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Sara St. James, PhD, DABR

Languages spoken: English

Academic Information

Departments: Radiation Oncology - Associate Professor (Clinical)

Academic Office Information

Board Certification

  • American Board of Radiology (Therapeutic Medical Physics)

Education History

Certification Harvard Medical School
Medical Physics Residency
Doctoral Training University of California, Davis
Biomedical Engineering
Graduate Training McGill University
Medical Radiation Physics
Undergraduate Carleton University
Mathematics and Physics, High Honors

Selected Publications

  1. Sgouros G, Dewaraja YK, Escorcia F, Graves SA, Hope TA, Iravani A, Pandit-Taskar N, Saboury B, St James S, Zanzonico PB (2021). Tumor Response to Radiopharmaceutical Therapies: The Knowns and the Unknowns. J Nucl Med, 62(Suppl 3), 12S-22S.
  2. Capala J, Graves SA, Scott A, Sgouros G, St James S, Zanzonico P, Zimmerman BE (2021). Dosimetry for Radiopharmaceutical Therapy: Current Practices and Commercial Resources. J Nucl Med, 62(Suppl 3), 3S-11S.
  3. Laforest R, Khalighi M, Natsuaki Y, Rajagopal A, Chandramohan D, Byrd D, An H, Larson P, St James S, Sunderland JJ, Kinahan PE, Hope TA (2021). Harmonization of PET image reconstruction parameters in simultaneous PET/MRI. EJNMMI Phys, 8(1), 75.
  4. St James S, Bednarz B, Benedict S, Buchsbaum JC, Dewaraja Y, Frey E, Hobbs R, Grudzinski J, Roncali E, Sgouros G, Capala J, Xiao Y (2020). Current Status of Radiopharmaceutical Therapy. Int J Radiat Oncol Biol Phys, 109(4), 891-901.
  5. Xiao Y, Roncali E, Hobbs R, St James S, Bednarz B, Benedict S, Dewaraja YK, Frey E, Grudzinski J, Sgouros G, Buchsbaum JC, Capala J (2020). Toward Individualized Voxel-Level Dosimetry for Radiopharmaceutical Therapy. Int J Radiat Oncol Biol Phys, 109(4), 902-904.
  6. Tranel J, Feng FY, St James S, Hope TA (2021). Effect of microdistribution of alpha and beta-emitters in targeted radionuclide therapies on delivered absorbed dose in a GATE model of bone marrow. Phys Med Biol, 66(3), 035016.
  7. Roncali E, Capala J, Benedict SH, Akabani G, Bednarz B, Bhadrasain V, Bolch WE, Buchsbaum JC, Coleman NC, Dewaraja YK, Frey E, Ghaly M, Grudzinski J, Hobbs RF, Howell RW, Humm JL, Kunos CL, Larson S, Lin FI, Madsen M, Mirzadeh S, Morse D, Pryma D, Sgouros G, St James S, Wahl RW, Xiao Y, Zanzonico P, Zukotynski K (2021). Overview of the First NRG Oncology–National Cancer Institute Workshop on Dosimetry of Systemic Radiopharmaceutical Therapy. Journal of Nuclear Medicine, 62, 1133-1139.
  8. St James S, Grassberger C, Lu HM (2018). Considerations when treating lung cancer with passive scatter or active scanning proton therapy. Transl Lung Cancer Res, 7(2), 210-215.
  9. Tseng YD, Wootton L, Nyflot M, Apisarnthanarax S, Rengan R, Bloch C, Sandison G, St James S (2018). 4D computed tomography scans for conformal thoracic treatment planning: is a single scan sufficient to capture thoracic tumor motion? Phys Med Biol, 63(2), 02NT03.
  10. Saini J, Maes D, Egan A, Bowen SR, St James S, Janson M, Wong T, Bloch C (2017). Dosimetric evaluation of a commercial proton spot scanning Monte-Carlo dose algorithm: comparisons against measurements and simulations. Phys Med Biol, 62(19), 7659-7681.
  11. Saini J, Bowen SL, St James S, Wong T, Bloch CD (2017). Evaluation of ceramic marker for the treatment of ocular melanoma with proton therapy. Biomed Phys Eng Express, 3(2).
  12. Berman AT, St James S, Rengan R (2015). Proton Beam Therapy for Non-Small Cell Lung Cancer: Current Clinical Evidence and Future Directions. Cancers (Basel), 7(3), 1178-90.
  13. Koybasi O, Mishra P, St James S, Lewis JH, Seco J (2014). Simulation of dosimetric consequences of 4D-CT-based motion margin estimation for proton radiotherapy using patient tumor motion data. Phys Med Biol, 59(4), 853-67.
  14. St James S, Seco J, Mishra P, Lewis JH (2013). Simulations using patient data to evaluate systematic errors that may occur in 4D treatment planning: a proof of concept study. Med Phys, 40(9), 091706.
  15. Williams CL, Mishra P, Seco J, St James S, Mak RH, Berbeco RI, Lewis JH (2013). A mass-conserving 4D XCAT phantom for dose calculation and accumulation. Med Phys, 40(7), 071728.
  16. Mishra P, Li R, St James S, Mak RH, Williams CL, Yue Y, Berbeco RI, Lewis JH (2013). Evaluation of 3D fluoroscopic image generation from a single planar treatment image on patient data with a modified XCAT phantom. Phys Med Biol, 58(4), 841-58.
  17. Mishra P, St James S, Segars WP, Berbeco RI, Lewis JH (2012). Adaptation and applications of a realistic digital phantom based on patient lung tumor trajectories. Phys Med Biol, 57(11), 3597-608.
  18. St James S, Mishra P, Hacker F, Berbeco RI, Lewis JH (2012). Quantifying ITV instabilities arising from 4DCT: a simulation study using patient data. Phys Med Biol, 57(5), L1-7.
  19. Yang YSt James S, Wu Y, Du H, Qi J, Farrell R, Dokhale PA, Shah KS, Vaigneur K, Cherry SR (2010). Tapered LSO arrays for small animal PET. Phys Med Biol, 56(1), 139-53.
  20. St James S, Yang Y, Bowen SL, Qi J, Cherry SR (2009). Simulation study of spatial resolution and sensitivity for the tapered depth of interaction PET detectors for small animal imaging. Phys Med Biol, 55(2), N63-74.
  21. St James S, Yang Y, Wu Y, Farrell R, Dokhale P, Shah KS, Cherry SR (2009). Experimental characterization and system simulations of depth of interaction PET detectors using 0.5 mm and 0.7 mm LSO arrays. Phys Med Biol, 54(14), 4605-19.
  22. Yang Y, Qi J, Wu Y, St James S, Farrell R, Dokhale PA, Shah KS, Cherry SR (2008). Depth of interaction calibration for PET detectors with dual-ended readout by PSAPDs. Phys Med Biol, 54(2), 433-45.
  23. Yang Y, Wu Y, Qi J, St James S, Du H, Dokhale PA, Shah KS, Farrell R, Cherry SR (2008). A prototype PET scanner with DOI-encoding detectors. J Nucl Med, 49(7), 1132-40.
  24. St James S, Thompson CJ (2006). Image blurring due to light-sharing in PET block detectors. Med Phys, 33(2), 405-10.