John M. VanBuren

John M. VanBuren, PhD

Languages spoken: English

Academic Information

Departments Primary - Pediatrics , Adjunct - Family & Preventive Medicine , Adjunct - Population Health Sciences

Divisions: Critical Care , Public Health

Academic Office Information

John.VanBuren@hsc.utah.edu

Dr. John VanBuren grew up in Sycamore, Illinois and then attended Augustana College in Rock Island, Illinois where he graduated in 2011 with majors in Mathematics and Biology. After that, he attended the University of Iowa for Biostatistics where he received his Master’s degree in 2013 and Ph.D. in 2016. In his thesis, he created a model that analyzed replications of infectious disease spread for a population of participants with glaucoma.

He joined the Data Coordinating Center in the Department of Pediatric – Division of Critical Care as a Faculty Statistician. John specializes in Bayesian adaptive design. He currently works on several networks and projects including the Pediatric Emergency Care Applied Research Network (PECARN), the Collaborative Pediatric Critical Care Applied Research Network (CPCCRN), the Trial Innovation Network (TIN), the COllaborative, National QUality and Efficacy Registry (CONQUER), and other industry projects. When not working, John enjoys all the nature opportunities offered at Utah.

Education History

Doctoral Training University of Iowa
 PhD
University of Iowa
 MS
Undergraduate Augustana College
 BA

Selected Publications

Journal Article

  1. Luebker S, Frech T, Assassi S, Skaug B, Gordon JK, Lakin K, Bernstein EJ, Luo Y, Steen VD, Shah AA, Hummers LK, Richardson C, Moore DF, Khanna D, Castelino FV, Chung L, Kapoor P, Hant FN, Shanmugam VK, VanBuren JM, Alvey J, Harding M, Shah A, Makol A, Lebiedz-Odrobina D, Thomas JK, Volkmann ER, Molitor JA, Sandorfi N (2023). CONQUER Scleroderma: association of gastrointestinal tract symptoms in early disease with resource utilization. Rheumatology (Oxford), 62(10), 3433-3438. (Read full article)
  2. Nigrovic LE, Chun TH, Vargas SE, Caffrey AR, Halperin JJ, Race JA, Ott U, Morrison BL, Fuller BJ, VanBuren JM, Lyme Net P (2023). Comparative effectiveness and complications of intravenous ceftriaxone compared with oral doxycycline in Lyme meningitis in children: a multicentre prospective cohort study. BMJ Open, 13(2), e071141. (Read full article)
  3. Zantek ND, Steiner ME, VanBuren JM, Lewis RJ, Berry NS, Viele K, Krachey E, Dean JM, Nelson S, Spinella PC (2022). Design and logistical considerations for the randomized adaptive non-inferiority storage-duration-ranging CHIlled Platelet Study. Clin Trials, 20(1), 36-46. (Read full article)
  4. Mahajan P, VanBuren JM, Tzimenatos L, Cruz AT, Vitale M, Powell EC, Leetch AN, Pickett ML, Brayer A, Nigrovic LE, Dayan PS, Atabaki SM, Ruddy RM, Rogers AJ, Greenberg R, Alpern ER, Tunik MG, Saunders M, Muenzer J, Levine DA, Hoyle JD, Lillis KG, Gattu R, Crain EF, Borgialli D, Bonsu B, Blumberg S, Anders J, Roosevelt G, Browne LR, Cohen DM, Linakis JG, Jaffe DM, Bennett JE, Schnadower D, Park G, Mistry RD, Glissmeyer EW, Cator A, Bogie A, Quayle KS, Ellison A, Balamuth F, Richards R, Ramilo O, Kuppermann N, Pediatric Emergency Care Applied Research Network PECARN (2022). Serious Bacterial Infections in Young Febrile Infants With Positive Urinalysis Results. Pediatrics, 150(4). (Read full article)
  5. Johnson AR, Pautler M, Burr JS, Abdelsamad N, VanBuren JM, Rigtrup LM, Dean JM, Rothwell E (2022). Using single IRB consultations to meet the educational needs of investigative teams. Contemp Clin Trials Commun, 29, 100971. (Read full article)
  6. VanBuren JM, Roalstad S, Kay MT, Zuspan SJ, Dean JM, Brulotte M (2022). Development of a risk assessment and risk management tool for an academic research organization. Contemp Clin Trials, 119, 106812. (Read full article)
  7. Maddux AB, VanBuren JM, Jensen AR, Holubkov R, Alvey JS, McQuillen P, Mourani PM, Meert KL, Burd RS, Eunice Kennedy Shriver National Institute of Child Health, Human Development Collaborative Pediatric Critical Care Research Network CPCCRN Assessment of Health-Related Quality of Life, Functional Outcomes after Pediatric Trauma Project Investigators (2022). Post-discharge rehabilitation and functional recovery after pediatric injury. Injury, 53(8), 2795-2803. (Read full article)
  8. Levine AC, OConnell KJ, Schnadower D, VanBuren TJM, Mahajan P, Hurley KF, Tarr P, Olsen CS, Poonai N, Schuh S, Powell EC, Farion KJ, Sapien RE, Roskind CG, Rogers AJ, Bhatt S, Gouin S, Vance C, Freedman SB, Pediatric Emergency Research Canada PERC the Pediatric Emergency Care Applied Research Network PECARN (2022). Derivation of the Pediatric Acute Gastroenteritis Risk Score to Predict Moderate-to-Severe Acute Gastroenteritis. J Pediatr Gastroenterol Nutr, 74(4), 446-453. (Read full article)
  9. Nishijima DK, VanBuren JM, Linakis SW, Hewes HA, Myers SR, Bobinski M, Tran NK, Ghetti S, Adelson PD, Roberts I, Holmes JF, Schalick WO 3rd, Dean JM, Casper TC, Kuppermann N, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network PECARN (2022). Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): a pilot randomized trial. Acad Emerg Med. (Read full article)
  10. Castelino FV, VanBuren JM, Startup E, Assassi S, Bernstein EJ, Chung L, Correia C, Evnin LB, Frech TM, Gordon JK, Hant FN, Hummers LK, Khanna D, Sandorfi N, Shah AA, Shanmugam VK, Steen V (2021). Baseline characteristics of systemic sclerosis patients with restrictive lung disease in a multi-center US-based longitudinal registry. Int J Rheum Dis, 25(2), 163-174. (Read full article)
  11. Bosson N, Hansen M, Gausche-Hill M, Lewis RJ, Wendelberger B, Shah MI, VanBuren JM, Wang HE (2021). Design of a novel clinical trial of prehospital pediatric airway management. Clin Trials, 19(1), 62-70. (Read full article)
  12. Hanlin ER, Chan HK, Hansen M, Wendelberger B, Shah MI, Bosson N, Gausche-Hill M, VanBuren JM, Wang HE (2022). Epidemiology of out-of-hospital pediatric airway management in the 2019 national emergency medical services information system data set. Resuscitation, 173, 124-133. (Read full article)
  13. Ward SL, VanBuren JM, Richards R, Holubkov R, Alvey JS, Jensen AR, Pollack MM, Burd RS (2022). Evaluating the association between obesity and discharge functional status after pediatric injury. J Pediatr Surg. (Read full article)
  14. Jensen AR, Evans LL, Meert KL, VanBuren JM, Richards R, Alvey JS, Holubkov R, Pollack MM, Burd RS, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network CPCCRN Assessment of Health-Related Quality of Life and Functional Outcomes after Pediatric Trauma Project Investigators (2021). Functional status impairment at six-month follow-up is independently associated with child physical abuse mechanism. Child Abuse Negl, 122, 105333. (Read full article)
  15. VanBuren JM, Casper TC, Nishijima DK, Kuppermann N, Lewis RJ, Dean JM, McGlothlin A, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network PECARN (2021). The design of a Bayesian adaptive clinical trial of tranexamic acid in severely injured children. Trials, 22(1), 769. (Read full article)
  16. Johnson AR, Rigtrup LM, VanBuren J, Rothwell E, Dean JM (2021). An Approach to Reviewing Local Context for Exception from Informed Consent Trials Using a Single IRB. Ethics Hum Res, 43(6), 42-48. (Read full article)
  17. Evans LL, Jensen AR, Meert KL, VanBuren JM, Richards R, Alvey JS, Carcillo JA, McQuillen PS, Mourani PM, Nance ML, Holubkov R, Pollack MM, Burd RS (2021). All body region injuries are not equal: Differences in pediatric discharge functional status based on Abbreviated Injury Scale (AIS) body regions and severity scores. J Pediatr Surg, 57, 739-746. (Read full article)
  18. Freedman SB, Finkelstein Y, Pang XL, Chui L, Tarr PI, VanBuren JM, Olsen C, Lee BE, Sapien R, OConnell K, Levine AC, Poonai N, Roskind C, Schuh S, Rogers A, Bhatt S, Gouin S, Mahajan P, Vance C, Hurley K, Powell EC, Farion KJ, Schnadower D, Pediatric Emergency Research Canada PERC and the Pediatric Emergency Care Applied Research Network PECARN (2021). Pathogen-Specific Effects of Probiotics in Children with Acute Gastroenteritis Seeking Emergency Care: A Randomized Trial. Clin Infect Dis. (Read full article)
  19. Gerald LB, Gerald JK, VanBuren JM, Lowe A, Guthrie CC, Klein EJ, Morrison A, Startup E, Denninghoff K (2021). Randomized trial of the feasibility of ED-initiated school-based asthma medication supervision (ED-SAMS). Pilot Feasibility Stud, 7(1), 179. (Read full article)
  20. Branch DW, VanBuren JM, Porter TF, Holmgren C, Holubkov R, Page K, Burchard J, Lam GK, Esplin MS (2021). Prediction and Prevention of Preterm Birth: A Prospective, Randomized Intervention Trial. Am J Perinatol, 40(10), 1071-1080. (Read full article)
  21. Burd RS, Jensen AR, VanBuren JM, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Health-Related Quality of Life and Functional Outcomes After Pediatric Trauma Investigators, Berg RA, Carcillo JA, Carpenter TC, Dean JM, Gaines B, Hall MW, McQuillen PS, Meert KL, Mourani PM, Nance ML, Yates AR (2021). Factors Associated With Functional Impairment After Pediatric Injury. JAMA Surg, 156(8), e212058. (Read full article)
  22. Linakis SW, Kuppermann N, Stanley RM, Hewes H, Myers S, VanBuren JM, Casper TC, Bobinski M, Ghetti S, Schalick WO 3rd, Nishijima DK, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network PECARN (2021). Enrollment with and without exception from informed consent in a pilot trial of tranexamic acid in children with hemorrhagic injuries. Acad Emerg Med, 28, 1421-1429. (Read full article)
  23. Schnadower D, OConnell KJ, VanBuren JM, Vance C, Tarr PI, Schuh S, Hurley K, Rogers AJ, Poonai N, Roskind CG, Bhatt SR, Gouin S, Mahajan P, Olsen CS, Powell EC, Farion K, Sapien RE, Chun TH, Freedman SB, Pediatric Emergency Care Applied Research Network and Pediatric Emergency Research Canada (2020). Association Between Diarrhea Duration and Severity and Probiotic Efficacy in Children With Acute Gastroenteritis. Am J Gastroenterol, 116(7), 1523-1532. (Read full article)
  24. Freedman SB, Roskind CG, Schuh S, VanBuren JM, Norris JG, Tarr PI, Hurley K, Levine AC, Rogers A, Bhatt S, Gouin S, Mahajan P, Vance C, Powell EC, Farion KJ, Sapien R, OConnell K, Poonai N, Schnadower D, Pediatric Emergency Research Canada and Pediatric Emergency Care Applied Research Networks (2021). Comparing Pediatric Gastroenteritis Emergency Department Care in Canada and the United States. Pediatrics, 147(6). (Read full article)
  25. Nishijima DK, Gosdin M, Naz H, Tancredi DJ, Hewes HA, Myers SR, Stanley RM, Adelson PD, Burd RS, Finkelstein Y, VanBuren J, Casper TC, Kuppermann N, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network PECARN (2020). Assessment of primary outcome measures for a clinical trial of pediatric hemorrhagic injuries. Am J Emerg Med, 43, 210-216. (Read full article)
  26. Florin TA, Ramilo O, Hoyle JD Jr, Jaffe DM, Tzimenatos L, Atabaki SM, Cohen DM, VanBuren JM, Mahajan P, Kuppermann N, Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network PECARN (2022). Radiographic Pneumonia in Febrile Infants 60 Days and Younger. Pediatr Emerg Care, 37(5), e221-e226. (Read full article)
  27. Hansen M, Bosson N, Gausche-Hill M, Shah MI, VanBuren JM, Wendelberger B, Wang H (2021). Critical Factors in Planning a Pediatric Prehospital Airway Trial. Prehosp Emerg Care, 1-13. (Read full article)
  28. Frech TM, VanBuren JM, Startup E, Assassi S, Bernstein EJ, Castelino FV, Chung L, Correia C, Gordon JK, Hant FN, Hummers L, Khanna D, Sandorfi N, Shah AA, Shanmugam VK, Steen V, Evnin L (2020). Does hand involvement in systemic sclerosis limit completion of patient-reported outcome measures? Clin Rheumatol, 40(3), 965-971. (Read full article)
  29. Schnadower D, Roskind CG, VanBuren JM, Powell EC, Norris JG, Tarr PI, Sapien RE, OConnell KJ, Chun TH, Rogers AJ, Bhatt SR, Mahajan P, Gorelick MH, Vance C, Dean JM, Freedman SB, Pediatric Emergency Care Applied Research Network PECARN (2020). Factors Associated With Nonadherence in an Emergency Department-based Multicenter Randomized Clinical Trial of a Probiotic in Children With Acute Gastroenteritis. J Pediatr Gastroenterol Nutr, 72(1), 24-28. (Read full article)
  30. Alpern ER, Kuppermann N, Blumberg S, Roosevelt G, Cruz AT, Nigrovic LE, Browne LR, VanBuren JM, Ramilo O, Mahajan P, PEDIATRIC EMERGENCY CARE APPLIED RESEARCH NETWORK PECARN (2021). Time to Positive Blood and Cerebrospinal Fluid Cultures in Febrile Infants ≤60 Days of Age. Hosp Pediatr, 10(9), 719-727. (Read full article)
  31. Garro A, Dash M, VanBuren JM, Nigrovic LE, for Pedi Lyme Net (2020). Development of a pediatric Lyme meningitis symptom measurement instrument using a Delphi technique. Ticks Tick Borne Dis, 11(4), 101418. (Read full article)
  32. Shanmugam VK, Frech TM, Steen VD, Hummers LK, Shah AA, Bernstein EJ, Khanna D, Gordon JK, Castelino FV, Chung L, Hant FN, Startup E, VanBuren JM, Evnin LB, Assassi S (2019). Collaborative National Quality and Efficacy Registry (CONQUER) for Scleroderma: outcomes from a multicenter US-based systemic sclerosis registry. Clin Rheumatol, 39(1), 93-102. (Read full article)
  33. Nishijima DK, Kuppermann N, Roberts I, VanBuren JM, Tancredi DJ (2019). The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial. Ann Emerg Med, 74(1), 79-87. (Read full article)
  34. Bennett EE, VanBuren J, Holubkov R, Bratton SL (2018). Presence of Invasive Devices and Risks of Healthcare-Associated Infections and Sepsis. J Pediatr Intensive Care, 7(4), 188-195. (Read full article)
  35. Nishijima DK, VanBuren J, Hewes HA, Myers SR, Stanley RM, Adelson PD, Barnhard SE, Bobinski M, Ghetti S, Holmes JF, Roberts I, Schalick WO 3rd, Tran NK, Tzimenatos LS, Michael Dean J, Kuppermann N, TIC-TOC Collaborators of the Pediatric Emergency Care Applied Research Network (2018). Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial. Trials, 19(1), 593. (Read full article)
  36. Curtis AM, VanBuren J, Cavanaugh JE, Warren JJ, Marshall TA, Levy SM (2018). Longitudinal associations between dental caries increment and risk factors in late childhood and adolescence. J Public Health Dent, 78(4), 321-328. (Read full article)
  37. Marshall TA, Curtis AM, Cavanaugh JE, VanBuren JM, Warren JJ, Levy SM (2018). Description of Child and Adolescent Beverage and Anthropometric Measures According to Adolescent Beverage Patterns. Nutrients, 10(8). (Read full article)
  38. Curtis AM, Cavanaugh JE, Levy SM, VanBuren J, Marshall TA, Warren JJ (2017). Examining caries aetiology in adolescence with structural equation modelling. Community Dent Oral Epidemiol, 46(3), 258-264. (Read full article)
  39. Tzimenatos L, Mahajan P, Dayan PS, Vitale M, Linakis JG, Blumberg S, Borgialli D, Ruddy RM, Van Buren J, Ramilo O, Kuppermann N, Pediatric Emergency Care Applied Research Network PECARN (2018). Accuracy of the Urinalysis for Urinary Tract Infections in Febrile Infants 60 Days and Younger. Pediatrics, 141(2). (Read full article)
  40. Warren JJ, Van Buren JM, Levy SM, Marshall TA, Cavanaugh JE, Curtis AM, Kolker JL, Weber-Gasparoni K (2017). Dental caries clusters among adolescents. Community Dent Oral Epidemiol, 45(6), 538-544. (Read full article)
  41. Haedtke C, Smith M, VanBuren J, Klein D, Turvey C (2017). The Characteristics of Pain in Patients Diagnosed with Depression and Heart Failure. Pain Manag Nurs, 18(6), 353-362. (Read full article)
  42. Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N, Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (2017). Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections. JAMA Pediatr, 171(11), e172927. (Read full article)
  43. Haedtke C, Smith M, VanBuren J, Klein D, Turvey C (2017). The Relationships Among Pain, Depression, and Physical Activity in Patients With Heart Failure. J Cardiovasc Nurs, 32(5), E21-E25. (Read full article)
  44. VanBuren J, Cavanaugh J, Marshall T, Warren J, Levy SM (2017). AIC identifies optimal representation of longitudinal dietary variables. J Public Health Dent, 77(4), 360-371. (Read full article)
  45. Marshall TA, Van Buren JM, Warren JJ, Cavanaugh JE, Levy SM (2017). Beverage Consumption Patterns at Age 13 to 17 Years Are Associated with Weight, Height, and Body Mass Index at Age 17 Years. J Acad Nutr Diet, 117(5), 698-706. (Read full article)
  46. Pettit KA, Kundert JR, VanBuren JM, Story WT, Buresh CT (2017). Close Together, Far Apart: an Assessment of the Public Health Needs of Three Geographically Proximate Communities in Central Haiti. J Health Care Poor Underserved, 28(2), 739-753. (Read full article)
  47. VanBuren J, Oleson JJ, Zamba GK, Wall M (2016). Integrating independent spatio-temporal replications to assess population trends in disease spread. Stat Med, 35(28), 5210-5221. (Read full article)

Review

  1. Opotowsky AR, Allen KY, Bucholz EM, Burns KM, Del Nido P, Fenton KN, Gelb BD, Kirkpatrick JN, Kutty S, Lambert LM, Lopez KN, Olivieri LJ, Pajor NM, Pasquali SK, Petit CJ, Sood E, VanBuren JM, Pearson GD, Miyamoto SD (2022). Pediatric and Congenital Cardiovascular Disease Research Challenges and Opportunities: JACC Review Topic of the Week. [Review]. J Am Coll Cardiol, 80(23), 2239-2250. (Read full article)

Other

  1. Burd RS, Jensen AR, VanBuren JM, Alvey JS, Richards R, Holubkov R, Pollack MM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network Assessment of Functional Outcomes and Health-Related Quality of Life after Pediatric Trauma Investigators (2021). Long-Term Outcomes after Pediatric Injury: Results of the Assessment of Functional Outcomes and Health-Related Quality of Life after Pediatric Trauma Study. J Am Coll Surg (233(6), pp. 666-675.e2). United States. (Read full article)
  2. Millar MM, Olson LM, VanBuren JM, Richards R, Pollack MM, Holubkov R, Berg RA, Carcillo JA, McQuillen PS, Meert KL, Mourani PM, Burd RS (2021). Incentive delivery timing and follow-up survey completion in a prospective cohort study of injured children: a randomized experiment comparing prepaid and postpaid incentives. BMC Med Res Methodol (21(1), p. 233). England. (Read full article)