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Anthony J. Donato, Ph.D., M.S.

Languages spoken: English

Academic Information

Departments: Internal Medicine - Professor, Biochemistry - Adjunct Professor, Nutrition and Integrative Physiology - Adjunct Professor

Divisions: Geriatrics

Academic Office Information

tony.donato@hsc.utah.edu

(801) 584-2522

VA - Building #2
VA Salt Lake City GRECC
500 S Foothill Dr, Room:
Salt Lake City, UT 84148

My primary research focus is vascular aging, in particular the cellular, molecular and tissue specific events that induce reductions in muscle blood flow during exercise, impair arterial endothelial function and stiffen large elastic arteries in older rodents/adults. These vascular phenotypes contribute to the age related decline in functional capacity and the development of cardiovascular disease, and can be ameliorated by lifestyle interventions such as habitual exercise and caloric restriction. My secondary focus, is to elucidate the cellular pathways which confer the vaso-protective effects of these lifestyle interventions and try to activate these pathways pharmacologically to see if this will confer some of the same benefits. I have used human, rodent, and cell models to address these questions and utilized a wide range of contemporary translational experimental techniques from microRNA gene expression to ultrasonography to investigate the aforementioned interests.

Education History

Postdoctoral Fellowship University of Colorado, Department of Integrative Physiology
Integrative Physiology of Aging Laboratory, Dr. Doug Seals
Postdoctoral Fellow
Postdoctoral Fellowship University of California at San Diego, Department of Medicine, Dr. Russell Richardson
Postdoctoral Fellow
Doctoral Training Texas A&M University
Kinesiology
Ph.D.
Graduate Training University of Colorado, Boulder
Kinesiology and Applied Physiology
M.S.
Undergraduate University of Colorado, Boulder
Kinesiology
B.A.

Global Impact

Presentations

Description Country
"Telomere uncapping causes cellular senescence and inflammation in arteries: implications for arterial aging and hypertension” First International Medical Science Summit of the Tongji Hospital Wuhan, China China