My N. Helms

My N. Helms, PhD

Languages spoken: English

Academic Information

Departments Primary - Internal Medicine

Divisions: Public Health

Education History

Undergraduate University of North Carolina at Chapel Hill
 BS
Doctoral Training Dartmouth Medical School
 PhD
Postdoctoral Fellowship Dartmouth Medical School
 Postdoctoral Fellow
Postdoctoral Fellowship Emory University School of Medicine
 Postdoctoral Fellow
Postdoctoral Fellowship Emory University School of Medicine
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. My N. Helms, Camila Coca, Charles A. Downs, and Wei W Redox Sensitivities of ¿- and ¿- epithelial sodium channel (ENaC) subunits. The Journal of biological chemistry,
  2. Grant GJ, Liou TG, Paine R 3rd, Helms M (2020). High-mobility group box-1 increases epithelial sodium channel activity and inflammation via the receptor for advanced glycation end products. American journal of physiology. Cell physiology, 318(3), C570-C580. (Read full article)
  3. Garett J. Grant, Robert Paine III, Theodore G. Liou, and My N. Helm High Mobility Group Box-1 Increases Epithelial Sodium Channel Activity and Inflammation via the Receptor for Advanced Glycation End Products. American journal of physiology. Lung cellular and molecular physiology,
  4. Patrice Mimche, Ethan Goh, Wei-Jun Qian, and My N. Helm Increased Epithelial Sodium Channel (ENaC) Activity Protects Preterm Lungs from Hyperoxia-Induced Lung Injury. American journal of physiology. Lung cellular and molecular physiology,
  5. Liou TG, Adler FR, Cahill BC, Cox DR, Cox JE, Grant GJ, Hanson KE, Hartsell SC, Hatton ND, Helms MN, Jensen JL, Kartsonaki C, Li Y, Leung DT, Marvin JE, Middleton EA, Osburn-Staker SM, Packer KA, Shakir SM, Sturrock AB, Tardif KD, Warren KJ, Waddoups LJ, Weaver LJ, Zimmerman E, Paine R 3r (2021). SARS-CoV-2 innate effector associations and viral load in early nasopharyngeal infection. Physiological reports, 9(4), e14761. (Read full article)
  6. Grant GJ, Mimche PN, Paine R 3rd, Liou TG, Qian WJ, Helms M (2021). Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen-induced lung injury. American journal of physiology. Lung cellular and molecular physiology, 321(1), L29-L41. (Read full article)
  7. Sturrock A, Zimmerman E, Helms M, Liou TG, Paine R 3r (2021). Hypoxia induces expression of angiotensin-converting enzyme II in alveolar epithelial cells: Implications for the pathogenesis of acute lung injury in COVID-19. Physiological reports, 9(9), e14854. (Read full article)
  8. Zhang T, Day NJ, Gaffrey M, Weitz KK, Attah K, Mimche PN, Paine R 3rd, Qian WJ, Helms M (2022). Regulation of hyperoxia-induced neonatal lung injury via post-translational cysteine redox modifications. Redox biology, 55, 102405. (Read full article)
  9. Warren KJ, Beck EM, Callahan SJ, Helms MN, Middleton E, Maddock S, Carr JR, Harris D, Blagev DP, Lanspa MJ, Brown SM, Paine R 3r (2023). Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype. Respiratory research, 24(1), 162. (Read full article)
  10. Zheng H, Helms MN, Zou C, Zimmerman E, Feng Y, Yang (2025). Furin-mediated modification is required for epithelial sodium channel-activating activity of soluble (pro)renin receptor in cultured collecting duct cells. American journal of physiology. Renal physiology, 328(6), F766-F774. (Read full article)
  11. Egal ESA, Kamdem SD, Yoshigi M, Yang CC, Pellizzari S, Kameni EM, Helms MN, Assassi S, Henkemeyer M, Frech TM, Mimche P (2024). EphB2 Receptor Promotes Dermal Fibrosis in Systemic Sclerosis. Arthritis & rheumatology (Hoboken, N.J.), 76(8), 1303-1316. (Read full article)
  12. Zimmerman E, Sturrock A, Reilly CA, Burrell-Gerbers KL, Warren K, Mir-Kasimov M, Zhang MA, Pierce MS, Helms MN, Paine R 3r (2024). Aryl Hydrocarbon Receptor Activation in Pulmonary Alveolar Epithelial Cells Limits Inflammation and Preserves Lung Epithelial Cell Integrity. Journal of immunology (Baltimore, Md., 213(5), 600-611. (Read full article)

Review

  1. Egal ESA, Scarini JF, de Lima-Souza RA, Lavareze L, Fernandes PM, Emerick C, Gonçalves MT, Helms MN, Altemani A, Mariano F (2022). Tumor microenvironment in salivary gland carcinomas: An orchestrated state of chaos. Oral oncology, 127, 105777. (Read full article)
  2. Lavareze L, Scarini JF, de Lima-Souza RA, Emerick C, Sales de Sá R, Aquino IG, Fernandes PM, Gonçalves MT, Helms MN, Altemani A, Egal ESA, Mariano F (2022). Salivary gland cancer in the setting of tumor microenvironment: Translational routes for therapy. Critical reviews in oncology/hematology, 171, 103605. (Read full article)
  3. Tao Z, Helms MN, Leach BCB, Wu (2022). Molecular insights into the multifaceted functions and therapeutic targeting of high mobility group box 1 in metabolic diseases. Journal of cellular and molecular medicine, 26(14), 3809-3815. (Read full article)
  4. Damas II, Lavareze L, Scarini JF, de Lima-Souza RA, Emerick C, Gonçalves MT, Figueiredo-Maciel T, Vieira GS, Kimura TC, Aquino IG, Paiva JPG, Helms MN, Mariano FV, Altemani A, Egal ES (2023). Immunopathological insights into villitis of unknown etiology on the basis of transplant immunology. Placenta, 131, 49-57. (Read full article)

Editorial

  1. Helms MN, Liou T (2022). Spotlighting "Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps": A New Catch in Cystic Fibrosis?. American journal of respiratory cell and molecular biology, 66(1), 5-7. (Read full article)