Guilherme Del Fiol

Guilherme Del Fiol, MD, PhD, FACMI

Languages spoken: English, Portuguese, Italian

Academic Information

Departments Primary - Biomedical Informatics

Research Interests

  • Clinical Decision Support Systems
  • Knowledge Management, Clinical
  • Health Information Standards Development and Use
  • Controlled Standard Terminologies

Dr. Guilherme Del Fiol earned his MD from the University of Sao Paulo, Brazil; his MS in Information Systems from the Catholic University of Parana, Brazil; and his PhD in Biomedical Informatics from the University of Utah. He is currently Professor and Vice-Chair for Research in the University of Utah’s Department of Biomedical Informatics. Prior to the University of Utah, Dr. Del Fiol held positions in Clinical Knowledge Management at Intermountain Healthcare and as faculty at the Duke Community and Family Medicine Department. Since 2008, he has served as an elected co-chair of the Clinical Decision Support Work Group at Health Level International (HL7). He is also an elected Fellow of the American College of Medical Informatics (ACMI) and a member of the Comprehensive Cancer Center at Huntsman Cancer Institute.

Dr. Del Fiol's research interests are in the design, development, evaluation, and dissemination of standards-based clinical decision support and digital health interventions. He has been focusing particularly on interventions to improve cancer prevention and reduce health disparities. He is the lead author of the HL7 Infobutton Standard and the project lead for OpenInfobutton, an open source suite of infobutton tools and Web services, which is in production use at several healthcare organizations throughout the United States, including Intermountain Healthcare, Duke University, and the Veterans Health Administration (VHA). His research has been funded by various sources including the National Library of Medicine (NLM), National Cancer Institute (NCI), AHRQ, CDC, CMS, and PCORI.


“Health informatics combines the two areas that appeal to me the most, health care and technology. I feel this combination provides me with greater potential to improve the quality of health care than through direct patient care. It is rewarding knowing that my research work has practical and direct implications in the daily routine of clinicians and ultimately in people’s health. This is a major motivation for me to come to work every day.”

Google Scholar: http://scholar.google.com/citations?user=C-q_xHcAAAAJ&hl=en&oi=ao

My Bibliography in PubMed: https://www.ncbi.nlm.nih.gov/myncbi/guilherme.del%20fiol.1/bibliography/public/


Twitter: @guilhermeDFiol

Research Statement

Dr. Del Fiol is interested in the design, development, evaluation and dissemination of standards-based clinical informatics and clinical decision support (CDS) interventions to improve the quality, safety, and value of health care. He is especially interested in clinical decision support interventions for cancer prevention and screening. He is also interested in the development and implementation of health IT standards to promote wide dissemination of CDS interventions across health care organizations and EHR platforms.

Education History

Doctoral Training University of Utah, Department of Biomedical Informatics
 PhD
Catholic University of Paraná, School of Computer Science
 MS
Other Training School of Public Health, University of São Paulo
 Certificate
University of São Paulo
 Resident
Professional Medical University of São Paulo
 MD

Selected Publications

Journal Article

  1. Cheville AL, Patil C, Boyd AD, Crofford L, Dailey D, de Martelly V, Del Fiol G, Ezenwa M, Faurot K, Knisely M, McLeod K, Morone N, OBrien E, Gonzalez-Guarda R, Sluka K, Staman K, Thackeray A, Zigler C, Schlaeger J (2024). Special Section on Patient-Reported Outcomes and Informatics: Collection of Patient-Reported Outcome Measures in Rural and Underserved Populations. Appl Clin Inform. (Read full article)
  2. Schlechter CR, Kuzmenko TV, Orleans B, Wirth J, Kaphingst KA, Gibson B, Kawamoto K, Siaperas T, Pruhs A, Dinkins CP, Greene T, Zhang Y, Chipman JJ, Friedrichs M, Lam CY, Pierce JH, Borsato EP, Cornia RC, Stevens L, Martinez A, Bradshaw RL, Hess R, Fiol GD, Wetter DW (2024). Reach and Engagement With Population Health Management Interventions to Address COVID-19 Among Safety-Net Health Care Systems. Am J Public Health, 114(11), 1207-1211. (Read full article)
  3. Gomez F, Danos AM, Del Fiol G, Madabhushi A, Tiwari P, McMichael JF, Bakas S, Bian J, Davatzikos C, Fertig EJ, Kalpathy-Cramer J, Kenney J, Savova GK, Yetisgen M, Van Allen EM, Warner JL, Prior F, Griffith M, Griffith OL (2024). A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges. Cancer Discov, 14(10), 1774-1778. (Read full article)
  4. Kaphingst KA, Kohlmann WK, Lorenz Chambers R, Bather JR, Goodman MS, Bradshaw RL, Chavez-Yenter D, Colonna SV, Espinel WF, Everett JN, Flynn M, Gammon A, Harris A, Hess R, Kaiser-Jackson L, Lee S, Monahan R, Schiffman JD, Volkmar M, Wetter DW, Zhong L, Mann DM, Ginsburg O, Sigireddi M, Kawamoto K, Del Fiol G, Buys SS (2024). Uptake of Cancer Genetic Services for Chatbot vs Standard-of-Care Delivery Models: The BRIDGE Randomized Clinical Trial. JAMA Netw Open, 7(9), e2432143. (Read full article)
  5. Coen E, Del Fiol G, Kaphingst KA, Borsato E, Shannon J, Smith HS, Masino A, Allen CG (2024). Chatbot for the Return of Positive Genetic Screening Results for Hereditary Cancer Syndromes: a Prompt Engineering Study. Res Sq. (Read full article)
  6. Afiaz A, Ivanov AA, Chamberlin J, Hanauer D, Savonen CL, Goldman MJ, Morgan M, Reich M, Getka A, Holmes A, Pati S, Knight D, Boutros PC, Bakas S, Caporaso JG, Del Fiol G, Hochheiser H, Haas B, Schloss PD, Eddy JA, Albrecht J, Fedorov A, Waldron L, Hoffman AM, Bradshaw RL, Leek JT, Wright C (2023). Best practices to evaluate the impact of biomedical research software-metric collection beyond citations. Bioinformatics, 40(8). (Read full article)
  7. Kukhareva PV, Li H, Caverly TJ, Fagerlin A, Del Fiol G, Hess R, Zhang Y, Butler JM, Schlechter C, Flynn MC, Reddy C, Choi J, Balbin C, Warner IA, Warner PB, Nanjo C, Kawamoto K (2024). Lung Cancer Screening Before and After a Multifaceted Electronic Health Record Intervention: A Nonrandomized Controlled Trial. JAMA Netw Open, 7(6), e2415383. (Read full article)
  8. Payne VL, Sattar U, Wright M, Hill E, Butler JM, Macpherson B, Jeppesen A, Del Fiol G, Madaras-Kelly K (2024). Clinician perspectives on how situational context and augmented intelligence design features impact perceived usefulness of sepsis prediction scores embedded within a simulated electronic health record. J Am Med Inform Assoc. (Read full article)
  9. Asare AO, Stagg BC, Sharareh N, Stipelman C, Del Fiol G, Smith JD (2024). Vision Loss in Children from Immigrant and Nonimmigrant Households: Evidence from the National Survey of Children's Health 2018-2020. J Immigr Minor Health, 26(5), 813-822. (Read full article)
  10. Stagg BC, Schlechter CR, Del Fiol G (2024). The Digital Divide in Eye Health Care Delivery. JAMA Ophthalmol. (Read full article)
  11. Johnson D, Del Fiol G, Kawamoto K, Romagnoli KM, Sanders N, Isaacson G, Jenkins E, Williams MS (2024). Genetically guided precision medicine clinical decision support tools: a systematic review. J Am Med Inform Assoc, 31(5), 1183-1194. (Read full article)
  12. Del Fiol G, Orleans B, Kuzmenko TV, Chipman J, Greene T, Martinez A, Wirth J, Meads R, Kaphingst KK, Gibson B, Kawamoto K, King AJ, Siaperas T, Hughes S, Pruhs A, Pariera Dinkins C, Lam CY, Pierce JH, Benson R, Borsato EP, Cornia R, Stevens L, Bradshaw RL, Schlechter CR, Wetter DW (2024). SCALE-UP II: protocol for a pragmatic randomised trial examining population health management interventions to increase the uptake of at-home COVID-19 testing in community health centres. BMJ Open, 14(3), e081455. (Read full article)
  13. Lario R, Soley R, White S, Butler J, Del Fiol G, Eilbeck K, Huff S, Kawamoto K (2024). The Business Process Management for Healthcare (BPM+ Health) Consortium: motivation, methodology, and deliverables for enabling clinical knowledge interoperability (CKI). J Am Med Inform Assoc, 31(4), 797-808. (Read full article)
  14. Fritz JM, Gibson B, Wetter DW, Del Fiol G, Solis V, Ford I, Lundberg K, Thackeray A (2024). Use of implementation mapping in the planning of a hybrid type 1 pragmatic clinical trial: the BeatPain Utah study. Implement Sci Commun, 5(1), 3. (Read full article)
  15. Harris A, Bather JR, Kawamoto K, Fiol GD, Bradshaw RL, Kaiser-Jackson L, Monahan R, Kohlmann W, Liu F, Ginsburg O, Goodman MS, Kaphingst KA (2024). Determinants of Breast Cancer Screening Adherence During the COVID-19 Pandemic in a Cohort at Increased Inherited Cancer Risk in the United States. Cancer Control, 31, 10732748241272727. (Read full article)
  16. Zigler CK, Adeyemi O, Boyd AD, Braciszewski JM, Cheville A, Cuthel AM, Dailey DL, Del Fiol G, Ezenwa MO, Faurot KR, Justice M, Ho PM, Lawrence K, Marsolo K, Patil CL, Paek H, Richesson RL, Staman KL, Schlaeger JM, OBrien EC (2023). Collecting patient-reported outcome measures in the electronic health record: Lessons from the NIH pragmatic trials Collaboratory. Contemp Clin Trials, 107426. (Read full article)
  17. Bradshaw RL, Kawamoto K, Bather JR, Goodman MS, Kohlmann WK, Chavez-Yenter D, Volkmar M, Monahan R, Kaphingst KA, Del Fiol G (2023). Enhanced Family History-Based Algorithms Increase the Identification of Individuals Meeting Criteria for Genetic Testing of Hereditary Cancer Syndromes but Would Not Reduce Disparities on Their Own. J Biomed Inform, 149, 104568. (Read full article)
  18. Schlechter CR, Del Fiol G, Jones DR, Orleans B, Gibson B, Nahum-Shani I, Maxfield E, Locke A, Cornia R, Bradshaw R, Wirth J, Jaggers SJ, Lam CY, Wetter DW (2023). Increasing the reach of evidence-based interventions for weight management and diabetes prevention among Medicaid patients: study protocol for a pilot Sequential Multiple Assignment Randomised Trial. BMJ Open, 13(11), e075157. (Read full article)
  19. Wan YJ, Wright MC, McFarland MM, Dishman D, Nies MA, Rush A, Madaras-Kelly K, Jeppesen A, Del Fiol G (2023). Information displays for automated surveillance algorithms of in-hospital patient deterioration: a scoping review. J Am Med Inform Assoc. (Read full article)
  20. Stump TK, Wetter DW, Kuzmenko T, Orleans B, Kolp L, Wirth J, Del Fiol G, Chipman J, Haaland B, Kaphingst KA, Hersh AL, Wu YP (2023). Preliminary Reach of an Information Technology Approach to Support COVID-19 Testing in Schools. Pediatrics, 152(Suppl 1). (Read full article)
  21. Boyd AD, Gonzalez-Guarda R, Lawrence K, Patil CL, Ezenwa MO, OBrien EC, Paek H, Braciszewski JM, Adeyemi O, Cuthel AM, Darby JE, Zigler CK, Ho PM, Faurot KR, Staman KL, Leigh JW, Dailey DL, Cheville A, Del Fiol G, Knisely MR, Grudzen CR, Marsolo K, Richesson RL, Schlaeger JM (2023). Potential bias and lack of generalizability in electronic health record data: reflections on health equity from the National Institutes of Health Pragmatic Trials Collaboratory. J Am Med Inform Assoc. (Read full article)
  22. Boyd AD, Gonzalez-Guarda R, Lawrence K, Patil CL, Ezenwa MO, OBrien EC, Paek H, Braciszewski JM, Adeyemi O, Cuthel AM, Darby JE, Zigler CK, Ho PM, Faurot KR, Staman K, Leigh JW, Dailey DL, Cheville A, Del Fiol G, Knisely MR, Marsolo K, Richesson RL, Schlaeger JM (2023). Equity and bias in electronic health records data. Contemp Clin Trials, 107238. (Read full article)
  23. Gonzlez-Castro L, Chvez M, Duflot P, Bleret V, Martin AG, Zobel M, Nateqi J, Lin S, Pazos-Arias JJ, Del Fiol G, Lpez-Nores M (2023). Machine Learning Algorithms to Predict Breast Cancer Recurrence Using Structured and Unstructured Sources from Electronic Health Records. Cancers (Basel), 15(10). (Read full article)
  24. Kukhareva PV, Li H, Caverly TJ, Del Fiol G, Fagerlin A, Butler JM, Hess R, Zhang Y, Taft T, Flynn MC, Reddy C, Martin DK, Rodriguez-Loya S, Warner PB, Kawamoto K (2023). Implementation of Lung Cancer Screening in Primary Care and Pulmonary Clinics: Pragmatic Clinical Trial of Electronic Health Record-Integrated Everyday Shared Decision Making Tool and Clinician-Facing Prompts. Chest, 164(5), 1325-1338. (Read full article)
  25. Schlechter CR, Reese TJ, Wirth J, Gibson B, Kawamoto K, Siaperas T, Pruhs A, Pariera Dinkins C, Zhang Y, Friedrichs M, George S, Lam CY, Pierce JH, Borsato EP, Cornia RC, Stevens L, Martinez A, Bradshaw RL, Kaphingst KA, Hess R, Del Fiol G, Wetter DW (2023). Rapid-cycle designs to adapt interventions for COVID-19 in safety-net healthcare systems. Transl Behav Med, 13(6), 389-399. (Read full article)
  26. Benson R, Winterton C, Winn M, Krick B, Liu M, Abu-El-Rub N, Conway M, Del Fiol G, Gawron A, Hardikar S (2023). Leveraging Natural Language Processing to Extract Features of Colorectal Polyps From Pathology Reports for Epidemiologic Study. JCO Clin Cancer Inform, 7, e2200131. (Read full article)
  27. Liebermann E, Taber P, Vega AS, Daly BM, Goodman MS, Bradshaw R, Chan PA, Chavez-Yenter D, Hess R, Kessler C, Kohlmann W, Low S, Monahan R, Kawamoto K, Del Fiol G, Buys SS, Sigireddi M, Ginsburg O, Kaphingst KA (2022). Barriers to family history collection among Spanish-speaking primary care patients: a BRIDGE qualitative study. PEC Innov, 1. (Read full article)
  28. Lario R, Kawamoto K, Sottara D, Eilbeck K, Huff S, Del Fiol G, Soley R, Middleton B (2022). A method for structuring complex clinical knowledge and its representational formalisms to support composite knowledge interoperability in healthcare. J Biomed Inform, 137, 104251. (Read full article)
  29. Fritz JM, Del Fiol G, Gibson B, Wetter DW, Solis V, Bennett E, Thackeray A, Goode A, Lundberg K, Romero A, Ford I, Stevens L, Siaperas T, Morales J, Yack M, Greene T (2022). BeatPain Utah: study protocol for a pragmatic randomised trial examining telehealth strategies to provide non-pharmacologic pain care for persons with chronic low back pain receiving care in federally qualified health centers. BMJ Open, 12(11), e067732. (Read full article)
  30. Gomez Lumbreras A, Reese TJ, Del Fiol G, Tan MS, Butler JM, Hurwitz JT, Brown M, Kawamoto K, Thiess H, Wright M, Malone DC (2022). Shared Decision-Making for Drug-Drug Interactions: Formative Evaluation of an Anticoagulant Drug Interaction. JMIR Form Res, 6(10), e40018. (Read full article)
  31. Chavez-Yenter D, Goodman MS, Chen Y, Chu X, Bradshaw RL, Lorenz Chambers R, Chan PA, Daly BM, Flynn M, Gammon A, Hess R, Kessler C, Kohlmann WK, Mann DM, Monahan R, Peel S, Kawamoto K, Del Fiol G, Sigireddi M, Buys SS, Ginsburg O, Kaphingst KA (2022). Association of Disparities in Family History and Family Cancer History in the Electronic Health Record With Sex, Race, Hispanic or Latino Ethnicity, and Language Preference in 2 Large US Health Care Systems. JAMA Netw Open, 5(10), e2234574. (Read full article)
  32. Shi J, Morgan KL, Bradshaw RL, Jung SH, Kohlmann W, Kaphingst KA, Kawamoto K, Fiol GD (2022). Identifying Patients Who Meet Criteria for Genetic Testing of Hereditary Cancers Based on Structured and Unstructured Family Health History Data in the Electronic Health Record: Natural Language Processing Approach. JMIR Med Inform, 10(8), e37842. (Read full article)
  33. Wiley K, Findley L, Goldrich M, Rakhra-Burris TK, Stevens A, Williams P, Bult CJ, Chisholm R, Deverka P, Ginsburg GS, Green ED, Jarvik G, Mensah GA, Ramos E, Relling MV, Roden DM, Rowley R, Alterovitz G, Aronson S, Bastarache L, Cimino JJ, Crowgey EL, Del Fiol G, Freimuth RR, Hoffman MA, Jeff J, Johnson K, Kawamoto K, Madhavan S, Mendonca EA, Ohno-Machado L, Pratap S, Taylor CO, Ritchie MD, Walton N, Weng C, Zayas-Cabn T, Manolio TA, Williams MS (2022). A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. J Am Med Inform Assoc, 29, 1342-1349. (Read full article)
  34. Thiess H, Del Fiol G, Malone DC, Cornia R, Sibilla M, Rhodes B, Boyce RD, Kawamoto K, Reese T (2022). Coordinated use of Health Level 7 standards to support clinical decision support: Case study with shared decision making and drug-drug interactions. Int J Med Inform, 162, 104749. (Read full article)
  35. Bradshaw RL, Kawamoto K, Kaphingst KA, Kohlmann WK, Hess R, Flynn MC, Nanjo CJ, Warner PB, Shi J, Morgan K, Kimball K, Ranade-Kharkar P, Ginsburg O, Goodman M, Chambers R, Mann D, Narus SP, Gonzalez J, Loomis S, Chan P, Monahan R, Borsato EP, Shields DE, Martin DK, Kessler CM, Del Fiol G (2022). GARDE: a standards-based clinical decision support platform for identifying population health management cohorts. J Am Med Inform Assoc, 29(5), 928-936. (Read full article)
  36. Kukhareva PV, Caverly TJ, Li H, Katki HA, Cheung LC, Reese TJ, Del Fiol G, Hess R, Wetter DW, Zhang Y, Taft TY, Flynn MC, Kawamoto K (2022). Inaccuracies in electronic health records smoking data and a potential approach to address resulting underestimation in determining lung cancer screening eligibility. J Am Med Inform Assoc, 29(5), 779-788. (Read full article)
  37. Kukhareva PV, Weir C, Del Fiol G, Aarons GA, Taft TY, Schlechter CR, Reese TJ, Curran RL, Nanjo C, Borbolla D, Staes CJ, Morgan KL, Kramer HS, Stipelman CH, Shakib JH, Flynn MC, Kawamoto K (2022). Evaluation in Life Cycle of Information Technology (ELICIT) Framework: Supporting the Innovation Life Cycle from Business Case Assessment to Summative Evaluation. J Biomed Inform, 127, 104014. (Read full article)
  38. Reese T, Wright A, Liu S, Boyce R, Romero A, Del Fiol G, Kawamoto K, Malone D (2022). Improving the specificity of drug-drug interaction alerts: Can it be done? Am J Health Syst Pharm, 79, 1086-1095. (Read full article)
  39. Wan YJ, Del Fiol G, McFarland MM, Wright MC (2022). User interface approaches implemented with automated patient deterioration surveillance tools: protocol for a scoping review. BMJ Open, 12(1), e055525. (Read full article)
  40. Liu S, Kawamoto K, Del Fiol G, Weir C, Malone DC, Reese TJ, Morgan K, ElHalta D, Abdelrahman S (2022). The potential for leveraging machine learning to filter medication alerts. J Am Med Inform Assoc, 29, 891-899. (Read full article)
  41. Gonzlez-Castro L, Cal-Gonzlez VM, Del Fiol G, Lpez-Nores M (2021). CASIDE: A data model for interoperable cancer survivorship information based on FHIR. J Biomed Inform, 124, 103953. (Read full article)
  42. Khalifa A, Mason CC, Garvin JH, Williams MS, Del Fiol G, Jackson BR, Bleyl SB, Alterovitz G, Huff SM (2021). Interoperable genetic lab test reports: mapping key data elements to HL7 FHIR specifications and professional reporting guidelines. J Am Med Inform Assoc, 28(12), 2617-2625. (Read full article)
  43. Richesson RL, Marsolo KS, Douthit BJ, Staman K, Ho PM, Dailey D, Boyd AD, McTigue KM, Ezenwa MO, Schlaeger JM, Patil CL, Faurot KR, Tuzzio L, Larson EB, OBrien EC, Zigler CK, Lakin JR, Pressman AR, Braciszewski JM, Grudzen C, Fiol GD (2021). Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory. J Am Med Inform Assoc, 28(12), 2626-2640. (Read full article)
  44. Chavez-Yenter D, Kimball KE, Kohlmann W, Lorenz Chambers R, Bradshaw RL, Espinel WF, Flynn M, Gammon A, Goldberg E, Hagerty KJ, Hess R, Kessler C, Monahan R, Temares D, Tobik K, Mann DM, Kawamoto K, Del Fiol G, Buys SS, Ginsburg O, Kaphingst KA (2021). Patient Interactions With an Automated Conversational Agent Delivering Pretest Genetics Education: Descriptive Study. J Med Internet Res, 23(11), e29447. (Read full article)
  45. Khalifa A, Mason CC, Garvin JH, Williams MS, Del Fiol G, Jackson BR, Bleyl SB, Huff SM (2021). A qualitative study of prevalent laboratory information systems and data communication patterns for genetic test reporting. Genet Med, 23(11), 2171-2177. (Read full article)
  46. Khalifa A, Mason CC, Garvin JH, Williams MS, Del Fiol G, Jackson BR, Bleyl SB, Huff SM (2021). A qualitative investigation of biomedical informatics interoperability standards for genetic test reporting: benefits, challenges, and motivations from the testing laboratory's perspective. Genet Med, 23(11), 2178-2185. (Read full article)
  47. Reese TJ, Del Fiol G, Morgan K, Hurwitz JT, Kawamoto K, Gomez-Lumbreras A, Brown ML, Thiess H, Vazquez SR, Nelson SD, Boyce R, Malone D (2021). A Shared Decision-making Tool for Drug Interactions Between Warfarin and Nonsteroidal Anti-inflammatory Drugs: Design and Usability Study. JMIR Hum Factors, 8(4), e28618. (Read full article)
  48. Schlechter CR, Del Fiol G, Lam CY, Fernandez ME, Greene T, Yack M, Schulthies S, Nelson M, Bohner C, Pruhs A, Siaperas T, Kawamoto K, Gibson B, Nahum-Shani I, Walker TJ, Wetter DW (2021). Application of community - engaged dissemination and implementation science to improve health equity. Prev Med Rep, 24, 101620. (Read full article)
  49. Schlechter CR, Del Fiol G, Lam CY, Fernandez ME, Greene T, Yack M, Schulthies S, Nelson M, Bohner C, Pruhs A, Siaperas T, Kawamoto K, Gibson B, Nahum-Shani I, Walker TJ, Wetter DW (2021). Application of community - engaged dissemination and implementation science to improve health equity. Prev Med Rep, 24, 101620.
  50. Liu S, Reese TJ, Kawamoto K, Del Fiol G, Weir C (2021). A theory-based meta-regression of factors influencing clinical decision support adoption and implementation. J Am Med Inform Assoc, 28(11), 2514-2522. (Read full article)
  51. Karhade AV, Schwab JH, Del Fiol G, Kawamoto K (2020). SMART on FHIR in spine: integrating clinical prediction models into electronic health records for precision medicine at the point of care. Spine J, 21(10), 1649-1651. (Read full article)
  52. Reese TJ, Segall N, Del Fiol G, Tonna JE, Kawamoto K, Weir C, Wright MC (2020). Iterative heuristic design of temporal graphic displays with clinical domain experts. J Clin Monit Comput, 35(5), 1119-1131. (Read full article)
  53. Reese TJ, Schlechter CR, Kramer H, Kukhareva P, Weir CR, Del Fiol G, Caverly T, Hess R, Flynn MC, Taft T, Kawamoto K (2021). Implementing lung cancer screening in primary care: needs assessment and implementation strategy design. Transl Behav Med, 12, 187-197. (Read full article)
  54. Kepka D, Christini K, McGough E, Wagner A, Del Fiol G, Gibson B, Ayres S, Brandt HM, Mann S, Petrik AF, Coronado GD (2021). Successful Multi-Level HPV Vaccination Intervention at a Rural Healthcare Center in the Era of COVID-19. Front Digit Health, 3, 719138. (Read full article)
  55. Taber P, Staes CJ, Phengphoo S, Rocha E, Lam A, Del Fiol G, Maviglia SM, Rocha RA (2021). Developing a sampling method and preliminary taxonomy for classifying COVID-19 public health guidance for healthcare organizations and the general public. J Biomed Inform, 120, 103852. (Read full article)
  56. Taber P, Radloff C, Del Fiol G, Staes C, Kawamoto K (2021). New Standards for Clinical Decision Support: A Survey of The State of Implementation. Yearb Med Inform, 30(1), 159-171. (Read full article)
  57. Kawamoto K, Kukhareva PV, Weir C, Flynn MC, Nanjo CJ, Martin DK, Warner PB, Shields DE, Rodriguez-Loya S, Bradshaw RL, Cornia RC, Reese TJ, Kramer HS, Taft T, Curran RL, Morgan KL, Borbolla D, Hightower M, Turnbull WJ, Strong MB, Chapman WW, Gregory T, Stipelman CH, Shakib JH, Hess R, Boltax JP, Habboushe JP, Sakaguchi F, Turner KM, Narus SP, Tarumi S, Takeuchi W, Ban H, Wetter DW, Lam C, Caverly TJ, Fagerlin A, Norlin C, Malone DC, Kaphingst KA, Kohlmann WK, Brooke BS, Del Fiol G (2021). Establishing a multidisciplinary initiative for interoperable electronic health record innovations at an academic medical center. JAMIA Open, 4(3), ooab041. (Read full article)
  58. Strasberg HR, Rhodes B, Del Fiol G, Jenders RA, Haug PJ, Kawamoto K (2021). Contemporary clinical decision support standards using Health Level Seven International Fast Healthcare Interoperability Resources. J Am Med Inform Assoc, 28(8), 1796-1806. (Read full article)
  59. Morid MA, Lau M, Del Fiol G (2021). Predictive analytics for step-up therapy: Supervised or semi-supervised learning? J Biomed Inform, 119, 103842. (Read full article)
  60. Douthit BJ, Staes CJ, Del Fiol G, Richesson RL (2021). A thematic analysis to examine the feasibility of EHR-based clinical decision support for implementing Choosing Wisely ® guidelines. JAMIA Open, 4(2), ooab031. (Read full article)
  61. Kaphingst KA, Kohlmann W, Chambers RL, Goodman MS, Bradshaw R, Chan PA, Chavez-Yenter D, Colonna SV, Espinel WF, Everett JN, Gammon A, Goldberg ER, Gonzalez J, Hagerty KJ, Hess R, Kehoe K, Kessler C, Kimball KE, Loomis S, Martinez TR, Monahan R, Schiffman JD, Temares D, Tobik K, Wetter DW, Mann DM, Kawamoto K, Del Fiol G, Buys SS, Ginsburg O, BRIDGE research team (2021). Comparing models of delivery for cancer genetics services among patients receiving primary care who meet criteria for genetic evaluation in two healthcare systems: BRIDGE randomized controlled trial. BMC Health Serv Res, 21(1), 542. (Read full article)
  62. Douthit BJ, Del Fiol G, Staes CJ, Docherty SL, Richesson RL (2021). A Conceptual Framework of Data Readiness: The Contextual Intersection of Quality, Availability, Interoperability, and Provenance. Appl Clin Inform, 12(3), 675-685. (Read full article)
  63. Tiase VL, Wawrzynski SE, Sward KA, Del Fiol G, Staes C, Weir C, Cummins MR (2021). Provider Preferences for Patient-Generated Health Data Displays in Pediatric Asthma: A Participatory Design Approach. Appl Clin Inform, 12(3), 664-674. (Read full article)
  64. Weir CR, Taber P, Taft T, Reese TJ, Jones B, Del Fiol G (2020). Feeling and thinking: can theories of human motivation explain how EHR design impacts clinician burnout? J Am Med Inform Assoc, 28(5), 1042-1046. (Read full article)
  65. Gibson B, Kramer H, Weir C, Del Fiol, G, Borbolla D, Schlechter C, Lam C, Nelson M, Bohner C, Schulthies S, Sieperas T, Pruhs A, Nahum-Shani I, Fernandez ME, Wetter D (2021). Workflow analysis for design of an electronic health record-based tobacco cessation intervention in community health centers. JAMIA Open.
  66. Oosterhoff JH, Thio QC, Groot OQ, Bongers ME, Ghaednia H, Karhade AV, Del Fiol G, Kawamoto K (2021). Integration of automated predictive analytics into electronic health records: can spine surgery applications lead the way using SMART on FHIR and CDS Hooks? Semin Spine Surg, 100870.
  67. Liu S, Reese TJ, Kawamoto K, Del Fiol G, Weir C (2021). A systematic review of theoretical constructs in CDS literature. BMC Med Inform Decis Mak, 21(1), 102. (Read full article)
  68. Rasmussen LV, Connolly JJ, Del Fiol G, Freimuth RR, Pet DB, Peterson JF, Shirts BH, Starren JB, Williams MS, Walton N, Taylor CO (2021). Infobuttons for Genomic Medicine: Requirements and Barriers. Appl Clin Inform, 12(2), 383-390. (Read full article)
  69. Gibson B, Kramer H, Weir C, Fiol G, Borbolla D, Schlechter CR, Lam C, Nelson M, Bohner C, Schulthies S, Sieperas T, Pruhs A, Nahum-Shani I, Fernandez ME, Wetter DW (2021). Workflow analysis for design of an electronic health record-based tobacco cessation intervention in community health centers. JAMIA Open, 4(3), ooaa070. (Read full article)
  70. Tiase VL, Sward KA, Del Fiol G, Staes C, Weir C, Cummins MR (2021). Patient-Generated Health Data in Pediatric Asthma: Exploratory Study of Providers' Information Needs. JMIR Pediatr Parent, 4(1), e25413. (Read full article)
  71. Reese TJ, Schlechter CR, Potter LN, Kawamoto K, Del Fiol G, Lam CY, Wetter DW (2021). Evaluation of Revised US Preventive Services Task Force Lung Cancer Screening Guideline Among Women and Racial/Ethnic Minority Populations. JAMA Netw Open, 4(1), e2033769. (Read full article)
  72. Morid MA, Borjali A, Del Fiol G (2020). A scoping review of transfer learning research on medical image analysis using ImageNet. Comput Biol Med, 128, 104115. (Read full article)
  73. Tiase VL, Hull W, McFarland MM, Sward KA, Del Fiol G, Staes C, Weir C, Cummins MR (2020). Patient-generated health data and electronic health record integration: a scoping review. JAMIA Open, 3(4), 619-627. (Read full article)
  74. Taber P, Ghani P, Schiffman JD, Kohlmann W, Hess R, Chidambaram V, Kawamoto K, Waller RG, Borbolla D, Del Fiol G, Weir C (2020). Physicians' strategies for using family history data: having the data is not the same as using the data. JAMIA Open, 3(3), 378-385. (Read full article)
  75. Reese TJ, Del Fiol G, Tonna JE, Kawamoto K, Segall N, Weir C, Macpherson BC, Kukhareva P, Wright MC (2020). Impact of integrated graphical display on expert and novice diagnostic performance in critical care. J Am Med Inform Assoc, 27(8), 1287-1292. (Read full article)
  76. Cummins MR, Del Fiol G, Crouch BI, Ranade-Kharkar P, Khalifa A, Iskander A, Mann D, Hoffman M, Thornton S, Allen TL, Bennett H (2019). Enabling health information exchange at a US Poison Control Center. J Am Med Inform Assoc, 27(7), 1000-1006. (Read full article)
  77. Penning ML, Blach C, Walden A, Wang P, Donovan KM, Garza MY, Wang Z, Frund J, Syed S, Syed M, Del Fiol G, Newby LK, Pieper C, Zozus M (2020). Near Real Time EHR Data Utilization in a Clinical Study. Stud Health Technol Inform, 270, 337-341. (Read full article)
  78. Haynes RB, Del Fiol G, Michelson M, Iorio A (2020). Context and Approach in Reporting Evaluations of Electronic Health Record-Based Implementation Projects. Ann Intern Med, 172(11 Suppl), S73-S78. (Read full article)
  79. Hanauer DA, Barnholtz-Sloan JS, Beno MF, Del Fiol G, Durbin EB, Gologorskaya O, Harris D, Harnett B, Kawamoto K, May B, Meeks E, Pfaff E, Weiss J, Zheng K (2020). Electronic Medical Record Search Engine (EMERSE): An Information Retrieval Tool for Supporting Cancer Research. JCO Clin Cancer Inform, 4, 454-463. (Read full article)
  80. Richesson RL, Staes CJ, Douthit BJ, Thoureen T, Hatch DJ, Kawamoto K, Del Fiol G (2019). Measuring implementation feasibility of clinical decision support alerts for clinical practice recommendations. J Am Med Inform Assoc, 27(4), 514-521. (Read full article)
  81. Morid MA, Sheng ORL, Del Fiol G, Facelli JC, Bray BE, Abdelrahman S (2020). Temporal Pattern Detection to Predict Adverse Events in Critical Care: Case Study With Acute Kidney Injury. JMIR Med Inform, 8(3), e14272. (Read full article)
  82. Fernandez ME, Schlechter CR, Del Fiol G, Gibson B, Kawamoto K, Siaperas T, Pruhs A, Greene T, Nahum-Shani I, Schulthies S, Nelson M, Bohner C, Kramer H, Borbolla D, Austin S, Weir C, Walker TW, Lam CY, Wetter DW (2020). QuitSMART Utah: an implementation study protocol for a cluster-randomized, multi-level Sequential Multiple Assignment Randomized Trial to increase Reach and Impact of tobacco cessation treatment in Community Health Centers. Implement Sci, 15(1), 9. (Read full article)
  83. Del Fiol G, Kohlmann W, Bradshaw RL, Weir CR, Flynn M, Hess R, Schiffman JD, Nanjo C, Kawamoto K (2020). Standards-Based Clinical Decision Support Platform to Manage Patients Who Meet Guideline-Based Criteria for Genetic Evaluation of Familial Cancer. JCO Clin Cancer Inform, 4, 1-9. (Read full article)
  84. Tiase VL, Hull W, McFarland MM, Sward KA, Del Fiol G, Staes C, Weir C, Cummins MR (2019). Patient-generated health data and electronic health record integration: protocol for a scoping review. BMJ Open, 9(12), e033073. (Read full article)
  85. Brooke BS, Beckstrom J, Slager SL, Weir CR, Del Fiol G (2019). Discordance in Information Exchange Between Providers During Care Transitions for Surgical Patients. J Surg Res, 244, 174-180. (Read full article)
  86. Colicchio TK, Del Fiol G, Cimino JJ (2019). Health information technology as a learning health system: Call for a national monitoring system. Learn Health Syst, 4(1), e10207. (Read full article)
  87. Kawamoto K, Kukhareva P, Shakib JH, Kramer H, Rodriguez S, Warner PB, Shields D, Weir C, Del Fiol G, Taft T, Stipelman CH (2019). Association of an Electronic Health Record Add-on App for Neonatal Bilirubin Management With Physician Efficiency and Care Quality. JAMA Netw Open, 2(11), e1915343. (Read full article)
  88. Williams MS, Taylor CO, Walton NA, Goehringer SR, Aronson S, Freimuth RR, Rasmussen LV, Hall ES, Prows CA, Chung WK, Fedotov A, Nestor J, Weng C, Rowley RK, Wiesner GL, Jarvik GP, Del Fiol G (2019). Genomic Information for Clinicians in the Electronic Health Record: Lessons Learned From the Clinical Genome Resource Project and the Electronic Medical Records and Genomics Network. Front Genet, 10, 1059. (Read full article)
  89. Aakre CA, Maggio LA, Fiol GD, Cook DA (2019). Barriers and facilitators to clinical information seeking: a systematic review. J Am Med Inform Assoc, 26(10), 1129-1140. (Read full article)
  90. Wright MC, Borbolla D, Waller RG, Del Fiol G, Reese T, Nesbitt P, Segall N (2019). Critical care information display approaches and design frameworks: A systematic review and meta-analysis. J Biomed Inform X, 3. (Read full article)
  91. Maggio LA, Aakre CA, Del Fiol G, Shellum J, Cook DA (2019). Impact of Clinicians' Use of Electronic Knowledge Resources on Clinical and Learning Outcomes: Systematic Review and Meta-Analysis. J Med Internet Res, 21(7), e13315. (Read full article)
  92. Colicchio TK, Cimino JJ, Del Fiol G (2019). Unintended Consequences of Nationwide Electronic Health Record Adoption: Challenges and Opportunities in the Post-Meaningful Use Era. J Med Internet Res, 21(6), e13313. (Read full article)
  93. Colicchio TK, Borbolla D, Colicchio VD, Scammon DL, Del Fiol G, Facelli JC, Bowes WA 3rd, Narus SP (2019). Looking Behind the Curtain: Identifying Factors Contributing to Changes on Care Outcomes During a Large Commercial EHR Implementation. EGEMS (Wash DC), 7(1), 21. (Read full article)
  94. Mowery DL, Kawamoto K, Bradshaw R, Kohlmann W, Schiffman JD, Weir C, Borbolla D, Chapman WW, Del Fiol G (2019). Determining Onset for Familial Breast and Colorectal Cancer from Family History Comments in the Electronic Health Record. AMIA Jt Summits Transl Sci Proc, 2019, 173-181. (Read full article)
  95. Wright MC, Borbolla D, Waller RG, Del Fiol G, Reese T, Nesbitt P, Segall N (2019). Critical care information display approaches and design frameworks: A systematic review and meta-analysis. J Biomed Inform, 100S, 100041. (Read full article)
  96. Colicchio TK, Del Fiol G, Scammon DL, Facelli JC, Bowes WA 3rd, Narus SP (2018). Comprehensive methodology to monitor longitudinal change patterns during EHR implementations: a case study at a large health care delivery network. J Biomed Inform, 83, 40-53. (Read full article)
  97. Bian J, Weir C, Unni P, Borbolla D, Reese T, Wan YJ, Del Fiol G (2018). Interactive Visual Displays for Interpreting the Results of Clinical Trials: Formative Evaluation With Case Vignettes. J Med Internet Res, 20(6), e10507. (Read full article)
  98. Del Fiol G, Michelson M, Iorio A, Cotoi C, Haynes RB (2018). A Deep Learning Method to Automatically Identify Reports of Scientifically Rigorous Clinical Research from the Biomedical Literature: Comparative Analytic Study. J Med Internet Res, 20(6), e10281. (Read full article)
  99. Ranade-Kharkar P, Weir C, Norlin C, Collins SA, Scarton LA, Baker GB, Borbolla D, Taliercio V, Del Fiol G (2017). Information needs of physicians, care coordinators, and families to support care coordination of children and youth with special health care needs (CYSHCN). J Am Med Inform Assoc, 24(5), 933-941. (Read full article)
  100. Cook DA, Teixeira MT, Heale BS, Cimino JJ, Del Fiol G (2017). Context-sensitive decision support (infobuttons) in electronic health records: a systematic review. J Am Med Inform Assoc, 24(2), 460-468. (Read full article)
  101. Morid MA, Fiszman M, Raja K, Jonnalagadda SR, Del Fiol G (2016). Classification of clinically useful sentences in clinical evidence resources. J Biomed Inform, 60, 14-22. (Read full article)
  102. Del Fiol G, Mostafa J, Pu D, Medlin R, Slager S, Jonnalagadda SR, Weir CR (2016). Formative evaluation of a patient-specific clinical knowledge summarization tool. Int J Med Inform, 86, 126-34. (Read full article)
  103. Del Fiol G, Crouch BI, Cummins MR (2015). Data standards to support health information exchange between poison control centers and emergency departments. J Am Med Inform Assoc, 22(3), 519-28. (Read full article)
  104. Mishra R, Bian J, Fiszman M, Weir CR, Jonnalagadda S, Mostafa J, Del Fiol G (2014). Text summarization in the biomedical domain: a systematic review of recent research. J Biomed Inform, 52, 457-67. (Read full article)
  105. Del Fiol G, Weber AI, Brunker CP, Weir CR (2014). Clinical questions raised by providers in the care of older adults: a prospective observational study. BMJ Open, 4(7), e005315. (Read full article)
  106. Del Fiol G, Workman TE, Gorman PN (2014). Clinical questions raised by clinicians at the point of care: a systematic review. JAMA Intern Med, 174(5), 710-8. (Read full article)
  107. Jonnalagadda SR, Del Fiol G, Medlin R, Weir C, Fiszman M, Mostafa J, Liu H (2013). Automatically extracting sentences from Medline citations to support clinicians' information needs. J Am Med Inform Assoc, 20(5), 995-1000. (Read full article)
  108. Strasberg HR, Del Fiol G, Cimino JJ (2013). Terminology challenges implementing the HL7 context-aware knowledge retrieval ('Infobutton') standard. J Am Med Inform Assoc, 20(2), 218-23. (Read full article)
  109. Del Fiol G, Curtis C, Cimino JJ, Iskander A, Kalluri AS, Jing X, Hulse NC, Long J, Overby CL, Schardt C, Douglas DM (2013). Disseminating context-specific access to online knowledge resources within electronic health record systems. Stud Health Technol Inform, 192, 672-6. (Read full article)
  110. Del Fiol G, Huser V, Strasberg HR, Maviglia SM, Curtis C, Cimino JJ (2012). Implementations of the HL7 Context-Aware Knowledge Retrieval ("Infobutton") Standard: challenges, strengths, limitations, and uptake. J Biomed Inform, 45(4), 726-35. (Read full article)
  111. Kawamoto K, Del Fiol G, Lobach DF, Jenders RA (2010). Standards for scalable clinical decision support: need, current and emerging standards, gaps, and proposal for progress. Open Med Inform J, 4, 235-44. (Read full article)
  112. Kawamoto K, Del Fiol G, Orton C, Lobach DF (2010). System-agnostic clinical decision support services: benefits and challenges for scalable decision support. Open Med Inform J, 4, 245-54. (Read full article)
  113. Del Fiol G, Haug PJ, Cimino JJ, Narus SP, Norlin C, Mitchell JA (2008). Effectiveness of topic-specific infobuttons: a randomized controlled trial. J Am Med Inform Assoc, 15(6), 752-9. (Read full article)
  114. Del Fiol G, Haug PJ (2008). Infobuttons and classification models: a method for the automatic selection of on-line information resources to fulfill clinicians' information needs. J Biomed Inform, 41(4), 655-66. (Read full article)
  115. Del Fiol G, Haug PJ (2007). Use of classification models based on usage data for the selection of infobutton resources. AMIA Annu Symp Proc, 171-5. (Read full article)
  116. Del Fiol G, Rocha RA, Clayton PD (2007). Infobuttons at Intermountain Healthcare: utilization and infrastructure. AMIA Annu Symp Proc, 180-4. (Read full article)
  117. Del Fiol G, Rocha RA, Bradshaw RL, Hulse NC, Roemer LK (2005). An XML model that enables the development of complex order sets by clinical experts. IEEE Trans Inf Technol Biomed, 9(2), 216-28. (Read full article)
  118. Hulse NC, Del Fiol G, Rocha RA (2006). Development and validation of XML-based calculations within order sets. AMIA Annu Symp Proc, 360-4. (Read full article)
  119. Del Fiol G, Rocha RA, Washburn J, Rhodes J, Hulse N, Bradshaw RL, Roemer LK (2007). "On-demand" access to a multi-purpose collection of best practice standards. Conf Proc IEEE Eng Med Biol Soc, 2004, 3342-5. (Read full article)
  120. Hulse NC, Rocha RA, Del Fiol G, Bradshaw RL, Hanna TP, Roemer LK (2007). The knowledge authoring tool: an XML-based knowledge acquisition environment. Conf Proc IEEE Eng Med Biol Soc, 2004, 3350-3. (Read full article)

Review

  1. Roberts MC, Holt KE, Del Fiol G, Baccarelli AA, Allen CG (2024). Precision public health in the era of genomics and big data. [Review]. Nat Med. (Read full article)
  2. Taber P, Armin JS, Orozco G, Del Fiol G, Erdrich J, Kawamoto K, Israni ST (2023). Artificial Intelligence and Cancer Control: Toward Prioritizing Justice, Equity, Diversity, and Inclusion (JEDI) in Emerging Decision Support Technologies. [Review]. Curr Oncol Rep, 25(5), 387-424. (Read full article)

Book

  1. Robert A Greenes, Guilherme Del Fiol (2023). Clinical Decision Support and Beyond: Progress and Opportunities in Knowledge-Enhanced Health and Healthcare (3rd). Elsevier Science.

Conference Proceedings

  1. Borbolla DA, Del Fiol G, Norlin C, Taft TE, Cornia R, Warner P, Iskander A, Kramer H, Weir C, Kawamoto K, Shields D (2021). Design and Development of an Electronic Health Record Add-on App to Support the Care of Children and Youth with Special Health Care Needs. Pediatrics, American Academy of Pediatrics, 147(3), 8-9.

Editorial

  1. Kawamoto K, Finkelstein J, Del Fiol G (2023). Implementing Machine Learning in the Electronic Health Record: Checklist of Essential Considerations. Mayo Clin Proc, 98(3), 366-369. (Read full article)
  2. Humphreys BL, Del Fiol G, Xu H (2020). The UMLS knowledge sources at 30: indispensable to current research and applications in biomedical informatics. J Am Med Inform Assoc, 27(10), 1499-1501. (Read full article)

Other

  1. Shi J, Morgan KL, Bradshaw RL, Jung SH, Kohlmann W, Kaphingst KA, Kawamoto K, Fiol GD (2022). Correction: Identifying Patients Who Meet Criteria for Genetic Testing of Hereditary Cancers Based on Structured and Unstructured Family Health History Data in the Electronic Health Record: Natural Language Processing Approach. JMIR Med Inform (10(9), pp. e42533). Canada. (Read full article)

Report

  1. Hall LK, Del Fiol G, Lenert L (09/18/2014). Using Health Information Technology to Support Shared Decision Making.. Washington, DC: Institute of Medicine.

News & Podcasts

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