Somayeh Gholami

Somayeh Gholami, PhD, DABR

Languages spoken: English

Academic Information

Departments Primary - Radiation Oncology

Somayeh Gholami, M.S., Ph.D., is an Assistant Professor at the University of Utah School of Medicine and a Medical Physicist in the Department of Radiation Oncology at Huntsman Cancer Hospital (HCH). Dr. Gholami earned her M.Sc. in Radiation Medicine Engineering from Shahid Beheshti University and completed her Ph.D. in Medical Physics at Tehran University of Medical Sciences (TUMS) in Iran. She completed her residency training in Medical Physics at the University of Arkansas for Medical Sciences (UAMS). Her clinical and research interests include Monte Carlo simulations for radiotherapy, brachytherapy, spatially fractionated radiation therapy (SFRT), stereotactic radiosurgery (SRS), radiobiological modeling, and advancements in cancer treatment.

Education History

Undergraduate Tarbiat Moallem University of Tehran
 BS
Graduate Training Shahid Behesti University
 MSc
Graduate Training Tehran University of Medical Sciences
 PhD
Postdoctoral Fellowship Virginia Commonwealth University
 Postdoctoral Fellow
Residency University of Arkansas for Medical Sciences
 Resident

Selected Publications

Journal Article

  1. Aloraibi HA, Siavashpour Z, Ghorbani M, Abtahi M, Jassim H, Gholami S (2023). Evaluating dose distributions of high dose rate (60)Co brachytherapy in an asymmetric tumor: A comparison of different designs of vaginal cylindrical applicators.(Epub ahead of print) Appl Radiat Isot, 204, 111124.
  2. Shoorche AB, Mohammadkarim A, Jadidi M, Bahraminasab M, Bagheri H, Gholami S (2023). Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation. J Cancer Res Ther, 19(5), 1311-1315.
  3. Gebremariam TY, Geraily G, Jassim HH, Gholami S (2023). Dosimetric comparison between microSelectron iridium-192 and flexi cobalt-60 sources in high-dose-rate brachytherapy using Geant4 Monte Carlo code. J Contemp Brachytherapy, 15(2), 141-147.
  4. Sadeghi S, Farzin M, Gholami S (2023). Fully automated clinical target volume segmentation for glioblastoma radiotherapy using a deep convolutional neural network. Pol J Radiol, 88, e31-e40.
  5. Shahzadeh S, Barough MS, Ganjoorian H, Gholami S (2022). Comparison of normal tissue doses in deep inspiration breath-hold and free breathing methods for radiotherapy of left-sided breast cancer using 4D-XCAT digital phantom. J Cancer Res Ther, 18(Supplement), S335-S340.
  6. Abtahi M, Safaei AM, Sheikhzade P, Gholami S (2022). A Dosimetric evaluation of a high dose rate cobalt-60 brachytherapy source using shielded, single and multi-channel cylinder applicators for gynecological cancers. Med Dosim, 47(4), 318-324.
  7. Sohn JJ, Polizzi M, Richeson D, Gholami S, Das IJ, Song WY (2022). A Novel Workflow with a Customizable 3D Printed Vaginal Template and a Direction Modulated Brachytherapy (DMBT) Tandem Applicator for Adaptive Interstitial Brachytherapy of the Cervix. J Clin Med, 11(23).
  8. Jafarzadeh N, Hejazi P, Tajik Mansoury MA, Khodabakhshi R, Riazi Z, Gholami (2022). Investigation the effect of a magnetic field on the dose distribution of I-125, Ir-192, Yb-169, and Co-60 brachytherapy sources by Monte Carlo simulation. Applied radiation and isotopes, 187, 110332.
  9. Pakniyat F, Nedaie HA, Mozdarani H, Mahmoudzadeh A, Gholami (2022). Evaluation of Capability and Relationship of Different Radiobiological Endpoints for Radiosensitivity Prediction in Human Tumor Cell Lines Compared with Clonogenic Survival. Journal of biomedical physics & engineering, 12(2), 127-136.
  10. Tegaw EM, Geraily G, Gholami S, Shojaei M, Tadesse G (2022). Gold-nanoparticle-enriched breast tissue in breast cancer treatment using the INTRABEAM® system: a Monte Carlo study. Radiation and environmental biophysics, 61(1), 119-131.
  11. Abtahi M, Gholami S, Jassim H (2021). High dose rate(192)Ir versus high dose rate(60)Co brachytherapy: an overview of systematic reviews of clinical responses of gynecological cancers from 1984 to 2020. Biomedical physics & engineering express, 7(5),
  12. Sadeghi S, Siavashpour Z, Vafaei Sadr A, Farzin M, Sharp R, Gholami (2021). A rapid review of influential factors and appraised solutions on organ delineation uncertainties reduction in radiotherapy. Biomedical physics & engineering express, 7(5),
  13. Tegaw EM, Geraily G, Etesami SM, Ghanbari H, Gholami S, Shojaei M, Farzin M, Tadesse G (2021). Dosimetric effect of nanoparticles in the breast cancer treatment using INTRABEAM(®)system with spherical applicators in the presence of tissue heterogeneities: A Monte Carlo study. Biomedical physics & engineering express, 7(3),
  14. Alyani Nezhad Z, Geraily G, Hataminia F, Parwaie W, Ghanbari H, Gholami (2021). Bismuth oxide nanoparticles as agents of radiation dose enhancement in intraoperative radiotherapy. Medical physics, 48(3), 1417-1426.
  15. Tegaw EM, Geraily G, Etesami SM, Gholami S, Ghanbari H, Farzin M, Tadesse GF, Shojaei (2021). A Comparison between Electron Gamma Shower, National Research Council/Easy Particle Propagation (EGSnrc/Epp) and Monte Carlo N-Particle Transport Code (MCNP) in Simulation of the INTRABEAM ® System with Spherical Applicators. Journal of biomedical physics & engineering, 11(1), 47-54.
  16. Pakniyat F, Mozdarani H, Nedaie HA, Mahmoudzadeh A, Salimi M, Gholami (2023). Bystander Response Following High-Dose X-irradiation; Time-dependent Nature of GammaH2AX Foci and Cell Death Consequences. Journal of biomedical physics & engineering, 13(1), 17-28.
  17. Nedaie HA, Gholami S, Longo F, Banaee N, Hassani M, Sarfehnia A, Pang (2020). The effect of magnetic field on Linac based Stereotactic Radiosurgery dosimetric parameters. Biomedical physics & engineering express, 7(1),
  18. Kavousi N, Nedaie HA, Gholami S, Esfahani M, Shafiekhani S, Hassani (2020). Ipsilateral lung normal tissue complication probability parameters for different dose calculation algorithms in radiotherapy of breast cancer. Journal of cancer research and therapeutics, 16(6), 1323-1330.
  19. Pakniyat F, Nedaie HA, Mozdarani H, Mahmoudzadeh A, Salimi M, Griffin RJ, Gholami (2020). Enhanced response of radioresistant carcinoma cell line to heterogeneous dose distribution of grid; the role of high-dose bystander effect. International journal of radiation biology, 96(12), 1585-1596.
  20. Omyan G, Gholami S, Zad AG, Severgnini M, Longo F, Kalantari (2020). Monte Carlo simulation and analytical calculation methods to investigate the potential of nanoparticles for INTRABEAM® IORT machine. Nanomedicine, 30, 102288.
  21. Shahzadeh S, Gholami S, Aghamiri SMR, Mahani H, Nabavi (2020). Evaluation of the organs at risk doses for lung tumors in gated and conventional radiotherapy. Journal of cancer research and therapeutics, 16(4), 726-730.
  22. Gholami S, Longo F, Shahzadeh S, Nedaie HA, Sharp R, S Meigooni (2020). Normal lung tissue complication probability in MR-Linac and conventional radiotherapy. Reports of practical oncology and radiotherapy, 25(6), 961-968.
  23. Tegaw EM, Gholami S, Omyan G, Geraily (2020). Dosimetric characteristics of the INTRABEAM ® system with spherical applicators in the presence of air gaps and tissue heterogeneities. Radiation and environmental biophysics, 59(2), 295-306.
  24. Ranjbar S, Gholami S, Longo F, Sharp R, Meigooni A (2020). Impact of magnetic fields on calculated AAPM TG-43 parameters for (192)Ir and (60)Co HDR brachytherapy sources: A Monte Carlo study. Applied radiation and isotopes, 159, 109088.
  25. Gholami S, Longo F, Nedaie HA, Berti A, Mousavi M, Meigooni A (2018). Application of Geant4 Monte Carlo simulation in dose calculations for small radiosurgical fields. Medical dosimetry, 43(3), 214-223.
  26. Shahzadeh S, Gholami S, Aghamiri SMR, Mahani H, Nabavi M, Kalantari (2018). Evaluation of normal lung tissue complication probability in gated and conventional radiotherapy using the 4D XCAT digital phantom. Computers in biology and medicine, 97, 21-29.
  27. Gholami S, Nedaie HA, Longo F, Ay MR, Dini SA, Meigooni A (2017). Grid Block Design Based on Monte Carlo Simulated Dosimetry, the Linear Quadratic and Hug-Kellerer Radiobiological Models. Journal of medical physics, 42(4), 213-221.
  28. Gholami S, Mirzaei HR, Jabbary Arfaee A, Jaberi R, Nedaie HA, Rabi Mahdavi S, Rajab Bolookat E, Meigooni A (2016). Dose distribution verification for GYN brachytherapy using EBT Gafchromic film and TG-43 calculation. Reports of practical oncology and radiotherapy, 21(5), 480-6.
  29. Gholami S, Nedaie HA, Longo F, Ay MR, Wright S, Meigooni A (2016). Is grid therapy useful for all tumors and every grid block design?. Journal of applied clinical medical physics, 17(2), 206-219.
  30. Farhan F, Fazeli MS, Samiei F, Aghili M, Haddad P, Gholami S, Nabavi (2015). Morbidity and Mortality Following Short Course Preoperative Radiotherapy in Rectal Carcinoma. Acta medica Iranica, 53(10), 627-32.
  31. Asnaashari K, Nodehi MR, Mahdavi SR, Gholami S, Khosravi H (2013). Dosimetric comparison of different inhomogeneity correction algorithms for external photon beam dose calculations. Journal of medical physics, 38(2), 74-81.
  32. Payandeh M, Sadeghi M, Richeson D, Gholami (2022). Determination of TG-43 dosimetric parameters for I-125, Ir-192 and Co-60 brachytherapy sources using the Monte Carlo simulation. Radiation Physics & Engineering, 3(4), 7-15.
  33. Farzin M, Garosi M, Rajabpour MV, Gholami (2022). Deep inspiration breath hold (DIBH) for cardiac sparing in breast cancer radiotherapy. International Journal of Radiation Research, 20(1), 91-95.
  34. Tajiki S, Gholami S, et a (2021). Management of bulky high-grade pleomorphic sarcoma using grid therapy technique. International Journal of Radiation Research, 19(1),
  35. Pakniyat F, Nedaie HA, Mozdarani H, Mahmoudzadeh A, Gholami (2022). Evaluation of Capability and Relationship of Different Radiobiological Endpoints for Radiosensitivity Prediction in Human Tumor Cell Lines Compared with Clonogenic Survival. Journal of biomedical physics & engineering, 12(2), 127-136.
  36. Tajiki S, Gholami S, Esfahani M, Rastjoo A, Hakimi A, Beheshti AK, Meigooni (2020). Photon and photon–neutron experimental dosimetry in Grid therapy with 18 MV photon beams. Journal of radiotherapy in practice, 20(4), 1-7.
  37. Pakniyat F, Gholami S, Nedaie HA, et a (2020). Demonstration of Bystander Response in High Dose Technique of Grid Using Theoretical Calculation by Linear Quadratic Model Along with Experimental Investigations. International Journal of Radiation Research, 18(3), 495-504.
  38. Nezhad ZA, Geraily G, Hataminia F, Gholami S, Abtahi SMM, Ghanbari (2020). Investigation of the dose enhancement effect of spherical bismuth oxide nanoparticles in external beam radiotherapy. Nanomedicine Research Journal, 5(1), 55-62.
  39. Shahzadeh S, Gholami S, Aghamiri SMR, Mahani H, Nabavi (2020). Evaluation of the organs at risk doses for lung tumors in gated and conventional radiotherapy. Journal of cancer research and therapeutics, 16(4), 726-730.
  40. Elham H, Ghazale G, Mahbod E, Mostafa F, Gholami (2021). Comparison of calculated and measured basic dosimetric parameters for total body irradiation with 6-MV and 18-MV photon beams. Journal of radiotherapy in practice, 20(1), 66-70.
  41. Marvi M, Gholami S, Barough MS, Hosseini M, Nabavi M, Jabery (2021). Evaluation of exit skin dose for intra-cavitary brachytherapy treatments by the BEBIG 60Co machine using thermo-luminescent dosimeters. Journal of radiotherapy in practice, 20(1), 49-54.
  42. Dallal ZT, Gholami S, Barough M (2021). Fabrication and Validation of Respiratory Control Belt Using Load Cell Sensor. Frontiers in Biomedical Technologies, 7(4), 281-285.
  43. Rooshenas A, Gholami S, Barough MS, Mohammadi (2018). Dosimetric Accuracy Comparison between ACUROSE XB, AAA and PBC Dose Calculation Algorithms in Eclipse TPS Using a Heterogeneous Phantom. Frontiers in Biomedical Technologies, 6(4), 168-173.
  44. Kavousi N, Nedaie HA, Gholami S, Esfahani M, Geraily (2019). Evaluation of dose calculation algorithms accuracy for eclipse, PCRT3D, and monaco treatment planning systems using IAEA TPS commissioning tests in a Heterogeneous Phantom. Iranian Journal of Medical Physics, 16(4), 285-293.
  45. Gholami S, Nedaie HA, Meigooni A (2019). Precise EBT3 Gafchromic film dosimetry for Grid therapy. Radiation Measurements, 121, 69-76.
  46. Gholami S, Mirzaei HR, Arfaee AJ, Jaberi R, Nedaie HA, Mahdavi SR, Bolookat ER, Meigooni A (2016). A novel phantom design for brachytherapy quality assurance. International Journal of Radiation Research, 14(1), 67-71.
  47. Asnaashari K, Gholami S, Khosravi H (2014). Lessons learnt from errors in radiotherapy centers. International Journal of Radiation Research, 12(4), 361-367.
  48. Gholami S, Asl AK, Aghamiri SM, Allahverdi (2010). Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data. Iranian Journal of Medical Physics, 7(2), 57-63.
  49. Gautam S, Osman AFI, Richeson D, Gholami S, Manandhar B, Alam S, Song W (2024). Attention 3D U-NET for dose distribution prediction of high-dose-rate brachytherapy of cervical cancer: Direction modulated brachytherapy tandem applicator. Medical physics,
  50. Salamat, Fatemeh and Siavashpour, Zahra and Sadeghi, Mahdi and Jaberi, Ramin and Gholami, Somaye Dosimetric evaluation and Monte Carlo simulation of a new proposed surface brachytherapy mould. 16(4), 279--288.
  51. Gebremariam T, Geraily G, Longo F, Gholami (2025). Radiation dose escalation by injecting bismuth, gold and platinum nanoparticles into a tumour during high dose rate (192)Ir brachytherapy: a Monte Carlo study. Radiation and environmental biophysics,
  52. Salamat F, Siavashpour Z, Sadeghi M, Jaberi R, Gholami (2024). Dosimetric evaluation and Monte Carlo simulation of a new proposed surface brachytherapy mould. Journal of contemporary brachytherapy, 16(4), 279-288.
  53. Gautam S, Osman AFI, Richeson D, Gholami S, Manandhar B, Alam S, Song W (2025). Attention 3D UNET for dose distribution prediction of high-dose-rate brachytherapy of cervical cancer: Intracavitary applicators. Journal of applied clinical medical physics, 26(2), e14568.
  54. Yousefi A, Ketabi S, Moreno AC, Abedi I, Kim Y, Gholami (2025). An innovative process for efficient automated optimizing IMRT knowledge-based planning (KBP). Medical physics, 52(9), e18055.
  55. Richeson, Dylan and Gholami, Somayeh and Manandhar, Binod and Alam, Sharmin and Gautam, Suman and Sohn, James J. and Scanderbeg, Daniel and Yashar, Catheryn and Prisciandaro, Joann and Jolly, Shruti and Fields, Emma and Beriwal, Sushil and Song, William Y Multi-institutional evaluation of direction-modulated brachytherapy tandems for cervical cancer. 2(4),
  56. Megahed, Romy J and Lewis, Gary D and Gholami, Somayeh and Wurtz, April and Samanta, Santanu and Patel, Mausa Liver-Sparing Total Body Irradiation Using Helical Tomotherapy for Relapsed Pre-B-cell Acute Lymphoblastic Leukemia. 17(12),

Review

  1. Tajiki S, Joya M, Gharekhani V, Richeson D, Gholami S (2023). A systematic review of the normal tissue complication probability models and parameters: Head and neck cancers treated with conformal radiotherapy. [Review]. Head Neck, 45, (12), 3146-3156.
  2. Omyan G, Musa AE, Shabeeb D, Akbardoost N, Gholami (2020). Efficacy and toxicity of FLASH radiotherapy: A systematic review. Journal of cancer research and therapeutics, 16(6), 1203-1209.
  3. Tajik M, Akhlaqi MM, Gholami (2022). Advances in anthropomorphic thorax phantoms for radiotherapy: a review. Biomedical physics & engineering express, 8(5),

Book

  1. Gholami S, Yazdani (2020). Principles of Shielding Calculations in Radiotherapy.