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Sara J. Knight

Sara J. Knight, PhD

Languages spoken: English, French

Academic Information

Departments Primary - Internal Medicine

Divisions: Epidemiology

Academic Office Information

Research Interests

  • Cancer
  • Prostate Cancer
  • Palliative Medicine
  • Genomics and Personalized Medicine
  • Quality of Life and Patient-Reported Outcomes
  • Medical Decision Making
  • Patient Values
  • Patient Preferences
  • Shared Decision Making
  • Patient and Clinician Education

Education History

Internship Rush-Presbyterian-St. Luke's Medical Center
Southern Illinois University Carbondale
Graduate Training Southern Illinois University Carbondale
University of Maryland

Selected Publications

Journal Article

  1. Stevens A, Meier J, Bhat A, Knight SJ, Vanness DJ, Balentine C (2023). Reassessing surgical guidelines for papillary thyroid cancer impact on survival: Expanding indications for lobectomy. Surgery, 174(3), 542-548.
  2. Richards JL, Knight SJ (2023). Parents' Perspectives on Secondary Genetic Ancestry Findings in Pediatric Genomic Medicine. Clin Ther.
  3. Nugent SM, Slatore CG, Winchell K, Handley R, Clayburgh D, Chandra R, Hooker ER, Knight SJ, Morasco BJ (2023). Prevalence and correlates of high-dose opioid use among survivors of head and neck cancer. Head Neck, 45(8), 2058-2067.
  4. Lemke AA, Thompson ML, Gimpel EC, McNamara KC, Rich CA, Finnila CR, Cochran ME, Lawlor JMJ, East KM, Bowling KM, Latner DR, Hiatt SM, Amaral MD, Kelley WV, Greve V, Gray DE, Felker SA, Meddaugh H, Cannon A, Luedecke A, Jackson KE, Hendon LG, Janani HM, Johnston M, Merin LA, Deans SL, Tuura C, Hughes T, Williams H, Laborde K, Neu MB, Patrick-Esteve J, Hurst ACE, Kirmse BM, Savich R, Spedale SB, Knight SJ, Barsh GS, Korf BR, Cooper GM, Brothers KB (2023). Parents' Perspectives on the Utility of Genomic Sequencing in the Neonatal Intensive Care Unit. J Pers Med, 13(7).
  5. Durstenfeld MS, Peluso MJ, Peyser ND, Lin F, Knight SJ, Djibo A, Khatib R, Kitzman H, OBrien E, Williams N, Isasi C, Kornak J, Carton TW, Olgin JE, Pletcher MJ, Marcus GM, Beatty AL (2023). Factors Associated With Long COVID Symptoms in an Online Cohort Study. Open Forum Infect Dis, 10(2), ofad047.
  6. Kraft SA, Russell H, Bensen JT, Bonini KE, Robinson JO, Sahin-Hodoglugil N, Renna K, Hindorff LA, Kaufman D, Horowitz CR, Waltz M, Zepp JM, Knight SJ (2022). Conducting clinical genomics research during the COVID-19 pandemic: Lessons learned from the CSER consortium experience. Am J Med Genet A.
  7. Hamad R, Lyman KA, Lin F, Modrow MF, Ozluk P, Azar KMJ, Goodin A, Isasi CR, Kitzman HE, Knight SJ, Marcus GM, McMahill-Walraven CN, Meissner P, Nair V, OBrien EC, Olgin JE, Peyser ND, Sylwestrzak G, Williams N, Pletcher MJ, Carton T (2022). The U.S. COVID-19 County Policy Database: a novel resource to support pandemic-related research. BMC Public Health, 22(1), 1882.
  8. Lafferty M, Winchell K, Cottrell E, Knight S, Nugent SM (2022). Women of the Gulf War: Understanding Their Military and Health Experiences Over 30 Years. Mil Med.
  9. Rentas C, Baker S, Goss L, Richman J, Knight SJ, Key C, Morris M (2022). Patients undergoing colorectal surgery at a Veterans Affairs Hospital do not experience racial disparity in length of stay either before or after implementing an enhanced recovery pathway. BMC Surg, 22(1), 201.
  10. Knight SJ, Haibach JP, Hamilton AB, Whittle J, Ono SS, Butler J, Flower M, Ray CD, Pugh MJ, Zickmund SL (2022). Veteran Engagement in Health Services Research: a Conceptual Model. J Gen Intern Med, 37(Suppl 1), 94-98.
  11. Nugent SM, Cottrell E, Knight SJ, Helfand M (2022). Health Experiences Research as a Resource and Mechanism for Veteran Engagement in VA Healthcare Research and Care Delivery. J Gen Intern Med, 37(Suppl 1), 118-122.
  12. Bowling KM, Thompson ML, Finnila CR, Hiatt SM, Latner DR, Amaral MD, Lawlor JMJ, East KM, Cochran ME, Greve V, Kelley WV, Gray DE, Felker SA, Meddaugh H, Cannon A, Luedecke A, Jackson KE, Hendon LG, Janani HM, Johnston M, Merin LA, Deans SL, Tuura C, Williams H, Laborde K, Neu MB, Patrick-Esteve J, Hurst ACE, Kandasamy J, Carlo W, Brothers KB, Kirmse BM, Savich R, Superneau D, Spedale SB, Knight SJ, Barsh GS, Korf BR, Cooper GM (2021). Genome sequencing as a first-line diagnostic test for hospitalized infants. Genet Med, 24(4), 851-861.
  13. ODaniel JM, Ackerman S, Desrosiers LR, Rego S, Knight SJ, Mollison L, Byfield G, Anderson KP, Danila MI, Horowitz CR, Joseph G, Lamoure G, Lindberg NM, McMullen CK, Mittendorf KF, Ramos MA, Robinson M, Sillari C, Madden EB, CSER Stakeholder and Engagement Work Group (2022). Integration of stakeholder engagement from development to dissemination in genomic medicine research: Approaches and outcomes from the CSER Consortium. Genet Med, 24(5), 1108-1119.
  14. Smith HS, Brothers KB, Knight SJ, Ackerman SL, Rini C, Veenstra DL, McGuire AL, Wilfond BS, Malek J (2021). Conceptualization of utility in translational clinical genomics research. Am J Hum Genet, 108(11), 2027-2036.
  15. Nugent SM, Morasco BJ, Handley R, Clayburgh D, Hooker ER, Ganzini L, Knight SJ, Chen JI, Sullivan DR, Slatore CG (2022). Risk of Suicidal Self-directed Violence Among US Veteran Survivors of Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg, 147(11), 981-989.
  16. Smith HS, Morain SR, Robinson JO, Canfield I, Malek J, Rubanovich CK, Bloss CS, Ackerman SL, Biesecker B, Brothers KB, Goytia CN, Horowitz CR, Knight SJ, Koenig B, Kraft SA, Outram S, Rini C, Shipman KJ, Waltz M, Wilfond B, McGuire AL (2021). Perceived Utility of Genomic Sequencing: Qualitative Analysis and Synthesis of a Conceptual Model to Inform Patient-Centered Instrument Development. Patient, 15(3), 317-328.
  17. Gutierrez AM, Robinson JO, Outram SM, Smith HS, Kraft SA, Donohue KE, Biesecker BB, Brothers KB, Chen F, Hailu B, Hindorff LA, Hoban H, Hsu RL, Knight SJ, Koenig BA, Lewis KL, Lich KH, ODaniel JM, Okuyama S, Tomlinson GE, Waltz M, Wilfond BS, Ackerman SL, Majumder MA (2021). Examining access to care in clinical genomic research and medicine: Experiences from the CSER Consortium. J Clin Transl Sci, 5(1), e193.
  18. Fagerlin A, Holmes-Rovner M, Hofer TP, Rovner D, Alexander SC, Knight SJ, Ling BS, A Tulsky J, Wei JT, Hafez K, Kahn VC, Connochie D, Gingrich J, Ubel PA (2021). Head to head randomized trial of two decision aids for prostate cancer. BMC Med Inform Decis Mak, 21(1), 154.
  19. Haibach JP, Hoerster KD, Dorflinger L, McAndrew LM, Cassidy DG, Goodrich DE, Bormann JE, Lowery J, Asch SM, Raffa SD, Moin T, Peterson AL, Goldstein MG, Neal-Walden T, Talcott GW, Hunter CL, Knight SJ (2020). Research translation for military and veteran health: research, practice, policy. Transl Behav Med, 11(2), 631-641.
  20. Shimada SL, Zocchi MS, Hogan TP, Kertesz SG, Rotondi AJ, Butler JM, Knight SJ, DeLaughter K, Kleinberg F, Nicklas J, Nazi KM, Houston TK (2020). Impact of Patient-Clinical Team Secure Messaging on Communication Patterns and Patient Experience: Randomized Encouragement Design Trial. J Med Internet Res, 22(11), e22307.
  21. Balentine CJ, Morris M, Knight SJ, Turan JM, Flood KL, Gutierrez-Meza D, Macdonald CL, Bhatia S, Brown CJ (2020). An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders. Ann Surg, 275(6), e752-e758.
  22. Hull O, Niranjan SJ, Wallace AS, Williams BR, Turkman YE, Ingram SA, Williams CP, Smith T, Knight SJ, Bhatia S, Rocque GB (2020). Should we be talking about guidelines with patients? A qualitative analysis in metastatic breast cancer. Breast Cancer Res Treat, 184(1), 115-121.
  23. Sheinfeld Gorin SN, Lee RE, Knight SJ (2020). Group mentoring and leadership growth in behavioral medicine. Transl Behav Med, 10(4), 873-876.
  24. Niranjan SJ, Wallace A, Williams BR, Turkman Y, Williams CP, Bhatia S, Knight S, Rocque GB (2019). Trust but Verify: Exploring the Role of Treatment-Related Information and Patient-Physician Trust in Shared Decision Making Among Patients with Metastatic Breast Cancer. J Cancer Educ, 35(5), 885-892.
  25. Ahluwalia S, Reddy NK, Johnson R, Emanuel L, Knight SJ (2020). Dyadic Model of Adaptation to Life-Limiting Illness. J Palliat Med, 23(9), 1177-1183.
  26. Niranjan SJ, Turkman Y, Williams BR, Williams CP, Halilova KI, Smith T, Knight SJ, Bhatia S, Rocque GB (2020). "I'd Want to Know, Because a Year's Not a Long Time to Prepare for a Death": Role of Prognostic Information in Shared Decision Making among Women with Metastatic Breast Cancer. J Palliat Med, 23(7), 937-943.
  27. Dos Santos Marques IC, Herbey II, Theiss LM, Hollis RH, Knight SJ, Davis TC, Fouad M, Chu DI (2020). Understanding the Surgical Experience for African-Americans and Caucasians With Enhanced Recovery. J Surg Res, 250, 12-22.
  28. May T, Cannon A, Moss IP, Nakano-Okuno M, Hardy S, Miskell EL, Kelley WV, Curry W, East KM, Acemgil A, Schach J, Sodeke SO, Fouad MN, Johnson RD, Cimino J, Richards JL, Knight SJ, Korf B (2020). Recruiting diversity where it exists: The Alabama Genomic Health Initiative. J Genet Couns, 29(3), 471-478.
  29. Goddard KAB, Angelo FAN, Ackerman SL, Berg JS, Biesecker BB, Danila MI, East KM, Hindorff LA, Horowitz CR, Hunter JE, Joseph G, Knight SJ, McGuire A, Muessig KR, Ou J, Outram S, Rahn EJ, Ramos MA, Rini C, Robinson JO, Smith HS, Waltz M, Lee SS (2020). Lessons learned about harmonizing survey measures for the CSER consortium. J Clin Transl Sci, 4(6), 537-546.
  30. Chang ME, Baker SJ, Dos Santos Marques IC, Liwo AN, Chung SK, Richman JS, Knight SJ, Fouad MN, Gakumo CA, Davis TC, Chu DI (2018). Health Literacy in Surgery. Health Lit Res Pract, 4(1), e46-e65.
  31. Graham LA, Malone EB, Richman JS, Carson AP, Affuso O, Knight SJ, Levitan EB (2019). Association of Food Access, Recreational Opportunities, and Natural Amenities with Engagement in the Veterans MOVE! Weight Management Program. Obesity (Silver Spring), 28(1), 55-64.
  32. Rocque GB, Rasool A, Williams BR, Wallace AS, Niranjan SJ, Halilova KI, Turkman YE, Ingram SA, Williams CP, Forero-Torres A, Smith T, Bhatia S, Knight SJ (2019). What Is Important When Making Treatment Decisions in Metastatic Breast Cancer? A Qualitative Analysis of Decision-Making in Patients and Oncologists. Oncologist, 24(10), 1313-1321.
  33. All of Us Research Program Investigators, Denny JC, Rutter JL, Goldstein DB, Philippakis A, Smoller JW, Jenkins G, Dishman E (2019). The "All of Us" Research Program. N Engl J Med, 381(7), 668-676.
  34. Horowitz CR, Orlando LA, Slavotinek AM, Peterson J, Angelo F, Biesecker B, Bonham VL, Cameron LD, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hindorff LA, Jarvik GP, Kaufman D, Kenny EE, Knight SJ, Koenig BA, Korf BR, Madden E, McGuire AL, Ou J, Wasserstein MP, Robinson M, Leventhal H, Sanderson SC (2019). The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research. Am J Hum Genet, 104(6), 1088-1096.
  35. Scheuner MT, Russell MM, Chanfreau-Coffinier C, Peredo J, Yano EM, Hamilton AB, Lerner B, Provenzale D, Knight SJ, Voils CI (2018). Stakeholders' views on the value of outcomes from clinical genetic and genomic interventions. Genet Med, 21(6), 1371-1380.
  36. Chanfreau-Coffinier C, Peredo J, Russell MM, Yano EM, Hamilton AB, Lerner B, Provenzale D, Knight SJ, Voils CI, Scheuner MT (2018). A logic model for precision medicine implementation informed by stakeholder views and implementation science. Genet Med, 21(5), 1139-1154.
  37. Dionne-Odom JN, Ejem D, Azuero A, Taylor RA, Rocque GB, Turkman Y, Thompson MA, Knight SJ, Martin MY, Bakitas MA (2018). Factors Associated with Family Caregivers' Confidence in Future Surrogate Decision Making for Persons with Cancer. J Palliat Med, 21(12), 1705-1712.
  38. Wahl TS, Goss LE, Morris MS, Gullick AA, Richman JS, Kennedy GD, Cannon JA, Vickers SM, Knight SJ, Simmons JW, Chu DI (2017). Enhanced Recovery After Surgery (ERAS) Eliminates Racial Disparities in Postoperative Length of Stay After Colorectal Surgery. Ann Surg, 268(6), 1026-1035.
  39. Balentine CJ, Kenzik K, Chu DI, Morris MS, Knight SJ, Brown CJ, Bhatia S (2018). Planning post-discharge destination for gastrointestinal surgery patients: Room for improvement? Am J Surg, 216(5), 912-918.
  40. Amendola LM, Berg JS, Horowitz CR, Angelo F, Bensen JT, Biesecker BB, Biesecker LG, Cooper GM, East K, Filipski K, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hassmiller-Lich K, Joseph G, Kenny EE, Koenig BA, Knight S, Kwok PY, Lewis KL, McGuire AL, Norton ME, Ou J, Parsons DW, Powell BC, Risch N, Robinson M, Rini C, Scollon S, Slavotinek AM, Veenstra DL, Wasserstein MP, Wilfond BS, Hindorff LA, CSER consortium, Plon SE, Jarvik GP (2018). The Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations. Am J Hum Genet, 103(3), 319-327.
  41. Ejem D, Dionne-Odom JN, Turkman Y, Knight SJ, Willis D, Kaufman PA, Bakitas M (2018). Incongruence between women's survey- and interview-determined decision control preferences: A mixed methods study of decision-making in metastatic breast cancer. Psychooncology, 27(8), 1950-1957.
  42. Maguen S, Metzler TJ, Bosch J, Marmar CR, Knight SJ, Neylan TC (2012). Killing in combat may be independently associated with suicidal ideation. Depress Anxiety, 29(11), 918-23.
  43. Odierna DH, Afable-Munsuz A, Ikediobi O, Beattie M, Knight S, Ko M, Wilson A, Ponce NA (2011). Early developments in gene-expression profiling of breast tumors: potential for increasing black-white patient disparities in breast cancer outcomes? Per Med, 8(6), 669-679.
  44. Arar N, Knight SJ, Modell SM, Issa AM (2018). The Genome-based Knowledge Management in Cycles model: a complex adaptive systems framework for implementation of genomic applications. Per Med, 8(2), 191-205.
  45. Smith AK, Cenzer IS, Knight SJ, Puntillo KA, Widera E, Williams BA, Boscardin WJ, Covinsky KE (2010). The epidemiology of pain during the last 2 years of life. Ann Intern Med, 153(9), 563-9.
  46. Lin GA, Aaronson DS, Knight SJ, Carroll PR, Dudley RA (2009). Patient decision aids for prostate cancer treatment: a systematic review of the literature. CA Cancer J Clin, 59(6), 379-90.
  47. Kramer MD, Lightfoot AC, Knight S, Cazier CF, Olson LM (2003). Classroom injuries in Utah public schools. Acad Emerg Med, 10(9), 978-84.
  48. Knight SJ, Chmiel JS, Kuzel T, Sharp L, Albers M, Fine R, Moran EM, Nadler RB, Sharifi R, Bennett CL (1998). Quality of life in metastatic prostate cancer among men of lower socioeconomic status: feasibility and criterion related validity of 3 measures. J Urol, 160(5), 1765-9.
  49. Cartwright RD, Knight S (1987). Silent partners: the wives of sleep apneic patients. Sleep, 10(3), 244-8.


  1. Smith HS, Morain SR, Robinson JO, Canfield I, Malek J, Rubanovich CK, Bloss CS, Ackerman SL, Biesecker B, Brothers KB, Goytia CN, Horowitz CR, Knight SJ, Koenig B, Kraft SA, Outram S, Rini C, Shipman KJ, Waltz M, Wilfond B, McGuire AL (2021). Perceived Utility of Genomic Sequencing: Qualitative Analysis and Synthesis of a Conceptual Model to Inform Patient-Centered Instrument Development. [Review]. Patient, 15(3), 317-328.