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Ademuyiwa S. Aromolaran, FAHA, FHRS, PhD

Languages spoken: English

Academic Information

Departments: Surgery - Associate Professor, Biochemistry - Adjunct Associate Professor, Nutrition and Integrative Physiology - Adjunct Associate Professor

Divisions: Cardiothoracic Surgery

Academic Office Information

Education History

Graduate Training Massachusetts College of Pharmacy and Health Sciences
Regulatory Affairs
Graduate Certificate
Research Fellow Loyola University Medical Center
Research Fellow
Research Fellow Loyola University Medical Center
Research Fellow
Doctoral Training St George's, University of London
Graduate Training King's College London
Undergraduate University of Ibadan

Selected Publications

  1. Bernardi J, Aromolaran KA, Zhu H, Aromolaran AS (2021). Circadian Mechanisms: Cardiac Ion Channel Remodeling and Arrhythmias. Front Physiol, 11, 611860.
  2. Bernardi J, Aromolaran KA, Aromolaran AS (2020). Neurological Disorders and Risk of Arrhythmia. Int J Mol Sci, 22(1).
  3. Aromolaran AS (2019). Mechanisms of electrical remodeling in lipotoxic guinea pig heart. Biochem Biophys Res Commun, 519(3), 639-644.
  4. Martinez-Mateu L, Saiz J, Aromolaran AS (2019). Differential Modulation of IK and ICa,L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria. Front Physiol, 10, 1212.
  5. Morrow JP, Akar FG, Aromolaran AS (2019). Editorial: Arrhythmogenic Substrates in Diabetes and Obesity. Front Physiol, 10, 549.
  6. Boutjdir M, Aromolaran AS, de Las Fuentes L, Boyington JEA, Arteaga SS, Jobe J, Jeffe DB, Rao DC, Rice TK, Davila-Roman VG (2018). Research Education and Mentoring Program in Cardiovascular Diseases for Under-Represented Junior Faculty From NHLBI SIPID/PRIDE. J Am Coll Cardiol, 73(14), 1861-1865.
  7. Al A, Boutjdir M, Aromolaran AS (2019). Cardiolipotoxicity, Inflammation, and Arrhythmias: Role for Interleukin-6 Molecular Mechanisms. Front Physiol, 9, 1866.
  8. Aromolaran AS, Srivastava U, Al A, Chahine M, Lazaro D, El-Sherif N, Capecchi PL, Laghi-Pasini F, Lazzerini PE, Boutjdir M (2018). Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation. PLoS One, 13(12), e0208321.
  9. Aromolaran AS, Chahine M, Boutjdir M (2017). Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C. Handb Exp Pharmacol, 246, 161-184.
  10. Lazzerini PE, Laghi-Pasini F, Bertolozzi I, Morozzi G, Lorenzini S, Simpatico A, Selvi E, Bacarelli MR, Finizola F, Vanni F, Lazaro D, Aromolaran A, El Sherif N, Boutjdir M, Capecchi PL (2017). Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes. Heart, 103(22), 1821-1829.
  11. Aromolaran AS, Boutjdir M (2017). Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial Fibrillation. Front Physiol, 8, 431.
  12. Srivastava U, Aromolaran AS, Fabris F, Lazaro D, Kassotis J, Qu Y, Boutjdir M (2016). Novel function of α1D L-type calcium channel in the atria. Biochem Biophys Res Commun, 482(4), 771-776.
  13. Aromolaran AS, Colecraft HM, Boutjdir M (2016). High-fat diet-dependent modulation of the delayed rectifier K(+) current in adult guinea pig atrial myocytes. Biochem Biophys Res Commun, 474(3), 554-559.
  14. Puckerin A, Aromolaran KA, Chang DD, Zukin RS, Colecraft HM, Boutjdir M, Aromolaran AS (2016). hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms. Heart Rhythm, 13(5), 1121-1130.
  15. Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM (2014). LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms. Cardiovasc Res, 104(3), 501-11.
  16. Rong YP, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW (2009). The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc Natl Acad Sci U S A, 106(34), 14397-402.
  17. Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW (2007). Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol Cell, 31(2), 255-65.
  18. Aromolaran AS, Zima AV, Blatter LA (2007). Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. Am J Physiol Cell Physiol, 293(1), C106-18.
  19. Snopko RM, Aromolaran AS, Karko KL, Ramos-Franco J, Blatter LA, Meja-Alvarez R (2006). Cell culture modifies Ca2+ signaling during excitation-contraction coupling in neonate cardiac myocytes. Cell Calcium, 41(1), 13-25.
  20. Aromolaran AA, Blatter LA (2005). Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am J Physiol Cell Physiol, 289(6), C1426-36.
  21. Albert AP, Aromolaran AS, Large WA (2001). Agents that increase tyrosine phosphorylation activate a non-selective cation current in single rabbit portal vein smooth muscle cells. J Physiol, 530(Pt 2), 207-17.
  22. Aromolaran AS, Albert AP, Large WA (2000). Evidence for myosin light chain kinase mediating noradrenaline-evoked cation current in rabbit portal vein myocytes. J Physiol, 524 Pt 3, 853-63.
  23. Aromolaran AS, Large WA (1999). Comparison of the effects of divalent cations on the noradrenaline-evoked cation current in rabbit portal vein smooth muscle cells. J Physiol, 520 Pt 3, 771-82.