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Michael Karsy, MD, PHD

Languages spoken: English

Academic Information

Departments: Neurosurgery - Assistant Professor

Academic Office Information

Michael.Karsy@hsc.utah.edu

Dr. Karsy is a skull base neurosurgeon who treats tumor and vascular pathologies through minimally-invasive endoscopic and traditional, open microsurgical approaches. He works with a large multi-disciplinary team that consists of neuroradiologists, neuropathologists, neuroophthalmologists, neuroendocrinologists, and specialized otolaryngology (ENT) cancer surgeons to ensure the best treatment outcomes. Dr. Karsy has experience with radiosurgery in a variety of complex cranial pathologies. His research interests are in improving health care outcomes, novel surgical approaches, and better molecular characterization of tumors.

Education History

Fellowship Thomas Jefferson University
Minimally Invasive & Open Skull Base Surgery
Fellow
Chief Resident University of Utah School of Medicine
Neurosurgery
Chief Resident
Fellowship University of Utah School of Medicine
Enfolded Fellowship: Complex & Minimally Invasive Spinal Neurosurgery
Fellow
Graduate Training University of Utah
Bioengineering
M.S.
Residency University of Utah School of Medicine
Neurosurgery
Resident
Professional Medical New York Medical College
Medicine
M.D., Ph.D.
Undergraduate University of California, Los Angeles
Neuroscience
B.S.

Selected Publications

  1. Cutler CB, Henson JC, Alt J, Karsy M (2022). How I Do It: Endonasal transethmoidal, transcribriform approach for resection of giant olfactory groove meningioma. Acta Neurochir (Wien).
  2. Piper K, Yu S, Taghvaei M, Fernandez C, Mouchtouris N, Smit RD, Yudkoff C, Collopy S, Reyes M, Lavergne P, Karsy M, Prashant GN, Shi W, Evans J (2022). Radiation of meningioma dural tail may not improve tumor control rates. Front Surg, 9, 908745.
  3. Felix B, Kalatar SB, Moatz B, Hofstetter C, Karsy M, Parr R, Gibby W (2022). Augmented Reality Spine Surgery Navigation: Increasing Pedicle Screw Insertion Accuracy for Both Open and Minimally Invasive Spine Surgeries. Spine (Phila Pa 1976), 47(12), 865-872.
  4. Batchu S, Patel K, Yu S, Mohamed AT, Karsy M (2022). Single cell transcriptomics reveals unique metabolic profiles of ependymoma subgroups. Gene, 820, 146278.
  5. Reyes M, Taghvaei M, Yu S, Sathe A, Collopy S, Prashant GN, Evans JJ, Karsy M (2021). Targeted Therapy in the Management of Modern Craniopharyngiomas. [Review]. Front Biosci (Landmark Ed), 27(4), 136.
  6. Crabb BT, Hamrick F, Campbell JM, Vignolles-Jeong J, Magill ST, Prevedello DM, Carrau RL, Otto BA, Hardesty DA, Couldwell WT, Karsy M (2022). Machine Learning-Based Analysis and Prediction of Unplanned 30-Day Readmissions After Pituitary Adenoma Resection: A Multi-Institutional Retrospective Study With External Validation. Neurosurgery, 91, 263-271.
  7. Henson JC, Gill A, Alt J, Karsy MJ (2022). How I do it: endonasal transcribriform approach for resection of esthesioneuroblastoma. Acta Neurochir (Wien), 164, 1949-1952.
  8. Mouchtouris N, Smit RD, Piper K, Prashant G, Evans JJ, Karsy M (2021). A review of multiomics platforms in pituitary adenoma pathogenesis. [Review]. Front Biosci (Landmark Ed), 27(3), 77.
  9. Yu S, Taghvaei M, Reyes M, Piper K, Collopy S, Gaughan JP, Prashant GN, Karsy M, Evans JJ (2022). Delayed symptomatic hyponatremia in transsphenoidal surgery: Systematic review and meta-analysis of its incidence and prevention with water restriction. [Review]. Clin Neurol Neurosurg, 214, 107166.
  10. Alexander TD, Chitguppi C, Collopy S, Murphy K, Lavergne P, Patel P, Khoury T, Rabinowitz M, Nyquist GG, Rosen MR, Farrell CJ, Karsy M, Evans JJ (2022). Surgical Outcomes of Endoscopic Transsphenoidal Pituitary Adenoma Resection in Elderly Versus Younger Patients. J Neurol Surg B Skull Base, 83(4), 405-410.
  11. Chaskes MB, Barton B, Karsy M, Chitguppi C, McKnight T, McCambridge J, Flanders A, Toskala E, Rabinowitz MR, Nyquist GG, Farrell C, Rosen MR, Evans JJ (2022). An algorithm for sellar reconstruction following endoscopic transsphenoidal surgery for pituitary adenoma: A review of 582 cases. Int Forum Allergy Rhinol.
  12. Makarenko S, Alzahrani I, Karsy M, Deopujari C, Couldwell WT (2022). Outcomes and surgical nuances in management of giant pituitary adenomas: a review of 108 cases in the endoscopic era. J Neurosurg, 1-12.
  13. Hamrick FA, Karsy M, Bruggers CS, Putnam AR, Hedlund GL, Cheshier SH (2021). Correction to: Developmentally anomalous cerebellar encephalocele arising within the cerebellopontine angle and extending into the adjacent skull base in a pediatric patient. Childs Nerv Syst (37(12), p. 3977). Germany.
  14. Sabourin V, Lavergne P, Mazza J, Head J, Al-Saiegh F, Stefanelli T, Karsy M, Evans JJ (2021). Internal Neurolysis for the Treatment of Trigeminal Neuralgia: A Systematic Review. World Neurosurg, 158, e829-e842.
  15. Yu S, Taghvaei M, Collopy S, Piper K, Karsy M, Lavergne P, Barton B, Chitguppi C, DSouza G, Rosen MR, Nyquist GG, Rabinowitz M, Farrell CJ, Evans JJ (2021). Evaluation of early postoperative day 1 discharge after endoscopic endonasal pituitary adenoma resection. J Neurosurg, 1-10.
  16. Khanna O, Fathi Kazerooni A, Farrell CJ, Baldassari MP, Alexander TD, Karsy M, Greenberger BA, Garcia JA, Sako C, Evans JJ, Judy KD, Andrews DW, Flanders AE, Sharan AD, Dicker AP, Shi W, Davatzikos C (2021). Machine Learning Using Multiparametric Magnetic Resonance Imaging Radiomic Feature Analysis to Predict Ki-67 in World Health Organization Grade I Meningiomas. Neurosurgery, 89(5), 928-936.
  17. Nguyen S, Cox P, Campbell JM, Brockmeyer DL, Karsy M (2021). Evaluating the utility and quality of large administrative databases in pediatric spinal neurosurgery research. Childs Nerv Syst, 37(10), 2993-3001.
  18. Nguyen S, Kim RB, Cox P, Gamboa NT, Karsy M, Couldwell WT, Menacho ST (2021). Impact of modified Frailty Index-11 (mFI-11) on postoperative complications in patients undergoing transsphenoidal resection of pituitary tumors: Analysis of 2006-2014 ACS-NSQIP database. J Clin Neurosci, 92, 22-26.
  19. Piper KJ, Karsy M, Barton B, Rabinowitz M, Rosen MR, Nyquist GG, Evans JJ, Tjoumakaris S, Farrell CJ (2021). Management of Coincident Pituitary Macroadenoma and Cavernous Carotid Aneurysm: A Systematic Literature Review. J Neurol Surg Rep, 82(3), e25-e31.
  20. Alexander TD, Collopy S, Yu S, Karsy M, Chitguppi C, Farrell CJ, Evans JJ (2021). Perioperative Outcomes of a Hydrocortisone Protocol after Endonasal Surgery for Pituitary Adenoma Resection. J Neurol Surg B Skull Base, 83(4), 383-389.
  21. Siu A, Rangarajan S, Karsy M, Farrell CJ, Nyquist G, Rosen M, Evans JJ (2021). Predictive Clinical and Surgical Factors Associated with Recurrent Apoplexy in Pituitary Adenomas. J Neurol Surg B Skull Base, 83(Suppl 2), e591-e597.
  22. Hamrick FA, Karsy M, Bruggers CS, Putnam AR, Hedlund GL, Cheshier SH (2021). Developmentally anomalous cerebellar encephalocele arising within the cerebellopontine angle and extending into the adjacent skull base in a pediatric patient. Childs Nerv Syst, 37(9), 2943-2947.
  23. Hunsaker JC, Khan M, Gamblin A, Karsy M, Couldwell WT (2021). Use of a Surgical Stepdown Protocol for Cost Reduction After Transsphenoidal Pituitary Adenoma Resection: A Case Series. World Neurosurg, 152, e476-e483.
  24. Kim RB, Scoville JP, Karsy M, Lim S, Jensen RL, Menacho ST (2021). Work relative value units and perioperative outcomes in patients undergoing brain tumor surgery. Neurosurg Rev, 45, 719-728.
  25. Piper K, Beldick SR, Karsy M, Allawh T, Shirodkar M, Miller J, Kiriakidou M, Curtis M, Evans JJ (2021). Granulomatosis with polyangiitis masquerading as pituitary adenoma with apoplexy. Mod Rheumatol Case Rep, 5(2), 342-346.
  26. Hunsaker J, Khan M, Makarenko S, Evans J, Couldwell W, Karsy M (2021). Prediction of Readmission and Complications After Pituitary Adenoma Resection via the National Surgical Quality Improvement Program (NSQIP) Database. Cureus, 13(5), e14809.
  27. Khan M, Farnsworth B, Pope BR, Sherrod B, Karsy M (2021). Impact of Hospital Volume on Outcome After Surgical Treatment for Hydrocephalus: A U.S. Population Study From the National Inpatient Sample. Cureus, 13(2), e13617.
  28. Piper K, DePledge L, Karsy M, Cobbs C (2021). Glioma Stem Cells as Immunotherapeutic Targets: Advancements and Challenges. Front Oncol, 11, 615704.
  29. Khan M, Harper J, Hunsaker JC, Kraus KL, Adogwa O, Mukherjee D, Kang A, Swartz K, Origitano TC, Guan J, Karsy M (2020). Letter: Evaluating the Role of Advanced Practice Providers in Neurosurgery. [Letter to the editor]. Neurosurgery, 88(3), E285-E287.
  30. Abou-Al-Shaar H, Cohen MA, Bi WL, Gozal YM, Alzhrani G, Karsy M, Al-Mefty O, Couldwell WT (2020). Surgical Management of Multifocal Trigeminal Schwannomas. Oper Neurosurg (Hagerstown), 19(6), 659-666.
  31. Kim RB, Wilkerson C, Karsy M, Joyce E, Rolston JD, Couldwell WT, Mahan MA (2020). Prolonged Length of Stay and Risk of Unplanned 30-Day Readmission After Elective Spine Surgery: Propensity Score-Matched Analysis of 33,840 Patients. Spine (Phila Pa 1976), 45(18), 1260-1268.
  32. Cohen MA, Abou-Al-Shaar H, Gozal YM, Karsy M, Alzhrani G, Shelton C, Couldwell WT (2019). Internal Auditory Canal Variability: Anatomic Variation Affects Cisternal Facial Nerve Visualization. Oper Neurosurg (Hagerstown), 19(3), E251-E258.
  33. Eli IM, Karsy M, Brodke DS, Bachus KN, Couldwell WT, Dailey AT, Mazur MD (2019). Restabilization of the Occipitocervical Junction After a Complete Unilateral Condylectomy: A Biomechanical Comparison of Unilateral and Bilateral Fixation Techniques. Oper Neurosurg (Hagerstown), 19(2), 157-164.
  34. Hardy J, Karsy M, Makarenko S, Ward M, Couldwell WT (2020). Hemorrhagic Fibrous Dysplasia with Acute Neurological Decline: Case Report and Review of the Literature. World Neurosurg, 140, 71-75.
  35. Karsy M, Kim R, Azab M, Harper J, Guan J, Eli I, Couldwell W (2020). Higher Admission D-Dimer Values Are Associated With an Increased Risk of Nonroutine Discharge in Neurosurgery Patients. Cureus, 12(7), e9425.
  36. Karsy M, Chan AK, Mummaneni PV, Virk MS, Bydon M, Glassman SD, Foley KT, Potts EA, Shaffrey CI, Shaffrey ME, Coric D, Asher AL, Knightly JJ, Park P, Fu KM, Slotkin JR, Haid RW, Wang M, Bisson EF (2020). Outcomes and Complications With Age in Spondylolisthesis: An Evaluation of the Elderly From the Quality Outcomes Database. Spine (Phila Pa 1976), 45(14), 1000-1008.
  37. Gamboa NT, Karsy M, Iyer RR, Bollo RJ, Schmidt RH (2020). Stereotactic laser interstitial thermal therapy for brainstem cavernous malformations: two preliminary cases. Acta Neurochir (Wien), 162(7), 1771-1775.
  38. Dossani R, Karsy M, Waqas M, Menger R, Guthikonda B (2020). A Survey of Applicant Views Regarding the Neurosurgical Fellowship Application Process. World Neurosurg, 139, e373-e382.
  39. Grandhi R, Karsy M, Taussky P, Ricker CN, Malhotra A (2020). Reduced 2-year aneurysm retreatment and costs among patients treated with flow diversion versus non-flow diversion embolization: A Premier Healthcare Database retrospective cohort study. PLoS One, 15(6), e0234478.
  40. Abou-Al-Shaar H, Krisht KM, Cohen MA, Abunimer AM, Neil JA, Karsy M, Alzhrani G, Couldwell WT (2020). Cranio-Orbital and Orbitocranial Approaches to Orbital and Intracranial Disease: Eye-Opening Approaches for Neurosurgeons. Front Surg, 7, 1.
  41. Wilde H, Gamblin AS, Reese J, Garry JG, Guan J, Mortenson J, Flis A, Rosenbluth JP, Karsy M, Bisson EF, Dailey AT (2019). The Effect of Hospital Transfer on Patient Outcomes After Rehabilitation for Spinal Injury. World Neurosurg, 133, e76-e83.
  42. Karsy M, Azab MA, Harper J, Abou-Al-Shaar H, Guan J, Eli I, Brock AA, Ormond RD, Hosokawa PW, Gouripeddi R, Butcher R, Cole CD, Menacho ST, Couldwell WT (2019). Evaluation of a D-Dimer Protocol for Detection of Venous Thromboembolism. World Neurosurg, 133, e774-e783.
  43. Wilde H, Twitchell S, Reese J, Guan J, Eli IM, Karsy M, Taussky P, Grandhi R, Schmidt RH, Couldwell WT (2019). Evaluation of disease severity and treatment intensity as cost drivers for ruptured intracranial aneurysms. Acta Neurochir (Wien), 162(1), 157-167.
  44. Bounajem MT, Karsy M, Jensen RL (2019). Liquid biopsies for the diagnosis and surveillance of primary pediatric central nervous system tumors: a review for practicing neurosurgeons. Neurosurg Focus, 48(1), E8.
  45. Mahan MA, Abou-Al-Shaar H, Karsy M, Warner W, Yeoh S, Palmer CA (2019). Pathologic remodeling in human neuromas: insights from clinical specimens. Acta Neurochir (Wien), 161(12), 2453-2466.
  46. Achey RL, Karsy M, Azab MA, Scoville J, Kundu B, Bowers CA, Couldwell WT (2019). Improved Surgical Safety via Intraoperative Navigation for Transnasal Transsphenoidal Resection of Pituitary Adenomas. J Neurol Surg B Skull Base, 80(6), 626-631.
  47. Eli I, Guan J, Karsy M, Mazur MD, Dailey A (2019). A Case of Ventral Spinal Cord Herniation from a Chronic Dural-pleural Fistula Resulting in Thoracic Myelopathy. Cureus, 11(11), e6123.
  48. Baker C, Karsy M, Couldwell WT (2019). Resection of Pituitary Tumor with Lateral Extension to the Temporal Fossa: The Toothpaste Extrusion Technique. Cureus, 11(10), e5953.
  49. Patel SK, Gozal YM, Saleh MS, Gibson JL, Karsy M, Mandybur GT (2019). Spinal cord stimulation failure: evaluation of factors underlying hardware explantation. J Neurosurg Spine, 1-6.
  50. Karsy M, Wilde H, Rolston JD (2019). In Reply: Evaluating the Landscape of Clinical Research in Neurosurgery. Neurosurgery, 85(4), E795.
  51. Gamblin A, Garry JG, Wilde HW, Reese JC, Sherrod B, Karsy M, Guan J, Mortenson J, Flis A, Rosenbluth JP, Bisson E, Dailey A (2019). Cost Analysis of Inpatient Rehabilitation after Spinal Injury: A Retrospective Cohort Analysis. Cureus, 11(9), e5747.
  52. Twitchell S, Wilde HW, Taussky P, Karsy M, Grandhi R (2019). Initial Treatment for Unruptured Intracranial Aneurysm and Its Follow-up: A Cost Analysis of Pipeline Flow Diverters versus Coiling. Cureus, 11(9), e5692.
  53. Karsy M, Guan J, Eli I, Brock AA, Menacho ST, Park MS (2019). The effect of supplementation of vitamin D in neurocritical care patients: RandomizEd Clinical TrIal oF hYpovitaminosis D (RECTIFY). J Neurosurg, 1-10.
  54. Wilde HW, Reese JC, Azab MA, Karsy M, Guan J, Rolston JD (2018). Evaluating the Landscape of Clinical Research in Neurosurgery. Neurosurgery, 85(3), E485-E493.
  55. Karsy M, Jensen MR, Guan J, Ravindra VM, Bisson EF, Couldwell WT (2018). EQ-5D Quality-of-Life Analysis and Cost-Effectiveness After Skull Base Meningioma Resection. Neurosurgery, 85(3), E543-E552.
  56. Karsy M, Taussky P, Grandhi R (2019). Letter to the Editor. Using Markov modeling to analyze endovascular coiling versus the Pipeline embolization device. J Neurosurg, 1-2.
  57. Ravindra VM, Karsy M, Lanpher A, Bollo RJ, Griauzde J, Scott RM, Couldwell WT, Smith ER (2019). A national analysis of 9655 pediatric cerebrovascular malformations: effect of hospital volume on outcomes. J Neurosurg Pediatr, 1-10.
  58. Foster CH, Karsy M, Jensen MR, Guan J, Eli I, Mahan MA (2018). Trends and Cost-Analysis of Lower Extremity Nerve Injury Using the National Inpatient Sample. Neurosurgery, 85(2), 250-256.
  59. Ahmad FU, Bisson EF, Burks SS, Chang JJ, Chugh AJ, Ct I, Frerich JM, Gersey ZC, Hendricks BK, Karsy M, Kasliwal M, Krause KL, Manzano GR, Morgan CD, Snyder LA, Swinney CC, Than KD, Theodotou CB, Veeravagu A, Ventura J (2019). Spine. Oper Neurosurg (Hagerstown), 17(Suppl 2), S153-S181.
  60. Karsy M, Hawryluk G (2019). Modern Medical Management of Spinal Cord Injury. Curr Neurol Neurosci Rep, 19(9), 65.
  61. Sherrod BA, Gamboa NT, Wilkerson C, Wilde H, Azab MA, Karsy M, Jensen RL, Menacho ST (2019). Effect of patient age on glioblastoma perioperative treatment costs: a value driven outcome database analysis. J Neurooncol, 143(3), 465-473.
  62. Karsy M, Bisson EF (2019). Surgical Versus Nonsurgical Treatment of Lumbar Spondylolisthesis. Neurosurg Clin N Am, 30(3), 333-340.
  63. Reese JC, Twitchell S, Wilde H, Azab MA, Guan J, Karsy M, Couldwell WT (2019). Analysis of Treatment Cost Variation Among Multiple Neurosurgical Procedures Using the Value-Driven Outcomes Database. World Neurosurg, 126, e914-e920.
  64. Karsy M, Akbari SH, Limbrick D, Leuthardt EC, Evans J, Smyth MD, Strahle J, Leonard J, Cheshier S, Brockmeyer DL, Bollo RJ, Kestle JR, Honeycutt J, Donahue DJ, Roberts RA, Hansen DR, Riva-Cambrin J, Sutherland G, Gallagher C, Hader W, Starreveld Y, Hamilton M, Duhaime AC, Jensen RL, Chicoine MR (2019). Evaluation of pediatric glioma outcomes using intraoperative MRI: a multicenter cohort study. J Neurooncol, 143(2), 271-280.
  65. Karsy M, Bowers CA, Scoville J, Kundu B, Azab MA, Gee JM, Guan J, Couldwell WT (2018). Evaluation of Complications and Costs During Overlapping Transsphenoidal Surgery in the Treatment of Pituitary Adenoma. Neurosurgery, 84(5), 1104-1111.
  66. Ronna B, Guan J, Karsy M, Service J, Ekins A, Jensen R (2019). A Survey of Neurosurgery Residency Program Coordinators: Their Roles, Responsibilities, and Perceived Value. Cureus, 11(4), e4457.
  67. Wilde H, Azab MA, Abunimer AM, Abou-Al-Shaar H, Karsy M, Guan J, Menacho ST, Jensen RL (2019). Evaluation of cost and survival in intracranial gliomas using the Value Driven Outcomes database: a retrospective cohort analysis. J Neurosurg, 132(4), 1006-1016.
  68. Sherrod B, Karsy M, Guan J, Brock AA, Eli IM, Bisson EF, Dailey AT (2018). Spine trauma and spinal cord injury in Utah: a geographic cohort study utilizing the National Inpatient Sample. J Neurosurg Spine, 31(1), 93-102.
  69. Abunimer AM, Abou-Al-Shaar H, Azab MA, Karsy M, Guan J, Kestle JR, Couldwell WT (2018). Transsphenoidal Approaches for Microsurgical Resection of Pituitary Adenomas in Pediatric Patients. World Neurosurg, 123, e186-e193.
  70. Karsy M, Watkins R, Jensen MR, Guan J, Brock AA, Mahan MA (2018). Trends and Cost Analysis of Upper Extremity Nerve Injury Using the National (Nationwide) Inpatient Sample. World Neurosurg, 123, e488-e500.
  71. Reese JC, Karsy M, Twitchell S, Bisson EF (2017). Analysis of Anterior Cervical Discectomy and Fusion Healthcare Costs via the Value-Driven Outcomes Tool. Neurosurgery, 84(2), 485-490.
  72. Azab MA, OHagan M, Abou-Al-Shaar H, Karsy M, Guan J, Couldwell WT (2018). Safety and Outcome of Transsphenoidal Pituitary Adenoma Resection in Elderly Patients. World Neurosurg, 122, e1252-e1258.
  73. Awad AW, Kilburg C, Karsy M, Couldwell WT, Taussky P (2019). Change in the angle of the anterior genu is associated with occlusion rate after Pipeline flow diversion. J Neurosurg, 1-5.
  74. Twitchell S, Karsy M, Gozal YM, Davidson C, Couldwell WT, Brockmeyer D (2019). Two-stage surgical treatment for a giant sellar psammomatoid juvenile ossifying fibroma: case report. J Neurosurg Pediatr, 1-5.
  75. Karsy M, Park MS, Bekelis K, Braca JA 3rd, Nahed BV, Colen CB, Barbaro NM, Berger MS, Mukherjee D (2018). Commentary: Deficiencies in Socioeconomic Training During Neurosurgical Training. Neurosurgery, 84(1), E79-E85.
  76. Karsy M, Azab MA, Guan J, Couldwell WT, Rolston JD (2018). The Impact of Specialization in Journal Networks and Scholarship. World Neurosurg, 120, e349-e356.
  77. Avila SV, Noy BV, Karsy M, Alexander M, Rolston JD (2018). Bilateral blunt cerebrovascular injury resulting in direct carotid-cavernous fistulae: A case report and review of the literature. Surg Neurol Int, 9, 229.
  78. Abou-Al-Shaar H, Azab MA, Karsy M, Guan J, Couldwell WT, Jensen RL (2018). Assessment of Costs in Open Microsurgery and Stereotactic Radiosurgery for Intracranial Meningiomas. World Neurosurg, 119, e357-e365.
  79. Abou-Al-Shaar H, Azab MA, Karsy M, Guan J, Alzhrani G, Gozal YM, Jensen RL, Couldwell WT (2018). Assessment of costs in open surgery and stereotactic radiosurgery for vestibular schwannomas. J Neurosurg, 131(2), 561-568.
  80. Guan J, Karsy M, Bisson EF, Couldwell WT (2017). Patient-Level Factors Influencing Hospital Costs and Short-Term Patient-Reported Outcomes After Transsphenoidal Resection of Sellar Tumors. Neurosurgery, 83(4), 726-731.
  81. Abou-Al-Shaar H, Alzhrani G, Gozal YM, Karsy M, Couldwell WT (2018). Hyperglycemic Nonketotic Signal Changes of the Striatum: An Unusual Complication in the Setting of Neurosurgical Procedures. World Neurosurg, 118, 177-180.
  82. Guan J, Karsy M, Brock AA, Couldwell WT, Kestle JRW, Jensen RL, Dailey AT, Bisson EF, Schmidt RH (2018). Analysis of an overlapping surgery policy change on costs in a high-volume neurosurgical department. J Neurosurg, 131(3), 903-910.
  83. Karsy M, Guan J, Abou-Al-Shaar H, Eli IM, Kundu B, Bisson EF, Couldwell WT, Dossani RH (2018). Letter to the Editor. Effect of facility costs in the treatment of neurosurgical patients using the Value Driven Outcome database. [Letter to the editor]. J Neurosurg, 129(3), 841-842.
  84. Karsy M, Brock AA, Rolston JD (2018). Hiding in Plain Sight: Underreporting of Clinical Trial Results in Neurology. Neurosurgery, 83(3), E96.
  85. Guan J, Karsy M, Brock AA, Couldwell WT, Schmidt RH (2018). Overlapping Surgery: 2 Years Later. Neurosurgery, 65(CN_suppl_1), 55-57.
  86. Karsy M, Henderson F, Tenny S, Guan J, Amps JW, Friedman AH, Spiotta AM, Patel S, Kestle JRW, Jensen RL, Couldwell WT (2017). Attitudes and opinions of US neurosurgical residents toward research and scholarship: a national survey. J Neurosurg, 131(1), 252-263.
  87. Arslan E, Gokdagli F, Bozdag H, Vatansever D, Karsy M (2018). Abnormal Pap smear frequency and comparison of repeat cytological follow-up with colposcopy during patient management: the importance of pathologist's guidance in the management. North Clin Istanb, 6(1), 69-74.
  88. Guan J, Karsy M, Brock AA, Couldwell WT, Kestle JRW, Jensen RL, Dailey AT, Schmidt RH (2017). Impact of a more restrictive overlapping surgery policy: an analysis of pre- and postimplementation complication rates, resident involvement, and surgical wait times at a high-volume neurosurgical department. J Neurosurg, 129(2), 515-523.
  89. Gamboa NT, Karsy M, Gamboa JT, Yoon NK, Driscoll MJ, Sonnen JA, Salzman KL, Jensen RL (2018). Preoperative and intraoperative perfusion magnetic resonance imaging in a RELA fusion-positive anaplastic ependymoma: A case report. Surg Neurol Int, 9, 144.
  90. Sommer T, Karsy M, Driscoll MJ, Jensen RL (2018). Varicella-Zoster Virus Infection and Osteomyelitis of the Skull. World Neurosurg, 115, 297-300.
  91. Karsy M, Harmer JR, Guan J, Brock AA, Ravindra VM, Chung LS, Tkach A, Majersik JJ, Park MS, Schmidt RH (2018). Outcomes in adults with cerebral venous sinus thrombosis: A retrospective cohort study. J Clin Neurosci, 53, 34-40.
  92. Abou-Al-Shaar H, Gozal YM, Alzhrani G, Karsy M, Shelton C, Couldwell WT (2018). Cerebral venous sinus thrombosis after vestibular schwannoma surgery: a call for evidence-based management guidelines. Neurosurg Focus, 45(1), E4.
  93. Guan J, Karsy M, Brock AA, Eli IM, Manton GM, Ledyard HK, Hawryluk GWJ, Park MS (2017). Vitamin D status and 3-month Glasgow Outcome Scale scores in patients in neurocritical care: prospective analysis of 497 patients. J Neurosurg, 128(6), 1635-1641.
  94. Karsy M, Azab MA, Abou-Al-Shaar H, Guan J, Eli I, Jensen RL, Ormond DR (2018). Clinical potential of meningioma genomic insights: a practical review for neurosurgeons. Neurosurg Focus, 44(6), E10.
  95. Twitchell S, Karsy M, Guan J, Couldwell WT, Taussky P (2018). Sequelae and management of radiation vasculopathy in neurosurgical patients. J Neurosurg, 1-9.
  96. Karsy M, Yoon N, Boettcher L, Jensen R, Shah L, MacDonald J, Menacho ST (2018). Surgical treatment of glioblastoma in the elderly: the impact of complications. J Neurooncol, 138(1), 123-132.
  97. Karsy M, Patel DM, Bollo RJ (2018). Trapped ventricle after laser ablation of a subependymal giant cell astrocytoma complicated by intraventricular gadolinium extravasation: case report. J Neurosurg Pediatr, 21(5), 523-527.
  98. Karsy M, Ravindra VM, Bollo RJ (2018). Letter to the Editor. Role of dysplastic and genetic mutations during the formation of cerebral aneurysms in infants. J Neurosurg Pediatr, 21(5), 543-544.
  99. Twitchell S, Karsy M, Reese J, Guan J, Couldwell WT, Dailey A, Bisson EF (2018). Assessment of cost drivers and cost variation for lumbar interbody fusion procedures using the Value Driven Outcomes database. Neurosurg Focus, 44(5), E10.
  100. Twitchell S, Abou-Al-Shaar H, Reese J, Karsy M, Eli IM, Guan J, Taussky P, Couldwell WT (2018). Analysis of cerebrovascular aneurysm treatment cost: retrospective cohort comparison of clipping, coiling, and flow diversion. Neurosurg Focus, 44(5), E3.
  101. Karsy M, Patel DM, Halvorson K, Mortimer V, Bollo RJ (2018). Anterior two-thirds corpus callosotomy via stereotactic laser ablation. Neurosurg Focus, 44(VideoSuppl2), V2.
  102. Karsy M, Guan J, Huang LE (2017). Prognostic role of mitochondrial pyruvate carrier in isocitrate dehydrogenase-mutant glioma. J Neurosurg, 130(1), 56-66.
  103. Karsy M, Burnett B, Di Ieva A, Cusimano MD, Jensen RL (2017). Microvascularization of Grade I meningiomas: effect on tumor volume, blood loss, and patient outcome. J Neurosurg, 128(3), 657-666.
  104. Karsy M, Abou-Al-Shaar H, Bowers CA, Schmidt RH (2016). Treatment of idiopathic intracranial hypertension via stereotactic placement of biventriculoperitoneal shunts. J Neurosurg, 130(1), 136-144.
  105. Karsy M, Palmer CA, Mahan MA (2018). Pathologic Remodeling of Endoneurial Tubules in Human Neuromas. Cureus, 10(1), e2087.
  106. Abou-Al-Shaar H, Karsy M, Ravindra V, Joyce E, Mahan MA (2018). Acute repair of traumatic pan-brachial plexus injury: technical considerations and approaches. Neurosurg Focus, 44(VideoSuppl1), V4.
  107. Karsy M, Gillespie DL, Horn KP, Burrell LD, Yap JT, Jensen RL (2018). Correlation of Glioma Proliferation and Hypoxia by Luciferase, Magnetic Resonance, and Positron Emission Tomography Imaging. Methods Mol Biol, 1742, 301-320.
  108. Augustin E, Karsy M, Bryan J, Guan J, Schmidt RH (2017). Air Transport of a Patient With Impending Cerebral Herniation From Tension Pneumocephalus. Air Med J, 37(1), 71-73.
  109. Karsy M, Raheja A, Eli I, Guan J, Couldwell WT (2017). Clinical Outcomes with Transcranial Resection of the Tuberculum Sellae Meningioma. World Neurosurg, 108, 748-755.
  110. Guan J, Brock AA, Karsy M, Couldwell WT, Schmidt MH, Kestle JRW, Jensen RL, Dailey AT, Schmidt RH (2016). Managing overlapping surgery: an analysis of 1018 neurosurgical and spine cases. J Neurosurg, 127(5), 1096-1104.
  111. Karsy M, Guan J, Brock AA, Amin A, Park MS (2017). Emerging Technologies in Flow Diverters and Stents for Cerebrovascular Diseases. Curr Neurol Neurosci Rep, 17(12), 96.
  112. Garber ST, Karsy M, Kestle JRW, Siddiqi F, Spanos SP, Riva-Cambrin J (2016). Comparing Outcomes and Cost of 3 Surgical Treatments for Sagittal Synostosis: A Retrospective Study Including Procedure-Related Cost Analysis. Neurosurgery, 81(4), 680-687.
  113. Awad AW, Karsy M, Sanai N, Spetzler R, Zhang Y, Xu Y, Mahan MA (2017). Impact of removed tumor volume and location on patient outcome in glioblastoma. J Neurooncol, 135(1), 161-171.
  114. Guan J, Karsy M, Schmidt MH, Dailey AT, Bisson EF (2017). Multivariable analysis of factors affecting length of stay and hospital charges after single-level corpectomy. J Clin Neurosci, 44, 279-283.
  115. Raheja A, Karsy M, Eli I, Guan J, Couldwell WT (2017). Endonasal Operative Corridor Expansion by Sphenoidal Pneumosinus Dilatans in Tuberculum Sellae Meningiomas. World Neurosurg, 106, 686-692.
  116. Guan J, Karsy M, Couldwell WT, Schmidt RH, Taussky P, Park MS (2017). Association of travel distance and cerebral aneurysm treatment. Surg Neurol Int, 8, 210.
  117. Karsy M, Brock AA, Guan J, Bisson EF, Couldwell WT (2017). Assessment of Cost Drivers in Transsphenoidal Approaches for Resection of Pituitary Tumors Using the Value-Driven Outcome Database. World Neurosurg, 105, 818-823.
  118. Guan J, Karsy M, Brock AA, Couldwell WT, Schmidt RH (2016). Overlapping Surgery: A Review of the Controversy, the Evidence, and Future Directions. Neurosurgery, 64(CN_suppl_1), 110-113.
  119. Karsy M, Jensen MR, Cole K, Guan J, Brock A, Cole C (2017). Thoracolumbar Cortical Screw Placement with Interbody Fusion: Technique and Considerations. Cureus, 9(7), e1419.
  120. Guan J, Karsy M, Brock AA, Eli IM, Ledyard HK, Hawryluk GWJ, Park MS (2016). A prospective analysis of hypovitaminosis D and mortality in 400 patients in the neurocritical care setting. J Neurosurg, 127(1), 1-7.
  121. Guan J, Karsy M, Couldwell WT, Schmidt RH, Taussky P, MacDonald JD, Park MS (2016). Factors influencing management of unruptured intracranial aneurysms: an analysis of 424 consecutive patients. J Neurosurg, 127(1), 96-101.
  122. Guan J, Karsy M, Schmidt M, Dailey AT, Bisson E (2017). Multivariable Analysis of Factors Affecting Length of Stay and Hospital Charges After Atlantoaxial Fusion. Cureus, 9(4), e1173.
  123. Karsy M, Brock A, Guan J, Taussky P, Kalani MY, Park MS (2017). Neuroprotective strategies and the underlying molecular basis of cerebrovascular stroke. Neurosurg Focus, 42(4), E3.
  124. Karsy M, Guan J, Cohen AL, Jensen RL, Colman H (2017). New Molecular Considerations for Glioma: IDH, ATRX, BRAF, TERT, H3 K27M. Curr Neurol Neurosci Rep, 17(2), 19.
  125. Karsy M, Hawryluk G (2016). Pharmacologic Management of Acute Spinal Cord Injury. Neurosurg Clin N Am, 28(1), 49-62.
  126. France JC, Karsy M, Harrop JS, Dailey AT (2016). Return to Play after Cervical Spine Injuries: A Consensus of Opinion. Global Spine J, 6(8), 792-797.
  127. Karsy M, Guan J, Ravindra VM, Stilwill S, Mahan MA (2016). Diagnostic Quality of Magnetic Resonance Imaging Interpretation for Peripheral Nerve Sheath Tumors: Can Malignancy Be Determined? J Neurol Surg A Cent Eur Neurosurg, 77(6), 495-504.
  128. Ravindra VM, Karsy M, Schmidt RH, Taussky P, Park MS, Bollo RJ (2016). Rapid de novo aneurysm formation after clipping of a ruptured middle cerebral artery aneurysm in an infant with an MYH11 mutation. J Neurosurg Pediatr, 18(4), 463-470.
  129. Ducis K, Guan J, Karsy M, Bollo RJ (2016). Preoperative evaluation and surgical decision-making in pediatric epilepsy surgery. Transl Pediatr, 5(3), 169-179.
  130. Sivakumar W, Karsy M, Brock A, Schmidt RH (2016). Postoperative Pain Control with the Fentanyl Patch and Continuous Paravertebral Anesthetic Infusion after Posterior Occipitocervical Junction Surgery. Cureus, 8(6), e645.
  131. Karsy M, Raheja A, Guan J, Osborn AG, Couldwell WT (2016). Scalp Arteriovenous Malformation with Concomitant, Flow-Dependent Malformation and Aneurysm. World Neurosurg, 90, 708.e5-708.e9.
  132. Guan J, Karsy M, Brock A, Couldwell WT (2016). The Utility of Ankle-Brachial Index as a Predictor of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage. World Neurosurg, 89, 139-46.
  133. Karsy M, Guan J, Jensen R, Huang LE, Colman H (2015). The Impact of Hypoxia and Mesenchymal Transition on Glioblastoma Pathogenesis and Cancer Stem Cells Regulation. World Neurosurg, 88, 222-236.
  134. Guan J, Karsy M, Eli I, Bisson EF, McNally S, Taussky P, Park MS (2015). Increased Incidence of Hypovitaminosis D Among Patients Requiring Treatment for Cerebral Aneurysms. World Neurosurg, 88, 15-20.
  135. Karsy M, Guan J, Cohen A, Colman H, Jensen RL (2016). Medical Management of Meningiomas: Current Status, Failed Treatments, and Promising Horizons. Neurosurg Clin N Am, 27(2), 249-60.
  136. Guan J, Karsy M, Ducis K, Bollo RJ (2016). Surgical strategies for pediatric epilepsy. Transl Pediatr, 5(2), 55-66.
  137. Karsy M, Guan J, Ducis K, Bollo RJ (2016). Emerging surgical therapies in the treatment of pediatric epilepsy. Transl Pediatr, 5(2), 67-78.
  138. Karsy M, Hoang N, Barth T, Burt L, Dunson W, Gillespie DL, Jensen RL (2015). Combined Hydroxyurea and Verapamil in the Clinical Treatment of Refractory Meningioma: Human and Orthotopic Xenograft Studies. World Neurosurg, 86, 210-9.
  139. Krisht KM, Karsy M, Shah LM, Schmidt MH, Dailey AT (2016). Unusual brachial plexus lesion: Hematoma masquerading as a peripheral nerve sheath tumor. Surg Neurol Int, 7(Suppl 3), S64-6.
  140. Guan J, Karsy M, Schmidt MH, Bisson EF (2015). Impact of Preoperative Hematocrit Level on Length of Stay after Surgery on the Lumbar Spine. Global Spine J, 5(5), 391-5.
  141. Karsy M, Guan J, Sivakumar W, Neil JA, Schmidt MH, Mahan MA (2015). The genetic basis of intradural spinal tumors and its impact on clinical treatment. Neurosurg Focus, 39(2), E3.
  142. Karsy M (2015). Erratum: A practical review of prognostic correlations of molecular biomarkers in glioblastoma. Neurosurg Focus (38(6), pp. E13). United States.
  143. Karsy M, Sonnen J, Couldwell WT (2015). Authors' reply to letter to the editor regarding "coincident pituitary adenoma and sellar meningioma". [Letter to the editor]. Acta Neurochir (Wien), 157(3), 555.
  144. Karsy M, Neil JA, Guan J, Mahan MA, Colman H, Jensen RL (2015). A practical review of prognostic correlations of molecular biomarkers in glioblastoma. Neurosurg Focus, 38(3), E4.
  145. Karsy M, Sonnen J, Couldwell WT (2014). Coincident pituitary adenoma and sellar meningioma. [Letter to the editor]. Acta Neurochir (Wien), 157(2), 231-3.
  146. Krisht KM, Karsy M, Ray WZ, Dailey AT (2015). Extraspinal type I dural arteriovenous fistula with a lumbosacral lipomyelomeningocele: a case report and review of the literature. Case Rep Neurol Med, 2015, 526321.
  147. Nguyen ML, Stevens E, LaFargue CJ, Karsy M, Pua TL, Gorelick C, Tedjarati SS, Pradhan TS (2014). Routine cystoscopy after robotic gynecologic oncology surgery. JSLS, 18(3).
  148. Karsy M, Huang T, Kleinman G, Karpel-Massler G (2014). Molecular, histopathological, and genomic variants of glioblastoma. Front Biosci (Landmark Ed), 19, 1065-87.
  149. Karsy M, Albert L, Murali R, Jhanwar-Uniyal M (2014). The impact of arsenic trioxide and all-trans retinoic acid on p53 R273H-codon mutant glioblastoma. Tumour Biol, 35(5), 4567-80.
  150. Sami A, Karsy M (2013). Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding. Tumour Biol, 34(4), 1991-2002.
  151. England B, Huang T, Karsy M (2013). Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme. Tumour Biol, 34(4), 2063-74.
  152. Huang T, Karsy M, Zhuge J, Zhong M, Liu D (2013). B-Raf and the inhibitors: from bench to bedside. J Hematol Oncol, 6, 30.
  153. Karsy M, Arslan E, Moy F (2012). Current Progress on Understanding MicroRNAs in Glioblastoma Multiforme. Genes Cancer, 3(1), 3-15.
  154. Karsy M, Gelbman M, Shah P, Balumbu O, Moy F, Arslan E (2013). Established and emerging variants of glioblastoma multiforme: review of morphological and molecular features. Folia Neuropathol, 50(4), 301-21.
  155. Jhanwar-Uniyal M, Albert L, McKenna E, Karsy M, Rajdev P, Braun A, Murali R (2010). Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways. Adv Enzyme Regul, 51(1), 164-70.
  156. Karsy M, Albert L, Tobias ME, Murali R, Jhanwar-Uniyal M (2010). All-trans retinoic acid modulates cancer stem cells of glioblastoma multiforme in an MAPK-dependent manner. Anticancer Res, 30(12), 4915-20.
  157. Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M (2009). Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. Int J Oncol, 35(4), 731-40.
  158. Albert L, Karsy M, Murali R, Jhanwar-Uniyal M (2009). Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme. Cancer Genomics Proteomics, 6(5), 255-61.