Yves Lussier

Yves Lussier, MD, FACMI, FAMIA

Languages spoken: English, French

Academic Information

Departments Primary - Biomedical Informatics

Lab

Board Certification

  • Licentiate of the Medical Council of Canada

Yves A. Lussier, MD, FAMIA, FACMI is the Chair of Biomedical Informatics at University of Utah School of Medicine. As a professional engineer and physician-scientist, he is an international expert in translational bioinformatics and a pioneer in research informatics techniques including systems biology, data representation through ontologies, and high-throughput methods in personalized medicine.

Dr. Lussier comes to the University Utah from the University of Arizona, where he was the Associate Vice President for Information Science and Chief Knowledge Officer of the UArizona Health Sciences (UAHS), Founding Director of the Center for Biomedical Informatics and Biostatistics, and Professor of Medicine. During his time at UArizona, he developed novel programs in biomedical informatics, computational genomics, and precision health, as well as provided critical leadership to advance precision health approaches to health outcomes and healthcare delivery and in the development of big data analytical tools and resource services. Prior to his tenure at UArizona, Dr. Lussier was professor of medicine, bioengineering and biopharmaceutical sciences at University of Illinois at Chicago (UIC), and assistant vice president for health affairs and chief research information officer for the University of Illinois Hospital and Health Sciences System (2011-13). From 2006-2011, he was the associate director of informatics for the University of Chicago Comprehensive Cancer Center as well as co-director of biomedical informatics for the Clinical and Translational Science Award (CTSA)-funded Institute for Translational Medicine. From 2001-2006, Dr. Lussier was an assistant professor in the Departments of Biomedical Informatics and Medicine at Columbia University in New York.

Lussier’s research group conducts pioneering hypothesis-driven computational modeling predictions in precision medicine that are then validated in vitro, in vivo and in clinical trials. As a leader of the fields of translational bioinformatics and of Data Science-augmented precision medicine, he has launched successful companies and international conferences, authored 185 publications, and delivered more than 100 invited presentations in precision medicine, systems medicine, and translational bioinformatics, including 28 opening keynotes at international conferences. He has been awarded $190,000,000 in grants as principal, core leader, or co-investigator, and mentored or co-mentored over 90 graduates, post graduate fellows, and junior faculty members, of which twelve are faculty members, seven obtained K-awards, and five obtained R awards. Dr. Lussier’s honors include three IBM Faculty Awards, inducted Fellow of the American College of Medical Informatics (ACMI), 1st recipient of the Columbia University Faculty Mentoring Award, “Ambassador for Health Sciences” at the University of Sherbrooke (Canada), and 16 outstanding publication awards from the American Medical Informatics Association (AMIA), the International Society for Computational Biology (ISCB), and the Translational Bioinformatics Conference (TBC). In 2016, Dr. Lussier was invited among ten USA academic leaders invited by the White House for its Precision Medicine Summit.

Education History

Undergraduate University of Sherbrooke
 BEng
Professional Medical University of Sherbrooke
 MD
Internship Université Laval
 Clinical Internship
Residency University of Sherbrooke
 Resident
Postdoctoral Fellowship Columbia University
 Postdoctoral Research Fellow

Selected Publications

Journal Article

  1. Desai AA, Lei Z, Bahroos N, Maienschein-Cline M, Saraf SL, Zhang X, Shah BN, Nouraie SM, Abbasi T, Patel AR, Lang RM, Lussier Y, Garcia JGN, Gordeuk VR, Machado R (2017). Association of circulating transcriptomic profiles with mortality in sickle cell disease. Blood, 129(22), 3009-3016. (Read full article)
  2. Li Z, Huang H, Li Y, Jiang X, Chen P, Arnovitz S, Radmacher MD, Maharry K, Elkahloun A, Yang X, He C, He M, Zhang Z, Dohner K, Neilly MB, Price C, Lussier YA, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Bullinger L, Valk PJ, Delwel R, Lowenberg B, Liu PP, Marcucci G, Bloomfield CD, Rowley JD, Chen (2012). Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. Blood, 119(10), 2314-24. (Read full article)
  3. Krive J, Patel M, Gehm L, Mackey M, Kulstad E, Li JJ, Lussier YA, Boyd A (2015). The complexity and challenges of the International Classification of Diseases, Ninth Revision, Clinical Modification to International Classification of Diseases, 10th Revision, Clinical Modification transition in EDs. The American journal of emergency medicine, 33(5), 713-8. (Read full article)
  4. Wang T, Lang GD, Moreno-Vinasco L, Huang Y, Goonewardena SN, Peng YJ, Svensson EC, Natarajan V, Lang RM, Linares JD, Breysse PN, Geyh AS, Samet JM, Lussier YA, Dudley S, Prabhakar NR, Garcia J (2012). Particulate matter induces cardiac arrhythmias via dysregulation of carotid body sensitivity and cardiac sodium channels. American journal of respiratory cell and molecular biology, 46(4), 524-31. (Read full article)
  5. Sammani S, Park KS, Zaidi SR, Mathew B, Wang T, Huang Y, Zhou T, Lussier YA, Husain AN, Moreno-Vinasco L, Vigneswaran WT, Garcia J (2011). A sphingosine 1-phosphate 1 receptor agonist modulates brain death-induced neurogenic pulmonary injury. American journal of respiratory cell and molecular biology, 45(5), 1022-7. (Read full article)
  6. Mathew B, Huang Y, Jacobson JR, Berdyshev E, Gerhold LM, Wang T, Moreno-Vinasco L, Lang G, Zhao Y, Chen CT, LaRiviere PJ, Mauceri H, Sammani S, Husain AN, Dudek SM, Natarajan V, Lussier YA, Weichselbaum RR, Garcia J (2011). Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression. American journal of respiratory cell and molecular biology, 44(3), 415-22. (Read full article)
  7. Mirzapoiazova T, Moitra J, Moreno-Vinasco L, Sammani S, Turner JR, Chiang ET, Evenoski C, Wang T, Singleton PA, Huang Y, Lussier YA, Watterson DM, Dudek SM, Garcia J (2011). Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury. American journal of respiratory cell and molecular biology, 44(1), 40-52. (Read full article)
  8. Lussier YA, Maksud M, Desruisseaux B, Yale PP, St-Arneault (1992). PureMD: a Computerized Patient Record software for direct data entry by physicians using a keyboard-free pen-based portable computer. Proceedings. Symposium on Computer Applications in Medical Care, 261-4. (Read full article)
  9. Grant A, Lussier Y, Delisle E, Dubois S, Bernier (1992). The TEAM evaluation approach to Project FAMUS, a pan-Canadian risk register for primary care. Proceedings. Symposium on Computer Applications in Medical Care, 734-8. (Read full article)
  10. Schissler AG, Piegorsch WW, Lussier Y (2018). Testing for differentially expressed genetic pathways with single-subject N-of-1 data in the presence of inter-gene correlation. Statistical methods in medical research, 27(12), 3797-3813. (Read full article)
  11. Amin AD, Rajan SS, Liang WS, Pongtornpipat P, Groysman MJ, Tapia EO, Peters TL, Cuyugan L, Adkins J, Rimsza LM, Lussier YA, Puvvada SD, Schatz J (2015). Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors. Cancer research, 75(14), 2916-27. (Read full article)
  12. Wang T, Moreno-Vinasco L, Huang Y, Lang GD, Linares JD, Goonewardena SN, Grabavoy A, Samet JM, Geyh AS, Breysse PN, Lussier YA, Natarajan V, Garcia J (2008). Murine lung responses to ambient particulate matter: genomic analysis and influence on airway hyperresponsiveness. Environmental health perspectives, 116(11), 1500-8. (Read full article)
  13. Mathew B, Jacobson JR, Berdyshev E, Huang Y, Sun X, Zhao Y, Gerhold LM, Siegler J, Evenoski C, Wang T, Zhou T, Zaidi R, Moreno-Vinasco L, Bittman R, Chen CT, LaRiviere PJ, Sammani S, Lussier YA, Dudek SM, Natarajan V, Weichselbaum RR, Garcia J (2011). Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs. FASEB journal, 25(10), 3388-400. (Read full article)
  14. Meyer NJ, Huang Y, Singleton PA, Sammani S, Moitra J, Evenoski CL, Husain AN, Mitra S, Moreno-Vinasco L, Jacobson JR, Lussier YA, Garcia J (2009). GADD45a is a novel candidate gene in inflammatory lung injury via influences on Akt signaling. FASEB journal, 23(5), 1325-37. (Read full article)
  15. Patwa LG, Fan TJ, Tchaptchet S, Liu Y, Lussier YA, Sartor RB, Hansen J (2011). Chronic intestinal inflammation induces stress-response genes in commensal Escherichia coli. Gastroenterology, 141(5), 1842-51.e1-10. (Read full article)
  16. Grassi MA, Tikhomirov A, Ramalingam S, Lee KE, Hosseini SM, Klein BE, Klein R, Lussier YA, Cox NJ, Nicolae D (2012). Replication analysis for severe diabetic retinopathy. Investigative ophthalmology & visual science, 53(4), 2377-81. (Read full article)
  17. Lussier A, Davis A, Lussier Y, Lebel (1989). Comparative gastrointestinal blood loss associated with placebo, aspirin, and nabumetone as assessed by radiochromium (51Cr). Journal of clinical pharmacology, 29(3), 225-9. (Read full article)
  18. Lussier YA, Rothwell DJ, Côté R (1998). The SNOMED model: a knowledge source for the controlled terminology of the computerized patient record. Methods of information in medicine, 37(2), 161-4. (Read full article)
  19. Jabado OJ, Liu Y, Conlan S, Quan PL, Hegyi H, Lussier Y, Briese T, Palacios G, Lipkin W (2008). Comprehensive viral oligonucleotide probe design using conserved protein regions. Nucleic acids research, 36(1), e3. (Read full article)
  20. Rajan SS, Amin AD, Li L, Rolland DC, Li H, Kwon D, Kweh MF, Arumov A, Roberts ER, Yan A, Basrur V, Elenitoba-Johnson KSJ, Chen XS, Puvvada SD, Lussier YA, Bilbao D, Lim MS, Schatz J (2020). The mechanism of cancer drug addiction in ALK-positive T-Cell lymphoma. Oncogene, 39(10), 2103-2117. (Read full article)
  21. Bikkavilli RK, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, Edwards MG, Rathinam MK, Zhou T, Tauler J, Borowicz S, Lussier YA, Parr BA, Cool CD, Winn R (2015). Wnt7a is a novel inducer of ß-catenin-independent tumor-suppressive cellular senescence in lung cancer. Oncogene, 34(42), 5317-28. (Read full article)
  22. Caskey R, Zaman J, Nam H, Chae SR, Williams L, Mathew G, Burton M, Li JJ, Lussier YA, Boyd A (2014). The transition to ICD-10-CM: challenges for pediatric practice. Pediatrics, 134(1), 31-6. (Read full article)
  23. Kim H, Lussier YA, Noh OK, Li H, Oh YT, Heo (2014). Prognostic implication of pulmonary function at the beginning of postoperative radiotherapy in non-small cell lung cancer. Radiotherapy and oncology, 113(3), 374-8. (Read full article)
  24. Lussier A, Arsenault A, Varady J, de Médicis R, Lussier Y, LeBel (1988). The use of a 51Cr technique to detect gastrointestinal microbleeding associated with nonsteroidal antiinflammatory drugs. Seminars in arthritis and rheumatism, 17(3 Suppl 2), 40-5. (Read full article)
  25. Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau M (2011). An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Seminars in oncology, 38(2), 215-24. (Read full article)
  26. Bime C, Pouladi N, Sammani S, Batai K, Casanova N, Zhou T, Kempf CL, Sun X, Camp SM, Wang T, Kittles RA, Lussier YA, Jones TK, Reilly JP, Meyer NJ, Christie JD, Karnes JH, Gonzalez-Garay M, Christiani DC, Yates CR, Wurfel MM, Meduri GU, Garcia JG (2018). Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor. American journal of respiratory and critical care medicine, 197(11), 1421-1432. (Read full article)
  27. Huang Y, Ma SF, Espindola MS, Vij R, Oldham JM, Huffnagle GB, Erb-Downward JR, Flaherty KR, Moore BB, White ES, Zhou T, Li J, Lussier YA, Han MK, Kaminski N, Garcia JGN, Hogaboam CM, Martinez FJ, Noth I, COMET-IPF Investigators (2017). Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine, 196(2), 208-219. (Read full article)
  28. Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, Kotha SR, Gurney TO, Parinandi NL, Lussier YA, Garcia JG, Natarajan (2014). The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis. American journal of respiratory and critical care medicine, 189(11), 1402-15. (Read full article)
  29. Hong SB, Huang Y, Moreno-Vinasco L, Sammani S, Moitra J, Barnard JW, Ma SF, Mirzapoiazova T, Evenoski C, Reeves RR, Chiang ET, Lang GD, Husain AN, Dudek SM, Jacobson JR, Ye SQ, Lussier YA, Garcia J (2008). Essential role of pre-B-cell colony enhancing factor in ventilator-induced lung injury. American journal of respiratory and critical care medicine, 178(6), 605-17. (Read full article)
  30. Chen JL, Li J, Kiriluk KJ, Rosen AM, Paner GP, Antic T, Lussier YA, Vander Griend D (2012). Deregulation of a Hox protein regulatory network spanning prostate cancer initiation and progression. Clinical cancer research, 18(16), 4291-302. (Read full article)
  31. Gardeux V, Berghout J, Achour I, Schissler AG, Li Q, Kenost C, Li J, Shang Y, Bosco A, Saner D, Halonen MJ, Jackson DJ, Li H, Martinez FD, Lussier Y (2017). A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations. Journal of the American Medical Informatics Association, 24(6), 1116-1126. (Read full article)
  32. Boyd AD, Li JJ, Kenost C, Joese B, Yang YM, Kalagidis OA, Zenku I, Saner D, Bahroos N, Lussier Y (2015). Metrics and tools for consistent cohort discovery and financial analyses post-transition to ICD-10-CM. Journal of the American Medical Informatics Association, 22(3), 730-7. (Read full article)
  33. Boyd AD, Yang YM, Li J, Kenost C, Burton MD, Becker B, Lussier Y (2015). Challenges and remediation for Patient Safety Indicators in the transition to ICD-10-CM. Journal of the American Medical Informatics Association, 22(1), 19-28. (Read full article)
  34. Gardeux V, Achour I, Li J, Maienschein-Cline M, Li H, Pesce L, Parinandi G, Bahroos N, Winn R, Foster I, Garcia JG, Lussier Y (2014). 'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine. Journal of the American Medical Informatics Association, 21(6), 1015-25. (Read full article)
  35. Boyd AD, Li JJ, Burton MD, Jonen M, Gardeux V, Achour I, Luo RQ, Zenku I, Bahroos N, Brown SB, Vanden Hoek T, Lussier Y (2013). The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools. Journal of the American Medical Informatics Association, 20(4), 708-17. (Read full article)
  36. Lee Y, Li H, Li J, Rebman E, Achour I, Regan KE, Gamazon ER, Chen JL, Yang XH, Cox NJ, Lussier Y (2013). Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases. Journal of the American Medical Informatics Association, 20(4), 619-29. (Read full article)
  37. Regan K, Wang K, Doughty E, Li H, Li J, Lee Y, Kann MG, Lussier Y (2012). Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants. Journal of the American Medical Informatics Association, 19(2), 306-16. (Read full article)
  38. Li H, Lee Y, Chen JL, Rebman E, Li J, Lussier Y (2012). Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory. Journal of the American Medical Informatics Association, 19(2), 295-305. (Read full article)
  39. Lussier YA, Stadler WM, Chen J (2012). Advantages of genomic complexity: bioinformatics opportunities in microRNA cancer signatures. Journal of the American Medical Informatics Association, 19(2), 156-60. (Read full article)
  40. Chen JL, Li J, Stadler WM, Lussier Y (2011). Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence. Journal of the American Medical Informatics Association, 18(4), 392-402. (Read full article)
  41. Sarkar IN, Butte AJ, Lussier YA, Tarczy-Hornoch P, Ohno-Machado (2011). Translational bioinformatics: linking knowledge across biological and clinical realms. Journal of the American Medical Informatics Association, 18(4), 354-7. (Read full article)
  42. Bales ME, Lussier YA, Johnson S (2007). Topological analysis of large-scale biomedical terminology structures. Journal of the American Medical Informatics Association, 14(6), 788-97. (Read full article)
  43. Friedman C, Shagina L, Lussier Y, Hripcsak (2004). Automated encoding of clinical documents based on natural language processing. Journal of the American Medical Informatics Association, 11(5), 392-402. (Read full article)
  44. Palacios G, Quan PL, Jabado OJ, Conlan S, Hirschberg DL, Liu Y, Zhai J, Renwick N, Hui J, Hegyi H, Grolla A, Strong JE, Towner JS, Geisbert TW, Jahrling PB, Büchen-Osmond C, Ellerbrok H, Sanchez-Seco MP, Lussier Y, Formenty P, Nichol MS, Feldmann H, Briese T, Lipkin W (2007). Panmicrobial oligonucleotide array for diagnosis of infectious diseases. Emerging infectious diseases, 13(1), 73-81. (Read full article)
  45. Yang X, Lee Y, Fan H, Sun X, Lussier Y (2010). Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers. Chinese science bulletin = Kexue tongbao, 55(31), 3576-3589. (Read full article)
  46. Lussier YA, Bourque (1997). Comparing SNOMED and ICPC retrieval accuracies using relational database models. Proceedings, 514-8. (Read full article)
  47. Wang AL, Rao VR, Chen JJ, Lussier YA, Rehman J, Huang Y, Jager RD, Grassi M (2014). Role of FAM18B in diabetic retinopathy. Molecular vision, 20, 1146-59. (Read full article)
  48. Vitali F, Berghout J, Fan J, Li J, Li Q, Li H, Lussier Y (2019). Precision drug repurposing via convergent eQTL-based molecules and pathway targeting independent disease-associated polymorphisms. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 24, 308-319. (Read full article)
  49. Han J, Li J, Achour I, Pesce L, Foster I, Li H, Lussier Y (2018). Convergent downstream candidate mechanisms of independent intergenic polymorphisms between co-classified diseases implicate epistasis among noncoding elements. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 23, 524-535. (Read full article)
  50. Lussier YA, Berghout J, Vitali F, Ramos KS, Kann M, Moore J (2018). Reading Between the Genes: Computational Models to Discover Function from Noncoding DNA. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 23, 507-511. (Read full article)
  51. Zaim SR, Li Q, Schissler AG, Lussier Y (2018). Emergence of pathway-level composite biomarkers from converging gene set signals of heterogeneous transcriptomic responses. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 23, 484-495. (Read full article)
  52. Berghout J, Li Q, Pouladi N, Li J, Lussier Y (2018). Single subject transcriptome analysis to identify functionally signed gene set or pathway activity. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 23, 400-411. (Read full article)
  53. Perez-Rathke A, Li H, Lussier Y (2013). Interpreting personal transcriptomes: personalized mechanism-scale profiling of RNA-seq data. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 159-70. (Read full article)
  54. Sam L, Liu Y, Li J, Friedman C, Lussier Y (2007). Discovery of protein interaction networks shared by diseases. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 76-87. (Read full article)
  55. Stevens R, Bodenreider O, Lussier Y (2006). Semantic webs for life sciences. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 112-5. (Read full article)
  56. Lussier Y, Borlawsky T, Rappaport D, Liu Y, Friedman (2006). PhenoGO: assigning phenotypic context to gene ontology annotations with natural language processing. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 64-75. (Read full article)
  57. Cantor MN, Sarkar IN, Bodenreider O, Lussier Y (2005). Genestrace: phenomic knowledge discovery via structured terminology. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 103-14. (Read full article)
  58. Sarkar IN, Cantor MN, Gelman R, Hartel F, Lussier Y (2003). Linking biomedical language information and knowledge resources: GO and UMLS. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 439-50. (Read full article)
  59. Lussier YA, Li (2004). Terminological mapping for high throughput comparative biology of phenotypes. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 202-13. (Read full article)
  60. Boyd AD, Dunn Lopez K, Lugaresi C, Macieira T, Sousa V, Acharya S, Balasubramanian A, Roussi K, Keenan GM, Lussier YA, Li J', Burton M, Di Eugenio (2018). Physician nurse care: A new use of UMLS to measure professional contribution: Are we talking about the same patient a new graph matching algorithm?. International journal of medical informatics, 113, 63-71. (Read full article)
  61. Schissler AG, Li Q, Chen JL, Kenost C, Achour I, Billheimer DD, Li H, Piegorsch WW, Lussier Y (2016). Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells. Bioinformatics (Oxford, England), 32(12), i80-i89. (Read full article)
  62. Schissler AG, Gardeux V, Li Q, Achour I, Li H, Piegorsch WW, Lussier Y (2015). Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival. Bioinformatics (Oxford, England), 31(12), i293-302. (Read full article)
  63. Maienschein-Cline M, Lei Z, Gardeux V, Abbasi T, Machado RF, Gordeuk V, Desai AA, Saraf S, Bahroos N, Lussier (2014). ARTS: automated randomization of multiple traits for study design. Bioinformatics (Oxford, England), 30(11), 1637-9. (Read full article)
  64. Yang X, Li J, Lee Y, Lussier Y (2011). GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns. Bioinformatics (Oxford, England), 27(10), 1444-6. (Read full article)
  65. Tao Y, Sam L, Li J, Friedman C, Lussier Y (2007). Information theory applied to the sparse gene ontology annotation network to predict novel gene function. Bioinformatics (Oxford, England), 23(13), i529-38. (Read full article)
  66. Friedman C, Borlawsky T, Shagina L, Xing HR, Lussier Y (2006). Bio-Ontology and text: bridging the modeling gap. Bioinformatics (Oxford, England), 22(19), 2421-9. (Read full article)
  67. Tao Y, Friedman C, Lussier Y (2005). Visualizing information across multidimensional post-genomic structured and textual databases. Bioinformatics (Oxford, England), 21(8), 1659-67. (Read full article)
  68. Tao Y, Wang D, Shortliffe EH, Lussier Y (2002). Extended attributes of event monitor systems for criteria-based notification modalities. Proceedings. AMIA Symposium, 762-6. (Read full article)
  69. Lussier YA, Sarkar IN, Cantor (2002). An integrative model for in-silico clinical-genomics discovery science. Proceedings. AMIA Symposium, 469-73. (Read full article)
  70. Kukafka R, Lussier YA, Eng P, Patel VL, Cimino J (2002). Web-based tailoring and its effect on self-efficacy: results from the MI-HEART randomized controlled trial. Proceedings. AMIA Symposium, 410-4. (Read full article)
  71. Cantor MN, Lussier Y (2002). A knowledge framework for computational molecular-disease relationships in cancer. Proceedings. AMIA Symposium, 101-5. (Read full article)
  72. Kukafka R, Lussier YA, Patel VL, Cimino J (1999). Modeling patient response to acute myocardial infarction: implications for a tailored technology-based program to reduce patient delay. Proceedings. AMIA Symposium, 570-4. (Read full article)
  73. Lussier YA, Kukafka R, Patel VL, Cimino J (2000). Formal combinations of guidelines: a requirement for self-administered personalized health education. Proceedings. AMIA Symposium, 522-6. (Read full article)
  74. Lussier YA, Shagina L, Friedman (2001). Automating SNOMED coding using medical language understanding: a feasibility study. Proceedings. AMIA Symposium, 418-22. (Read full article)
  75. Liu H, Lussier YA, Friedman (2001). A study of abbreviations in the UMLS. Proceedings. AMIA Symposium, 393-7. (Read full article)
  76. Cantor MN, Lussier Y (2004). Mining OMIM for insight into complex diseases. Studies in health technology and informatics, 107(Pt 2), 753-7. (Read full article)
  77. Wang X, Quek HN, Cantor M, Kra P, Schultz A, Lussier Y (2004). Automating terminological networks to link heterogeneous biomedical databases. Studies in health technology and informatics, 107(Pt 1), 555-9. (Read full article)
  78. Tao Y, Mendonça EA, Lussier Y (2004). A tool for abstracting relevant classes of concepts: the Common Ancestry Summarizer. Studies in health technology and informatics, 107(Pt 1), 449-53. (Read full article)
  79. Cantor MN, Sarkar IN, Gelman R, Hartel F, Bodenreider O, Lussier Y (2003). An evaluation of hybrid methods for matching biomedical terminologies: mapping the gene ontology to the UMLS. Studies in health technology and informatics, 95, 62-7. (Read full article)
  80. Kukafka R, Lussier YA, Patel VL, Cimino J (2001). Developing tailored theory-based educational content for WEB applications: illustrations from the MI-HEART project. Studies in health technology and informatics, 84(Pt 2), 1474-8. (Read full article)
  81. Nonas SA, Moreno-Vinasco L, Ma SF, Jacobson JR, Desai AA, Dudek SM, Flores C, Hassoun PM, Sam L, Ye SQ, Moitra J, Barnard J, Grigoryev DN, Lussier YA, Garcia J (2007). Use of consomic rats for genomic insights into ventilator-associated lung injury. American journal of physiology. Lung cellular and molecular physiology, 293(2), L292-302. (Read full article)
  82. Zaim SR, Kenost C, Berghout J, Chiu W, Wilson L, Zhang HH, Lussier Y (2020). Correction to: binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions. BMC bioinformatics, 21(1), 495. (Read full article)
  83. Rachid Zaim S, Kenost C, Berghout J, Chiu W, Wilson L, Zhang HH, Lussier Y (2020). binomialRF: interpretable combinatoric efficiency of random forests to identify biomarker interactions. BMC bioinformatics, 21(1), 374. (Read full article)
  84. Yang X, Lee Y, Huang Y, Chen JL, Xing RH, Lussier Y (2010). Stromal microenvironment processes unveiled by biological component analysis of gene expression in xenograft tumor models. BMC bioinformatics, 11 Suppl 9, S11. (Read full article)
  85. Yang X, Huang Y, Chen JL, Xie J, Sun X, Lussier Y (2009). Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia. BMC bioinformatics, 10 Suppl 9, S6. (Read full article)
  86. Lussier YA, Sarkar I (2009). Selected proceedings of the 2009 Summit on Translational Bioinformatics. BMC bioinformatics, 10 Suppl 9, I1. (Read full article)
  87. Sam LT, Mendonça EA, Li J, Blake J, Friedman C, Lussier Y (2009). PhenoGO: an integrated resource for the multiscale mining of clinical and biological data. BMC bioinformatics, 10 Suppl 2, S8. (Read full article)
  88. Liu Y, Sam L, Li J, Lussier Y (2009). Robust methods for accurate diagnosis using pan-microbiological oligonucleotide microarrays. BMC bioinformatics, 10 Suppl 2, S11. (Read full article)
  89. Butte AJ, Sarkar IN, Ramoni M, Lussier Y, Troyanskaya (2009). Selected proceedings of the First Summit on Translational Bioinformatics 2008. BMC bioinformatics, 10 Suppl 2, I1. (Read full article)
  90. Chen JL, Liu Y, Sam LT, Li J, Lussier Y (2007). Evaluation of high-throughput functional categorization of human disease genes. BMC bioinformatics, 8 Suppl 3, S7. (Read full article)
  91. Goh CS, Gianoulis TA, Liu Y, Li J, Paccanaro A, Lussier YA, Gerstein (2006). Integration of curated databases to identify genotype-phenotype associations. BMC genomics, 7, 257. (Read full article)
  92. Bime C, Casanova N, Oita RC, Ndukum J, Lynn H, Camp SM, Lussier Y, Abraham I, Carter D, Miller EJ, Mekontso-Dessap A, Downs CA, Garcia JG (2019). Development of a biomarker mortality risk model in acute respiratory distress syndrome. Critical care (London, England), 23(1), 410. (Read full article)
  93. Lussier YA, Li (2012). The rise of translational bioinformatics. Genome biology, 13(8), 319. (Read full article)
  94. Vitali F, Li Q, Schissler AG, Berghout J, Kenost C, Lussier Y (2019). Developing a 'personalome' for precision medicine: emerging methods that compute interpretable effect sizes from single-subject transcriptomes. Briefings in bioinformatics, 20(3), 789-805. (Read full article)
  95. Li Q, Schissler AG, Gardeux V, Berghout J, Achour I, Kenost C, Li H, Zhang HH, Lussier Y (2017). kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects. Journal of biomedical informatics, 66, 32-41. (Read full article)
  96. Li H, Pouladi N, Achour I, Gardeux V, Li J, Li Q, Zhang HH, Martinez FD, 'Skip' Garcia JGN, Lussier Y (2015). eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs. Journal of biomedical informatics, 58, 226-234. (Read full article)
  97. Gardeux V, Bosco A, Li J, Halonen MJ, Jackson D, Martinez FD, Lussier Y (2015). Towards a PBMC "virogram assay" for precision medicine: Concordance between ex vivo and in vivo viral infection transcriptomes. Journal of biomedical informatics, 55, 94-103. (Read full article)
  98. Lussier YA, Li (2012). Breakthroughs in genomics data integration for predicting clinical outcome. Journal of biomedical informatics, 45(6), 1199-201. (Read full article)
  99. Yang X, Huang Y, Crowson M, Li J, Maitland ML, Lussier Y (2010). Kinase inhibition-related adverse events predicted from in vitro kinome and clinical trial data. Journal of biomedical informatics, 43(3), 376-84. (Read full article)
  100. Chen J, Sam L, Huang Y, Lee Y, Li J, Liu Y, Xing HR, Lussier Y (2010). Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures. Journal of biomedical informatics, 43(3), 385-96. (Read full article)
  101. Tulipano PK, Tao Y, Millar WS, Zanzonico P, Kolbert K, Xu H, Yu H, Chen L, Lussier YA, Friedman (2007). Natural language processing and visualization in the molecular imaging domain. Journal of biomedical informatics, 40(3), 270-81. (Read full article)
  102. Zhou L, Tao Y, Cimino JJ, Chen ES, Liu H, Lussier YA, Hripcsak G, Friedman (2006). Terminology model discovery using natural language processing and visualization techniques. Journal of biomedical informatics, 39(6), 626-36. (Read full article)
  103. Liu H, Lussier YA, Friedman (2001). Disambiguating ambiguous biomedical terms in biomedical narrative text: an unsupervised method. Journal of biomedical informatics, 34(4), 249-61. (Read full article)
  104. Huang Y, Ma SF, Vij R, Oldham JM, Herazo-Maya J, Broderick SM, Strek ME, White SR, Hogarth DK, Sandbo NK, Lussier YA, Gibson KF, Kaminski N, Garcia JG, Noth (2015). A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis. BMC pulmonary medicine, 15, 147. (Read full article)
  105. Payne PR, Lussier Y, Foraker RE, Embi P (2016). Rethinking the role and impact of health information technology: informatics as an interventional discipline. BMC medical informatics and decision making, 16, 40. (Read full article)
  106. Payne PR, Pressler TR, Sarkar IN, Lussier (2013). People, organizational, and leadership factors impacting informatics support for clinical and translational research. BMC medical informatics and decision making, 13, 20. (Read full article)
  107. Casanova NG, Gonzalez-Garay ML, Sun B, Bime C, Sun X, Knox KS, Crouser ED, Sammani N, Gonzales T, Natt B, Chaudhary S, Lussier Y, Garcia JG (2020). Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas. Respiratory research, 21(1), 321. (Read full article)
  108. Choi J, Bakken S, Lussier YA, Mendonça E (2006). Improving the human readability of Arden Syntax medical logic modules using a concept-oriented terminology and object-oriented programming expressions. Computers, informatics, nursing, 24(4), 220-5. (Read full article)
  109. Moreno-Vinasco L, Gomberg-Maitland M, Maitland ML, Desai AA, Singleton PA, Sammani S, Sam L, Liu Y, Husain AN, Lang RM, Ratain MJ, Lussier YA, Garcia J (2008). Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension. Physiological genomics, 33(2), 278-91. (Read full article)
  110. Li Q, Zaim SR, Aberasturi D, Berghout J, Li H, Vitali F, Kenost C, Zhang HH, Lussier Y (2020). Interpretation of 'Omics dynamics in a single subject using local estimates of dispersion between two transcriptomes. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2019, 582-591. (Read full article)
  111. Fan JW, Lussier Y (2018). Word-of-Mouth Innovation: Hypothesis Generation for Supplement Repurposing based on Consumer Reviews. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2017, 689-695. (Read full article)
  112. Lee YJ, Boyd AD, Li JJ, Gardeux V, Kenost C, Saner D, Li H, Abraham I, Krishnan JA, Lussier Y (2014). COPD Hospitalization Risk Increased with Distinct Patterns of Multiple Systems Comorbidities Unveiled by Network Modeling. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2014, 855-64. (Read full article)
  113. Yang X, Li H, Regan K, Li J, Huang Y, Lussier Y (2012). Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2012, 1040-9. (Read full article)
  114. Chard K, Russell M, Lussier YA, Mendonça EA, Silverstein J (2011). A cloud-based approach to medical NLP. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2011, 207-16. (Read full article)
  115. Sam L, Borlawsky T, Tao Y, Li J, Friedman C, Smith B, Lussier Y (2007). Information-theoretic classification of SNOMED improves the organization of context-sensitive excerpts from Cochrane reviews. AMIA ... Annual Symposium proceedings. AMIA Symposium, 1100. (Read full article)
  116. Liu Y, Sam L, Li J, Lussier Y (2007). Robust informatics methods for accurate diagnosis using highly multiplexed virus arrays. AMIA ... Annual Symposium proceedings. AMIA Symposium, 1039. (Read full article)
  117. Chen ES, Borlawsky T, Qureshi K, Li J, Lussier YA, Hripcsak (2007). Monitoring the function and use of a clinical decision support system. AMIA ... Annual Symposium proceedings. AMIA Symposium, 902. (Read full article)
  118. Chen ES, Stetson PD, Lussier YA, Markatou M, Hripcsak G, Friedman (2007). Detection of practice pattern trends through Natural Language Processing of clinical narratives and biomedical literature. AMIA ... Annual Symposium proceedings. AMIA Symposium, 120-4. (Read full article)
  119. Borlawsky T, Friedman C, Lussier Y (2006). Generating executable knowledge for evidence-based medicine using natural language and semantic processing. AMIA ... Annual Symposium proceedings. AMIA Symposium, 56-60. (Read full article)
  120. Tulipano PK, Tao Y, Zanzonico P, Kolbert K, Lussier Y, Friedman (2005). Natural language processing in the molecular imaging domain. AMIA ... Annual Symposium proceedings. AMIA Symposium, 1143. (Read full article)
  121. Borlawsky T, Li J, Jalan S, Stern E, Williams R, Lussier Y (2005). Partitioning knowledge bases between advanced notification and clinical decision support systems. AMIA ... Annual Symposium proceedings. AMIA Symposium, 901. (Read full article)
  122. Tao Y, Mendonca EA, Lussier Y (2003). A "systematics" tool for medical terminologies. AMIA ... Annual Symposium proceedings. AMIA Symposium, 1028. (Read full article)
  123. Kuo TH, Mendonca EA, Li J, Lussier Y (2003). Guideline interaction: a study of interactions among drug-disease contraindication rules. AMIA ... Annual Symposium proceedings. AMIA Symposium, 901. (Read full article)
  124. Choi J, Lussier YA, Mendoça E (2003). Adapting current Arden Syntax knowledge for an object oriented event monitor. AMIA ... Annual Symposium proceedings. AMIA Symposium, 814. (Read full article)
  125. Cantor MN, Lussier Y (2003). Putting data integration into practice: using biomedical terminologies to add structure to existing data sources. AMIA ... Annual Symposium proceedings. AMIA Symposium, 125-9. (Read full article)
  126. Lee Y, Gamazon ER, Rebman E, Lee Y, Lee S, Dolan ME, Cox NJ, Lussier Y (2012). Variants affecting exon skipping contribute to complex traits. PLoS genetics, 8(10), e1002998. (Read full article)
  127. Lussier YA, Liu (2007). Computational approaches to phenotyping: high-throughput phenomics. Proceedings of the American Thoracic Society, 4(1), 18-25. (Read full article)
  128. Yang X, Regan K, Huang Y, Zhang Q, Li J, Seiwert TY, Cohen EE, Xing HR, Lussier Y (2012). Single sample expression-anchored mechanisms predict survival in head and neck cancer. PLoS computational biology, 8(1), e1002350. (Read full article)
  129. Lee Y, Yang X, Huang Y, Fan H, Zhang Q, Wu Y, Li J, Hasina R, Cheng C, Lingen MW, Gerstein MB, Weichselbaum RR, Xing HR, Lussier Y (2010). Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis. PLoS computational biology, 6(4), e1000730. (Read full article)
  130. Liu Y, Li J, Sam L, Goh CS, Gerstein M, Lussier Y (2006). An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits. PLoS computational biology, 2(11), e159. (Read full article)
  131. Grief SN, Patel J, Kochendorfer KM, Green LA, Lussier YA, Li J, Burton M, Boyd A (2016). Simulation of ICD-9 to ICD-10-CM Transition for Family Medicine: Simple or Convoluted?. Journal of the American Board of Family Medicine, 29(1), 29-36. (Read full article)
  132. Casanova NG, Zhou T, Gonzalez-Garay ML, Lussier YA, Sweiss N, Ma SF, Noth I, Knox KS, Garcia JG (2021). MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival. Translational research, 228, 1-12. (Read full article)
  133. Pouladi N, Bime C, Garcia JGN, Lussier Y (2016). Complex genetics of pulmonary diseases: lessons from genome-wide association studies and next-generation sequencing. Translational research, 168, 22-39. (Read full article)
  134. Pantazatos SP, Li J, Pavlidis P, Lussier Y (2009). Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes. Cancer informatics, 8, 75-94. (Read full article)
  135. Lussier YA, Khodarev NN, Regan K, Corbin K, Li H, Ganai S, Khan SA, Gnerlich JL, Darga TE, Fan H, Karpenko O, Paty PB, Posner MC, Chmura SJ, Hellman S, Ferguson MK, Weichselbaum R (2012). Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs. PloS one, 7(12), e50141. (Read full article)
  136. Ferreira CM, Chen JL, Li J, Shimomura K, Yang X, Lussier YA, Pinto LH, Solway (2012). Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PloS one, 7(1), e29579. (Read full article)
  137. Lussier YA, Xing HR, Salama JK, Khodarev NN, Huang Y, Zhang Q, Khan SA, Yang X, Hasselle MD, Darga TE, Malik R, Fan H, Perakis S, Filippo M, Corbin K, Lee Y, Posner MC, Chmura SJ, Hellman S, Weichselbaum R (2011). MicroRNA expression characterizes oligometastasis(es). PloS one, 6(12), e28650. (Read full article)
  138. Gamazon ER, Im HK, Duan S, Lussier YA, Cox NJ, Dolan ME, Zhang (2010). Exprtarget: an integrative approach to predicting human microRNA targets. PloS one, 5(10), e13534. (Read full article)
  139. Rachid Zaim S, Kenost C, Berghout J, Vitali F, Zhang HH, Lussier Y (2019). Evaluating single-subject study methods for personal transcriptomic interpretations to advance precision medicine. BMC medical genomics, 12(Suppl 5), 96. (Read full article)
  140. Li H, Fan J, Vitali F, Berghout J, Aberasturi D, Li J, Wilson L, Chiu W, Pumarejo M, Han J, Kenost C, Koripella PC, Pouladi N, Billheimer D, Bedrick EJ, Lussier Y (2018). Novel disease syndromes unveiled by integrative multiscale network analysis of diseases sharing molecular effectors and comorbidities. BMC medical genomics, 11(Suppl 6), 112. (Read full article)
  141. Li Q, Schissler AG, Gardeux V, Achour I, Kenost C, Berghout J, Li H, Zhang HH, Lussier Y (2017). N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes. BMC medical genomics, 10(Suppl 1), 27. (Read full article)
  142. Yang X, Huang Y, Lee Y, Gardeux V, Achour I, Regan K, Rebman E, Li H, Lussier Y (2014). In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment. BMC medical genomics, 7 Suppl 1, S2. (Read full article)
  143. Gardeux V, Arslan AD, Achour I, Ho TT, Beck WT, Lussier Y (2014). Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study. BMC medical genomics, 7 Suppl 1, S1. (Read full article)
  144. Chen JL, Hsu A, Yang X, Li J, Lee Y, Parinandi G, Li H, Lussier Y (2013). Curation-free biomodules mechanisms in prostate cancer predict recurrent disease. BMC medical genomics, 6 Suppl 2, S4. (Read full article)
  145. Pouladi N, Achour I, Li H, Berghout J, Kenost C, Gonzalez-Garay ML, Lussier Y (2016). Biomechanisms of Comorbidity: Reviewing Integrative Analyses of Multi-omics Datasets and Electronic Health Records. Yearbook of medical informatics, (1), 194-206. (Read full article)
  146. Venepalli NK, Qamruzzaman Y, Li JJ, Lussier YA, Boyd A (2014). Identifying clinically disruptive International Classification of Diseases 10th Revision Clinical Modification conversions to mitigate financial costs using an online tool. Journal of oncology practice, 10(2), 97-103. (Read full article)
  147. Herazo-Maya JD, Noth I, Duncan SR, Kim S, Ma SF, Tseng GC, Feingold E, Juan-Guardela BM, Richards TJ, Lussier Y, Huang Y, Vij R, Lindell KO, Xue J, Gibson KF, Shapiro SD, Garcia JG, Kaminski (2013). Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis. Science translational medicine, 5(205), 205ra136. (Read full article)
  148. Lussier YA, Chen J (2011). The emergence of genome-based drug repositioning. Science translational medicine, 3(96), 96ps35. (Read full article)
  149. Lee Y, Li J, Gamazon E, Chen JL, Tikhomirov A, Cox NJ, Lussier Y (2010). Biomolecular Systems of Disease Buried Across Multiple GWAS Unveiled by Information Theory and Ontology. Summit on translational bioinformatics, 2010, 31-5. (Read full article)
  150. Borlawsky TB, Li J, Shagina L, Crowson MG, Liu Y, Friedman C, Lussier Y (2010). Evaluation of an Ontology-anchored Natural Language-based Approach for Asserting Multi-scale Biomolecular Networks for Systems Medicine. Summit on translational bioinformatics, 2010, 6-10. (Read full article)
  151. Pantazatos SP, Li J, Pavlidis P, Lussier Y (2009). Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes. Summit on translational bioinformatics, 2009, 85-9. (Read full article)
  152. Vitali F, Marini S, Balli M, Grosemans H, Sampaolesi M, Lussier YA, Cusella De Angelis MG, Bellazzi (2017). Exploring Wound-Healing Genomic Machinery with a Network-Based Approach. Pharmaceuticals (Basel, Switzerland), 10(2), (Read full article)
  153. Boyd AD, Li J', Kenost C, Zaim SR, Krive J, Mittal M, Satava RA, Burton M, Smith J, Lussier Y (2018). ICD-10 procedure codes produce transition challenges. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2017, 35-44. (Read full article)
  154. Embi PJ, Tachinardi U, Lussier Y, Starren J, Silverstein (2013). Integrating Governance of Research Informatics and Health Care IT Across an Enterprise: Experiences from the Trenches. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2013, 60-2. (Read full article)
  155. Tao Y, Liu Y, Friedman C, Lussier Y (2004). Information Visualization Techniques in Bioinformatics during the Postgenomic Era. Drug discovery today. Biosilico, 2(6), 237-245. (Read full article)
  156. Williams R, Jalan S, Stern E, Lussier Y (2005). Cascading Policies Provide Fault Tolerance for Pervasive Clinical Communications. Proceedings of the ... IEEE International Conference on Pervasive Computing and Communications. IEEE International Conference on Pervasive Computing and Communications, 2005, 209-212. (Read full article)
  157. Schissler AG, Aberasturi D, Kenost C, Lussier Y (2019). A Single-Subject Method to Detect Pathways Enriched With Alternatively Spliced Genes. Frontiers in genetics, 10, 414. (Read full article)
  158. Zhou T, Casanova N, Pouladi N, Wang T, Lussier Y, Knox KS, Garcia JG (2017). Identification of Jak-STAT signaling involvement in sarcoidosis severity via a novel microRNA-regulated peripheral blood mononuclear cell gene signature. Scientific reports, 7(1), 4237. (Read full article)
  159. Fan JW, Li J, Lussier Y (2017). Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context. Journal of healthcare engineering, 2017, 3818302. (Read full article)
  160. Rachid Zaim S, Kenost C, Zhang HH, Lussier Y (2020). Personalized beyond Precision: Designing Unbiased Gold Standards to Improve Single-Subject Studies of Personal Genome Dynamics from Gene Products. Journal of personalized medicine, 11(1), (Read full article)
  161. Han MK, Zhou Y, Murray S, Tayob N, Noth I, Lama VN, Moore BB, White ES, Flaherty KR, Huffnagle GB, Martinez FJ, COMET Investigators (2014). Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study. The Lancet. Respiratory medicine, 2(7), 548-56. (Read full article)
  162. Li H, Achour I, Bastarache L, Berghout J, Gardeux V, Li J, Lee Y, Pesce L, Yang X, Ramos KS, Foster I, Denny JC, Moore JH, Lussier Y (2016). Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. NPJ genomic medicine, 1, (Read full article)
  163. Li H, Baldwin E, Zhang X, Kenost C, Luo W, Calhoun EA, An L, Bennett CL, Lussier Y (2021). Comparison and impact of COVID-19 for patients with cancer: a survival analysis of fatality rate controlling for age, sex and cancer type. BMJ health & care informatics, 28(1), (Read full article)
  164. Chang EH, Pouladi N, Guerra S, Jandova J, Kim A, Li H, Li J, Morgan W, Stern DA, Willis AL, Lussier YA, Martinez F (2022). Epithelial cell responses to rhinovirus identify an early-life-onset asthma phenotype in adults. The Journal of allergy and clinical immunology, (Read full article)

Editorial

  1. Lussier YA, Butte AJ, Hunter (2010). Current methodologies for translational bioinformatics. Journal of biomedical informatics, 43(3), 355-7. (Read full article)
  2. Atun R, Lussier Y, Poon C, Wong ST, Yang G (2015). Editorial: big data for health. IEEE journal of biomedical and health informatics, 19(4), 1191-2. (Read full article)

Letter

  1. Chang EH, Willis AL, Romanoski CE, Cusanovich DA, Pouladi N, Li J, Lussier YA, Martinez F (2020). Rhinovirus Infections in Individuals with Asthma Increase ACE2 Expression and Cytokine Pathways Implicated in COVID-19. American journal of respiratory and critical care medicine, 202(5), 753-755. (Read full article)

Other

  1. Berghout J, Lussier YA, Vitali F, Bulyk ML, Kann MG, Moore J (2019). Workshop during the Pacific Symposium of Biocomputing, Jan 3-7, 2019: Reading between the genes: interpreting non-coding DNA in high-throughput. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 24, 444-448. (Read full article)
  2. Lussier YA, Li H, Pouladi N, Li (2014). Accelerating precision biology and medicine with computational biology and bioinformatics. Genome biology, 15(9), 450. (Read full article)
  3. Lussier YA, Li H, Maienschein-Cline (2013). Conquering computational challenges of omics data and post-ENCODE paradigms. Genome biology, 14(8), 310. (Read full article)
  4. Aberasturi D, Pouladi N, Zaim SR, Kenost C, Berghout J, Piegorsch WW, Lussier Y (2021). 'Single-subject studies'-derived analyses unveil altered biomechanisms between very small cohorts: implications for rare diseases. Bioinformatics (Oxford, England), 37(Suppl_1), i67-i75. (Read full article)