Natalia Sara Harasymowicz

Natalia Sara Harasymowicz, PhD

Languages spoken: English

Academic Information

Departments Primary - Orthopaedics

Education History

Undergraduate Jagiellonian University
 SB
Graduate Training Jagiellonian University
 MSci
Doctoral Training University of Edinburgh
 PhD

Selected Publications

Journal Article

  1. Harasymowicz NS, Azfer A, Burnett R, Simpson H, Salter DM (2021). Chondrocytes from osteoarthritic cartilage of obese patients show altered adiponectin receptors expression and response to adiponectin. J Orthop Res, 39(11), 2333-2339.
  2. Harasymowicz NS, Rashidi N, Savadipour A, Wu CL, Tang R, Bramley J, Buchser W, Guilak F (2021). Single-cell RNA sequencing reveals the induction of novel myeloid and myeloid-associated cell populations in visceral fat with long-term obesity. FASEB J, 35(3), e21417.
  3. Choi YR, Collins KH, Springer LE, Pferdehirt L, Ross AK, Wu CL, Moutos FT, Harasymowicz NS, Brunger JM, Pham CTN, Guilak F (2021). A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery. Sci Adv, 7(36), eabj1414.
  4. Harasymowicz NS, Choi YR, Wu CL, Iannucci L, Tang R, Guilak F (2020). Intergenerational Transmission of Diet-Induced Obesity, Metabolic Imbalance, and Osteoarthritis in Mice. Arthritis Rheumatol, 72(4), 632-644.
  5. Oestreich AK, Collins KH, Harasymowicz NS, Wu CL, Guilak F (2020). Is Obesity a Disease of Stem Cells? Cell Stem Cell, 27(1), 15-18.
  6. Tang R, Harasymowicz NS, Wu CL, Collins KH, Choi YR, Oswald SJ, Guilak F (2020). Gene therapy for follistatin mitigates systemic metabolic inflammation and post-traumatic arthritis in high-fat diet-induced obesity. Sci Adv, 6(19), eaaz7492.
  7. Votava L, Schwartz AG, Harasymowicz NS, Wu CL, Guilak F (2019). Effects of dietary fatty acid content on humeral cartilage and bone structure in a mouse model of diet-induced obesity. J Orthop Res, 37(3), 779-788.
  8. Thompson MD, Derse A, Ferey J, Reid M, Xie Y, Christ M, Chatterjee D, Nguyen C, Harasymowicz N, Guilak F, Moley KH, Davidson NO (2019). Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease. Am J Physiol Endocrinol Metab, 316(4), E674-E686.
  9. Harasymowicz NS, Clement ND, Azfer A, Burnett R, Salter DM, Simpson AHWR (2017). Regional Differences Between Perisynovial and Infrapatellar Adipose Tissue Depots and Their Response to Class II and Class III Obesity in Patients With Osteoarthritis. Arthritis Rheumatol, 69(7), 1396-1406.

Review

  1. Klimak M, Nims RJ, Pferdehirt L, Collins KH, Harasymowicz NS, Oswald SJ, Setton LA, Guilak F (2021). Immunoengineering the next generation of arthritis therapies. [Review]. Acta Biomater, 133, 74-86.
  2. Wu CL, Harasymowicz NS, Klimak MA, Collins KH, Guilak F (2020). The role of macrophages in osteoarthritis and cartilage repair. [Review]. Osteoarthritis Cartilage, 28, (5), 544-554.
  3. Harasymowicz NS, Dicks A, Wu CL, Guilak F (2019). Physiologic and pathologic effects of dietary free fatty acids on cells of the joint. [Review]. Ann N Y Acad Sci, 1440, (1), 36-53.

Letter

  1. Harasymowicz NS, Clement ND, Burnett R, Azfer A, Salter DM, Simpson AHWR (2018). Reply. [Letter to the editor]. Arthritis Rheumatol, 70(1), 147-148.