Education History
| Undergraduate |
University of Nebraska¿Lincoln |
BS |
|---|---|---|
| Graduate Training |
University of Utah |
PhD |
Selected Publications
Journal Article
- Spaltenstein P, Scherer SR, Jones TE, Giesler RJ, Kay M (2026). Total chemical synthesis of pentameric cholera toxin subunit B. Chemical communications (Cambridge, England), 62(29), 7529-7533.
- Giesler RJ, Woodham PCS, Draper SRE, Spaltenstein P, Whitby FG, Hill CP, Kay M (2025). Protein chirality as a determinant of ligand affinity: insights from l- and d-streptavidin. Chemical science, 16(48), 23342-23350.
- Spaltenstein P, Giesler RJ, Scherer SR, Erickson PW, Kay M (2025). Selective Activation of Peptide-Thioester Precursors for Templated Native Chemical Ligations. Angewandte Chemie (International ed. in English), 64(1), e202413644.
- Giesler RJ, Spaltenstein P, Jacobsen MT, Xu W, Maqueda M, Kay MS (2021). A glutamic acid-based traceless linker to address challenging chemical protein syntheses. Org Biomol Chem, 19(40), 8821-8829.
- Fulcher JM, Petersen ME, Giesler RJ, Cruz ZS, Eckert DM, Francis JN, Kawamoto EM, Jacobsen MT, Kay MS (2019). Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem, 17(48), 10237-10244.
Review
- Giesler RJ, Erickson PW, Kay MS (2020). Enhancing native chemical ligation for challenging chemical protein syntheses. [Review]. Curr Opin Chem Biol, 58, 37-44.
Book Chapter
- Jacobsen MT, Spaltenstein P, Giesler RJ, Chou DH, Kay MS (2022). Improved Handling of Peptide Segments Using Side Chain-Based "Helping Hand" Solubilizing Tools. In Li X (Ed.), Chemical Protein Synthesis. Methods in Molecular Biology (2530, pp. 81-107). New York, NY: Humana.