Guillaume L. Hoareau

Guillaume L. Hoareau, PhD, DVM

Languages spoken: English, French, Spanish

Academic Information

Departments Primary - Emergency Medicine

Academic Office Information

Guillaume.Hoareau@utah.edu

Board Certification

  • European College of Veterinary Emergency and Critical Care
  • American College of Veterinary Emergency Critical Care

Dr. Hoareau is a veterinarian with board certification in Emergency and Critical Care and a Ph.D. in Integrative Pathobiology. His research focuses on acute care translational research with an interest in military resuscitation. Specifically, he studies novel therapeutic approaches to mitigate ischemia-reperfusion injury in hemorrhagic shock. He works toward preserving mitochondrial function, the essential cell machinery for energy production. He seeks to accelerate the transition of new therapies to clinical practice. Dr. Hoareau mentors trainees around all aspects of translational acute care research with a strong interest and commitment to diversity, equity, and inclusion. He is part of several pipelines for trainees from underrepresented minorities.

Education History

Undergraduate Levavasseur
 BSc (Hons)
Professional Other National Veterinary School of Toulouse
 DVM
Internship University of Pennsylvania School of Veterinary Medicine/Matthew J. Ryan Hospital
 Intern
Residency University of California, Davis/William R. Pritchard Veterinary Medical Teaching Hospital
 Resident
Doctoral Training University of California, Davis
 PhD
Postdoctoral Fellowship Travis Air Force Base/Henry M. Jackson Foundation for the Advancement of Military Medicine
 Postdoctoral Fellow
Research Fellow Travis Air Force Base/Oak Ridge Institute for Science and Education
 Postdoctoral Research Fellow

Selected Publications

Journal Article

  1. Kelly C, Palatinus H, Johnson R, Hunt-Smith T, Ewer N, Saint-Pierre L, Hoareau GL, Johnson MA, Youngquist S (2025). Nebulized Nitroglycerin Improves Carotid Blood Flow During Cardiopulmonary Resuscitation in a Swine Model of Cardiac Arrest. Prehospital emergency care, 1-10.
  2. Silverton NA, Hoareau GL, Kuck (2025). Cardiopulmonary Bypass and the Kidney: New Evidence for Old Foes. Anesthesiology, 142(6), 985-988.
  3. Huther A, Edwards TH, Jaramillo EL, Giles JT 3rd, Israel SK, Mison M, Ambrosius L, Kaiser T, Hoareau G (2024). The use of a kaolin-based hemostatic dressing to attenuate bleeding in dogs: A series of 4 cases. Journal of veterinary emergency and critical care (San Antonio, Tex.,
  4. Silverton NA, Lofgren LR, Kuck K, Stoddard GJ, Johnson R, Ramezani A, Hoareau G (2024). Near-infrared spectroscopy for kidney oxygen monitoring in a porcine model of hemorrhagic shock, hemodilution, and REBOA. Scientific reports, 14(1), 2646.
  5. Palatinus HN, Johnson MA, Wang HE, Hoareau GL, Youngquist S (2024). Early intramuscular adrenaline administration is associated with improved survival from out-of-hospital cardiac arrest. Resuscitation, 201, 110266.
  6. Edwards TH, Venn EC, Le TD, Grantham LE 2nd, Hogen T, Ford R, Ewer N, Gunville R, Carroll C, Taylor A, Hoareau G (2024). Comparison of Shelf-stable and Conventional Resuscitation Products in a Canine Model of Hemorrhagic Shock. The journal of trauma and acute care surgery,
  7. Brant-Zawadzki G, Hoareau GL, Stoecklein HH, Levin N, Selzman CH, Ciullo A, Tonna J, Kelly C, Jones J, Youngquist ST, Johnson M (2024). Successful Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) deployment by emergency medicine physicians for refractory non-traumatic cardiac arrest. Resuscitation plus, 20, 100784.
  8. Ryan MA, Ford R, Ewer N, Hall KE, Guillaumin J, Edwards TH, Venn EC, Grantham LE, Hoareau G (2024). Sidestream dark field video microscopy demonstrates shelf-stable blood products preserve the endothelial glycocalyx in a canine hemorrhagic shock model. American journal of veterinary research, 1-7.
  9. Weaver AJ Jr, Venn EC, Ford R, Ewer N, Hildreth KE, Williams CE, Duncan CE, Calhoun CL, Grantham LE, Hoareau GL, Edwards T (2024). Comparing the effects of various fluid resuscitative strategies on Glycocalyx damage in a canine hemorrhage model. Veterinary journal (London, England, 307, 106221.
  10. Gonzalez JM, Edwards TH, Hoareau GL, Snider E (2024). Refinement of machine learning arterial waveform models for predicting blood loss in canines. Frontiers in artificial intelligence, 7, 1408029.
  11. Edwards T, Gonzalez JM, Hernandez-Torres S, Venn E, Ford R, Ewer N, Hoareau GL, Holland L, Convertino VA, Snider (2024). Predicting blood loss volume in a canine model of hemorrhagic shock using arterial waveform machine learning analysis. American journal of veterinary research, 1-10.
  12. Li J, Balmaceda P, Ha T, Visker JR, Maalouf N, Kwan E, Hoareau GL, Accad M, Ranjan R, Selzman CH, Drakos SG, Shaw RM, Hong (2024). Cardiac bridging integrator 1 gene therapy rescues chronic non-ischemic heart failure in minipigs. NPJ Regenerative medicine, 9(1), 36.
  13. Khan MS, Smego D, Ishidoya Y, Hirahara AM, Offei E, Ruiz Castillo MS, Gharbia O, Li H, Palatinus JA, Krueger L, Hong T, Hoareau GL, Ranjan R, Selzman CH, Shaw RM, Dosdall D (2023). A canine model of chronic ischemic heart failure. American journal of physiology. Heart and circulatory physiology, 324(6), H751-H761.
  14. Patel N, Johnson MA, Vapniarsky N, Van Brocklin MW, Williams TK, Youngquist ST, Ford R, Ewer N, Neff LP, Hoareau G (2023). Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock. Scientific reports, 13(1), 4496.
  15. Haugland H, Gamberini L, Hoareau GL, Haenggi M, Greif R, Brede JR, REBOA OHCA expert panel and other Collaborator (2023). Resuscitative endovascular balloon occlusion of the aorta in out-of-hospital cardiac arrest - A Delphi consensus study for uniform data collection. Resuscitation plus, 16, 100485.
  16. Hilgart DR, Iversen MM, Peters AY, Zabriskie MS, Hoareau GL, Vapniarsky N, Clark GA, Shah LM, Rieke (2023). Non-invasive central nervous system assessment of a porcine model of neuropathic pain demonstrates increased latency of somatosensory-evoked potentials. Journal of neuroscience methods, 396, 109934.
  17. Hirahara AM, Khan MS, Ishidoya Y, Smego D, Roman O, Ranjan R, Krueger L, Hoareau G, Selzman CH, Dosdall D (2023). Canine Model of Ischemia-Induced Ventricular Tachycardia. The Journal of surgical research, 293, 196-203.
  18. Krulewitz N, Levin NM, Youngquist S, Kelly C, Hoareau G, Johnson MA, Ockerse (2023). Evaluation of esophageal injuries after defibrillation with transesophageal ultrasound probe in the mid-esophagus in pigs. The American journal of emergency medicine, 74, 14-16.
  19. Alexander MD, Hoareau G, Zabriskie MS, Palatinus H, Chakravarthula NR, Wang C, Johnson M (2023). Real-Time Monitoring and Modulation of Blood Pressure in a Rabbit Model of Ischemic Stroke. Journal of visualized experiments, (192),
  20. Patel NTP, Gaffley M, Leblanc MJR, Lane MR, Hoareau GL, Johnson MA, Jordan JE, Neff LP, Williams T (2022). Endovascular Perfusion Augmentation After Resuscitative Endovascular Balloon Occlusion of the Aorta Improves Renal Perfusion and Decreases Vasopressors. The Journal of surgical research, 279, 712-721.
  21. Lofgren LR, Hoareau GL, Kuck K, Silverton N (2022). Noninvasive and Invasive Renal Hypoxia Monitoring in a Porcine Model of Hemorrhagic Shock. Journal of visualized experiments, (188),
  22. Wheeler LR, Edwards TH, Heinz JA, Scott LLF, Grantham LE 2nd, Keesee JD, Henderson AF, Gerardo AC, Hoareau G, Bynum J (2022). Comparison of assessment of coagulation in healthy dogs by the TEG 6s and TEG 5000 viscoelastic analyzers. Journal of veterinary diagnostic investigation, 34(5), 780-788.
  23. Hoareau GL, Beyer CA, Caples CM, Spruce MW, Gilbert Z, Grayson JK, Neff LP, Williams TK, Johnson M (2020). Esmolol reduces myocardial injury induced by resuscitative endovascular balloon occlusion of the aorta (REBOA) in a porcine model of hemorrhagic shock. Injury, 51(10), 2165-2171.
  24. Abid M, Neff LP, Russo RM, Hoareau G, Williams TK, Grayson JK, DuBose JJ, Lendrum R, Johnson M (2020). Reperfusion repercussions: A review of the metabolic derangements following resuscitative endovascular balloon occlusion of the aorta. The journal of trauma and acute care surgery, 89(2S Suppl 2), S39-S44.
  25. Beyer CA, Burmeister DM, Gómez BI, Tercero J, Babcock E, Walker LE, Hoareau G, Sosnov J, Chung KK, Stewart I (2019). Point-of-Care Urinary Biomarker Testing for Risk Prediction in Critically Injured Combat Casualties. Journal of the American College of Surgeons, 229(5), 508-515.e1.
  26. Tibbits EM, Hoareau GL, Simon MA, Davidson AJ, DeSoucy ES, Faulconer ER, DuBose JJ, Neff LP, Grayson JK, Williams TK, Johnson M (2018). Location is everything: The hemodynamic effects of REBOA in Zone 1 versus Zone 3 of the aorta. The journal of trauma and acute care surgery, 85(1), 101-107.

Review

  1. Hall KE, Tucker C, Dunn JA, Webb T, Watts SA, Kirkman E, Guillaumin J, Hoareau GL, Pidcoke H (2024). Breaking barriers in trauma research: A narrative review of opportunities to leverage veterinary trauma for accelerated translation to clinical solutions for pets and people. Journal of clinical and translational science, 8(1), e74.
  2. Nwaduru C, Ovalle LA, Hoareau GL, Baker E, Buff M, Selim M, Baker TB, Zimmerman M (2024). Ectonucleotidases in Ischemia Reperfusion Injury: Unravelling the Interplay With Mitochondrial Dysfunction in Liver Transplantation. Transplantation proceedings, 56(7), 1598-1606.
  3. Youngquist ST, Tonna JE, Bartos JA, Johnson MA, Hoareau GL, Hutin A, Lamhaut (2020). Current Work in Extracorporeal Cardiopulmonary Resuscitation. Critical care clinics, 36(4), 723-735.

Letter

  1. Johnson MA, Hoareau G, Williams TK, Neff L (2020). Letter to the editor: Response to letter from Dr. Martin et al: Not ready for prime time: Intermittent versus partial REBOA for prolonged hemorrhage control in a highly lethal porcine injury model. The journal of trauma and acute care surgery, 88(6), e150-e151.

Other

  1. Hoareau GL, Beyer CA, Kashtan HW, Walker LE, Wilson C, Wishy A, Grayson JK, Stewart I (2021). Improvised Field Expedient Method for Renal Replacement Therapy in a Porcine Model of Acute Kidney Injury. Disaster medicine and public health preparedness, 15(6), 741-749.
  2. Hoareau GL, Beyer CA, Caples CA, Spruce MW, Kevin Grayson J, Neff LP, Williams TK, Johnson M (2020). Automated Partial Versus Complete Resuscitative Endovascular Balloon Occlusion of the Aorta for the Management of Hemorrhagic Shock in a Pig Model of Polytrauma: a Randomized Controlled Pilot Study. Military medicine, 185(11-12), e1923-e1930.
  3. Beyer CA, Hoareau GL, Kashtan HW, Wishy AM, Caples C, Spruce M, Grayson JK, Neff LP, Williams TK, Johnson M (2020). Resuscitative endovascular balloon occlusion of the aorta (REBOA) in a swine model of hemorrhagic shock and blunt thoracic injury. European journal of trauma and emergency surgery, 46(6), 1357-1366.