Tsegaselassie Workalemahu

Tsegaselassie Workalemahu, PhD, MS

Academic Information

Departments Primary - Obstetrics & Gynecology , Adjunct - Internal Medicine , Adjunct - Human Genetics

Divisions: Maternal Fetal Medicine , Epidemiology

Dr. Workalemahu is a genetic epidemiology researcher investigating causes of unexplained obstetric complications. Specifically, Dr. Workalemahu investigates the genetic factors related to pregnancy loss, stillbirth and other obstetric complications that are often linked with adverse health outcomes over one's lifetime. Presently, there are knowledge gaps regarding the causes of pregnancy loss and its recurrence. These knowledge gaps have prompted the use of diagnostic tests and treatments that increase cost, anxiety and may even cause harm without clear efficacy. If the genetic factors contributing to pregnancy complications are determined, expensive but non-specific, diagnostic evaluations and interventions for couples suffering the complications could be avoided. One of Dr. Workalemahu's studies is aimed at determining specific genetic mutations that cause pregnancy loss by conducting whole genome sequencing analysis of DNA from families. Dr. Workalemahu's other research interests include investigating placental epigenetic factors and genetics of complex chronic conditions such as cardiovascular diseases and diabetes.

Dr. Workalemahu received his bachelor’s degree in Mathematics from St. Francis University in Loretto, Pennsylvania. He received his doctoral degree in Epidemiology from the University of Washington in Seattle, Washington, and completed his post-doctoral training at the Eunice Kennedy Shriver National Institute of Child Health and Development in Bethesda, Maryland.

Education History

Undergraduate St. Francis University
 BSc (Hons)
Graduate Training Georgia State University
 MS
Graduate Training University of Washington
 PhD
Fellowship Eunice Kennedy Shriver National Institute of Child Health and Human Development
 Predoctoral Fellow
Postdoctoral Fellowship Eunice Kennedy Shriver National Institute of Child Health and Human Development
 Postdoctoral Fellow

Selected Publications

Journal Article

  1. Workalemahu T, Enquobahrie DA, Gelaye B, Thornton TA, Tekola-Ayele F, Sanchez SE, Garcia PJ, Palomino HG, Hajat A, Romero R, Ananth CV, Williams MA (2018). Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study. Am J Obstet Gynecol, 219(6), 617.e1-617.e17.
  2. Workalemahu T, Gelaye B, Berhane Y, Williams MA (2013). Physical activity and metabolic syndrome among Ethiopian adults. Am J Hypertens, 26(4), 535-40.
  3. Graff M, Ngwa JS, Workalemahu T, Homuth G, Schipf S, Teumer A, Völzke H, Wallaschofski H, Abecasis GR, Edward L, Francesco C, Sanna S, Scheet P, Schlessinger D, Sidore C, Xiao X, Wang Z, Chanock SJ, Jacobs KB, Hayes RB, Hu F, Van Dam RM, GIANT Consortium., Crout RJ, Marazita ML, Shaffer JR, Atwood LD, Fox CS, Heard-Costa NL, White C, Choh AC, Czerwinski SA, Demerath EW, Dyer TD, Towne B, Amin N, Oostra BA, Van Duijn CM, Zillikens MC, Esko T, Nelis M, Nikopensius T, Metspalu A, Strachan DP, Monda K, Qi L, North KE, Cupples LA, Gordon-Larsen P, Berndt SI (2013). Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet, 22(17), 3597-607.
  4. Chu AY, Workalemahu T, Paynter NP, Rose LM, Giulianini F, Tanaka T, Ngwa JS, CHARGE Nutrition Working Group., Qi Q, Curhan GC, Rimm EB, Hunter DJ, Pasquale LR, Ridker PM, Hu FB, Chasman DI, Qi L, DietGen Consortium. (2013). Novel locus including FGF21 is associated with dietary macronutrient intake. Hum Mol Genet, 22(9), 1895-902.
  5. Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo K, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen A AE, Westra HJ, Winkler TW, Workalemahu T, et a (2014). Defining the role of common variation in the genomic and biological architecture of adult human height. Nature genetics,
  6. Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Carola Zillikens M, Speliotes EK, Mägi R, Workalemahu T, et a (2010). Meta-analysis Identifies 13 Novel Loci Associated with Waist-Hip-Ratio and Reveals Sexual Dimorphism in the Genetic Basis of Fat Distribution. Nature genetics, 42(11), 937-48.
  7. Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, et a (2010). Association Analyses of 249,796 Individuals Reveal Eighteen New Loci Associated with Body Mass Index. Nature genetics, 41(11), 937-48.
  8. Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature genetics, 45(5), 501-12.
  9. Li Y, Qi Q, Workalemahu T, Hu FB, Qi (2012). Birth weight, genetic susceptibility, and adulthood risk of type 2 diabetes. Diabetes care, 35(12), 2479-84.
  10. Qi Q, Workalemahu T, Zhang C, Hu FB, Qi (2012). Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes. European heart journal, 33(3), 325-34.
  11. Rahman ML, Shrestha D, Workalemahu T, Wu J, Zhu C, Zhang C, Tekola-Ayele (2019). Maternal and Offspring Genetic Risk of Type 2 Diabetes and Offspring Birthweight Among African Ancestry Populations. The Journal of clinical endocrinology and metabolism,
  12. Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, et a (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518(7538), 197-206.
  13. Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, et a (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518(7538), 187-96.
  14. Allen HL, Estrada K, Guillaume L, Berndt SI, Weedon MN, Rivadeneira F, Willer C, Jackson AU, Vedantam S, Ferreira T, Wood A, Weyant RJ, Segrè, A, Raychaudhuri S, Speliotes EK, Wheeler E, Soranzo N, Park J-H, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Smith AV, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler T, Bhangale T, Goddard ME, Lo KS, Palmer C, Workalemahu T, et a (2010). Hundreds of Variants Influence Human Height and Cluster within Genomic Loci and Biological Pathways. Nature, 467(7317), 832-8.
  15. Workalemahu T, Enquobahrie DA, Gelaye B, Sanchez SE, Garcia PJ, Tekola-Ayele F, Hajat A, Thornton TA, Ananth CV, Williams M (2018). Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies. Placenta, 66, 8-16.
  16. Workalemahu T, Badon SE, Dishi-Galitzky M, Qiu C, Williams MA, Sorensen T, Enquobahrie D (2017). Placental genetic variations in vitamin D metabolism and birthweight. Placenta, 50, 78-83.
  17. Workalemahu T, Enquobahrie DA, Tadesse MG, Hevner K, Gelaye B, Sanchez SE, Williams M (2017). Genetic variations related to maternal whole blood mitochondrial DNA copy number: a genome-wide and candidate gene study. The journal of maternal-fetal & neonatal medicine, 30(20), 2433-2439.
  18. Workalemahu T, Enquobahrie DA, Yohannes E, Sanchez SE, Gelaye B, Qiu C, Williams M (2016). Placental telomere length and risk of placental abruption. The journal of maternal-fetal & neonatal medicine, 29(17), 2767-72.
  19. Workalemahu T, Enquobahrie DA, Gelaye B, Tadesse MG, Sanchez SE, Tekola-Ayele F, Hajat A, Thornton TA, Ananth CV, Williams M (2020). Maternal-fetal genetic interactions, imprinting, and risk of placental abruption. The journal of maternal-fetal & neonatal medicine, 1-10.
  20. Tekola-Ayele F, Workalemahu T, Amare A (2018). High burden of birthweight-lowering genetic variants in Africans and Asians. BMC medicine, 16(1), 70.
  21. Tekola-Ayele F, Workalemahu T, Amare A (2018). High burden of birthweight-lowering genetic variants in Africans and Asians. BMC medicine, 16(1), 70.
  22. Tekola-Ayele F, Lee A, Workalemahu T, Sánchez-Pozos (2019). Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases. Human genomics, 13(1), 17.
  23. Hübel C, Gaspar HA, Coleman JRI, Finucane H, Purves KL, Hanscombe KB, Prokopenko I, MAGIC investigators., Graff M, Ngwa JS, Workalemahu T, Eating Disorders Working Group of the Psychiatric Genomics Consortium., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., Schizophrenia Working Group of the Psychiatric Genomics Consortium., Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium., O'Reilly PF, Bulik CM, Breen (2018). Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. American journal of medical genetics. Part B, Neuropsychiatric genetics,
  24. Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu (2017). Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS genetics, 13(4), e1006528.
  25. Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu (2013). Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS genetics, 9(6), e1003500.
  26. Winkler TW, Day FR, Croteau-Chonka DC, Wood AR, Locke AE, Mägi R, Ferreira T, Fall T, Graff M, Justice AE, Luan J, Gustafsson S, Randall JC, Vedantam S, Workalemahu T, Kilpeläinen TO, Scherag A, Esko T, Kutalik Z, Heid IM, Loos RJ, Genetic Investigation of Anthropometric Traits (GIANT) Consortium (2014). Quality control and conduct of genome-wide association meta-analyses. Nature protocols, 9(5), 1192-212.
  27. He M, Workalemahu T, Manson JE, Hu FB, Qi (2012). Genetic determinants for body iron store and type 2 diabetes risk in US men and women. PloS one, 7(7), e40919.
  28. Shrestha D, Workalemahu T, Tekola-Ayele (2019). Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta. Epigenetics, 1-10.
  29. Workalemahu T, Enquobahrie DA, Moore A, Sanchez SE, Ananth CV, Pacora PN, Liang L, Salazar M, Williams M (2013). Genome-wide and candidate gene association studies of placental abruption. International journal of molecular epidemiology and genetics, 4(3), 128-39.
  30. Shrestha D, Rahman ML, Workalemahu T, Zhu C, Tekola-Ayele (2018). Influence of Fetal and Maternal Genetic Susceptibility to Obesity on Birthweight in African Ancestry Populations. Frontiers in genetics, 9, 511.
  31. Tekola-Ayele F, Lee A, Workalemahu T, Zhang W, Shrestha D, Amare AT, Ouidir (2019). Genetic overlap between birthweight and adult cardiometabolic diseases has implications for genomic medicine. Scientific reports, 9(1), 4076.
  32. Workalemahu T, Grantz KL, Grewal J, Zhang C, Louis GMB, Tekola-Ayele (2018). Genetic and Environmental Influences on Fetal Growth Vary during Sensitive Periods in Pregnancy. Scientific reports, 8(1), 7274.
  33. Riches NO, Workalemahu T, Johnson EP, Silver RM, Lopez S, Page J, Sartori B, Rothwell (2023). Creating a postmortem examination decision aid: Suggestions from bereaved parents of a stillborn. Patient education and counseling, 112, 107746.
  34. Dalton SE, Workalemahu T, Allshouse AA, Page JM, Reddy UM, Saade GR, Pinar H, Goldenberg RL, Dudley DJ, Silver R (2023). Copy number variants and fetal growth in stillbirths. American journal of obstetrics and gynecology, 228(5), 579.e1-579.e11.
  35. Workalemahu T, Page JM, Meeks H, Yu Z, Guinto E, Fraser A, Varner MW, Theilen LH, Quinlan A, Coon H, Enquobahrie DA, Ananth CV, Tekola-Ayele F, Jorde LB, Silver R (2023). Familial aggregation of stillbirth: A pedigree analysis of a matched case-control study. BJOG, 130(5), 454-462.
  36. Workalemahu T, Avery C, Lopez S, Blue NR, Wallace A, Quinlan AR, Coon H, Warner D, Varner MW, Branch DW, Jorde LB, Silver R (2023). Whole-genome sequencing analysis in families with recurrent pregnancy loss: A pilot study. PloS one, 18(2), e0281934.
  37. Workalemahu T, Dalton S, Allshouse A, Carey AZ, Page JM, Blue NR, Thorsten V, Goldenberg RL, Pinar H, Reddy UM, Silver R (2022). Copy number variants and placental abnormalities in stillborn fetuses: A secondary analysis of the Stillbirth Collaborative Research Network study. BJOG, 129(13), 2125-2131.
  38. Tekola-Ayele F, Zeng X, Chatterjee S, Ouidir M, Lesseur C, Hao K, Chen J, Tesfaye M, Marsit CJ, Workalemahu T, Wapner (2022). Placental multi-omics integration identifies candidate functional genes for birthweight. Nature communications, 13(1), 2384.
  39. Liu Z, Szpiro AA, Workalemahu T, Young MT, Kaufman JD, Enquobahrie D (2022). Associations of perinatal exposure to PM(2.5) with gestational weight gain and offspring birth weight. Environmental research, 204(Pt B), 112087.
  40. Workalemahu T, Rahman ML, Ouidir M, Wu J, Zhang C, Tekola-Ayele (2022). Associations of maternal blood pressure-raising polygenic risk scores with fetal weight. Journal of human hypertension, 36(1), 69-76.
  41. Tekola-Ayele F, Ouidir M, Shrestha D, Workalemahu T, Rahman ML, Mendola P, Grantz KL, Hinkle SN, Wu J, Zhang (2021). Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth. Human genetics, 140(7), 985-997.
  42. Workalemahu T, Shrestha D, Tajuddin SM, Tekola-Ayele (2021). Maternal cardiometabolic factors and genetic ancestry influence epigenetic aging of the placenta. Journal of developmental origins of health and disease, 12(1), 34-41.
  43. Carey AZ, Blue NR, Varner MW, Page JM, Chaiyakunapruk N, Quinlan AR, Branch DW, Silver RM, Workalemahu (2021). A systematic review to guide future efforts in the determination of genetic causes of pregnancy loss. Frontiers in reproductive health, 3,
  44. Tekola-Ayele F, Zeng X, Ouidir M, Workalemahu T, Zhang C, Delahaye F, Wapner (2020). DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases. Clinical epigenetics, 12(1), 78.
  45. Ouidir M, Zeng X, Workalemahu T, Shrestha D, Grantz KL, Mendola P, Zhang C, Tekola-Ayele (2020). Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases. Epigenomics, 12(11), 921-934.
  46. Shrestha D, Ouidir M, Workalemahu T, Zeng X, Tekola-Ayele (2020). Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain. International journal of obesity (2005), 44(6), 1406-1416.
  47. Tekola-Ayele F, Zhang C, Wu J, Grantz KL, Rahman ML, Shrestha D, Ouidir M, Workalemahu T, Tsai M (2020). Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy. PLoS genetics, 16(5), e1008747.
  48. Workalemahu T, Ouidir M, Shrestha D, Wu J, Grantz KL, Tekola-Ayele (2020). Differential DNA Methylation in Placenta Associated With Maternal Blood Pressure During Pregnancy. Hypertension (Dallas, Tex., 75(4), 1117-1124.
  49. Hübel C, Gaspar HA, Coleman JRI, Hanscombe KB, Purves K, Prokopenko I, Graff M, Ngwa JS, Workalemahu T, ADHD Working Group of the Psychiatric Genomics Consortium, Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC), Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, PTSD Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, International Headache Genetics Consortium, O'Reilly PF, Bulik CM, Breen (2019). Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent. Nature communications, 10(1), 5765.
  50. Ouidir M, Mendola P, Workalemahu T, Grewal J, Grantz KL, Zhang C, Wu J, Tekola-Ayele (2019). Race-ethnic differences in the associations of maternal lipid trait genetic risk scores with longitudinal fetal growth. Journal of clinical lipidology, 13(5), 821-831.
  51. Tekola-Ayele F, Workalemahu T, Gorfu G, Shrestha D, Tycko B, Wapner R, Zhang C, Louis GM (2019). Sex differences in the associations of placental epigenetic aging with fetal growth. Aging, 11(15), 5412-5432.
  52. Shrestha D, Rahman ML, Hinkle SN, Workalemahu T, Tekola-Ayele (2019). Maternal BMI-Increasing Genetic Risk Score and Fetal Weights among Diverse US Ethnic Groups. Obesity (Silver Spring, Md.), 27(7), 1150-1160.
  53. Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson A, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, den Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Grässler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jørgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, König IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaløy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimäki T, Lettre G, Liu J, Lokki ML, Lorentzon M, Luben RN, Ludwig B, MAGIC, Manunta P, Marek D, Marre M, Martin NG, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O'Rahilly S, Ong KK, Oostra B, Paré G, Parker AN, Perola M, Pichler I, Pietiläinen KH, Platou CG, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstråle M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Surakka I, Swift AJ, Tammesoo ML, Tardif JC, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tönjes A, Tuomi T, van Meurs JB, van Ommen GJ, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CI, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widen E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kähönen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Grönberg H, Gyllensten U, Hall P, Hansen T, Harris TB, Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Jarvelin MR, Kaprio J, Karpe F, Khaw KT, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, Peters A, Pramstaller PP, Quertermous T, Reinehr T, Rissanen A, Rudan I, Samani NJ, Schwarz PE, Shuldiner AR, Spector TD, Tuomilehto J, Uda M, Uitterlinden A, Valle TT, Wabitsch M, Waeber G, Wareham NJ, Watkins H, Procardis Consortium, Wilson JF, Wright AF, Zillikens MC, Chatterjee N, McCarroll SA, P (2010). Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature genetics, 42(11), 937-48.
  54. Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Lango Allen H, Weyant RJ, Wheeler E, Wood AR, MAGIC, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJ, Gjesing AP, Grallert H, Grässler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK, Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML, Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Paré G, Parker AN, Peden JF, Pichler I, Pietiläinen KH, Platou CG, Pouta A, Ridderstråle M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ, Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JB, van Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters GB, Widen E, Wild SH, Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kähönen M, Lehtimäki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll M, Tönjes A, Viikari J, Balkau B, Ben-Shlomo Y, Bergman RN, Boeing H, Smith GD, Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jørgensen T, Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A, Midthjell K, Pedersen O, Salomaa V, Schwarz PE, Tuomi T, Tuomilehto J, Valle TT, Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI, Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A, Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Jarvelin MR, Kao WH, Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM, Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo N, Spector TD, Syvanen AC, Uda M, Uitterlinden A, Völzke H, Vollenweider P, Wilson JF, Witteman JC, Wright AF, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, Frayling TM, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, North KE, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, Hirschhorn JN, Assimes TL, Wichmann HE, Thorsteinsdottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJ, Barroso I, McCarthy MI, Fox CS, Mohlke KL, Lindgren C (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature genetics, 42(11), 949-60.
  55. Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn J (2010). Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature, 467(7317), 832-8.

Review

  1. Veettil SK, Kategeaw W, Hejazi A, Workalemahu T, Rothwell E, Silver RM, Chaiyakunapruk (2023). The economic burden associated with stillbirth: A systematic review. Birth (Berkeley, Calif.), 50(2), 300-309.

Letter

  1. He MA, Workalemahu T, Cornelis MC, Hu FB, Qi (2011). Genetic variants near the IRS1 gene, physical activity and type 2 diabetes in US men and women. Diabetologia, 54(6), 1579-82.
  2. Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu (2017). Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS genetics, 13(8), e1006972.