Aja Aravamudhan

Aja Aravamudhan, PhD, NRCC-CC

Languages spoken: English

Academic Information

Departments Primary - Pathology

Board Certification

  • American Board of Clinical Chemistry

Education History

Fellowship University of Minnesota
 Postdoctoral Fellow
Postdoctoral Fellowship Mayo Clinic
 Postdoctoral Research Fellow
Postdoctoral Training Yale University
 Postdoctoral Associate
Doctoral Training UConn Health, University of Connecticut School of Medicine
 PhD
Undergraduate Anna University
 BS

Selected Publications

Journal Article

  1. Aravamudhan A, Scalf C, Greenwood MP, Muluhngwi P (2025). The Effect of Clinical Decision Support Intervention on Monitoring for Donor Specific Antibodies. jfaf030. J Appl Lab Med. (Read full article)
  2. Aravamudhan A, Dieffenbach PB, Choi KM, Link PA, Meridew JA, Haak AJ, Fredenburgh LE, Tschumperlin DJ (2024). Non-canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells. Physiol Rep, 12(7), e15999. (Read full article)
  3. Gao AY, Diaz Espinosa AM, Gian F, Pham TX, Carver CM, Aravamudhan A, Bartman CM, Ligresti G, Caporarello N, Schafer MJ, Haak AJ (2022). Pim-1 kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome. Am J Physiol Lung Cell Mol Physiol, 323(6), L685-L697. (Read full article)
  4. Dieffenbach PB, Aravamudhan A, Fredenburgh LE, Tschumperlin DJ (2021). The Mechanobiology of Vascular Remodeling in the Aging Lung. Physiology (Bethesda), 37(1), 28-38. (Read full article)
  5. Choi KM, Haak AJ, Diaz Espinosa AM, Cummins KA, Link PA, Aravamudhan A, Wood DK, Tschumperlin DJ (2021). GPCR-mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7. J Cell Physiol, 236(11), 7759-7774. (Read full article)
  6. Caporarello N, Meridew JA, Aravamudhan A, Jones DL, Austin SA, Pham TX, Haak AJ, Moo Choi K, Tan Q, Haresi A, Huang SK, Katusic ZS, Tschumperlin DJ, Ligresti G (2020). Vascular dysfunction in aged mice contributes to persistent lung fibrosis. Aging Cell, 19(8), e13196. (Read full article)
  7. Aravamudhan A, Haak AJ, Choi KM, Meridew JA, Caporarello N, Jones DL, Tan Q, Ligresti G, Tschumperlin DJ (2020). TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation. Am J Physiol Lung Cell Mol Physiol, 318(5), L852-L863. (Read full article)
  8. Liu W, Meridew JA, Aravamudhan A, Ligresti G, Tschumperlin DJ, Tan Q (2019). Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression. Respir Res, 20(1), 281. (Read full article)
  9. Haak AJ, Kostallari E, Sicard D, Ligresti G, Choi KM, Caporarello N, Jones DL, Tan Q, Meridew J, Diaz Espinosa AM, Aravamudhan A, Maiers JL, Britt RD Jr, Roden AC, Pabelick CM, Prakash YS, Nouraie SM, Li X, Zhang Y, Kass DJ, Lagares D, Tager AM, Varelas X, Shah VH, Tschumperlin DJ (2018). Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis. Sci Transl Med, 11(516). (Read full article)
  10. Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ (2019). CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis. JCI Insight, 5(12). (Read full article)
  11. Manoukian OS, Aravamudhan A, Lee P, Arul MR, Yu X, Rudraiah S, Kumbar SG (2018). Spiral Layer-by-Layer Micro-Nanostructured Scaffolds for Bone Tissue Engineering. ACS Biomater Sci Eng, 4(6), 2181-2192. (Read full article)
  12. Aravamudhan A, Ramos DM, Nip J, Kalajzic I, Kumbar SG (2017). Micro-Nanostructures of Cellulose-Collagen for Critical Sized Bone Defect Healing. Macromol Biosci, 18(2). (Read full article)
  13. Aravamudhan A, Ramos DM, Nip J, Harmon MD, James R, Deng M, Laurencin CT, Yu X, Kumbar SG (2013). Cellulose and collagen derived micro-nano structured scaffolds for bone tissue engineering. J Biomed Nanotechnol, 9(4), 719-31. (Read full article)
  14. Aravamudhan A, Ramos DM, Nip J, Subramanian A, James R, Harmon MD, Yu X, Kumbar SG (2013). Osteoinductive small molecules: growth factor alternatives for bone tissue engineering. Curr Pharm Des, 19(19), 3420-8. (Read full article)
  15. Kumbar SG, Toti US, Deng M, James R, Laurencin CT, Aravamudhan A, Harmon M, Ramos DM (2011). Novel mechanically competent polysaccharide scaffolds for bone tissue engineering. Biomed Mater, 6(6), 065005. (Read full article)