Education History
| Fellowship |
University of Utah, ARUP Laboratories |
Fellow |
|---|---|---|
| Postdoctoral Fellowship |
Huntsman Cancer Institute |
Postdoctoral Research Fellow |
| Doctoral Training |
University of Utah |
PhD |
| Undergraduate |
Utah State University |
BS |
Selected Publications
Journal Article
- Battistone B, Ghazaryan A, Tang WW, Air ZB, Tantalla J, Thompson J, Bauer KM, Barba C, Nelson M, Tran VTB, OMalley L, Ngo Q, Hernandez C, Thibeaux A, Ekiz HA, Voth WP, Rao DS, OConnell RM (2026). T-cell miR-155 regulates the response to tumor-specific mRNA vaccines in a murine model of acute myeloid leukemia. J Immunol.
- Nelson MC, OMalley LC, Lee SH, Bauer KM, Ghazaryan A, Tang WW, VanSant-Webb C, Tran VB, Hernandez C, Battistone B, Thibeaux A, Round JL, Drummond MJ, Ekiz HA, Evason KJ, Voth WP, OConnell RM (2026). MicroRNA-146a Protects against Hepatocellular Carcinoma through Suppression of CCL5. Cancer Res Commun.
- Tang WW, Battistone B, Bauer KM, Weis AM, Barba C, Fadlullah MZH, Ghazaryan A, Tran VB, Lee SH, Agir ZB, Nelson MC, Victor ES, Thibeaux A, Hernandez C, Tantalla J, Tan AC, Rao D, Williams M, Drummond MJ, Beswick EJ, Round JL, Ekiz HA, Voth WP, OConnell RM (2025). A microRNA-regulated transcriptional state defines intratumoral CD8(+) T cells that respond to immunotherapy. Cell Rep, 44(2), 115301.
- Ren JG, Xing B, Lv K, OKeefe RA, Wu M, Wang R, Bauer KM, Ghazaryan A, Burslem GM, Zhang J, OConnell RM, Pillai V, Hexner EO, Philips MR, Tong W (2023). RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. J Clin Invest, 133(12).
- Ghazaryan A, Wallace JA, Tang WW, Barba C, Lee SH, Bauer KM, Nelson MC, Kim CN, Stubben C, Voth WP, Rao DS, OConnell RM (2023). miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation. Front Genet, 14, 1192799.
- Thompson JW, Hu R, Huffaker TB, Ramstead AG, Ekiz HA, Bauer KM, Tang WW, Ghazaryan A, Round JL, Fujinami RS, OConnell RM (2022). MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation. J Immunol, 210(7), 926-934.
- Barba C, Ekiz HA, Tang WW, Ghazaryan A, Hansen M, Lee SH, Voth WP, OConnell RM (2023). Interferon Gamma-Inducible NAMPT in Melanoma Cells Serves as a Mechanism of Resistance to Enhance Tumor Growth. Cancers (Basel), 15(5).
- Bauer KM, Nelson MC, Tang WW, Chiaro TR, Brown DG, Ghazaryan A, Lee SH, Weis AM, Hill JH, Klag KA, Tran VB, Thompson JW, Ramstead AG, Monts JK, Marvin JE, Alexander M, Voth WP, Stephens WZ, Ward DM, Petrey AC, Round JL, OConnell RM (2022). CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis. JCI Insight, 7(19).
- Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, OConnell RM, Round JL (2020). Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep, 37(5), 109916.
- Petersen C, Bell R, Klag KA, Lee SH, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, OConnell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL (2018). T cell-mediated regulation of the microbiota protects against obesity. Science, 365(6451).
- Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, OConnell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL (2018). Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis. Cell Host Microbe, 25(2), 285-299.e8.
Review
- Blanchard Z, Brown EA, Ghazaryan A, Welm AL (2024). PDX models for functional precision oncology and discovery science. [Review]. Nat Rev Cancer, 25(3), 153-166.