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Alex Shcheglovitov, PhD

Languages spoken: English, Russian, Ukrainian

Academic Information

Departments: Neurobiology - Assistant Professor, Bioengineering - Adjunct Assistant Professor, Psychiatry - Adjunct Assistant Professor

Divisions: Adult Psychiatry

Academic Office Information

alexsh@neuro.utah.edu

Education History

Postdoctoral Training Stanford University
Neuroscience/Stem Cell Biology
Postdoctoral Training
Postdoctoral Training Department of Pharmacology, University of Virginia
Biophysics/Molecular Biology
Postdoctoral Training
Doctoral Training Bogomoletz Institute of Physiology
Biophysics
Ph.D.
Graduate Training National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"
Biophysics
M.S.
Undergraduate National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"
Applied Physics
B.S.

Selected Publications

  1. Shcheglovitov A, Rao M, Yoo A (2018). Special issue on stem cell and tissue engineering in development, disease, and repair. Dev Dyn, 248(1), 7-9.
  2. Eckle VS, Shcheglovitov A, Vitko I, Dey D, Yap CC, Winckler B, Perez-Reyes E equally contributed authors (2014). "Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility.". J Physiol, 592(Pt 4), 795-809.
  3. Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer JF, Dolmetsch RE (2013). "SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients.". Nature, 503(7475), 267-71.
  4. Krey JF, Pasca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE (2013). "Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons.". Nat Neurosci, 16(2), 201-9.
  5. Shcheglovitov A, Vitko I, Lazarenko RM, Orestes P, Todorovic SM, Perez-Reyes E corresponding authors (2012). "Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Ca(v)2.3 calcium channels.". J Gen Physiol, 139(3), 219-34.
  6. Pasca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Pasca AM, Cord B, Palmer TD, Chikahisa S, Nishino S, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE (2011). "Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.". Nat Med, 17(12), 1657-62.
  7. Yoo AS, Sun AX, Li L, Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR equally contributed authors (2011). "MicroRNA-mediated conversion of human fibroblasts to neurons.". Nature, 476(7359), 228-31.
  8. Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schule B, Dolmetsch RE, Langston W, Palmer TD, Pera RR (2011). "LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.". Cell Stem Cell, 8(3), 267-80.
  9. Park CY, Shcheglovitov A, Dolmetsch R (2010). "The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels.". Science, 330(6000), 101-5.
  10. Shcheglovitov A, Vitko I, Bidaud I, Baumgart JP, Navarro-Gonzalez MF, Grayson TH, Lory P, Hill CE, Perez-Reyes E equally contributed authors (2008). "Alternative splicing within the I-II loop controls surface expression of T-type Ca(v)3.1 calcium channels.". FEBS Lett, 582(27), 3765-70.
  11. Vitko I, Shcheglovitov A, Baumgart JP, Arias-Olguin II, Murbartian J, Arias JM, Perez-Reyes E (2008). "Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity.". PLoS One, 3(10), e3560.
  12. Shcheglovitov A, Kostyuk P, Shuba Y (2007). "Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels.". Biochim Biophys Acta, 1768(6), 1406-19.
  13. Shcheglovitov A, Zhelay T, Vitko Y, Osipenko V, Perez-Reyes E, Kostyuk P, Shuba Y (2005). "Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels.". Biochem Pharmacol, 69(5), 841-54.

Global Impact

Education History

Type School Degree
Doctoral Training Bogomoletz Institute of Physiology
Biophysics
Ph.D.
Graduate Training National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"
Biophysics
M.S.
Undergraduate National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute"
Applied Physics
B.S.