permanent and temporary CSF diversion in posthemorrhagic hydrocephalus: a Hydrocephalus Clinical Research Network study. Journal of neurosurgery. Pediatrics, 1-12. (Read full article)
  110. Barnard ND, Levin S, Crosby L, Flores R, Holubkov R, Kahleova (2022). A Randomized, Crossover Trial of a Nutritional Intervention for Rheumatoid Arthritis. American journal of lifestyle medicine, 19(2), 266-275. (Read full article)
  111. Rocque BG, Jensen H, Reeder RW, Rozzelle CJ, Kulkarni AV, Pollack IF, McDowell MM, Naftel RP, Jackson EM, Whitehead WE, Pindrik JA, Isaacs AM, Strahle JM, McDonald PJ, Tamber MS, Hankinson TC, Browd SR, Hauptman JS, Krieger MD, Chu J, Riva-Cambrin J, Limbrick DD, Holubkov R, Kestle JRW, Wellons J (2025). Racial disparities in hydrocephalus mortality and shunt revision: a study from the Hydrocephalus Clinical Research Network. Journal of neurosurgery. Pediatrics, 1-9. (Read full article)

Review

  1. Whitehead WE, Rozzelle CJ, Riva-Cambrin J, Wellons JC III, Kulkarni A, Hankinson T, McDonald P, Krieger M, Pollack IF, Tamber MS, Pindrick JA, Limbrick D, Hauptman JS, Naftel RP, Jackson E, Browd S, Holubkov R, Reeder R, Wall V, Jensen H, Koschnitsky J, Gross P, Drake JM, Kestle JRW, Hydrocephalus Clinical Research Networ (2022). (Read full article)

Letter

  1. Kahleova H, Sutton M, Maracine C, Nichols D, Monsivais P, Holubkov R, Barnard N (2023). Vegan Diet and Food Costs Among Adults With Overweight: A Secondary Analysis of a Randomized Clinical Trial. JAMA network open, 6(9), e2332106. (Read full article)

Other

  1. Millar MM, Olson LM, VanBuren JM, Richards R, Pollack MM, Holubkov R, Berg RA, Carcillo JA, McQuillen PS, Meert KL, Mourani PM, Burd R (2021). Incentive delivery timing and follow-up survey completion in a prospective cohort study of injured children: a randomized experiment comparing prepaid and postpaid incentives. BMC medical research methodology, 21(1), 233. (Read full article)