Laura J. Martins

Laura J. Martins, PhD

Languages spoken: English

Academic Information

Departments Primary - Pathology

Academic Office Information

laura.martins@path.utah.edu

Education History

Graduate Training University of Utah
 PhD
Colorado State University
 BS

Selected Publications

Journal Article

  1. Lim AL, Moos P, Pond CD, Larson EC, Martins LJ, Szaniawski MA, Planelles V, Barrows LR (2022). HIV-1 provirus transcription and translation in macrophages differs from pre-integrated cDNA complexes and requires E2F transcriptional programs. Virulence, 13(1), 386-413.
  2. Martins LJ, Szaniawski MA, Williams ESCP, Coiras M, Hanley TM, Planelles V (2022). HIV-1 Accessory Proteins Impart a Modest Interferon Response and Upregulate Cell Cycle-Related Genes in Macrophages. Pathogens, 11(2).
  3. Larragoite ET, Nell RA, Martins LJ, Barrows LR, Planelles V, Spivak AM (2021). Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation. Biochem Pharmacol, 195, 114844.
  4. Zheng Y, Schubert HL, Singh PK, Martins LJ, Engelman AN, DOrso I, Hill CP, Planelles V (2021). Cleavage and Polyadenylation Specificity Factor 6 Is Required for Efficient HIV-1 Latency Reversal. mBio, 12(3), e0109821.
  5. Hotter D, Bosso M, Jnsson KL, Krapp C, Strzel CM, Das A, Littwitz-Salomon E, Berkhout B, Russ A, Wittmann S, Gramberg T, Zheng Y, Martins LJ, Planelles V, Jakobsen MR, Hahn BH, Dittmer U, Sauter D, Kirchhoff F (2019). IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation. Cell Host Microbe, 25(6), 858-872.e13.
  6. Spivak AM, Nell RA, Petersen M, Martins L, Sebahar P, Looper RE, Planelles V (2018). Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal. Antimicrob Agents Chemother, 62(11).
  7. Macedo AB, Resop RS, Martins LJ, Szaniawski MA, Sorensen ES, Spivak AM, Nixon DF, Jones RB, Planelles V, Bosque A (2018). Influence of Biological Sex, Age, and HIV Status in an In Vitro Primary Cell Model of HIV Latency Using a CXCR4 Tropic Virus. AIDS Res Hum Retroviruses, 34(9), 769-777.
  8. Larson EC, Novis CL, Martins LJ, Macedo AB, Kimball KE, Bosque A, Planelles V, Barrows LR (2017). Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitro. PLoS One, 12(9), e0185162.
  9. Bosque A, Nilson KA, Macedo AB, Spivak AM, Archin NM, Van Wagoner RM, Martins LJ, Novis CL, Szaniawski MA, Ireland CM, Margolis DM, Price DH, Planelles V (2016). Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation. Cell Rep, 18(5), 1324-1334.
  10. Spivak AM, Larragoite ET, Coletti ML, Macedo AB, Martins LJ, Bosque A, Planelles V (2016). Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo. Retrovirology, 13(1), 88.
  11. Larson EC, Pond CD, Szaniawski MA, Martins LJ, Planelles V, Barrows LR (2016). Macrophage Cell Coinfected with HIV-1 and H37Ra. AIDS Res Hum Retroviruses, 32(12), 1171-1172.
  12. White CH, Moesker B, Beliakova-Bethell N, Martins LJ, Spina CA, Margolis DM, Richman DD, Planelles V, Bosque A, Woelk CH (2016). Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model. PLoS Pathog, 12(11), e1006026.
  13. Martins LJ, Bonczkowski P, Spivak AM, De Spiegelaere W, Novis CL, DePaula-Silva AB, Malatinkova E, Trypsteen W, Bosque A, Vanderkerckhove L, Planelles V (2015). Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus. AIDS Res Hum Retroviruses, 32(2), 187-93.
  14. Spivak AM, Bosque A, Balch AH, Smyth D, Martins L, Planelles V (2015). Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients. Antimicrob Agents Chemother, 59(10), 5984-91.