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XiaoYong Yang, PhD

Languages spoken: English

Academic Information

Departments Primary - Biochemistry

Education History

Postdoctoral Fellowship University of Utah
 Postdoctoral Fellow
Postdoctoral Fellowship University of California, San Francisco
 Postdoctoral Fellow
Doctoral Training Albert Einstein College of Medicine
 PhD
Graduate Training HeiLongJiang University of Chinese Medicine
 MS
Undergraduate HeiLongJiang University of Chinese Medicine
 BS

Selected Publications

Journal Article

  1. Yang X, Wang Q, Cao E (2020). Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. Nat Commun, 11(1), 1016. (Read full article)
  2. Yang XY, Stanley RE, Ross AP, Robitaille AM, Gray JA, Cheyette BNR (2017). Sestd1 Encodes a Developmentally Dynamic Synapse Protein That Complexes With BCR Rac1-GAP to Regulate Forebrain Dendrite, Spine and Synapse Formation. Cereb Cortex, 29(2), 505-516. (Read full article)
  3. Zheng W, Yang X, Hu R, Cai R, Hofmann L, Wang Z, Hu Q, Liu X, Bulkley D, Yu Y, Tang J, Flockerzi V, Cao Y, Cao E, Chen XZ (2018). Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. Nat Commun, 9(1), 2302. (Read full article)
  4. Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D, Clapham DE, Cao E (2016). The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs. Cell, 167(3), 763-773.e11. (Read full article)
  5. Yang X, Fisher DA, Cheyette BN (2013). SEC14 and Spectrin Domains 1 (Sestd1), Dishevelled 2 (Dvl2) and Dapper Antagonist of Catenin-1 (Dact1) co-regulate the Wnt/Planar Cell Polarity (PCP) pathway during mammalian development. Commun Integr Biol, 6(6), e26834. (Read full article)
  6. Martin PM, Yang X, Robin N, Lam E, Rabinowitz JS, Erdman CA, Quinn J, Weiss LA, Hamilton SP, Kwok PY, Moon RT, Cheyette BN (2013). A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation. Transl Psychiatry, 3(9), e301. (Read full article)
  7. Yang X, Cheyette BN (2013). SEC14 and spectrin domains 1 (Sestd1) and Dapper antagonist of catenin 1 (Dact1) scaffold proteins cooperatively regulate the Van Gogh-like 2 (Vangl2) four-pass transmembrane protein and planar cell polarity (PCP) pathway during embryonic development in mice. J Biol Chem, 288(28), 20111-20. (Read full article)
  8. Arguello A, Yang X, Vogt D, Stanco A, Rubenstein JL, Cheyette BN (2013). Dapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneurons. PLoS One, 8(6), e67679. (Read full article)
  9. Suk HY, Zhou C, Yang TT, Zhu H, Yu RY, Olabisi O, Yang X, Brancho D, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Lefer DJ, Molkentin JD, Ghigo A, Hirsch E, Jin J, Chow CW (2012). Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. J Biol Chem, 288(5), 3477-88. (Read full article)
  10. Kivime S, Yang XY, Cheyette BN (2011). All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. BMC Biochem, 12, 33. (Read full article)
  11. Zhu H, Suk HY, Yu RY, Brancho D, Olabisi O, Yang TT, Yang X, Zhang J, Moussaif M, Durand JL, Jelicks LA, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Duranski MR, Lefer DJ, Huston E, Baillie GS, Houslay MD, Molkentin JD, Jin J, Chow CW (2010). Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D. Mol Cell Biol, 30(18), 4379-90. (Read full article)
  12. Louie SH, Yang XY, Conrad WH, Muster J, Angers S, Moon RT, Cheyette BN (2009). Modulation of the beta-catenin signaling pathway by the dishevelled-associated protein Hipk1. PLoS One, 4(2), e4310. (Read full article)
  13. Olabisi OA, Soto-Nieves N, Nieves E, Yang TT, Yang X, Yu RY, Suk HY, Macian F, Chow CW (2008). Regulation of transcription factor NFAT by ADP-ribosylation. Mol Cell Biol, 28(9), 2860-71. (Read full article)
  14. Yang XY, Yang TT, Schubert W, Factor SM, Chow CW (2006). Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol, 303(2), 825-37. (Read full article)
  15. Yang TT, Suk HY, Yang X, Olabisi O, Yu RY, Durand J, Jelicks LA, Kim JY, Scherer PE, Wang Y, Feng Y, Rossetti L, Graef IA, Crabtree GR, Chow CW (2006). Role of transcription factor NFAT in glucose and insulin homeostasis. Mol Cell Biol, 26(20), 7372-87. (Read full article)
  16. Schubert W, Yang XY, Yang TT, Factor SM, Lisanti MP, Molkentin JD, Rincon M, Chow CW (2003). Requirement of transcription factor NFAT in developing atrial myocardium. J Cell Biol, 161(5), 861-74. (Read full article)