Jared P. Rutter

Jared P. Rutter, PhD

Languages spoken: English

Academic Information

Departments Primary - Biochemistry

Lab

Research Interests

  • Metabolism
  • Metabolism Regulation
  • Cell Signaling
  • Cell Communication

Jared Rutter, PhD, is a Distinguished Professor in the Department of Biochemistry at the University of Utah and Co-Leader of the Genomics, Epigenetics and Metabolism Program at Huntsman Cancer Institute. He is also Co-Director of the Center for Metabolic Health.

The Rutter lab studies how cells sense and respond to metabolic demands for optimal function.

Rutter received a bachelor's degree from Brigham Young University, Utah, and a PhD from the University of Texas Southwestern Medical Center at Dallas.

Education History

Postdoctoral Fellowship University of Texas Southwestern Medical Center
 Postdoctoral Fellow
Doctoral Training University of Texas Southwestern Medical Center, Steven L. McKnight, advisor
 PhD
Undergraduate Brigham Young University
 BS

Selected Publications

Journal Article

  1. Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeo-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Prez J, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS (2024). Direct mitochondrial import of lactate supports resilient carbohydrate oxidation. bioRxiv.
  2. Toshniwal AG, Lam G, Bott AJ, Cluntun AA, Skabelund R, Nam HJ, Wisidagama DR, Thummel CS, Rutter J (2024). The fate of pyruvate dictates cell growth by modulating cellular redox potential. bioRxiv and eLife.
  3. Visker JR, Cluntun AA, Velasco-Silva JN, Eberhardt DR, Cedeo-Rosario L, Shankar TS, Hamouche R, Ling J, Kwak H, Hillas JY, Aist I, Tseliou E, Navankasattusas S, Chaudhuri D, Ducker GS, Drakos SG, Rutter J (2024). Enhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart. JCI Insight, 9(17).
  4. Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Brothwell MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K (2024). Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism. J Clin Invest, 134(11).
  5. Kanth P, Hazel MW, Schell JC, Rutter J, Yao R, Mills AP, Delker DA (2024). Evaluation of EGFR and COX pathway inhibition in human colon organoids of serrated polyposis and other hereditary cancer syndromes. Fam Cancer.
  6. Ouyang Y, Jeong MY, Cunningham CN, Berg JA, Toshniwal AG, Hughes CE, Seiler K, Van Vranken JG, Cluntun AA, Lam G, Winter JM, Akdogan E, Dove KK, Nowinski SM, West M, Odorizzi G, Gygi SP, Dunn CD, Winge DR, Rutter J (2024). Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. Elife, 13.
  7. Song C, Valeri A, Song F, Ji X, Liao X, Marmo T, Seeley R, Rutter J, Long F (2023). Sexual dimorphism of osteoclast reliance on mitochondrial oxidation of energy substrates in the mouse. JCI Insight, 8(24).
  8. Li J, Richmond B, Cluntun AA, Bia R, Walsh MA, Shaw K, Symons JD, Franklin S, Rutter J, Funai K, Shaw RM, Hong T (2023). Cardiac gene therapy treats diabetic cardiomyopathy and lowers blood glucose. JCI Insight, 8(18).
  9. Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Anandh Babu PV, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar BA, Summers SA (2023). Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk. Gastroenterology, 165(5), 1136-1150.
  10. Mocholi E, Russo L, Gopal K, Ramstead AG, Hochrein SM, Vos HR, Geeven G, Adegoke AO, Hoekstra A, van Es RM, Pittol JR, Vastert S, Rutter J, Radstake T, van Loosdregt J, Berkers C, Mokry M, Anderson CC, OConnell RM, Vaeth M, Ussher J, Burgering BMT, Coffer PJ (2023). Pyruvate metabolism controls chromatin remodeling during CD4(+) T cell activation. Cell Rep, 42(6), 112583.
  11. Cluntun AA, Rutter J (2023). The secret life of lactate: A novel cell-cycle regulatory mechanism. Cell Metab, 35(5), 730-732.
  12. Granath-Panelo M, Krook A, Rutter J, Kajimura S (2023). On the cutting edge: perspectives in bioenergetics. Nat Rev Endocrinol, 19(5), 250-251.
  13. Berg JA, Zhou Y, Ouyang Y, Cluntun AA, Waller TC, Conway ME, Nowinski SM, Van Ry T, George I, Cox JE, Wang B, Rutter J (2023). Metaboverse enables automated discovery and visualization of diverse metabolic regulatory patterns. Nat Cell Biol, 25(4), 616-625.
  14. Hicks KG, Cluntun AA, Schubert HL, Hackett SR, Berg JA, Leonard PG, Ajalla Aleixo MA, Zhou Y, Bott AJ, Salvatore SR, Chang F, Blevins A, Barta P, Tilley S, Leifer A, Guzman A, Arok A, Fogarty S, Winter JM, Ahn HC, Allen KN, Block S, Cardoso IA, Ding J, Dreveny I, Gasper WC, Ho Q, Matsuura A, Palladino MJ, Prajapati S, Sun P, Tittmann K, Tolan DR, Unterlass J, VanDemark AP, Vander Heiden MG, Webb BA, Yun CH, Zhao P, Wang B, Schopfer FJ, Hill CP, Nonato MC, Muller FL, Cox JE, Rutter J (2023). Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase. Science, 379(6636), 996-1003.
  15. Webb BD, Nowinski SM, Solmonson A, Ganesh J, Rodenburg RJ, Leandro J, Evans A, Vu HS, Naidich TP, Gelb BD, DeBerardinis RJ, Rutter J, Houten SM (2023). Recessive pathogenic variants in MCAT cause combined oxidative phosphorylation deficiency. Elife, 12.
  16. Kidwell CU, Casalini JR, Pradeep S, Scherer SD, Greiner D, Bayik D, Watson DC, Olson GS, Lathia JD, Johnson JS, Rutter J, Welm AL, Zangle TA, Roh-Johnson M (2023). Transferred mitochondria accumulate reactive oxygen species, promoting proliferation. Elife, 12.
  17. Johnson JM, Peterlin AD, Balderas E, Sustarsic EG, Maschek JA, Lang MJ, Jara-Ramos A, Panic V, Morgan JT, Villanueva CJ, Sanchez A, Rutter J, Lodhi IJ, Cox JE, Fisher-Wellman KH, Chaudhuri D, Gerhart-Hines Z, Funai K (2023). Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis. Sci Adv, 9(8), eade7864.
  18. Bebarta VS, Shi X, Zheng S, Hendry-Hofer TB, Severance CC, Behymer MM, Boss GR, Mahon S, Brenner M, Knipp GT, Davisson VJ, Peterson RT, MacRae CA, Rutter J, Gerszten RE, Nath AK (2022). Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication. Toxicol Sci, 191(1), 90-105.
  19. Winter JM, Fresenius HL, Cunningham CN, Wei P, Keys HR, Berg J, Bott A, Yadav T, Ryan J, Sirohi D, Tripp SR, Barta P, Agarwal N, Letai A, Sabatini DM, Wohlever ML, Rutter J (2022). Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction. Elife, 11.
  20. Wei P, Bott AJ, Cluntun AA, Morgan JT, Cunningham CN, Schell JC, Ouyang Y, Ficarro SB, Marto JA, Danial NN, DeBerardinis RJ, Rutter J (2022). Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway. Sci Adv, 8(39), eabq0117.
  21. Nielson JR, Nath AK, Doane KP, Shi X, Lee J, Tippetts EG, Saha K, Morningstar J, Hicks KG, Chan A, Zhao Y, Kelly A, Hendry-Hofer TB, Witeof A, Sips PY, Mahon S, Bebarta VS, Davisson VJ, Boss GR, Rutter J, MacRae CA, Brenner M, Gerszten RE, Peterson RT (2022). Glyoxylate protects against cyanide toxicity through metabolic modulation. Sci Rep, 12(1), 4982.
  22. De La Rossa A, Laporte MH, Astori S, Marissal T, Montessuit S, Sheshadri P, Ramos-Fernndez E, Mendez P, Khani A, Quairiaux C, Taylor EB, Rutter J, Nunes JM, Carleton A, Duchen MR, Sandi C, Martinou JC (2022). Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency. Elife, 11.
  23. Nuebel E, Morgan JT, Fogarty S, Winter JM, Lettlova S, Berg JA, Chen YC, Kidwell CU, Maschek JA, Clowers KJ, Argyriou C, Chen L, Wittig I, Cox JE, Roh-Johnson M, Braverman N, Bonkowsky J, Gygi SP, Rutter J (2021). The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. EMBO Rep, 22(10), e51991.
  24. Shimura D, Nuebel E, Baum R, Valdez SE, Xiao S, Warren JS, Palatinus JA, Hong T, Rutter J, Shaw RM (2021). Protective mitochondrial fission induced by stress-responsive protein GJA1-20k. Elife, 10.
  25. Hao Q, Heo JM, Nocek BP, Hicks KG, Stoll VS, Remarcik C, Hackett S, LeBon L, Jain R, Eaton D, Rutter J, Wong YL, Sidrauski C (2021). Sugar phosphate activation of the stress sensor eIF2B. Nat Commun, 12(1), 3440.
  26. Ouyang Y, Bott AJ, Rutter J (2021). Maestro of the SereNADe: SLC25A51 Orchestrates Mitochondrial NAD(). Trends Biochem Sci, 46(5), 348-350.
  27. Bezerra GA, Holenstein A, Foster WR, Xie B, Hicks KG, Brer C, Lutz S, Mukherjee A, Sarkar D, Bhattacharya D, Rutter J, Talukdar A, Brown PJ, Luo M, Shi L, Froese DS, Yue WW (2021). Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain. Biochimie, 183, 100-107.
  28. Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG (2020). The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab, 33(3), 629-648.e10.
  29. McKean WB, Toshniwal AG, Rutter J (2021). A time to build and a time to burn: glucose metabolism for every season. Mol Cell, 81(4), 642-644.
  30. Fogarty S, Ouyang Y, Li L, Chen YC, Rane H, Manoni F, Parra KJ, Rutter J, Harran PG (2020). Callyspongiolide Is a Potent Inhibitor of the Vacuolar ATPase. J Nat Prod, 83(11), 3381-3386.
  31. Wang Z, Ning T, Song A, Rutter J, Wang QA, Jiang L (2020). Chronic cold exposure enhances glucose oxidation in brown adipose tissue. EMBO Rep, 21(11), e50085.
  32. Zhang Y, Taufalele PV, Cochran JD, Robillard-Frayne I, Marx JM, Soto J, Rauckhorst AJ, Tayyari F, Pewa AD, Gray LR, Teesch LM, Puchalska P, Funari TR, McGlauflin R, Zimmerman K, Kutschke WJ, Cassier T, Hitchcock S, Lin K, Kato KM, Stueve JL, Haff L, Weiss RM, Cox JE, Rutter J, Taylor EB, Crawford PA, Lewandowski ED, Des Rosiers C, Abel ED (2020). Mitochondrial pyruvate carriers are required for myocardial stress adaptation. Nat Metab, 2(11), 1248-1264.
  33. Nowinski SM, Solmonson A, Rusin SF, Maschek JA, Bensard CL, Fogarty S, Jeong MY, Lettlova S, Berg JA, Morgan JT, Ouyang Y, Naylor BC, Paulo JA, Funai K, Cox JE, Gygi SP, Winge DR, DeBerardinis RJ, Rutter J (2020). Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria. Elife, 9.
  34. Panic V, Pearson S, Banks J, Tippetts TS, Velasco-Silva JN, Lee S, Simcox J, Geoghegan G, Bensard CL, van Ry T, Holland WL, Summers SA, Cox J, Ducker GS, Rutter J, Villanueva CJ (2020). Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. Elife, 9.
  35. Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG (2020). The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation, 142(3), 259-274.
  36. Bezerra GA, Foster WR, Bailey HJ, Hicks KG, Sauer SW, Dimitrov B, McCorvie TJ, Okun JG, Rutter J, Klker S, Yue WW (2020). Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism. IUCrJ, 7(Pt 4), 693-706.
  37. Ekiz HA, Ramstead AG, Lee SH, Nelson MC, Bauer KM, Wallace JA, Hu R, Round JL, Rutter J, Drummond MJ, Rao DS, OConnell RM (2020). T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation. J Immunol, 204(8), 2064-2075.
  38. Swiatek W, Parnell KM, Nickols GA, Scharschmidt BF, Rutter J (2020). Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. Hepatol Commun, 4(5), 696-707.
  39. Ramstead AG, Wallace JA, Lee SH, Bauer KM, Tang WW, Ekiz HA, Lane TE, Cluntun AA, Bettini ML, Round JL, Rutter J, OConnell RM (2018). Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development. Cell Rep, 30(9), 2889-2899.e6.
  40. Bensard CL, Wisidagama DR, Olson KA, Berg JA, Krah NM, Schell JC, Nowinski SM, Fogarty S, Bott AJ, Wei P, Dove KK, Tanner JM, Panic V, Cluntun A, Lettlova S, Earl CS, Namnath DF, Vzquez-Arregun K, Villanueva CJ, Tantin D, Murtaugh LC, Evason KJ, Ducker GS, Thummel CS, Rutter J (2019). Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. Cell Metab, 31(2), 284-300.e7.
  41. Berg JA, Belyeu JR, Morgan JT, Ouyang Y, Bott AJ, Quinlan AR, Gertz J, Rutter J (2020). XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data. PLoS Comput Biol, 16(1), e1007625.
  42. Waller TC, Berg JA, Lex A, Chapman BE, Rutter J (2018). Compartment and hub definitions tune metabolic networks for metabolomic interpretations. Gigascience, 9(1).
  43. Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brs LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K (2019). Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv, 5(9), eaax8352.
  44. Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA (2019). Targeting a ceramide double bond improves insulin resistance and hepatic steatosis. Science, 365(6451), 386-392.
  45. Kikani CK, Wu X, Fogarty S, Kang SAW, Dephoure N, Gygi SP, Sabatini DM, Rutter J (2019). Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program. Proc Natl Acad Sci U S A, 116(21), 10382-10391.
  46. Vzquez-Arregun K, Bensard C, Schell JC, Swanson E, Chen X, Rutter J, Tantin D (2019). Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy. PLoS Genet, 15(5), e1007687.
  47. Jeong MY, Rutter J, Chou DH (2019). Display of Single-Chain Insulin-like Peptides on a Yeast Surface. Biochemistry, 58(3), 182-188.
  48. Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA (2018). Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning. PLoS One, 13(6), e0193889.
  49. X Wu, D Romero, WI Swaitek, I Dorweiler, CK Kikani, H Savic, BS Zweifel, J McKearn, JT Blitzer, GA Nickols, J Rutter (2014). PAS Kinase drives lipogenesis through SREPB-1 maturation. Cell Rep, 8(242).
  50. Na U, Yu W, Cox J, Bricker DK, Brockmann K, Rutter J, Thummel CS, Winge DR (2014). The LYR factors SDHAF1 and SDHAF3 mediate maturation of the iron-sulfur subunit of succinate dehydrogenase. Cell Metab, 20(2), 253-66.
  51. Van Vranken JG, Bricker DK, Dephoure N, Gygi SP, Cox JE, Thummel CS, Rutter J (2014). SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration. Cell Metab, 20(2), 241-52.
  52. Chen YC, Umanah GK, Dephoure N, Andrabi SA, Gygi SP, Dawson TM, Dawson VL, Rutter J (2014). Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins. EMBO J, 33(14), 1548-64.
  53. Wu X, Romero D, Swiatek WI, Dorweiler I, Kikani CK, Sabic H, Zweifel BS, McKearn J, Blitzer JT, Nickols GA, Rutter J (2014). PAS kinase drives lipogenesis through SREBP-1 maturation. Cell Rep, 8(1), 242-55.
  54. Chen YC, Rutter J (2014). Pressing mitochondrial genetics forward. Cell Rep, 7(3), 599-600.
  55. Semache M, Zarrouki B, Fontes G, Fogarty S, Kikani C, Chawki MB, Rutter J, Poitout V (2013). Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3beta in pancreatic beta-cells. J Biol Chem, 288(34), 24825-33.
  56. Heo JM, Nielson JR, Dephoure N, Gygi SP, Rutter J (2013). Intramolecular interactions control Vms1 translocation to damaged mitochondria. Mol Biol Cell, 24(9), 1263-73.
  57. Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J (2012). A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science, 337(6090), 96-100.
  58. Chen YC, Taylor EB, Dephoure N, Heo JM, Tonhato A, Papandreou I, Nath N, Denko NC, Gygi SP, Rutter J (2012). Identification of a protein mediating respiratory supercomplex stability. Cell Metab, 15(3), 348-60.
  59. Cardon CM, Beck T, Hall MN, Rutter J (2012). PAS kinase promotes cell survival and growth through activation of Rho1. Sci Signal, 5(209), ra9.
  60. Orsak T, Smith TL, Eckert D, Lindsley JE, Borges CR, Rutter J (2012). Revealing the allosterome: systematic identification of metabolite-protein interactions. Biochemistry, 51(1), 225-32.
  61. Semplici F, Vaxillaire M, Fogarty S, Semache M, Bonnefond A, Fonts G, Philippe J, Meur G, Diraison F, Sessions RB, Rutter J, Poitout V, Froguel P, Rutter GA (2011). Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion. J Biol Chem, 286(51), 44005-44014.

Review

  1. Baker SA, Rutter J (2023). Metabolites as signalling molecules. [Review]. Nat Rev Mol Cell Biol, 24(5), 355-374.
  2. Winter JM, Yadav T, Rutter J (2022). Stressed to death: Mitochondrial stress responses connect respiration and apoptosis in cancer. [Review]. Mol Cell, 82(18), 3321-3332.
  3. Cable J, Pourqui O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutirrez-Prez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H (2021). Metabolic decisions in development and disease-a Keystone Symposia report. [Review]. Ann N Y Acad Sci, 1506(1), 55-73.
  4. Cunningham CN, Rutter J (2020). 20,000 picometers under the OMM: diving into the vastness of mitochondrial metabolite transport. [Review]. EMBO Rep, 21(5), e50071.
  5. Funai K, Summers SA, Rutter J (2020). Reign in the membrane: How common lipids govern mitochondrial function. [Review]. Curr Opin Cell Biol, 63, 162-173.
  6. Pagliarini DJ, Rutter J (2013). Hallmarks of a new era in mitochondrial biochemistry. [Review]. Genes Dev, 27(24), 2615-27.
  7. Cardon CM, Rutter J (2012). PAS kinase: integrating nutrient sensing with nutrient partitioning. [Review]. Semin Cell Dev Biol, 23(6), 626-30.
  8. Tantin D, Rutter J (2012). Proliferation and metabolism: it's as easy as APC. [Review]. Cell Metab, 15(4), 413-4.
  9. Heo JM, Rutter J (2011). Ubiquitin-dependent mitochondrial protein degradation. [Review]. Int J Biochem Cell Biol, 43(10), 1422-6.
  10. Taylor EB, Rutter J (2011). Mitochondrial quality control by the ubiquitin-proteasome system. [Review]. Biochem Soc Trans, 39(5), 1509-13.
  11. Lindsley JE, Rutter J (2004). Nutrient sensing and metabolic decisions. [Review]. Comp Biochem Physiol B Biochem Mol Biol, 139(4), 543-59.

Patent

  1. Rutter J (2012). Compositions and Methods for Modulating Mitochondrial Pyruvate Carrier Activity (Provisional Patent).
  2. Rutter J (2009). Sdh5 in diagnostic applications in paraganglioma and related tumors (Provisional Patent).
  3. Rutter J (2002). Isolation, Identification and Characterization of PAS kinase. U.S. Patent No. 6,319,679. Washington, D.C.:U.S. Patent and Trademark Office.