The Roy Laboratory is focused on understanding how different retinal cell types work in concert to generate vision and how vision is impaired in diseases such as glaucoma and diabetic retinopathy. The lab uses a multidisciplinary and comparative approach to study the organization and function of neural circuits in the retina, retinal projections to the brain, and structural and functional anomalies within the retina in blinding diseases. The knowledge gained from these studies is used to identify molecular and neural targets for vision restorative therapies.
The lab is also developing novel imaging, computational, and virus-based gene delivery techniques for retinal research.
Before joining the John A. Moran Eye Center at the University of Utah, Dr. Roy completed a postdoctoral fellowship at the Duke University School of Medicine and worked as a senior research associate at Duke and as an assistant project scientist at the Stein Eye Institute at the University of California at Los Angeles.
Education History
| Doctoral Training |
Indiana University Bloomington |
PhD |
|---|
Selected Publications
Journal Article
- Roy S, Yao X, Rathinavelu J, Field GD (2024). GABAergic Inhibition Controls Receptive Field Size, Sensitivity, and Contrast Preference of Direction Selective Retinal Ganglion Cells Near the Threshold of Vision. J Neurosci, 44(11). (Read full article)
- Roy S, Wang D, Rudzite AM, Perry B, Scalabrino ML, Thapa M, Gong Y, Sher A, Field GD (2023). Large-scale interrogation of retinal cell functions by 1-photon light-sheet microscopy. Cell Rep Methods, 3(4), 100453. (Read full article)
- Roy S, Field GD (2022). An optical approach for mapping functional connectivity at single-cell resolution in brain circuits. Cell Rep Methods, 2(8), 100272. (Read full article)
- Wang D, Roy S, Rudzite AM, Field GD, Gong Y (2021). High-resolution light-field microscopy with patterned illumination. Biomed Opt Express, 12(7), 3887-3901. (Read full article)
- Roy S, Jun NY, Davis EL, Pearson J, Field GD (2021). Inter-mosaic coordination of retinal receptive fields. Nature, 592(7854), 409-413. (Read full article)