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Shuanghu Liu, MD, PhD

Languages spoken: English

Academic Information

Departments Primary - Medicinal Chemistry

Academic Office Information

shuanghu.liu@hsc.utah.edu

Education History

Professional Medical Zhongshan Medical University
 MD
Residency Hunan Medical University
 Resident
Graduate Training Hunan Medical University
 MS
Residency Hunan Medical University
 Resident
Doctoral Training Hunan Medical University
 PhD
Postdoctoral Fellowship University of Miami
 Postdoctoral Fellow
Postdoctoral Fellowship University of Nebraska
 Postdoctoral Fellow
Postdoctoral Training University of Kentucky
 Postdoctoral Training

Selected Publications

Journal Article

  1. Chandra PK, Bao L, Song K, Aboulnasr FM, Baker DP, Shores N, Wimley WC, Liu S, Hagedorn CH, Fuchs SY, Wu T, Balart LA, Dash S (2014). HCV infection selectively impairs type I but not type III IFN signaling. Am J Pathol, 184(1), 214-29.
  2. Liu S, Nelson CA, Xiao L, Lu L, Seth PP, Davis DR, Hagedorn CH (2011). Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase. Antiviral Res, 89(1), 54-63.
  3. Yahoob J, Hu G, Fan X, Yang H, Liu S, Tan D, Li T, Zhang Z (2000). Diversity of Helicobacter pylori among Chinese persons with H. pylori infection. APMIS, 108, 482-6.
  4. Liu S, Chen R, Hagedorn C (2014). Direct visualization of hepatitis C virus-infected Huh7.5 cells with a high titre of infectious chimeric JFH1-EGFP reporter virus in three-dimensional Matrigel cell cultures. The Journal of general virology, 95(Pt 2), 423-33.
  5. Lu L, Murohy D, Chunhua L, Liu (2008). Complete genomes of three subtype 6t isolates and analysis of many novel hepatitis C virus variants within genotype 6. The Journal of general virology, 89, 444-452.
  6. Liu S, Ansari IH, Das SC, Pattnaik A (2006). Insertion and deletion analyses identify regions of non-structural protein 5A of Hepatitis C virus that are dispensable for viral genome replication. The Journal of general virology, 87, 323-327.
  7. Smalling RL, Delker DA, Zhang Y, Nieto N, McGuiness MS, Liu S, Friedman SL, Hagedorn CH, Wang L (2013). Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease. American journal of physiology. Gastrointestinal and liver physiology, 305(5), G364-74.
  8. Li C, Tan D, Liu (2001). Effect of artificial liver support system on the patients with severe hepatitis. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 26(4), 377-378.
  9. Liu S, Xiao L, Nelson C, Hagedorn C (2012). A Cell Culture Adapted HCV JFH1 Variant That Increases Viral Titers and Permits the Production of High Titer Infectious Chimeric Reporter Viruses. PloS one, 7(9), e44965.
  10. Liu S, Chen R, Hagedorn CH (2016). Tannic Acid Inhibits Hepatitis C Virus Entry into Huh7.5 Cells. PloS one, 10(7), e0131358.
  11. Papic N, Maxwell C, Delker D, Liu S, Heale BE, Hagedorn C (2012). RNA-Sequencing Analysis of 5' Capped RNAs Identifies Many New Differentially Expressed Genes in Acute Hepatitis C Virus Infection. Viruses, 4(4), 581-612.
  12. Meyer K, Kwon YC, Liu S, Hagedorn CH, Ray RB, Ray (2015). Interferon-¿ inducible protein 6 impairs EGFR activation by CD81 and inhibits hepatitis C virus infection. Scientific reports, (5), 9012.
  13. Liu S, Zhang Z, Hu G, Tan (1998). Expression of E1, E2/N1 and NS5 genes of hepatitis C virus in E.coli and preliminary use of the expressed proteins. 16(1), 5-8.
  14. Tan D, Liu S, Li (2000). Specific cellular and humoral immune responses in BALB/C mice induced by DNA immunization of HCV Core gene. 10(1), 78-79.
  15. Tan D, Liu S, Li (2001). Specific Immune Responses against Hepatitis B Virus Following Immunization with the DNA Vaccine containing HBV pan-S Gene in Mice. 16(3), 280-282.

Abstract

  1. Liu S, Nelson C, Lu L, Davis D, Hagedorn CH (2012). Development of a High Titer Infectious Renilla Luciferase Reporter HCV and use in Testing Antiviral Activity of Novel Small Molecules That Bind the HCV IRES. Gastroenterology, 138(5), S-788-S-788.
  2. Maxwell CI, Delker D, Liu S, Nelson CA, Nix DA, Folkers ME, Hagedorn C (2012). RNA-Sequencing Analysis of 5' Capped RNA in HCV Infected Cirrhotic Liver, Acutely HCV Infected Huh 7.5 Cells, and Control Specimens Identifies Common Upregulated Known and Novel Gene. Gastroenterology, 138(5), S-788-S-788.