Donna J. Cross

Donna J. Cross, PhD

Languages spoken: English

Academic Information

Departments Primary - Radiology & Imaging Sciences

Lab

Dr. Cross is a research associate professor at the University of Utah where she heads the Neuroimaging and Biotechnology Laboratory. Her research passion is to make a significant impact on the therapeutic and diagnostic options for neurological disorders and dementia through imaging. Her research includes investigations such as a new therapeutic approach for brain injury and neurodegeneration using microtubule-stabilizing agents as well as the use of MR-guided, focused ultrasound to treat spinal cord injury. She is an active study section participant for NIH, RSNA, and the Alzheimer's Association. Dr. Cross was the 2022/2023 president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI Brain Imaging Council (BIC).

Education History

Fellowship University of Washington
 Senior Fellow
University of Michigan
 PhD
Graduate Training University of Michigan
 Postbaccalaureate Studies
University of Michigan
 Postbaccalaureate Studies
Undergraduate University of Michigan
 BSE
Other Training Michigan State University

Selected Publications

Journal Article

  1. Andre JB, Oztek MA, Anzai Y, Wilson GJ, Mossa-Basha M, Hippe DS, Hoff MN, Cross DJ, Minoshima S (2023). Evaluation of 3-dimensional stereotactic surface projection rendering of arterial spin labeling data in a clinical cohort. J Neuroimaging, 33(6), 933-940. (Read full article)
  2. Pendergraft LT, Marzluff JM, Cross DJ, Shimizu T, Templeton CN (2023). American crows that excel at tool use activate neural circuits distinct from less talented individuals. Nat Commun, 14(1), 6539. (Read full article)
  3. Bischof GN, Cross DJ (2022). Brain Trauma Imaging. J Nucl Med, 64(1), 20-29. (Read full article)
  4. Komori S, Cross DJ, Mills M, Ouchi Y, Nishizawa S, Okada H, Norikane T, Thientunyakit T, Anzai Y, Minoshima S (2022). Deep-learning prediction of amyloid deposition from early-phase amyloid positron emission tomography imaging. Ann Nucl Med, 36(10), 913-921. (Read full article)
  5. Minoshima S, Cross D, Thientunyakit T, Foster NL, Drzezga A (2022). (18)F-FDG PET Imaging in Neurodegenerative Dementing Disorders: Insights into Subtype Classification, Emerging Disease Categories, and Mixed Dementia with Copathologies. J Nucl Med, 63(Suppl 1), 2S-12S. (Read full article)
  6. Pendergraft LT, Marzluff JM, Cross DJ, Shimizu T, Templeton CN (2021). American Crow Brain Activity in Response to Conspecific Vocalizations Changes When Food Is Present. Front Physiol, 12, 766345. (Read full article)
  7. Cross CG, Payne AH, Hawryluk GW, Haag-Roeger R, Cheeniyil R, Brady D, Oden H, Minoshima S, Cross DJ, Anzai Y (2021). Technical Note: Quantification of blood-spinal cord barrier permeability after application of magnetic resonance-guided focused ultrasound in spinal cord injury. Med Phys, 48(8), 4395-4401. (Read full article)
  8. Cross DJ, Huber BR, Silverman MA, Cline MM, Gill TB, Cross CG, Cook DG, Minoshima S (2021). Intranasal Paclitaxel Alters Alzheimer's Disease Phenotypic Features in 3xTg-AD Mice. J Alzheimers Dis, 83(1), 379-394. (Read full article)
  9. Meabon JS, Cook DG, Yagi M, Terry GE, Cross DJ, Muzi M, Pagulayan KF, Logsdon AF, Schindler AG, Ghai V, Wang K, Fallen S, Zhou Y, Kim TK, Lee I, Banks WA, Carlson ES, Mayer C, Hendrickson RC, Raskind MA, Marshall DA, Perl DP, Keene CD, Peskind ER (2020). Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure. J Neurol Sci, 417, 117049. (Read full article)
  10. Swift KN, Marzluff JM, Templeton CN, Shimizu T, Cross DJ (2020). Brain activity underlying American crow processing of encounters with dead conspecifics. Behav Brain Res, 385, 112546. (Read full article)
  11. Cherrier MM, Cross DJ, Higano CS, Minoshima S (2018). Changes in cerebral metabolic activity in men undergoing androgen deprivation therapy for non-metastatic prostate cancer. Prostate Cancer Prostatic Dis, 21(3), 394-402. (Read full article)
  12. Payne AH, Hawryluk GW, Anzai Y, Oden H, Ostlie MA, Reichert EC, Stump AJ, Minoshima S, Cross DJ (2018). Magnetic resonance imaging-guided focused ultrasound to increase localized blood-spinal cord barrier permeability. Neural Regen Res, 12(12), 2045-2049. (Read full article)
  13. Cline MM, Ostlie MA, Cross CG, Garwin GG, Minoshima S, Cross DJ (2017). Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze. J Vis Exp, (125). (Read full article)
  14. Morbelli S, Arbizu J, Booij J, Chen MK, Chetelat G, Cross DJ, Djekidel M, Drzezga A, Ekmekcioglu O, Garibotto V, Hesse S, Ishii K, Jafari L, Lammertsma AA, Law I, Mathews D, Minoshima S, Mosci K, Pagani M, Pappata S, Silverman DH, Signore A, Van De Giessen E, Villemagne V, Barthel H, European Association of Nuclear Medicine EANM and of the Society of Nuclear Medicine and Molecular Imaging SNMMI (2016). Erratum to: The need of standardization and of large clinical studies in an emerging indication of [18 F]FDG PET: the autoimmune encephalitis. Eur J Nucl Med Mol Imaging, 44(3), 559-560. (Read full article)
  15. Cline MM, Yumul JC, Hysa L, Murra D, Garwin GG, Cook DG, Ladiges WC, Minoshima S, Cross DJ (2016). Novel application of a Radial Water Tread maze can distinguish cognitive deficits in mice with traumatic brain injury. Brain Res, 1657, 140-147. (Read full article)
  16. Meabon JS, Huber BR, Cross DJ, Richards TL, Minoshima S, Pagulayan KF, Li G, Meeker KD, Kraemer BC, Petrie EC, Raskind MA, Peskind ER, Cook DG (2016). Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Sci Transl Med, 8(321), 321ra6. (Read full article)

Review

  1. Minoshima S, Cross D (2022). Application of artificial intelligence in brain molecular imaging. [Review]. Ann Nucl Med, 36(2), 103-110. (Read full article)
  2. Minoshima S, Mosci K, Cross D, Thientunyakit T (2021). Brain [F-18]FDG PET for Clinical Dementia Workup: Differential Diagnosis of Alzheimer's Disease and Other Types of Dementing Disorders. [Review]. Semin Nucl Med, 51(3), 230-240. (Read full article)

Book Chapter

  1. Cross DJ, Komori S, Minoshima S (2021). Artificial Intelligence for Brain Molecular Imaging. In PET Clin (17, pp. 57-64). United States. (Read full article)

Editorial

  1. Morbelli S, Arbizu J, Booij J, Chen MK, Chetelat G, Cross DJ, Djekidel M, Drzezga A, Ekmekcioglu O, Garibotto V, Hesse S, Ishii K, Jafari L, Lammertsma AA, Law I, Mathews D, Minoshima S, Mosci K, Pagani M, Pappata S, Silverman DH, Signore A, Van De Giessen E, Villemagne V, Barthel H, European Association of Nuclear Medicine EANM and of the Society of Nuclear Medicine and Molecular Imaging SNMMI (2016). The need of standardization and of large clinical studies in an emerging indication of [(18)F]FDG PET: the autoimmune encephalitis. Eur J Nucl Med Mol Imaging, 44(3), 353-357. (Read full article)