Education History
| Research Fellow |
Cardiovascular Research Institute, University of California, San Francisco School of Medicine |
Postdoctoral Research Fellow |
|---|---|---|
| Postdoctoral Fellowship |
Baylor College of Medicine |
Postdoctoral Fellow |
| Residency |
University of Arizona Health Sciences Center |
Resident |
| Internship |
University of Arizona Health Sciences Center |
Intern |
| Professional Medical |
University of Colorado School of Medicine |
MD |
| Undergraduate |
Rice University |
BA |
Selected Publications
Journal Article
- Fike CD, Aschner JL, Avachat C, Birnbaum AK, Sherwin CMT (2023). Multi-dose enteral L-citrulline administration in premature infants at risk of developing pulmonary hypertension associated with bronchopulmonary dysplasia. J Perinatol, 44(2), 280-287. (Read full article)
- Douglass MS, Kaplowitz MR, Zhang Y, Fike CD (2023). Impact of l-citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells. Pulm Circ, 13(2), e12221. (Read full article)
- Fike CD, Avachat C, Birnbaum AK, Aschner JL, Sherwin CM (2022). Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension. Paediatr Drugs, 25(1), 87-96. (Read full article)
- Douglass M, Dikalova A, Kaplowitz MR, Zhang Y, Cunningham G, Summar M, Fike CD (2021). Folic acid, either solely or combined with L-citrulline, improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs. Physiol Rep, 9(21), e15096. (Read full article)
- Douglass MS, Zhang Y, Kaplowitz MR, Fike CD (2021). L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells. Pulm Circ, 11(2), 20458940211006289. (Read full article)
- McClellan EB, Wang Z, Albertine KH, Kaplowitz MR, Zhang Y, Fike CD (2020). l-Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs. Pediatr Pulmonol, 55(10), 2762-2772. (Read full article)
- Dikalova A, Aschner JL, Kaplowitz MR, Cunningham G, Summar M, Fike CD (2020). Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs. Am J Physiol Lung Cell Mol Physiol, 318(4), L762-L772. (Read full article)
Review
- Fike CD, Aschner JL (2023). Pharmacotherapy for Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia: Past, Present, and Future. [Review]. Pharmaceuticals (Basel), 16(4). (Read full article)
- Rashid J, Kumar SS, Job KM, Liu X, Fike CD, Sherwin CMT (2020). Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review. [Review]. Paediatr Drugs, 22(3), 279-293. (Read full article)
Patent
- Summar, Marshall, Barr, Frederic E., Fike, Candice D., Aschner, Judy L (2010). Therapeutic treatment for lung conditions. U.S. Patent No. 09707788.7-2107 PCT/US2009032824. Washington, D.C.:U.S. Patent and Trademark Office.