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My N. Helms

My N. Helms, PhD

Languages spoken: English

Academic Information

Departments Primary - Internal Medicine


Academic Office Information

Education History

Postdoctoral Fellowship Emory University School of Medicine
Postdoctoral Fellow
Dartmouth Medical School
Postdoctoral Fellow
Postdoctoral Fellowship Emory University School of Medicine
Postdoctoral Fellow
Dartmouth Medical School
Undergraduate University of North Carolina at Chapel Hill

Selected Publications

Journal Article

  1. My N Helms, Camila Coca, Charles A Downs, and Wei Wu (Pending). Redox Sensitivities of δ- and α- epithelial sodium channel (ENaC) subunits. (Epub ahead of print) J Biol Chem.
  2. Garett J Grant, Robert Paine III, Theodore G Liou, and My N Helms (Pending). High Mobility Group Box-1 Increases Epithelial Sodium Channel Activity and Inflammation via the Receptor for Advanced Glycation End Products. (Epub ahead of print) Am J Physiol Lung Cell Mol Physiol.
  3. Patrice Mimche, Ethan Goh, Wei-Jun Qian, and My N Helms (Pending). Increased Epithelial Sodium Channel (ENaC) Activity Protects Preterm Lungs from Hyperoxia-Induced Lung Injury. (Epub ahead of print) Am J Physiol Lung Cell Mol Physiol.
  4. Warren KJ, Beck EM, Callahan SJ, Helms MN, Middleton E, Maddock S, Carr JR, Harris D, Blagev DP, Lanspa MJ, Brown SM, Paine R 3rd (2023). Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype. Respir Res, 24(1), 162.
  5. Zhang T, Day NJ, Gaffrey M, Weitz KK, Attah K, Mimche PN, Paine R 3rd, Qian WJ, Helms MN (2022). Regulation of hyperoxia-induced neonatal lung injury via post-translational cysteine redox modifications. Redox Biol, 55, 102405.
  6. Grant GJ, Mimche PN, Paine R 3rd, Liou TG, Qian WJ, Helms MN (2021). Enhanced epithelial sodium channel activity in neonatal Scnn1b mouse lung attenuates high oxygen-induced lung injury. Am J Physiol Lung Cell Mol Physiol, 321(1), L29-L41.
  7. Sturrock A, Zimmerman E, Helms M, Liou TG, Paine R 3rd (2021). Hypoxia induces expression of angiotensin-converting enzyme II in alveolar epithelial cells: Implications for the pathogenesis of acute lung injury in COVID-19. Physiol Rep, 9(9), e14854.
  8. Liou TG, Adler FR, Cahill BC, Cox DR, Cox JE, Grant GJ, Hanson KE, Hartsell SC, Hatton ND, Helms MN, Jensen JL, Kartsonaki C, Li Y, Leung DT, Marvin JE, Middleton EA, Osburn-Staker SM, Packer KA, Shakir SM, Sturrock AB, Tardif KD, Warren KJ, Waddoups LJ, Weaver LJ, Zimmerman E, Paine R 3rd (2020). SARS-CoV-2 innate effector associations and viral load in early nasopharyngeal infection. Physiol Rep, 9(4), e14761.
  9. Grant GJ, Liou TG, Paine R 3rd, Helms MN (2020). High-mobility group box-1 increases epithelial sodium channel activity and inflammation via the receptor for advanced glycation end products. Am J Physiol Cell Physiol, 318(3), C570-C580.


  1. Damas II, Lavareze L, Scarini JF, de Lima-Souza RA, Emerick C, Gonalves MT, Figueiredo-Maciel T, Vieira GS, Kimura TC, Aquino IG, Paiva JPG, Helms MN, Mariano FV, Altemani A, Egal ESA (2022). Immunopathological insights into villitis of unknown etiology on the basis of transplant immunology. [Review]. Placenta, 131, 49-57.
  2. Tao Z, Helms MN, Leach BCB, Wu X (2022). Molecular insights into the multifaceted functions and therapeutic targeting of high mobility group box 1 in metabolic diseases. [Review]. J Cell Mol Med, 26(14), 3809-3815.
  3. Egal ESA, Scarini JF, de Lima-Souza RA, Lavareze L, Fernandes PM, Emerick C, Gonalves MT, Helms MN, Altemani A, Mariano FV (2022). Tumor microenvironment in salivary gland carcinomas: An orchestrated state of chaos. [Review]. Oral Oncol, 127, 105777.
  4. Lavareze L, Scarini JF, de Lima-Souza RA, Emerick C, Sales de S R, Aquino IG, Fernandes PM, Gonalves MT, Helms MN, Altemani A, Egal ESA, Mariano FV (2022). Salivary gland cancer in the setting of tumor microenvironment: Translational routes for therapy. [Review]. Crit Rev Oncol Hematol, 171, 103605.


  1. Helms MN, Liou TG (2021). Spotlighting "Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps": A New Catch in Cystic Fibrosis? Am J Respir Cell Mol Biol, 66(1), 5-7.